{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T10:05:34Z","timestamp":1780481134194,"version":"3.54.1"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The preferred treatment for locally advanced cervical cancer, classified as IB2-IVA in Federation of Gynaecology and Obstetrics staging, has been external radiotherapy to the pelvis, cervix, uterus, and parametrium, combined with an additional dose of intracavitary brachytherapy (BRT). Occasionally, the treatment team may encounter patients who refuse treatment, large cervical tumours with extensive lateral parametrial involvement that are inaccessible for interstitial implant, or medical conditions that completely prevent the use of BRT. These challenging situations call for an alternative approach to deliver the intended therapeutic dose without adhering strictly to the belief that BRT is indispensable. This study aims to evaluate the feasibility of volumetric modulated arc therapy (VMAT) as a substitute for BRT by comparing 3D BRT and VMAT-generated stereotactic body radiotherapy (SBRT) plans, particularly for patients with advanced cervical cancer and large tumour sizes. Based on dosimetric data, SBRT may be a viable alternative to BRT if necessary.<\/jats:p>","DOI":"10.1093\/rpd\/ncag005","type":"journal-article","created":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T12:40:40Z","timestamp":1767876040000},"page":"720-725","source":"Crossref","is-referenced-by-count":0,"title":["Can volumetric arc therapy be an alternative to brachytherapy in advanced cervical cancer radiotherapy?"],"prefix":"10.1093","volume":"202","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6067-2552","authenticated-orcid":false,"given":"Yilmaz","family":"BILEK","sequence":"first","affiliation":[{"name":"Radiation Oncology, Medicine Faculty , Akdeniz University, Antalya, Turkiye"},{"name":"Physics Department, Science Faculty , Akdeniz University, Antalya, Turkiye"},{"name":"Radiotherapy, Vocational School of Health Sciences , Akdeniz University, Antalya, Turkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9788-699X","authenticated-orcid":false,"given":"Ismail","family":"Hakki SARPUN","sequence":"additional","affiliation":[{"name":"Radiation Oncology, Medicine Faculty, Akdeniz University , Antalya, Turkiye"},{"name":"Physics Department, Science Faculty, Akdeniz University , Antalya, Turkiye"},{"name":"Nuclear Sciences Research and Application Centre, Akdeniz University , Antalya, Turkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timur","family":"KOCA","sequence":"additional","affiliation":[{"name":"Radiation Oncology, Medicine Faculty, Akdeniz University , Antalya, Turkiye"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,6,3]]},"reference":[{"key":"2026060305104262900_ref1","doi-asserted-by":"publisher","first-page":"298","DOI":"10.1016\/j.canrad.2021.11.009","article-title":"Radiotherapy of cervical cancer","volume":"26","author":"Chargari","year":"2022","journal-title":"Cancer\/Radiotherapie"},{"key":"2026060305104262900_ref2","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1016\/S0140-6736(07)61416-0","article-title":"Human papillomavirus and cervical cancer","volume":"370","author":"Schiffman","year":"2007","journal-title":"Lancet"},{"key":"2026060305104262900_ref3","doi-asserted-by":"publisher","first-page":"772","DOI":"10.1016\/j.ijrobp.2007.10.066","article-title":"External beam boost for cancer of the cervix uteri when intracavitary therapy cannot be performed","volume":"71","author":"Barraclough","year":"2008","journal-title":"Int J Radiation Biol Phys"},{"key":"2026060305104262900_ref4","first-page":"191","article-title":"Radiochemoteraphy for patients with locally advanced cervical cancer: early results","volume":"24","author":"Ozsaran","year":"2003","journal-title":"Eur J Gynaecol Oncol"},{"key":"2026060305104262900_ref5","doi-asserted-by":"publisher","first-page":"207","DOI":"10.21037\/atm.2017.03.102","article-title":"External beam techniques to boost cervical cancer when brachytherapy is not an option-theories and applications","volume":"5","author":"Mahmoud","year":"2017","journal-title":"Ann Transl Med"},{"key":"2026060305104262900_ref6","doi-asserted-by":"publisher","first-page":"53","DOI":"10.21873\/cdp.10008","article-title":"Stereotactic body radiation therapy boost in patients with cervical cancer ineligible for brachytherapy","volume":"1","author":"Facondo","year":"2021","journal-title":"Cancer Diagnosis and Prognosis"},{"key":"2026060305104262900_ref7","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1016\/j.brachy.2011.07.002","article-title":"American brachytherapy society consensus guidelines for locally advanced carcinoma of the cervix. 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