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These deficits are thought to emerge from differences in neural structure, functioning and connectivity, particularly within the default, salience and frontoparietal networks. However, the relationship between AB and the organization of these networks remains unclear. To address this gap, the current study applied unweighted, undirected graph analyses to resting-state functional magnetic resonance imaging data in a cohort of 161 adolescents (95 female) enriched for exposure to poverty, a risk factor for AB. As prior work indicates that callous-unemotional (CU) traits may moderate the neurocognitive profile of youth AB, we examined CU traits as a moderator. Using multi-informant latent factors, AB was found to be associated with less efficient frontoparietal network topology, a network associated with executive functioning. However, this effect was limited to youth at low or mean levels of CU traits, indicating that these neural differences were specific to those high on AB but not CU traits. Neither AB, CU traits nor their interaction was significantly related to default or salience network topologies. Results suggest that AB, specifically, may be linked with shifts in the architecture of the frontoparietal network.<\/jats:p>","DOI":"10.1093\/scan\/nsad026","type":"journal-article","created":{"date-parts":[[2023,5,6]],"date-time":"2023-05-06T16:52:24Z","timestamp":1683391944000},"source":"Crossref","is-referenced-by-count":14,"title":["Antisocial behavior is associated with reduced frontoparietal network efficiency in youth"],"prefix":"10.1093","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2971-5718","authenticated-orcid":false,"given":"Scott","family":"Tillem","sequence":"first","affiliation":[{"name":"Department of Psychology, University of Michigan , Ann Arbor, MI 48109, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9158-3181","authenticated-orcid":false,"given":"Hailey L","family":"Dotterer","sequence":"additional","affiliation":[{"name":"Department of Psychology, University of Michigan , Ann Arbor, MI 48109, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leigh G","family":"Goetschius","sequence":"additional","affiliation":[{"name":"Department of Psychology, University of Michigan , Ann Arbor, MI 48109, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nestor","family":"Lopez-Duran","sequence":"additional","affiliation":[{"name":"Department of Psychology, University of Michigan , Ann Arbor, MI 48109, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colter","family":"Mitchell","sequence":"additional","affiliation":[{"name":"Department of Psychology, University of Michigan , Ann Arbor, MI 48109, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher S","family":"Monk","sequence":"additional","affiliation":[{"name":"Department of Psychology, University of Michigan , Ann Arbor, MI 48109, 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