{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,2]],"date-time":"2025-12-02T22:40:39Z","timestamp":1764715239884,"version":"3.41.2"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2024,7,6]],"date-time":"2024-07-06T00:00:00Z","timestamp":1720224000000},"content-version":"vor","delay-in-days":187,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012041","name":"Versus Arthritis","doi-asserted-by":"publisher","award":["19634"],"award-info":[{"award-number":["19634"]}],"id":[{"id":"10.13039\/501100012041","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006662","name":"NIHR","doi-asserted-by":"publisher","award":["NIHR300826"],"award-info":[{"award-number":["NIHR300826"]}],"id":[{"id":"10.13039\/100006662","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100022244","name":"NIHR Applied Research Collaboration West Midlands","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100022244","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,6,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objective<\/jats:title>\n                  <jats:p>To examine the association between obesity and patient-reported outcome measures (PROMs) in a primary care-based cohort of people with PMR.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>The PMR Cohort Study recruited people with incident PMR from 382 general practices. Self-completed questionnaires (0, 12, 24 months) captured a range of PROMs for pain, stiffness, anxiety, depression, fatigue, function and quality of life, alongside data on BMI. People were categorized as underweight\/normal weight (BMI\u2009&amp;lt;\u200925kg\/m2), overweight (25\u201329.99\u2009kg\/m2) or obese (\u226530\u2009kg\/m2). Piecewise, multilevel, linear mixed-effects regression models examined relationships between BMI categories and PROMs over time, adjusting for confounding variables. Chi-squared tests examined the relationship between obesity and glucocorticoid persistence.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>644 people with PMR were included. At baseline, 33.9% were normal\/underweight, 40.6% overweight and 25.5% obese. Compared with normal\/underweight people, those with obesity had significantly worse scores for the following: pain and stiffness at 12 months; fatigue at 12 and 24 months; depression at baseline; physical function at all time points; and quality of life at baseline and 12 months. They also had significantly smaller improvements in stiffness (1.13 units on an 11-point numeric rating scale; P\u2009=\u20090.001) and physical function (0.14 units measured using the modified Health Assessment Questionnaire; P\u2009=\u20090.025) between 0 and 12 months. BMI categories did not relate to persistent glucocorticoid use at 12 months (P\u2009=\u20090.110) or 24 months (P\u2009=\u20090.166).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Obesity associates with poorer outcomes for a range of PROMs in people with PMR. Consideration should be given to providing weight management support to people with PMR and obesity.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/rap\/rkae081","type":"journal-article","created":{"date-parts":[[2024,7,6]],"date-time":"2024-07-06T08:04:50Z","timestamp":1720253090000},"source":"Crossref","is-referenced-by-count":2,"title":["The relationship between obesity and patient-reported outcome measures in people with polymyalgia rheumatica"],"prefix":"10.1093","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1268-9808","authenticated-orcid":false,"given":"Ian C","family":"Scott","sequence":"first","affiliation":[{"name":"Primary Care Centre Versus Arthritis, School of Medicine, Keele University , Keele, UK"},{"name":"Haywood Academic Rheumatology Centre, Haywood Hospital, Midlands Partnership University NHS Foundation Trust , Staffordshire, 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