{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T10:19:20Z","timestamp":1783333160312,"version":"3.54.6"},"reference-count":40,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T00:00:00Z","timestamp":1774224000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>This study investigated the use of JavaScript (JS) to develop and test an open-access method, provided as a research resource, for predicting the decay and cumulative activity of iodine-131 (131I). A client-side JS engine was implemented to simulate decay using mono-exponential and piecewise multi-segmented models. Built-in JS functions were used to perform logarithmic and exponential operations. The tool\u2019s performance was validated against ion-chamber measurements from a thyroid phantom containing a pre-calibrated 131I capsule; moreover, measurement reliability was assessed. The phantom test showed a mean absolute error of 0.010\u00a0\u03bcSv\/h for the mono-exponential model and 0.008\u00a0\u03bcSv\/h for the multi-segmented model. The intraclass correlation coefficient (ICC) demonstrated excellent inter-observer agreement (ICC range: 0.998\u20130.999), while the mean intra-observer difference was 0.3% (SD\u00a0=\u00a00.2%; range: 0.1%\u20130.6%). By quantifying instrument-related error in advance, future studies may more confidently isolate biological variability, thereby supporting the robustness of patient-level interpretation and dose-prediction models.<\/jats:p>","DOI":"10.1093\/rpd\/ncag024","type":"journal-article","created":{"date-parts":[[2026,3,23]],"date-time":"2026-03-23T15:57:58Z","timestamp":1774281478000},"page":"892-903","source":"Crossref","is-referenced-by-count":0,"title":["A JavaScript-based computational method for predicting decay activity of 131I: development, benchmark- and phantom-based assessment of an open-access research tool"],"prefix":"10.1093","volume":"202","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5603-4689","authenticated-orcid":false,"given":"Ludovico M","family":"Garau","sequence":"first","affiliation":[{"name":"Department of Nuclear Medicine, Santa Maria della Misericordia University Hospital , Piazzale Santa Maria della Misericordia, 15, 33100, Udine ,","place":["Italy"]},{"name":"Department of Electrical, Computer and Biomedical Engineering, Pavia University , Via A. Ferrata, 5, 27100 Pavia ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veronica","family":"Rosso","sequence":"additional","affiliation":[{"name":"Department of Medical Physics, Santa Maria della Misericordia University Hospital , Piazzale Santa Maria della Misericordia, 15, 33100, Udine ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Livio","family":"Bastianutti","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Santa Maria della Misericordia University Hospital , Piazzale Santa Maria della Misericordia, 15, 33100, Udine ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefano","family":"Schiattarella","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Santa Maria della Misericordia University Hospital , Piazzale Santa Maria della Misericordia, 15, 33100, Udine ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Di Gregorio","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Santa Maria della Misericordia University Hospital , Piazzale Santa Maria della Misericordia, 15, 33100, Udine ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,3,23]]},"reference":[{"key":"2026070606011655000_ref1","doi-asserted-by":"publisher","first-page":"209","DOI":"10.3322\/caac.21660","article-title":"Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J Clin"},{"key":"2026070606011655000_ref2","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1177\/10507256251363120","article-title":"2025 American Thyroid Association management guidelines for adult patients 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