{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T19:05:59Z","timestamp":1784833559985,"version":"3.55.0"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T00:00:00Z","timestamp":1783296000000},"content-version":"vor","delay-in-days":186,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Vaccination rates among patients with RA or SpA remain suboptimal. This study examined the uptake of pneumococcal and influenza vaccines among patients undergoing immunosuppressive therapy and receiving annual nurse-led education.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Patients with RA or SpA who initiated their first biologic therapy between 2015 and 2017 and attended yearly visits with a rheumatologist and a therapeutic patient education (TPE) nurse over 5\u2009years were included. Adherence to pneumococcal and influenza vaccine recommendations and factors associated with vaccine uptake were assessed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 156 patients were analysed: 60 RA and 96 SpA. Overall, 81% (95% CI 74, 87) adhered to the 5-year pneumococcal vaccination recommendations (82% in RA and 80% in SpA). Among patients with RA, a history of major adverse cardiac events or deep vein thrombosis\/pulmonary embolism at baseline and the occurrence of myocardial infarction or stent placement during follow-up were associated with non-adherence. Among patients with SpA, those who experienced infections during follow-up were more likely to adhere to the pneumococcal vaccination recommendations. Between 2015 and 2022, influenza vaccination rates increased from 63% to 73% in RA and from 33% to 47% in SpA. However, only 22% of patients were vaccinated annually over 5\u2009years (22% RA, 22% SpA), while 19% never received this vaccine. Older age was associated with higher influenza vaccination uptake in both groups. In SpA, experiencing infections during follow-up was associated with higher influenza vaccination rates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Pneumococcal vaccination coverage was high among patients monitored annually by a TPE nurse. Influenza vaccination coverage improved over time but remained insufficient, particularly among patients with SpA.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/rap\/rkag075","type":"journal-article","created":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T15:28:05Z","timestamp":1783351685000},"source":"Crossref","is-referenced-by-count":0,"title":["Pneumococcal and influenza vaccination coverage in patients with inflammatory rheumatic diseases receiving immunosuppressive therapy and annual nurse-led education"],"prefix":"10.1093","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5491-2262","authenticated-orcid":false,"given":"Fran\u00e7oise","family":"Fayet","sequence":"first","affiliation":[{"name":"Rheumatology Department, CHU Clermont-Ferrand , Clermont-Ferrand,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9line","family":"Lambert","sequence":"additional","affiliation":[{"name":"Biostatistics Unit, DRCI, CHU Clermont-Ferrand , Clermont-Ferrand,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ang\u00e9lique","family":"Fan","sequence":"additional","affiliation":[{"name":"Rheumatology Department, CHU Clermont-Ferrand , Clermont-Ferrand,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-H\u00e9l\u00e8ne","family":"Salembien","sequence":"additional","affiliation":[{"name":"Rheumatology Department, CHU Clermont-Ferrand , Clermont-Ferrand,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Coralie","family":"Yvars","sequence":"additional","affiliation":[{"name":"Rheumatology Department, CHU Clermont-Ferrand , Clermont-Ferrand,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Malory","family":"Rodere","sequence":"additional","affiliation":[{"name":"Rheumatology Department, CHU Clermont-Ferrand , Clermont-Ferrand,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carine","family":"Savel","sequence":"additional","affiliation":[{"name":"Rheumatology Department, CHU Clermont-Ferrand , Clermont-Ferrand,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elodie","family":"Vandemeulebroucke","sequence":"additional","affiliation":[{"name":"Rheumatology Department, CHU Clermont-Ferrand , Clermont-Ferrand,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion","family":"Guittard","sequence":"additional","affiliation":[{"name":"Rheumatology Department, CHU Clermont-Ferrand , Clermont-Ferrand,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8632-4967","authenticated-orcid":false,"given":"Natacha","family":"Mrozek","sequence":"additional","affiliation":[{"name":"Infectious and Tropical Diseases Department, CHU Clermont-Ferrand , Clermont-Ferrand,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Tournadre","sequence":"additional","affiliation":[{"name":"Rheumatology Department, CHU Clermont-Ferrand , Clermont-Ferrand,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Soubrier","sequence":"additional","affiliation":[{"name":"Rheumatology Department, CHU Clermont-Ferrand , Clermont-Ferrand,","place":["France"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,7,6]]},"reference":[{"key":"2026072314221669500_rkag075-B1","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1002\/acr.25045","article-title":"2022 American College of Rheumatology guideline for vaccinations in patients with rheumatic and musculoskeletal diseases","volume":"75","author":"Bass","year":"2023","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"2026072314221669500_rkag075-B2","doi-asserted-by":"publisher","first-page":"1446","DOI":"10.1016\/j.vaccine.2015.01.065","article-title":"Low rate of influenza and pneumococcal vaccine coverage in rheumatoid arthritis: data from the international COMORA cohort","volume":"33","author":"Hmamouchi","year":"2015","journal-title":"Vaccine."},{"key":"2026072314221669500_rkag075-B3","doi-asserted-by":"publisher","first-page":"1016","DOI":"10.1136\/annrheumdis-2015-208174","article-title":"Prevalence of comorbidities and evaluation of their screening in spondyloarthritis: results of the international cross-sectional ASAS-COMOSPA study","volume":"75","author":"Molt\u00f3","year":"2016","journal-title":"Ann Rheum Dis"},{"key":"2026072314221669500_rkag075-B4","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/j.jbspin.2015.11.005","article-title":"Influenza and pneumococcal vaccine coverage in 584 patients taking biological therapy for chronic inflammatory joint: a retrospective study","volume":"83","author":"Brocq","year":"2016","journal-title":"Joint Bone Spine"},{"key":"2026072314221669500_rkag075-B5","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1007\/s00296-016-3608-y","article-title":"Low vaccination rates among patients with rheumatoid arthritis in a German outpatient clinic","volume":"37","author":"Krasselt","year":"2017","journal-title":"Rheumatol Int"},{"key":"2026072314221669500_rkag075-B6","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.reumae.2021.11.003","article-title":"Vaccination against influenza and pneumococus in patients with rheumatoid arthritis","volume":"19","author":"Tobar-Marcillo","year":"2023","journal-title":"Reumatol Clin (Engl Ed)"},{"key":"2026072314221669500_rkag075-B7","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1186\/s12891-016-1187-4","article-title":"A large two-centre study in to rates of influenza and pneumococcal vaccination and infection burden in rheumatoid arthritis in the UK","volume":"17","author":"Subesinghe","year":"2016","journal-title":"BMC Musculoskelet Disord"},{"key":"2026072314221669500_rkag075-B8","doi-asserted-by":"publisher","first-page":"165","DOI":"10.1007\/s00296-023-05476-2","article-title":"Adoption rates of recommended vaccines and influencing factors among patients with inflammatory arthritis: a patient survey","volume":"44","author":"Moraliyska","year":"2024","journal-title":"Rheumatol Int"},{"key":"2026072314221669500_rkag075-B9","doi-asserted-by":"publisher","first-page":"1593","DOI":"10.1016\/j.vaccine.2021.02.009","article-title":"A clinical audit of pneumococcal vaccination among patients with autoimmune rheumatic diseases living in Greece: the power of awareness","volume":"39","author":"Constantinou","year":"2021","journal-title":"Vaccine"},{"key":"2026072314221669500_rkag075-B10","doi-asserted-by":"crossref","first-page":"2479","DOI":"10.1093\/rheumatology\/keae305","article-title":"Pneumococcal vaccine uptake in patients with inflammatory arthritis: a single centre cohort study","volume":"64","author":"Nagra","year":"2025","journal-title":"Rheumatology (Oxford)"},{"key":"2026072314221669500_rkag075-B11","doi-asserted-by":"publisher","first-page":"61","DOI":"10.1136\/annrheumdis-2019-215458","article-title":"2018 update of the EULAR recommendations for the role of the nurse in the management of chronic inflammatory arthritis","volume":"79","author":"Bech","year":"2020","journal-title":"Ann Rheum Dis"},{"key":"2026072314221669500_rkag075-B12","doi-asserted-by":"publisher","first-page":"954","DOI":"10.1136\/annrheumdis-2014-206807","article-title":"EULAR recommendations for patient education for people with inflammatory arthritis","volume":"74","author":"Zangi","year":"2015","journal-title":"Ann Rheum Dis"},{"key":"2026072314221669500_rkag075-B13","doi-asserted-by":"publisher","first-page":"2569","DOI":"10.1002\/art.27584","article-title":"2010 rheumatoid arthritis classification criteria: an American College of Rheumatology\/European League Against Rheumatism collaborative initiative","volume":"62","author":"Aletaha","year":"2010","journal-title":"Arthritis Rheum"},{"key":"2026072314221669500_rkag075-B14","doi-asserted-by":"publisher","first-page":"777","DOI":"10.1136\/ard.2009.108233","article-title":"The development of Assessment of SpondyloArthritis international Society classification criteria for axial spondyloarthritis (part II): validation and final selection","volume":"68","author":"Rudwaleit","year":"2009","journal-title":"Ann Rheum Dis"},{"key":"2026072314221669500_rkag075-B15","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1136\/ard.2010.133645","article-title":"The Assessment of SpondyloArthritis International Society classification criteria for peripheral spondyloarthritis and for spondyloarthritis in general","volume":"70","author":"Rudwaleit","year":"2011","journal-title":"Ann Rheum Dis"},{"key":"2026072314221669500_rkag075-B16","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/1471-2288-2-8","article-title":"Do multiple outcome measures require p-value adjustment?","volume":"2","author":"Feise","year":"2002","journal-title":"BMC Med Res Methodol"},{"key":"2026072314221669500_rkag075-B17","doi-asserted-by":"publisher","first-page":"1725","DOI":"10.1136\/annrheumdis-2013-204733","article-title":"Impact of a nurse-led programme on comorbidity management and impact of a patient self-assessment of disease activity on the management of rheumatoid arthritis: results of a prospective, multicentre, randomised, controlled trial (COMEDRA)","volume":"74","author":"Dougados","year":"2015","journal-title":"Ann Rheum Dis"},{"key":"2026072314221669500_rkag075-B18","doi-asserted-by":"publisher","first-page":"701","DOI":"10.1016\/j.semarthrit.2020.05.012","article-title":"Evaluation of the impact of a nurse-led program of systematic screening of comorbidities in patients with axial spondyloarthritis: the results of the COMEDSPA prospective, controlled, one year randomized trial","volume":"50","author":"Molto","year":"2020","journal-title":"Semin Arthritis Rheum"},{"key":"2026072314221669500_rkag075-B19","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1007\/s00296-025-05870-y","article-title":"Low vaccination rates and awareness status in patients with rheumatoid arthritis: a nationwide cross-sectional survey study","volume":"45","author":"Kirik","year":"2025","journal-title":"Rheumatol Int"},{"key":"2026072314221669500_rkag075-B20","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/j.jbspin.2018.06.006","article-title":"Obstacles and motivations to influenza and pneumococcal vaccination in patients with rheumatoid arthritis. A qualitative study. Comment on: \u201cPneumococcal and influenza vaccination rates in patients treated with corticosteroids and\/or immunosuppressive therapies for systemic auto-immune diseases: a cross-sectional study\u201d by Assala et al., Joint Bone Spine 2017;84:365\u20136","volume":"86","author":"Fayet","year":"2019","journal-title":"Joint Bone Spine"}],"container-title":["Rheumatology Advances in Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/rheumap\/advance-article-pdf\/doi\/10.1093\/rap\/rkag075\/68702225\/rkag075.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/rheumap\/article-pdf\/10\/3\/rkag075\/68702225\/rkag075.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/rheumap\/article-pdf\/10\/3\/rkag075\/68702225\/rkag075.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T18:26:17Z","timestamp":1784831177000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/rheumap\/article\/doi\/10.1093\/rap\/rkag075\/8725468"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":20,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,6,15]]}},"URL":"https:\/\/doi.org\/10.1093\/rap\/rkag075","relation":{},"ISSN":["2514-1775"],"issn-type":[{"value":"2514-1775","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026]]},"published":{"date-parts":[[2026]]},"article-number":"rkag075"}}