{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T13:34:02Z","timestamp":1793712842423,"version":"4.6.1"},"reference-count":28,"publisher":"Oxford University Press (OUP)","issue":"18","license":[{"start":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T00:00:00Z","timestamp":1785974400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,11,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Background: Positron Emission Tomography\/Computed Tomography (PET\/CT) is a crucial imaging modality widely used for diagnosing and staging various cancers. Although patient weight is known to influence radiation dose, there is limited research on optimizing PET\/CT protocols based on weight categories to minimize unnecessary exposure. Objectives: This study evaluates the effective dose for common PET\/CT scans at Penang Hospital, with a particular focus on the influence of patient weight on both PET and CT dose components. Additionally, the study assesses whether weight-based dose protocols can contribute to dose optimization. Methods: This retrospective study analyzed 1439 PET\/CT scans performed at Penang Hospital. The effective dose was calculated using International Commission on Radiological Protection (ICRP) 103, 106, and 128 dose coefficients. Conversion factors used were 0.019\u00a0mSv\/MBq for 18F-FDG, 0.0199\u00a0mSv\/MBq for 68Ga-PSMA, and 0.021\u00a0mSv\/MBq for 68Ga-DOTATATE. The CT dose component was estimated using the dose-length product (DLP) with an empirical conversion factor (k\u00a0=\u00a00.015\u00a0mSv\u00b7mGy\u22121\u00b7cm\u22121) for whole-body CT. Results: The total effective dose for 18F-FDG (head-to-thigh and head-to-feet) scans was 12.34 and 16.38\u00a0mSv, respectively. For 68Ga-PSMA and 68Ga-DOTATATE scans, the total effective dose was 11.55 and 12.00\u00a0mSv, respectively. A statistically significant increase in dose was observed in heavier patients due to increased administered activity and CT parameters (P\u00a0&amp;lt;\u00a0.05). Weight had a smaller impact on PET dose in 68Ga-PSMA and 68Ga-DOTATATE compared to 18F-FDG. Conclusion: Patient weight significantly influences the total effective dose in PET\/CT examinations. These findings highlight the importance of considering patient-specific factors when evaluating radiation dose in clinical practice.<\/jats:p>","DOI":"10.1093\/rpd\/ncag078","type":"journal-article","created":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T13:19:55Z","timestamp":1783084795000},"page":"1477-1485","source":"Crossref","is-referenced-by-count":0,"title":["Assessment of weight-based variations in effective dose for common PET\/CT scans in a tertiary hospital"],"prefix":"10.1093","volume":"202","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-3713-1841","authenticated-orcid":false,"given":"Abdallah T","family":"Al Said","sequence":"first","affiliation":[{"name":"School of Physics, Universiti Sains Malaysia , 11800 USM Minden, Penang ,","place":["Malaysia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azhar A","family":"Rahman","sequence":"additional","affiliation":[{"name":"School of Physics, Universiti Sains Malaysia , 11800 USM Minden, Penang ,","place":["Malaysia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6545-7384","authenticated-orcid":false,"given":"Laith K","family":"Albadarneh","sequence":"additional","affiliation":[{"name":"Department of Medical Radiologic Technologies, Faculty of Applied Medical Sciences, Al Al-Bayt University , Mafraq ,","place":["Jordan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ammar A","family":"Oglat","sequence":"additional","affiliation":[{"name":"Department of Medical Imaging, Faculty of Applied Medical Sciences, The Hashemite University , Zarqa 13133 ,","place":["Jordan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatin N","family":"Binti A Halim","sequence":"additional","affiliation":[{"name":"Department of Nuclear Medicine, Penang General Hospital , Penang ,","place":["Malaysia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wesal","family":"Firas","sequence":"additional","affiliation":[{"name":"Department of Medical Physics, Faculty of Sciences, Yarmouk University , Irbid 21163 ,","place":["Jordan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yahia","family":"Alshloul","sequence":"additional","affiliation":[{"name":"Princess Basma Teaching Hospital, Ministry of Health , P.O. 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