{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T16:01:59Z","timestamp":1762444919656,"version":"3.41.2"},"reference-count":23,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2019,8,14]],"date-time":"2019-08-14T00:00:00Z","timestamp":1565740800000},"content-version":"vor","delay-in-days":225,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>Despite medical advances, life-changing articular damage may still occur in patients with JIA. We report a cohort with destructive arthropathy of the ankle treated by surgical arthrodiastasis.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Eight patients (nine ankles) received arthrodiastasis by means of an Ilizarov frame between 2009 and 2013. Patient- and clinician-reported outcome measures were collated prospectively, with retrospective analysis of demographics, disease and pre-surgical treatment.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Pre-surgery, all patients received IA CS (mean 0.8 injections\/year) and MTX (mean diagnosis to treatment 3.8\u2009years; two of eight started within 3\u2009months). Seven of eight patients received biologic drugs. Pain scores improved by 56 and 29% (P\u2009&lt;\u20090.005) at 6 and 12\u00a0months post-frame removal. American Academy Orthopaedic Foot and Ankle Society ankle\u2013hindfoot scale, Oxford Ankle Foot Questionnaire-Child and Oxford Ankle Foot Questionnaire-Parent scores improved by 171, 62 and 80%, respectively (P\u2009&lt;\u20090.005) at 12\u2009months post-frame removal. Patients remained satisfied with surgical treatment for a mean of 13.3\u2009months. There was transient pin site infection in three patients, and all patients had radiological improvement in joint space.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>Arthrodiastasis with an Ilizarov frame is a safe, well-tolerated technique that should be considered as a short-term joint-preserving procedure to improve pain and function when damage has occurred. Delays to systemic medical treatment in this cohort would be considered out-with standard modern practice but, although less prevalent, destructive ankle arthropathy continues to occur in JIA, and we believe this study to be relevant. The ankle is particularly susceptible to damage and, even if localized, should be treated early and aggressively with DMARDs and rapid progression to biologic therapies.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Levelof evidence<\/jats:title>\n                  <jats:p>Level IV.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/rap\/rkz031","type":"journal-article","created":{"date-parts":[[2019,8,14]],"date-time":"2019-08-14T22:24:21Z","timestamp":1565821461000},"source":"Crossref","is-referenced-by-count":3,"title":["Short-term outcome of surgical arthrodiastasis of the ankle with Ilizarov frame in a cohort of children and young people with juvenile idiopathic arthritis"],"prefix":"10.1093","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8676-0355","authenticated-orcid":false,"given":"Gavin","family":"Cleary","sequence":"first","affiliation":[{"name":"Alder Hey Children\u2019s Hospital NHS Foundation Trust, Liverpool"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clare","family":"Pain","sequence":"additional","affiliation":[{"name":"Alder Hey Children\u2019s Hospital NHS Foundation Trust, Liverpool"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liza","family":"McCann","sequence":"additional","affiliation":[{"name":"Alder Hey Children\u2019s Hospital NHS Foundation Trust, Liverpool"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kamran","family":"Mahmood","sequence":"additional","affiliation":[{"name":"Alder Hey Children\u2019s Hospital NHS Foundation Trust, Liverpool"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Brookes-Fazakerley","sequence":"additional","affiliation":[{"name":"Alder Hey Children\u2019s Hospital NHS Foundation Trust, Liverpool"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simon","family":"Robinson","sequence":"additional","affiliation":[{"name":"Arrowe Park 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