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A particularly important skill is the ability to navigate and interpret interpersonal relationships, which is reflected in part by the maturation of distributed resting networks. However, the relationships between negative social perceptions in youth and long-term alterations in between-network connectivity are limited. To partially address this gap, we utilized longitudinal resting-state functional magnetic resonance imaging (N\u2009=\u200993) with social pain measures from the NIH Toolbox Emotion Battery to determine the links between negative social perceptions on the trajectory of connectivity between the salience, frontoparietal, and default mode networks in the triple network model of psychopathology. Higher scores of perceived hostility, but not perceived rejection, tended to increase functional connectivity between the salience and both frontoparietal and default mode networks over time. These results suggest that more direct forms of threat (hostility) may be more impactful than rejection (limited desired social interactions), highlighting the importance of a dimensional approach to understanding developmental trajectories. While these connectivity changes align with several aberrant connectivity signatures observed across mental health disorders, these phenotypes are not pathognomonic of psychopathology and may reflect adaptive mechanisms in the context of social adversity.<\/jats:p>","DOI":"10.1093\/scan\/nsaf037","type":"journal-article","created":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T03:31:40Z","timestamp":1747279900000},"source":"Crossref","is-referenced-by-count":2,"title":["Social pain is associated with altered developmental trajectories of connectivity among the triple network model of psychopathology"],"prefix":"10.1093","volume":"20","author":[{"given":"Jake J","family":"Son","sequence":"first","affiliation":[{"name":"Institute for Human Neuroscience, Boys Town National Research Hospital , Boys Town, NE 68010,","place":["United States"]},{"name":"Center for Pediatric Brain Health, Boys Town National Research Hospital , Boys Town, NE 68010,","place":["United 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