{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T02:47:44Z","timestamp":1790045264305,"version":"4.0.1"},"reference-count":48,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T00:00:00Z","timestamp":1781308800000},"content-version":"vor","delay-in-days":163,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2023YFC2411300"],"award-info":[{"award-number":["2023YFC2411300"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32471392"],"award-info":[{"award-number":["32471392"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32571563"],"award-info":[{"award-number":["32571563"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Advanced Materials-National Science and Technology Major Project","award":["2025ZD0619901"],"award-info":[{"award-number":["2025ZD0619901"]}]},{"name":"Sichuan Science and Technology Program","award":["2025NSFJQ0025"],"award-info":[{"award-number":["2025NSFJQ0025"]}]},{"name":"The National Clinical Key Subject of China","award":["41C42113"],"award-info":[{"award-number":["41C42113"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,22]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Diabetic wounds are characterized by prolonged hyperglycemia and associated hypoxia, induce oxidative stress and sustained inflammation, which collectively impair angiogenesis and hinder the healing process. Conventional oxygen\u2011supplying hydrogel dressings are often limited by inefficient oxygen release, poor stability, and insufficient multifunctionality. To overcome these limitations, we have designed a GelMA\u2013MnPZC multifunctional nanocomposite hydrogel dressing capable of stable and prolonged oxygen release. This hydrogel remodels the hypoxic and inflammatory wound microenvironment through sustained oxygen generation and polyphenol\u2011mediated activity, thereby creating favorable conditions for angiogenesis and tissue regeneration. The hydrogel was fabricated by embedding polydopamine\u2013manganese (PDA\u2013Mn) nanozyme\u2011modified, ZIF\u20118\u2011encapsulated CaO2 nanoparticles into a gelatin-methacryloyl (GelMA) network. The ZIF\u20118 shell enhances the stability of CaO2, while the PDA\u2011Mn nanozyme exhibits catalase\u2011like activity, together ensuring a stable and efficient self\u2011oxygenating capability under hypoxic conditions. Furthermore, the hydrogel\u2019s excellent tissue adhesion ensures long-term stable wound management. Additionally, sustained release of Zn2+ and Mn2+ ions provide potent antibacterial activity, reducing the risk of wound infection. In summary, the GelMA\u2013MnPZC hydrogel accelerates diabetic wound healing through a coordinated multifunctional mechanism, including antibacterial action, oxidative stress mitigation, hypoxia alleviation, and immunomodulation. This innovative self\u2011oxygenating hydrogel represents a promising clinical strategy for the comprehensive treatment of diabetic wounds.<\/jats:p>","DOI":"10.1093\/rb\/rbag118","type":"journal-article","created":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T11:46:59Z","timestamp":1781178419000},"source":"Crossref","is-referenced-by-count":1,"title":["A self-oxygenating polyphenol-nanozyme hydrogel remodels the inflammatory microenvironment for diabetic wound healing"],"prefix":"10.1093","volume":"13","author":[{"given":"Shangqing","family":"Huang","sequence":"first","affiliation":[{"name":"Key Laboratory of Advanced Technologies of Materials Ministry of Education, Institute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University , Chengdu 610031,","place":["China"]},{"name":"School of Materials Science and Engineering, Southwest Jiaotong University , Chengdu 610031,","place":["China"]},{"name":"Department of Gastroenterology, Chengdu Integrated TCM & Western Medicine Hospital , Chengdu 610059,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujia","family":"Zheng","sequence":"additional","affiliation":[{"name":"Key Laboratory of Advanced Technologies of Materials Ministry of Education, Institute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University , Chengdu 610031,","place":["China"]},{"name":"School of Materials Science and Engineering, Southwest Jiaotong University , Chengdu 610031,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shengxi","family":"Jiang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Advanced Technologies of Materials Ministry of Education, Institute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University , Chengdu 610031,","place":["China"]},{"name":"School of Materials Science and Engineering, Southwest Jiaotong University , Chengdu 610031,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huabin","family":"Liu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Advanced Technologies of Materials Ministry of Education, Institute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University , Chengdu 610031,","place":["China"]},{"name":"School of Materials Science and Engineering, Southwest Jiaotong University , Chengdu 610031,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijun","family":"Tang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Advanced Technologies of Materials Ministry of Education, Institute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University , Chengdu 610031,","place":["China"]},{"name":"School of Materials Science and Engineering, Southwest Jiaotong University , Chengdu 610031,","place":["China"]},{"name":"Department of General Surgery & Tissue Stress Injury and Functional Repair Key Laboratory of Sichuan Province, The General Hospital of Western Theater Command (Chengdu Military General Hospital) , Chengdu 610083,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chaoming","family":"Xie","sequence":"additional","affiliation":[{"name":"Key Laboratory of Advanced Technologies of Materials Ministry of Education, Institute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University , Chengdu 610031,","place":["China"]},{"name":"School of Materials Science and Engineering, Southwest Jiaotong University , Chengdu 610031,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7034-3215","authenticated-orcid":false,"given":"Jie","family":"Weng","sequence":"additional","affiliation":[{"name":"Key Laboratory of Advanced Technologies of Materials Ministry of Education, Institute of Biomedical Engineering, College of Medicine, Southwest Jiaotong University , Chengdu 610031,","place":["China"]},{"name":"School of Materials Science and Engineering, Southwest Jiaotong University , Chengdu 610031,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanan","family":"Jiang","sequence":"additional","affiliation":[{"name":"Obesity and Metabolism Medicine-Engineering Integration Laboratory, Department of General Surgery, The Affiliated Hospital of Southwest Jiaotong University, The Third People\u2019s Hospital of Chengdu , Chengdu 610031,","place":["China"]},{"name":"Medical Research Center, The Third People\u2019s Hospital of Chengdu, Affiliated Hospital of Southwest Jiaotong University, Chengdu 610014,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,6,12]]},"reference":[{"key":"2026071112213524000_rbag118-B1","doi-asserted-by":"crossref","first-page":"3655","DOI":"10.7150\/thno.85823","article-title":"LncRNAs associated with oxidative stress in diabetic wound healing: regulatory mechanisms and application prospects","volume":"13","author":"Yang","year":"2023","journal-title":"Theranostics"},{"key":"2026071112213524000_rbag118-B2","doi-asserted-by":"crossref","first-page":"e12719","DOI":"10.1002\/adma.202512719","article-title":"Hydrogel-based ROS-regulating strategy: reprogramming the oxidative stress imbalance in advanced diabetic wound repair","volume":"38","author":"Zhou","year":"2026","journal-title":"Adv Mater"},{"key":"2026071112213524000_rbag118-B3","doi-asserted-by":"crossref","first-page":"e2302391","DOI":"10.1002\/adhm.202302391","article-title":"Oxygen-generating hydrogels as oxygenation therapy for accelerated chronic wound healing","volume":"13","author":"Yang","year":"2024","journal-title":"Adv Healthc Mater"},{"key":"2026071112213524000_rbag118-B4","doi-asserted-by":"crossref","first-page":"2404461","DOI":"10.1002\/adfm.202404461","article-title":"Silk sericin-based ROS-responsive oxygen generating microneedle platform promotes angiogenesis and decreases inflammation for scarless diabetic wound healing","volume":"35","author":"Liu","year":"2025","journal-title":"Adv Funct Mater"},{"key":"2026071112213524000_rbag118-B5","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1111\/1574-6976.12026","article-title":"Antimicrobial strategies centered around reactive oxygen species\u2013bactericidal antibiotics, photodynamic therapy, and beyond","volume":"37","author":"Vatansever","year":"2013","journal-title":"FEMS Microbiol Rev"},{"key":"2026071112213524000_rbag118-B6","doi-asserted-by":"crossref","first-page":"eabj0153","DOI":"10.1126\/sciadv.abj0153","article-title":"Sustained oxygenation accelerates diabetic wound healing by promoting epithelialization and angiogenesis and decreasing inflammation","volume":"7","author":"Guan","year":"2021","journal-title":"Sci Adv"},{"key":"2026071112213524000_rbag118-B7","doi-asserted-by":"crossref","first-page":"e70014","DOI":"10.1111\/1753-0407.70014","article-title":"Overview of oxidative stress and inflammation in diabetes","volume":"16","author":"Weinberg Sibony","year":"2024","journal-title":"J Diabetes"},{"key":"2026071112213524000_rbag118-B8","first-page":"507","article-title":"Natural-origin bioadhesive hydrogel with dual antioxidative and immunoregulatory properties for enhanced angiogenesis and wound healing","volume":"53","author":"Li","year":"2025","journal-title":"Bioact Mater"},{"key":"2026071112213524000_rbag118-B9","doi-asserted-by":"crossref","first-page":"114594","DOI":"10.1016\/j.jconrel.2025.114594","article-title":"Inflammation-responsive DNA hydrogel integrating probiotic outer membrane vesicles for infection monitoring and precision therapy of diabetic wounds","volume":"391","author":"Tai","year":"2026","journal-title":"J Control Release"},{"key":"2026071112213524000_rbag118-B10","doi-asserted-by":"crossref","first-page":"102405","DOI":"10.1016\/j.mtbio.2025.102405","article-title":"Glucose-responsive nanozyme hydrogel for glycemic control and catalytic anti-infective therapy in diabetic wound healing","volume":"35","author":"Tai","year":"2025","journal-title":"Mater Today Bio"},{"key":"2026071112213524000_rbag118-B11","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/s41467-023-36133-8","article-title":"Hydrogel oxygen reservoirs increase functional integration of neural stem cell grafts by meeting metabolic demands","volume":"14","author":"Wang","year":"2023","journal-title":"Nat Commun"},{"key":"2026071112213524000_rbag118-B12","doi-asserted-by":"crossref","first-page":"101197","DOI":"10.1016\/j.mtbio.2024.101197","article-title":"Dual roles of photosynthetic hydrogel with sustained oxygen generation in promoting cell survival and eradicating anaerobic infection","volume":"28","author":"Kang","year":"2024","journal-title":"Mater Today Bio"},{"key":"2026071112213524000_rbag118-B13","doi-asserted-by":"crossref","first-page":"164422","DOI":"10.1016\/j.cej.2025.164422","article-title":"Self-oxygenating, anti-freezing, antioxidant, and UV-resistant lignin hydrogels for wound healing at high-altitude","volume":"517","author":"Xie","year":"2025","journal-title":"Chem Eng J"},{"key":"2026071112213524000_rbag118-B14","doi-asserted-by":"crossref","first-page":"e00362","DOI":"10.1002\/admt.202500362","article-title":"Oxygen-releasing hydrogels in biomedicine: present and future","volume":"10","author":"Cai","year":"2025","journal-title":"Adv Mater Technol"},{"key":"2026071112213524000_rbag118-B15","doi-asserted-by":"crossref","first-page":"rbaf134","DOI":"10.1093\/rb\/rbaf134","article-title":"Engineered bilayer hydrogel with spatiotemporal drug and oxygen delivery for diabetic wound microenvironment reprogramming","volume":"13","author":"Li","year":"2026","journal-title":"Regen Biomater"},{"key":"2026071112213524000_rbag118-B16","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1039\/D5TB02234G","article-title":"Polyphenol-enhanced extreme-environment adaptive hydrogels for high-altitude burn wound repair","volume":"14","author":"Jiang","year":"2026","journal-title":"J Mater Chem B"},{"key":"2026071112213524000_rbag118-B17","doi-asserted-by":"crossref","first-page":"1606134","DOI":"10.1002\/adma.201606134","article-title":"Metal\u2013organic framework (MOF)-based drug\/cargo delivery and cancer therapy","volume":"29","author":"Wu","year":"2017","journal-title":"Adv Mater"},{"key":"2026071112213524000_rbag118-B18","first-page":"103","article-title":"Metal\u2013organic framework nanocarriers for drug delivery in biomedical applications","volume":"12","author":"Sun","year":"2020","journal-title":"Nanomicro Lett"},{"key":"2026071112213524000_rbag118-B19","doi-asserted-by":"crossref","first-page":"46598","DOI":"10.1021\/acsami.3c06706","article-title":"A metal\u2013organic framework-incorporated hydrogel for delivery of immunomodulatory neobavaisoflavone to promote cartilage regeneration in osteoarthritis","volume":"15","author":"Jiang","year":"2023","journal-title":"ACS Appl Mater Interfaces"},{"key":"2026071112213524000_rbag118-B20","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.jconrel.2024.08.011","article-title":"ZIF-8-modified hydrogel sequentially delivers angiogenic and osteogenic growth factors to accelerate vascularized bone regeneration","volume":"374","author":"Niu","year":"2024","journal-title":"J Control Release"},{"key":"2026071112213524000_rbag118-B21","doi-asserted-by":"crossref","first-page":"111282","DOI":"10.1016\/j.mtcomm.2024.111282","article-title":"Bioactive hydrogel (ZIF-8@ CMC-PVA-SA) as dressing materials for wound healing applications","volume":"42","author":"Khan","year":"2025","journal-title":"Mater Today Commun"},{"key":"2026071112213524000_rbag118-B22","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1038\/nature17039","article-title":"Reparative inflammation takes charge of tissue regeneration","volume":"529","author":"Karin","year":"2016","journal-title":"Nature"},{"key":"2026071112213524000_rbag118-B23","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1038\/s41419-024-06947-5","article-title":"Systemic mechanisms of necrotic cell debris clearance","volume":"15","author":"Schuermans","year":"2024","journal-title":"Cell Death Dis"},{"key":"2026071112213524000_rbag118-B24","doi-asserted-by":"crossref","first-page":"e2300779","DOI":"10.1002\/adhm.202300779","article-title":"Reactive oxygen species-scavenging nanosystems in the treatment of diabetic wounds","volume":"12","author":"Xiong","year":"2023","journal-title":"Adv Healthc Mater"},{"key":"2026071112213524000_rbag118-B25","doi-asserted-by":"crossref","first-page":"163130","DOI":"10.1016\/j.cej.2025.163130","article-title":"2A-biohydrogels accelerate diabetic wound healing by promoting M2 macrophage polarization and functionalized mitochondrial transfer to endothelial cells","volume":"514","author":"Wang","year":"2025","journal-title":"Chem Eng J"},{"key":"2026071112213524000_rbag118-B26","doi-asserted-by":"crossref","first-page":"2412360","DOI":"10.1002\/advs.202412360","article-title":"Innovative hydrogel design: tailoring immunomodulation for optimal chronic wound recovery","volume":"12","author":"Lai","year":"2025","journal-title":"Adv Sci"},{"key":"2026071112213524000_rbag118-B27","doi-asserted-by":"crossref","first-page":"e08924","DOI":"10.1002\/advs.202508924","article-title":"Polyphenol-based functional materials: structural insights, composite strategies, and biomedical applications","volume":"12","author":"Xue","year":"2025","journal-title":"Adv Sci"},{"key":"2026071112213524000_rbag118-B28","first-page":"516","article-title":"Conductive polyphenol microneedles coupled with electroacupuncture to accelerate wound healing and alleviate depressive-like behaviors in diabetes","volume":"44","author":"Hou","year":"2025","journal-title":"Bioact Mater"},{"key":"2026071112213524000_rbag118-B29","doi-asserted-by":"crossref","first-page":"e2403734","DOI":"10.1002\/adhm.202403734","article-title":"Multifunctional adhesive hydrogels: from design to biomedical applications","volume":"14","author":"Tang","year":"2025","journal-title":"Adv Healthc Mater"},{"key":"2026071112213524000_rbag118-B30","doi-asserted-by":"crossref","first-page":"2745","DOI":"10.1021\/acsnano.2c11053","article-title":"Tuning water-resistant networks in mussel-inspired hydrogels for robust wet tissue and bioelectronic adhesion","volume":"17","author":"Hou","year":"2023","journal-title":"ACS Nano"},{"key":"2026071112213524000_rbag118-B31","doi-asserted-by":"crossref","first-page":"11432","DOI":"10.1021\/acs.chemrev.1c01042","article-title":"Metal ion-directed functional metal\u2013phenolic materials","volume":"122","author":"Geng","year":"2022","journal-title":"Chem Rev"},{"key":"2026071112213524000_rbag118-B32","doi-asserted-by":"crossref","first-page":"101182","DOI":"10.1016\/j.nantod.2021.101182","article-title":"Bioinspired adhesive and tumor microenvironment responsive nanoMOFs assembled 3D-printed scaffold for anti-tumor therapy and bone regeneration","volume":"39","author":"Jiang","year":"2021","journal-title":"Nano Today"},{"key":"2026071112213524000_rbag118-B33","doi-asserted-by":"crossref","first-page":"3605","DOI":"10.1039\/C9CS00849G","article-title":"Mussel-inspired hydrogels: from design principles to promising applications","volume":"49","author":"Zhang","year":"2020","journal-title":"Chem Soc Rev"},{"key":"2026071112213524000_rbag118-B34","doi-asserted-by":"crossref","first-page":"627","DOI":"10.1021\/accountsmr.3c00055","article-title":"Polyphenolic gelatin-based bioadhesives","volume":"4","author":"Montazerian","year":"2023","journal-title":"Acc Mater Res"},{"key":"2026071112213524000_rbag118-B35","doi-asserted-by":"crossref","first-page":"9482","DOI":"10.1080\/10408398.2022.2067830","article-title":"Chemical aspects of polyphenol\u2013protein interactions and their antibacterial activity","volume":"63","author":"Nassarawa","year":"2023","journal-title":"Crit Rev Food Sci Nutr"},{"key":"2026071112213524000_rbag118-B36","first-page":"1","article-title":"Insights into metallic Ag+, Cu2+, Zn2+ ions-induced bacteriolytic mechanism against S. aureus and E. coli","volume":"3","author":"Ishida","year":"2023","journal-title":"Catal Res"},{"key":"2026071112213524000_rbag118-B37","doi-asserted-by":"crossref","first-page":"2007356","DOI":"10.1002\/adma.202007356","article-title":"Polyphenol-containing nanoparticles: synthesis, properties, and therapeutic delivery","volume":"33","author":"Guo","year":"2021","journal-title":"Adv Mater"},{"key":"2026071112213524000_rbag118-B38","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1021\/jp3116319","article-title":"Free radical scavenging by natural polyphenols: atom versus electron transfer","volume":"117","author":"Di Meo","year":"2013","journal-title":"J Phys Chem A"},{"key":"2026071112213524000_rbag118-B39","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1039\/D5BM01548K","article-title":"Antioxidant nanozymes for periodontal bone regeneration: multifunctional mechanisms and therapeutic applications","volume":"14","author":"Liu","year":"2026","journal-title":"Biomater Sci"},{"key":"2026071112213524000_rbag118-B40","first-page":"213","article-title":"Polydopamine-mediated graphene oxide and nanohydroxyapatite-incorporated conductive scaffold with an immunomodulatory ability accelerates periodontal bone regeneration in diabetes","volume":"18","author":"Li","year":"2022","journal-title":"Bioact Mater"},{"key":"2026071112213524000_rbag118-B41","doi-asserted-by":"crossref","first-page":"e2400150","DOI":"10.1002\/adhm.202400150","article-title":"Inflammation-responsive hydrogel accelerates diabetic wound healing through immunoregulation and enhanced angiogenesis","volume":"14","author":"He","year":"2025","journal-title":"Adv Healthc Mater"},{"key":"2026071112213524000_rbag118-B42","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1038\/s41413-025-00471-8","article-title":"Biomaterial-mediated macrophage polarization remodeling and sequential regulation: a potential strategy in bone infections treatment","volume":"13","author":"Shi","year":"2025","journal-title":"Bone Res"},{"key":"2026071112213524000_rbag118-B43","doi-asserted-by":"crossref","first-page":"20417314241253290","DOI":"10.1177\/20417314241253290","article-title":"Microenvironmental dynamics of diabetic wounds and insights for hydrogel-based therapeutics","volume":"15","author":"Zhao","year":"2024","journal-title":"J Tissue Eng"},{"key":"2026071112213524000_rbag118-B44","doi-asserted-by":"crossref","first-page":"8662","DOI":"10.1021\/acsnano.2c00662","article-title":"Infant skin friendly adhesive hydrogel patch activated at body temperature for bioelectronics securing and diabetic wound healing","volume":"16","author":"Jiang","year":"2022","journal-title":"ACS Nano"},{"key":"2026071112213524000_rbag118-B45","doi-asserted-by":"crossref","first-page":"121401","DOI":"10.1016\/j.biomaterials.2022.121401","article-title":"Nano-oxygenated hydrogels for locally and permeably hypoxia relieving to heal chronic wounds","volume":"282","author":"Yang","year":"2022","journal-title":"Biomaterials"},{"key":"2026071112213524000_rbag118-B46","doi-asserted-by":"crossref","first-page":"2404538","DOI":"10.1002\/smll.202404538","article-title":"Oxygen-propelled dual-modular microneedles with dopamine-enhanced RNA delivery for regulating each stage of diabetic wounds","volume":"20","author":"Ran","year":"2024","journal-title":"Small"},{"key":"2026071112213524000_rbag118-B47","doi-asserted-by":"crossref","first-page":"162231","DOI":"10.1016\/j.cej.2025.162231","article-title":"Rapid hemostatic and bio-adhesive polyphenol powders with physiological extreme condition-tolerance for noncompressible wound healing","volume":"511","author":"Zheng","year":"2025","journal-title":"Chem Eng J"},{"key":"2026071112213524000_rbag118-B48","first-page":"330","article-title":"Versatile dopamine-functionalized hyaluronic acid-recombinant human collagen hydrogel promoting diabetic wound healing via inflammation control and vascularization tissue regeneration","volume":"35","author":"Wang","year":"2024","journal-title":"Bioact Mater"}],"container-title":["Regenerative Biomaterials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/rb\/advance-article-pdf\/doi\/10.1093\/rb\/rbag118\/68520418\/rbag118.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/rb\/article-pdf\/doi\/10.1093\/rb\/rbag118\/68520418\/rbag118.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/rb\/article-pdf\/doi\/10.1093\/rb\/rbag118\/68520418\/rbag118.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T16:22:02Z","timestamp":1783786922000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/rb\/article\/doi\/10.1093\/rb\/rbag118\/8707349"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":48,"URL":"https:\/\/doi.org\/10.1093\/rb\/rbag118","relation":{},"ISSN":["2056-3418","2056-3426"],"issn-type":[{"value":"2056-3418","type":"print"},{"value":"2056-3426","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026]]},"published":{"date-parts":[[2026]]},"article-number":"rbag118"}}