{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T17:01:04Z","timestamp":1792083664640,"version":"4.4.0"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2021,1,4]],"date-time":"2021-01-04T00:00:00Z","timestamp":1609718400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,3,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Porcine small intestine submucosa (SIS) biologic patch has been used in inguinal hernia repair. However, there are little data available to assess the long-term effect after repair. This study aimed to explore the long-term effect of SIS patch in open inguinal hernia repair. Sevent-six patients with unilateral inguinal hernia were treated with Lichtenstein tension-free hernia repair using SIS patch (Beijing Datsing Bio-Tech Co., Ltd.) and Surgisis patch (COOK, USA) in Tianjin Union Medical Center and China-Japan Friendship Hospital. In the trial, the long-term efficacy of the treatment group and the control group were compared. A total of 66 patients in both groups received long-term follow-up (&amp;gt; 5\u2009years) after surgery, with a follow-up rate of 86.8%. During the follow-up period, there was one case of recurrence, one case of chronic pain in the control group. There was no statistically significant difference (P\u2009&amp;gt;\u20090.05) in terms of recurrence, chronic pain, foreign body sensation and infection between the two groups of patients. After long-term observations, it has been found that the porcine small intestinal submucosa (SIS) biological patch is safe and effective for inguinal hernia Lichtenstein repair, and has a low recurrence rate and complication rate.<\/jats:p>","DOI":"10.1093\/rb\/rbaa055","type":"journal-article","created":{"date-parts":[[2021,1,4]],"date-time":"2021-01-04T12:30:30Z","timestamp":1609763430000},"source":"Crossref","is-referenced-by-count":14,"title":["Lichtenstein\u00a0inguinal hernia repairs with porcine small intestine submucosa: a 5- year follow-up. a prospective randomized controlled study"],"prefix":"10.1093","volume":"8","author":[{"given":"Baoshan","family":"Li","sequence":"first","affiliation":[{"name":"Department\u00a0of Hernia and Abdominal Wall Surgery, Tianjin Union Medical Center, 190, jieyuan Road, HongqiaoDistrict, Tianjin 300121, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department\u00a0of Hernia and Abdominal Wall Surgery, Tianjin Union Medical Center, 190, jieyuan Road, HongqiaoDistrict, Tianjin 300121, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Man","sequence":"additional","affiliation":[{"name":"Department\u00a0of Hernia and Abdominal Wall Surgery, Tianjin Union Medical Center, 190, jieyuan Road, HongqiaoDistrict, Tianjin 300121, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiadong","family":"Xie","sequence":"additional","affiliation":[{"name":"Department\u00a0of Hernia and Abdominal Wall Surgery, Tianjin Union Medical Center, 190, jieyuan Road, HongqiaoDistrict, Tianjin 300121, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Hu","sequence":"additional","affiliation":[{"name":"Department\u00a0of Hernia and Abdominal Wall Surgery, Tianjin Union Medical Center, 190, jieyuan Road, HongqiaoDistrict, Tianjin 300121, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huang","family":"Huang","sequence":"additional","affiliation":[{"name":"Department\u00a0of Hernia and Abdominal Wall Surgery, Tianjin Union Medical Center, 190, jieyuan Road, HongqiaoDistrict, Tianjin 300121, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yinlong","family":"Wang","sequence":"additional","affiliation":[{"name":"Department\u00a0of Hernia and Abdominal Wall Surgery, Tianjin Union Medical Center, 190, jieyuan Road, HongqiaoDistrict, Tianjin 300121, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongguang","family":"Ma","sequence":"additional","affiliation":[{"name":"Department\u00a0of General Surgery, China-Japan Friendship Hospital, Sakura Garden East Street, Chaoyang District, Beijing 100029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,1,4]]},"reference":[{"key":"2021031107170678300_rbaa055-B1","doi-asserted-by":"crossref","first-page":"52","DOI":"10.3389\/fsurg.2017.00052","article-title":"Etiology of inguinal hernias: a comprehensive review","volume":"4","author":"\u00d6berg","year":"2017","journal-title":"Front Surg"},{"key":"2021031107170678300_rbaa055-B2","doi-asserted-by":"crossref","first-page":"1878","DOI":"10.1007\/s00268-015-3028-2","article-title":"Open mesh repair for inguinal hernia is safer than laparoscopic repair or open non-mesh repair: a nationwide registry study of complications","volume":"39","author":"Kouhia","year":"2015","journal-title":"World J Surg"},{"key":"2021031107170678300_rbaa055-B3","first-page":"1071","article-title":"Current status of hernia and abdominal wall surgery and innovation research and development of repairing materials [J]","volume":"17","author":"Jianxiong","year":"2018","journal-title":"Chin J Dig Surg"},{"key":"2021031107170678300_rbaa055-B4","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1111\/ans.13234","article-title":"Biologic mesh versus synthetic mesh in open inguinal hernia repair: system review and meta-analysis","volume":"85","author":"Fang","year":"2015","journal-title":"ANZ J Surg"},{"key":"2021031107170678300_rbaa055-B5","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/s00595-012-0232-7","article-title":"A new approach for transversalis fascia reinforcement in Lichtenstein's inguinal hernia repair","volume":"43","author":"Arslani","year":"2013","journal-title":"Surg Today"},{"key":"2021031107170678300_rbaa055-B6","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.amjsurg.2008.09.021","article-title":"Inguinal hernia repair with porcine small intestine submucosa: 3-year follow-up results of a randomized controlled trial of Lichtenstein's repair with polypropylene mesh versus Surgisis Inguinal Hernia Matrix","volume":"198","author":"Ansaloni","year":"2009","journal-title":"Am J Surg"},{"key":"2021031107170678300_rbaa055-B7","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/j.jamcollsurg.2014.01.043","article-title":"Biologic vs synthetic inguinal hernia repair: 1-year results of a randomized double-blinded trial","volume":"218","author":"Bochicchio","year":"2014","journal-title":"J Am Coll Surg"},{"key":"2021031107170678300_rbaa055-B8","first-page":"344","article-title":"Stage III clinical trial on the application of porcine small intestine submucosa mesh in inguinal hernia repair [J]","volume":"11","author":"Jie","year":"2017","journal-title":"Chin J Hernia Abdominal Wall Surg (Electronic Edition)"},{"key":"2021031107170678300_rbaa055-B9","first-page":"803","article-title":"The importance of biological mesh repair in adolescent inguinal hernia repair [J]","volume":"39","author":"Yan","year":"2019","journal-title":"Chin J Pract Surg"},{"key":"2021031107170678300_rbaa055-B10","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1007\/s10029-013-1076-9","article-title":"Early report of a randomized comparative clinical trial of Strattice\u2122 reconstructive tissue matrix to lightweight synthetic mesh in the repair of inguinal hernias","volume":"18","author":"Bellows","year":"2014","journal-title":"Hernia"},{"key":"2021031107170678300_rbaa055-B11","doi-asserted-by":"crossref","first-page":"e0135073","DOI":"10.1371\/journal.pone.0135073","article-title":"Comparison of porcine small intestinal submucosa versus polypropylene in open inguinal hernia repair: a systematic review and meta-analysis","volume":"10","author":"Nie","year":"2015","journal-title":"PLoS One"},{"key":"2021031107170678300_rbaa055-B12","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.2147\/TCRM.S208185","article-title":"Randomized controlled trial of Lichtenstein repair of indirect inguinal hernias with two biologic meshes from porcine small intestine submucosa","volume":"15","author":"Sun","year":"2019","journal-title":"Ther Clin Risk Manag"},{"key":"2021031107170678300_rbaa055-B13","first-page":"821","article-title":"Clinical analysis on the technique of transverse fascia reinforcement with biological mesh in young inguinal hernia patients [J]","volume":"39","author":"Shaojie","year":"2019","journal-title":"Chin J Pract Surg"},{"key":"2021031107170678300_rbaa055-B14","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1177\/1553350617697849","article-title":"Absorbable meshes in inguinal hernia surgery: a systematic review and meta-analysis","volume":"24","author":"\u00d6berg","year":"2017","journal-title":"Surg Innov"},{"key":"2021031107170678300_rbaa055-B15","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1007\/s10029-007-0225-4","article-title":"Hernia repair with porcine small-intestinal submucosa","volume":"11","author":"Ansaloni","year":"2007","journal-title":"Hernia"},{"key":"2021031107170678300_rbaa055-B16","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/s10029-019-01976-y","article-title":"Pure tissue inguinal hernia repair with the use of biological mesh: a 10-year follows up. A prospective study","volume":"24","author":"Ravo","year":"2020","journal-title":"Hernia"},{"key":"2021031107170678300_rbaa055-B17","first-page":"218","article-title":"Lichtenstein procedure for inguinal hernia: a single center experience of 5795 cases report[J]","volume":"18","author":"Yinlong","year":"2013","journal-title":"J Surg Concepts Pract"},{"key":"2021031107170678300_rbaa055-B18","first-page":"332","article-title":"Can the wounds after infected meshes removal be sutured primarily: a retrospective study [J]","volume":"32","author":"Fenglin","year":"2017","journal-title":"Chin J Gen Surg"},{"key":"2021031107170678300_rbaa055-B19","doi-asserted-by":"crossref","first-page":"133","DOI":"10.9738\/CC176","article-title":"Placement of a non-cross-linked porcine-derived acellular dermal matrix during preperitoneal laparoscopic inguinal hernia repair","volume":"98","author":"Alshkaki","year":"2013","journal-title":"Int Surg"},{"key":"2021031107170678300_rbaa055-B20","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.jfma.2013.03.007","article-title":"The use of porcine small intestine submucosa implants might be associated with a high recurrence rate following laparoscopic herniorrhaphy","volume":"114","author":"Ho","year":"2015","journal-title":"J Formos Med Assoc"}],"container-title":["Regenerative Biomaterials"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/rb\/article-pdf\/8\/1\/rbaa055\/36524617\/rbaa055.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"http:\/\/academic.oup.com\/rb\/article-pdf\/8\/1\/rbaa055\/36524617\/rbaa055.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,3,11]],"date-time":"2021-03-11T08:24:48Z","timestamp":1615451088000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/rb\/article\/doi\/10.1093\/rb\/rbaa055\/6061541"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1,4]]},"references-count":20,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,3,8]]}},"URL":"https:\/\/doi.org\/10.1093\/rb\/rbaa055","relation":{},"ISSN":["2056-3418","2056-3426"],"issn-type":[{"value":"2056-3418","type":"print"},{"value":"2056-3426","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2021,2,1]]},"published":{"date-parts":[[2021,1,4]]},"article-number":"rbaa055"}}