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In the current study, participants (N\u2009=\u200920) were scanned using functional magnetic resonance imaging (fMRI), while they performed a covert facial expression naming task. Immediately prior to scanning thetaburst transcranial magnetic stimulation (TMS) was delivered over the right lateral prefrontal cortex (PFC), or the vertex control site. A group whole-brain analysis revealed that TMS induced opposite effects in the neural responses across different brain networks. Stimulation of the right PFC (compared to stimulation of the vertex) decreased neural activity in the left lateral PFC but increased neural activity in three nodes of the default mode network (DMN): the right superior frontal gyrus, right angular gyrus and the bilateral middle cingulate gyrus. A region of interest analysis showed that TMS delivered over the right PFC reduced neural activity across all functionally localised face areas (including in the PFC) compared to TMS delivered over the vertex. These results suggest that visually recognizing facial expressions is dependent on the dynamic interaction of the face-processing network and the DMN. Our study also demonstrates the utility of combined TMS\/fMRI studies for revealing the dynamic interactions between different functional brain networks.<\/jats:p>","DOI":"10.1093\/scan\/nsad072","type":"journal-article","created":{"date-parts":[[2023,11,15]],"date-time":"2023-11-15T09:59:20Z","timestamp":1700042360000},"source":"Crossref","is-referenced-by-count":4,"title":["TMS disruption of\u00a0the lateral prefrontal cortex increases neural activity in\u00a0the default mode network when naming facial expressions"],"prefix":"10.1093","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8526-2111","authenticated-orcid":false,"given":"David","family":"Pitcher","sequence":"first","affiliation":[{"name":"Department of Psychology, University of York , Heslington, York YO105DD, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Magdalena W","family":"Sliwinska","sequence":"additional","affiliation":[{"name":"School of Psychology, Liverpool John Moores University , Liverpool L3 3AF, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9007-3160","authenticated-orcid":false,"given":"Daniel","family":"Kaiser","sequence":"additional","affiliation":[{"name":"Mathematical Institute, Department of Mathematics and Computer Science, Physics, Geography, Justus-Liebig-Universit\u00e4t Gie\u00dfen , Gie\u00dfen 35392, Germany"},{"name":"Center for Mind, Brain and Behaviour, Philipps-Universit\u00e4t Marburg, and Justus-Liebig-Universit\u00e4t Gie\u00dfen , Marburg 35032, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,11,23]]},"reference":[{"issue":"6507","key":"2023120418102635100_R1","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1038\/372669a0","article-title":"Impaired recognition of\u00a0emotion in\u00a0facial expressions following bilateral damage to the human 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