{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T22:05:38Z","timestamp":1783980338099,"version":"3.55.0"},"reference-count":56,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T00:00:00Z","timestamp":1782345600000},"content-version":"vor","delay-in-days":175,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Health Research Program of Anhui","award":["AHWJ2023A20332"],"award-info":[{"award-number":["AHWJ2023A20332"]}]},{"name":"Scientific Research Project of Anhui Provincial Department of Education","award":["2025AHGXZK31300"],"award-info":[{"award-number":["2025AHGXZK31300"]}]},{"name":"Natural Science Research Project of Anhui Educational Committee","award":["2024AH050661"],"award-info":[{"award-number":["2024AH050661"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,22]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Gingival recession exposes the roots, leads to dentin hypersensitivity, and heightens the progression of periodontitis, and poses a threat to oral health and appearance. Conventional treatment uses autogenous palatal grafts, requiring a second surgical site and adding patient discomfort. To overcome autograft limitations, this study developed a hydrogel scaffold as a potential biomaterial candidate for gingival soft tissue augmentation. We developed a multifunctional HA\/SF hydrogel scaffold by incorporating EGCG and the antimicrobial peptide LL-37. It exhibits antibacterial, anti-inflammatory, antioxidant and pro-angiogenic activities. Its 3D network mimics the native extracellular matrix (ECM), enables minimally invasive delivery and conforms to irregular root surfaces. In vitro, it inhibits bacterial growth and adhesion, and significantly reduces pro-inflammatory cytokine expression in LPS-stimulated macrophages. Animal experiments in rats showed that the HA\/SF\/EGCG\/LL37 scaffold significantly increased neovascular density, improved collagen fiber organization and enhanced anti-inflammatory and antioxidant effects versus controls. By balancing oral microbiota, dampening excessive inflammation and reducing oxidative stress, it represents a promising biologically active strategy that may facilitate gingival soft tissue regeneration.<\/jats:p>","DOI":"10.1093\/rb\/rbag131","type":"journal-article","created":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T11:40:19Z","timestamp":1782214819000},"source":"Crossref","is-referenced-by-count":0,"title":["A degradable hydrogel scaffold incorporating the LL-37 for gingival soft tissue regeneration"],"prefix":"10.1093","volume":"13","author":[{"given":"Jing","family":"Mao","sequence":"first","affiliation":[{"name":"College & Hospital of Stomatology, Anhui Medical University, Anhui Provincial Key Laboratory of Oral Diseases Research , Hefei 230032,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangyang","family":"Li","sequence":"additional","affiliation":[{"name":"College & Hospital of Stomatology, Anhui Medical University, Anhui Provincial Key Laboratory of Oral Diseases Research , Hefei 230032,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kainan","family":"Liao","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology, Anhui Medical University (AHMU) , Hefei 230032,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Longge","family":"Liu","sequence":"additional","affiliation":[{"name":"College & Hospital of Stomatology, Anhui Medical University, Anhui Provincial Key Laboratory of Oral Diseases Research , Hefei 230032,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huimin","family":"Zheng","sequence":"additional","affiliation":[{"name":"College & Hospital of Stomatology, Anhui Medical University, Anhui Provincial Key Laboratory of Oral Diseases Research , Hefei 230032,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunong","family":"Cui","sequence":"additional","affiliation":[{"name":"College & Hospital of Stomatology, Anhui Medical University, Anhui Provincial Key Laboratory of Oral Diseases Research , Hefei 230032,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zixuan","family":"Guo","sequence":"additional","affiliation":[{"name":"College & Hospital of Stomatology, Anhui Medical University, Anhui Provincial Key Laboratory of Oral Diseases Research , Hefei 230032,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kexin","family":"Song","sequence":"additional","affiliation":[{"name":"College & Hospital of Stomatology, Anhui Medical University, Anhui Provincial Key Laboratory of Oral Diseases Research , Hefei 230032,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junjie","family":"Zhao","sequence":"additional","affiliation":[{"name":"College & Hospital of Stomatology, Anhui Medical University, Anhui Provincial Key Laboratory of Oral Diseases Research , Hefei 230032,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leping","family":"Wu","sequence":"additional","affiliation":[{"name":"College & Hospital of Stomatology, Anhui Medical University, Anhui Provincial Key Laboratory of Oral Diseases Research , Hefei 230032,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weibo","family":"Zhang","sequence":"additional","affiliation":[{"name":"College & Hospital of Stomatology, Anhui Medical University, Anhui Provincial Key Laboratory of Oral Diseases Research , Hefei 230032,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jialong","family":"Chen","sequence":"additional","affiliation":[{"name":"College & Hospital of Stomatology, Anhui Medical University, Anhui Provincial Key Laboratory of Oral Diseases Research , Hefei 230032,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Li","sequence":"additional","affiliation":[{"name":"College & Hospital of Stomatology, Anhui Medical University, Anhui Provincial Key Laboratory of Oral Diseases Research , Hefei 230032,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,6,25]]},"reference":[{"key":"2026071317460957400_rbag131-B1","doi-asserted-by":"crossref","first-page":"220","DOI":"10.14219\/jada.archive.2003.0137","article-title":"The etiology and prevalence of gingival recession","volume":"134","author":"Kassab","year":"2003","journal-title":"J Am Dent Assoc"},{"key":"2026071317460957400_rbag131-B2","doi-asserted-by":"crossref","first-page":"105645","DOI":"10.1016\/j.jdent.2025.105645","article-title":"Systematic review and meta-analysis on prevalence and risk factors for gingival recession","volume":"155","author":"Marschner","year":"2025","journal-title":"J Dent"},{"key":"2026071317460957400_rbag131-B3","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1111\/idj.12617","article-title":"Treatment of gingival recession: when and how?","volume":"71","author":"Imber","year":"2021","journal-title":"Int Dent J"},{"key":"2026071317460957400_rbag131-B4","doi-asserted-by":"crossref","first-page":"S36","DOI":"10.1111\/jcpe.12219","article-title":"Clinical efficacy of periodontal plastic surgery procedures: consensus report of Group 2 of the 10th European Workshop on Periodontology","volume":"41","author":"Tonetti","year":"2014","journal-title":"J Clin Periodontol"},{"key":"2026071317460957400_rbag131-B5","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1038\/s41579-018-0089-x","article-title":"The oral microbiota: dynamic communities and host interactions","volume":"16","author":"Lamont","year":"2018","journal-title":"Nat Rev Microbiol"},{"key":"2026071317460957400_rbag131-B6","doi-asserted-by":"crossref","first-page":"4357","DOI":"10.1021\/acs.biomac.2c00815","article-title":"Hemocompatibility multi-in-one hydrogel coating with ROS-triggered inflammation suppression and anti-infection properties for blood-contacting device","volume":"23","author":"Wei","year":"2022","journal-title":"Biomacromolecules"},{"key":"2026071317460957400_rbag131-B7","first-page":"3328","article-title":"The recent advances in scaffolds for integrated periodontal regeneration","volume":"6","author":"Woo","year":"2021","journal-title":"Bioact Mater"},{"key":"2026071317460957400_rbag131-B8","doi-asserted-by":"crossref","first-page":"38947","DOI":"10.1021\/acsami.1c05167","article-title":"Dressing blood-contacting materials by a stable hydrogel coating with embedded antimicrobial peptides for robust antibacterial and antithrombus properties","volume":"13","author":"Liu","year":"2021","journal-title":"ACS Appl Mater Interfaces"},{"key":"2026071317460957400_rbag131-B9","doi-asserted-by":"crossref","DOI":"10.3390\/jfb15080233","article-title":"Biomaterial scaffolds for periodontal tissue engineering","volume":"15","author":"Chen","year":"2024","journal-title":"J Funct Biomater"},{"key":"2026071317460957400_rbag131-B10","doi-asserted-by":"crossref","first-page":"134932","DOI":"10.1016\/j.ijbiomac.2024.134932","article-title":"Arginine-loaded globular BSAMA\/fibrous GelMA biohybrid cryogels with multifunctional features and enhanced healing for soft gingival tissue regeneration","volume":"278","author":"Hu","year":"2024","journal-title":"Int J Biol Macromol"},{"key":"2026071317460957400_rbag131-B11","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1111\/jre.12333","article-title":"Xenogeneic collagen matrix for periodontal plastic surgery procedures: a systematic review and meta-analysis","volume":"51","author":"Atieh","year":"2016","journal-title":"J Periodontal Res"},{"key":"2026071317460957400_rbag131-B12","volume-title":"Recent Advances in Biopolymers","author":"Oluwafemi","year":"2016"},{"key":"2026071317460957400_rbag131-B13","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21145043","article-title":"How thick is the oral mucosa around implants after augmentation with different materials: a systematic review of the effectiveness of substitute matrices in comparison to connective tissue grafts","volume":"21","author":"Lissek","year":"2020","journal-title":"Int J Mol Sci"},{"key":"2026071317460957400_rbag131-B14","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.bbrc.2021.08.026","article-title":"Regulating the mechanics of silk fibroin scaffolds promotes wound vascularization","volume":"574","author":"Guo","year":"2021","journal-title":"Biochem Biophys Res Commun"},{"key":"2026071317460957400_rbag131-B15","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.addr.2012.09.043","article-title":"Silk fibroin biomaterials for tissue regenerations","volume":"65","author":"Kundu","year":"2013","journal-title":"Adv Drug Deliv Rev"},{"key":"2026071317460957400_rbag131-B16","doi-asserted-by":"crossref","first-page":"2736","DOI":"10.1002\/jbm.a.36777","article-title":"Three-dimensional cryogels for biomedical applications","volume":"107","author":"Razavi","year":"2019","journal-title":"J Biomed Mater Res A"},{"key":"2026071317460957400_rbag131-B17","doi-asserted-by":"crossref","first-page":"858","DOI":"10.3390\/ijms18040858","article-title":"Silk fibroin-alginate-hydroxyapatite composite particles in bone tissue engineering applications in vivo","volume":"18","author":"Jo","year":"2017","journal-title":"Int J Mol Sci"},{"key":"2026071317460957400_rbag131-B18","doi-asserted-by":"crossref","first-page":"126104","DOI":"10.1016\/j.ijbiomac.2023.126104","article-title":"Berberine oleanolic acid complex salt grafted hyaluronic acid\/silk fibroin (BOA-g-HA\/SF) composite scaffold promotes cartilage tissue regeneration under IL-1\u03b2 caused stress","volume":"250","author":"Li","year":"2023","journal-title":"Int J Biol Macromol"},{"key":"2026071317460957400_rbag131-B19","doi-asserted-by":"crossref","first-page":"3767","DOI":"10.1016\/j.apsb.2025.04.020","article-title":"A high clinically translatable strategy to anti-aging using hyaluronic acid and silk fibroin co-crosslinked hydrogels as dermal regenerative fillers","volume":"15","author":"Cheng","year":"2025","journal-title":"Acta Pharm Sin B"},{"key":"2026071317460957400_rbag131-B20","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.actbio.2023.05.044","article-title":"A hyaluronic acid\/silk fibroin\/poly-dopamine-coated biomimetic hydrogel scaffold with incorporated neurotrophin-3 for spinal cord injury repair","volume":"167","author":"Sha","year":"2023","journal-title":"Acta Biomater"},{"key":"2026071317460957400_rbag131-B21","doi-asserted-by":"crossref","first-page":"108139","DOI":"10.1016\/j.compositesb.2020.108139","article-title":"Preparation of a chitosan\/carboxymethyl chitosan\/AgNPs polyelectrolyte composite physical hydrogel with self-healing ability, antibacterial properties, and good biosafety simultaneously, and its application as a wound dressing","volume":"197","author":"Yang","year":"2020","journal-title":"Compos Part B: Eng"},{"key":"2026071317460957400_rbag131-B22","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1111\/prd.12028","article-title":"Defensins and LL-37: a review of function in the gingival epithelium","volume":"63","author":"Greer","year":"2013","journal-title":"Periodontol 2000"},{"key":"2026071317460957400_rbag131-B23","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1016\/S0966-842X(00)01823-0","article-title":"The role of cationic antimicrobial peptides in innate host defences","volume":"8","author":"Hancock","year":"2000","journal-title":"Trends Microbiol"},{"key":"2026071317460957400_rbag131-B24","doi-asserted-by":"crossref","first-page":"25","DOI":"10.2174\/1568026615666150703121700","article-title":"Antimicrobial peptide structure and mechanism of action: a focus on the role of membrane structure","volume":"16","author":"Lee","year":"2016","journal-title":"Curr Top Med Chem"},{"key":"2026071317460957400_rbag131-B25","doi-asserted-by":"crossref","first-page":"320","DOI":"10.3390\/biom14030320","article-title":"LL-37: structures, antimicrobial activity, and influence on amyloid-related diseases","volume":"14","author":"Bhattacharjya","year":"2024","journal-title":"Biomolecules"},{"key":"2026071317460957400_rbag131-B26","doi-asserted-by":"crossref","first-page":"650","DOI":"10.3390\/antibiotics10060650","article-title":"The potential of human peptide LL-37 as an antimicrobial and anti-biofilm agent","volume":"10","author":"Ridyard","year":"2021","journal-title":"Antibiotics (Basel)"},{"key":"2026071317460957400_rbag131-B27","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/s11274-023-03545-z","article-title":"Antibiofilm properties of cathelicidin LL-37: an in-depth review","volume":"39","author":"Memariani","year":"2023","journal-title":"World J Microbiol Biotechnol"},{"key":"2026071317460957400_rbag131-B28","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.3390\/biomedicines10051086","article-title":"Cathelicidin LL-37 in health and diseases of the oral cavity","volume":"10","author":"Tokajuk","year":"2022","journal-title":"Biomedicines"},{"key":"2026071317460957400_rbag131-B29","doi-asserted-by":"crossref","first-page":"7357162","DOI":"10.1155\/2018\/7357162","article-title":"Cathelicidin LL-37 affects surface and intracellular toll-like receptor expression in tissue mast cells","volume":"2018","author":"Agier","year":"2018","journal-title":"J Immunol Res"},{"key":"2026071317460957400_rbag131-B30","doi-asserted-by":"crossref","first-page":"2206936","DOI":"10.1002\/adfm.202206936","article-title":"Nanofiber aerogels with precision macrochannels and LL-37-mimic peptides synergistically promote diabetic wound healing","volume":"33","author":"John","year":"2023","journal-title":"Adv Funct Mater"},{"key":"2026071317460957400_rbag131-B31","doi-asserted-by":"crossref","first-page":"8153","DOI":"10.1039\/D1BM01034D","article-title":"Antimicrobial and pro-angiogenic properties of soluble and nanoparticle-immobilized LL37 peptides","volume":"9","author":"Comune","year":"2021","journal-title":"Biomater Sci"},{"key":"2026071317460957400_rbag131-B32","doi-asserted-by":"crossref","first-page":"rbaa036","DOI":"10.1093\/rb\/rbaa036","article-title":"Regeneration of critical-sized defects, in a goat model, using a dextrin-based hydrogel associated with granular synthetic bone substitute","volume":"8","author":"Pereira","year":"2021","journal-title":"Regen Biomater"},{"key":"2026071317460957400_rbag131-B33","first-page":"1533","article-title":"Regulation of LL-37 in bone and periodontium regeneration","volume":"12","author":"Chinipardaz","year":"2022","journal-title":"Life (Basel)"},{"key":"2026071317460957400_rbag131-B34","doi-asserted-by":"crossref","first-page":"171320","DOI":"10.1016\/j.peptides.2024.171320","article-title":"Host defense peptides at the crossroad of endothelial cell physiology: insight into mechanistic and pharmacological implications","volume":"182","author":"Garg","year":"2024","journal-title":"Peptides"},{"key":"2026071317460957400_rbag131-B35","doi-asserted-by":"crossref","first-page":"1587351","DOI":"10.3389\/fphar.2025.1587351","article-title":"LL37 promotes angiogenesis: a potential therapeutic strategy for lower limb ischemic diseases","volume":"16","author":"Yang","year":"2025","journal-title":"Front Pharmacol"},{"key":"2026071317460957400_rbag131-B36","doi-asserted-by":"crossref","first-page":"e10619","DOI":"10.1002\/btm2.10619","article-title":"Self-assembly of PEG-PPS polymers and LL-37 peptide nanomicelles improves the oxidative microenvironment and promotes angiogenesis to facilitate chronic wound healing","volume":"9","author":"Shi","year":"2024","journal-title":"Bioeng Transl Med"},{"key":"2026071317460957400_rbag131-B37","doi-asserted-by":"crossref","first-page":"27614","DOI":"10.1074\/jbc.M114.582973","article-title":"LL-37 peptide enhancement of signal transduction by toll-like receptor 3 is regulated by pH: identification of a peptide antagonist of LL-37","volume":"289","author":"Singh","year":"2014","journal-title":"J Biol Chem"},{"key":"2026071317460957400_rbag131-B38","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1080\/13543776.2016.1203419","article-title":"Therapeutic effects of EGCG: a patent review","volume":"26","author":"Chakrawarti","year":"2016","journal-title":"Expert Opin Ther Pat"},{"key":"2026071317460957400_rbag131-B39","doi-asserted-by":"crossref","first-page":"654","DOI":"10.3390\/molecules30030654","article-title":"Epigallocatechin gallate (EGCG): pharmacological properties, biological activities and therapeutic potential","volume":"30","author":"Capasso","year":"2025","journal-title":"Molecules"},{"key":"2026071317460957400_rbag131-B40","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1631\/bdm.2400114","article-title":"Enhancing angiogenesis and osseointegration through a double gyroid Ti6Al4V scaffold with triply periodic minimal surface","volume":"8","author":"Liu","year":"2025","journal-title":"Bio-Des Manuf"},{"key":"2026071317460957400_rbag131-B41","doi-asserted-by":"crossref","first-page":"e1906024","DOI":"10.1002\/adma.201906024","article-title":"A metal-polyphenol-coordinated nanomedicine for synergistic cascade cancer chemotherapy and chemodynamic therapy","volume":"32","author":"Ren","year":"2020","journal-title":"Adv Mater"},{"key":"2026071317460957400_rbag131-B42","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1038\/s41578-020-0209-x","article-title":"Engineered biomaterials for in situ tissue regeneration","volume":"5","author":"Gaharwar","year":"2020","journal-title":"Nat Rev Mater"},{"key":"2026071317460957400_rbag131-B43","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.jcis.2020.09.105","article-title":"A novel hydrogel with self-healing property and bactericidal activity","volume":"584","author":"Wu","year":"2021","journal-title":"J Colloid Interface Sci"},{"key":"2026071317460957400_rbag131-B44","doi-asserted-by":"crossref","first-page":"15748","DOI":"10.3390\/ijms242115748","article-title":"From static to dynamic: smart materials pioneering additive manufacturing in regenerative medicine","volume":"24","author":"Kantaros","year":"2023","journal-title":"Int J Mol Sci"},{"key":"2026071317460957400_rbag131-B45","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/j.polymdegradstab.2019.04.006","article-title":"Water-stable silk fibroin nerve conduits with tunable degradation prepared by a mild freezing-induced assembly","volume":"164","author":"Li","year":"2019","journal-title":"Polym Degrad Stab"},{"key":"2026071317460957400_rbag131-B46","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.copbio.2017.05.005","article-title":"Engineering cell fitness: lessons for regenerative medicine","volume":"47","author":"Shakiba","year":"2017","journal-title":"Curr Opin Biotechnol"},{"key":"2026071317460957400_rbag131-B47","doi-asserted-by":"crossref","first-page":"1665","DOI":"10.1172\/JCI17545","article-title":"An angiogenic role for the human peptide antibiotic LL-37\/hCAP-18","volume":"111","author":"Koczulla","year":"2003","journal-title":"J Clin Invest"},{"key":"2026071317460957400_rbag131-B48","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1111\/j.1600-0765.2012.01524.x","article-title":"Antimicrobial peptide LL37 promotes vascular endothelial growth factor-A expression in human periodontal ligament cells","volume":"48","author":"Kittaka","year":"2013","journal-title":"J Periodontal Res"},{"key":"2026071317460957400_rbag131-B49","doi-asserted-by":"crossref","first-page":"107529","DOI":"10.1016\/j.phrs.2024.107529","article-title":"Cathelicidin peptide LL-37: a multifunctional peptide involved in heart disease","volume":"210","author":"Miao","year":"2024","journal-title":"Pharmacol Res"},{"key":"2026071317460957400_rbag131-B50","article-title":"Anti-oxidation functions of tea polyphenols and their mechanisms","author":"Lei","year":"2017","journal-title":"Chin J Anim Nutr"},{"key":"2026071317460957400_rbag131-B51","doi-asserted-by":"crossref","first-page":"31474","DOI":"10.1038\/s41598-024-82938-y","article-title":"EGCG activates Keap1\/P62\/Nrf2 pathway, inhibits iron deposition and apoptosis in rats with cerebral hemorrhage","volume":"14","author":"Hao","year":"2024","journal-title":"Sci Rep"},{"key":"2026071317460957400_rbag131-B52","doi-asserted-by":"crossref","first-page":"7981","DOI":"10.1021\/acsnano.4c15227","article-title":"Bioactive Zn\u2013V\u2013Si\u2013Ca glass nanoparticle hydrogel microneedles with antimicrobial and antioxidant properties for bone regeneration in diabetic periodontitis","volume":"19","author":"Li","year":"2025","journal-title":"ACS Nano"},{"key":"2026071317460957400_rbag131-B53","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1111\/j.1600-0757.1996.tb00178.x","article-title":"The development of periodontal plastic surgery","volume":"11","author":"Miller","year":"1996","journal-title":"Periodontol 2000"},{"key":"2026071317460957400_rbag131-B54","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1111\/prd.12287","article-title":"Soft tissue-related complications and management around dental implants","volume":"81","author":"Chackartchi","year":"2019","journal-title":"Periodontol 2000"},{"key":"2026071317460957400_rbag131-B55","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1111\/jcpe.13394","article-title":"Keratinized tissue gain after free gingival graft augmentation procedures around teeth and dental implants: a prospective observational study","volume":"48","author":"Golmayo","year":"2021","journal-title":"J Clin Periodontol"},{"key":"2026071317460957400_rbag131-B56","doi-asserted-by":"crossref","DOI":"10.1002\/bmm2.12069","article-title":"Regulatory mechanisms and regeneration strategies of the soft\u2013hard tissue interface in the human periodontium","volume":"2","author":"Dang","year":"2024","journal-title":"BMEmat"}],"container-title":["Regenerative Biomaterials"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/rb\/advance-article-pdf\/doi\/10.1093\/rb\/rbag131\/68612446\/rbag131.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/rb\/article-pdf\/doi\/10.1093\/rb\/rbag131\/68612446\/rbag131.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/rb\/article-pdf\/doi\/10.1093\/rb\/rbag131\/68612446\/rbag131.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T21:46:24Z","timestamp":1783979184000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/rb\/article\/doi\/10.1093\/rb\/rbag131\/8716251"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":56,"URL":"https:\/\/doi.org\/10.1093\/rb\/rbag131","relation":{},"ISSN":["2056-3418","2056-3426"],"issn-type":[{"value":"2056-3418","type":"print"},{"value":"2056-3426","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026]]},"published":{"date-parts":[[2026]]},"article-number":"rbag131"}}