{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:55:04Z","timestamp":1787068504667,"version":"build-2736575974"},"reference-count":53,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2023,6,28]],"date-time":"2023-06-28T00:00:00Z","timestamp":1687910400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Independent Research Fund"},{"name":"Integrative Psychiatric Research","award":["iPSYCH R102-A9118"],"award-info":[{"award-number":["iPSYCH R102-A9118"]}]},{"name":"Mental Health Services of the Capital Region of Denmark","award":["6152-00002B"],"award-info":[{"award-number":["6152-00002B"]}]},{"DOI":"10.13039\/501100003554","name":"Lundbeck Foundation","doi-asserted-by":"publisher","award":["R322-2019-2311"],"award-info":[{"award-number":["R322-2019-2311"]}],"id":[{"id":"10.13039\/501100003554","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Hypothesis<\/jats:title>\n                    <jats:p>Individuals with schizophrenia or bipolar disorder have attenuated auditory mismatch negativity (MMN) responses, indicating impaired sensory information processing. Computational models of effective connectivity between brain areas underlying MMN responses show reduced connectivity between fronto-temporal areas in individuals with schizophrenia. Here we ask whether children at familial high risk (FHR) of developing a serious mental disorder show similar alterations.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>We recruited 67 children at FHR for schizophrenia, 47 children at FHR for bipolar disorder as well as 59 matched population-based controls from the Danish High Risk and Resilience study. The 11\u201312-year-old participants engaged in a classical auditory MMN paradigm with deviations in frequency, duration, or frequency and duration, while we recorded their EEG. We used dynamic causal modeling (DCM) to infer on the effective connectivity between brain areas underlying MMN.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Results<\/jats:title>\n                    <jats:p>DCM yielded strong evidence for differences in effective connectivity among groups in connections from right inferior frontal gyrus (IFG) to right superior temporal gyrus (STG), along with differences in intrinsic connectivity within primary auditory cortex (A1). Critically, the 2 high-risk groups differed in intrinsic connectivity in left STG and IFG as well as effective connectivity from right A1 to right STG. Results persisted even when controlling for past or present psychiatric diagnoses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>We provide novel evidence that connectivity underlying MMN responses in children at FHR for schizophrenia and bipolar disorder is altered at the age of 11\u201312, echoing findings that have been found in individuals with manifest schizophrenia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/schbul\/sbad092","type":"journal-article","created":{"date-parts":[[2023,6,15]],"date-time":"2023-06-15T02:33:44Z","timestamp":1686796424000},"page":"166-176","source":"Crossref","is-referenced-by-count":4,"title":["Children at Familial High risk of Schizophrenia and Bipolar Disorder Exhibit Altered Connectivity Patterns During Pre-attentive Processing of an Auditory Prediction Error"],"prefix":"10.1093","volume":"50","author":[{"given":"Kit Melissa","family":"Larsen","sequence":"first","affiliation":[{"name":"Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital - Amager and Hvidovre , Copenhagen , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathrine Skak","family":"Madsen","sequence":"additional","affiliation":[{"name":"Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital - Amager and Hvidovre , Copenhagen , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3586-3653","authenticated-orcid":false,"given":"Anna Hester","family":"Ver Loren van Themaat","sequence":"additional","affiliation":[{"name":"Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital - Amager and Hvidovre , Copenhagen , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne Amalie Elgaard","family":"Thorup","sequence":"additional","affiliation":[{"name":"Child and Adolescent Mental Health Centre, Mental Health Services, Capital Region of Denmark , Hellerup , Denmark"},{"name":"Copenhagen Research Centre for Mental Health - CORE, Mental Health Centre Copenhagen, Mental Health Services, Capital Region of Denmark , Copenhagen , Denmark"},{"name":"The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH) , Aarhus , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerstin Jessica","family":"Plessen","sequence":"additional","affiliation":[{"name":"Child and Adolescent Mental Health Centre, Mental Health Services, Capital Region of Denmark , Hellerup , Denmark"},{"name":"Department of Psychiatry, Service of Child and Adolescent Psychiatry, University Medical Center, University of Lausanne , Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ole","family":"Mors","sequence":"additional","affiliation":[{"name":"The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH) , Aarhus , Denmark"},{"name":"Psychosis Research Unit, Aarhus University Hospital Psychiatry, Aarhus , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merete","family":"Nordentoft","sequence":"additional","affiliation":[{"name":"Copenhagen Research Centre for Mental Health - CORE, Mental Health Centre Copenhagen, Mental Health Services, Capital Region of Denmark , Copenhagen , Denmark"},{"name":"The Lundbeck Foundation Initiative for Integrative Psychiatric Research (iPSYCH) , Aarhus , Denmark"},{"name":"Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen , Copenhagen , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hartwig Roman","family":"Siebner","sequence":"additional","affiliation":[{"name":"Danish Research Centre for Magnetic Resonance, Centre for Functional and Diagnostic Imaging and Research, Copenhagen University Hospital - Amager and Hvidovre , Copenhagen , Denmark"},{"name":"Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen , Copenhagen , Denmark"},{"name":"Department of Neurology, Copenhagen University Hospital Bispebjerg , Copenhagen , Denmark"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,6,28]]},"reference":[{"issue":"8","key":"2023122814551924900_CIT0001","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1001\/archgenpsychiatry.2010.86","article-title":"Full spectrum of psychiatric outcomes among offspring with parental history of mental disorder","volume":"67","author":"Dean","year":"2010","journal-title":"Arch Gen Psychiatry."},{"issue":"1","key":"2023122814551924900_CIT0002","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1093\/schbul\/sbt114","article-title":"Risk of mental illness in offspring of parents with schizophrenia, bipolar disorder, and major depressive disorder: A meta-analysis of family high-risk studies","volume":"40","author":"Rasic","year":"2014","journal-title":"Schizophr Bull."},{"issue":"3","key":"2023122814551924900_CIT0003","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1001\/archgenpsychiatry.2010.1","article-title":"Severe mental disorders in offspring with 2 psychiatrically Ill parents","volume":"67","author":"Gottesman","year":"2010","journal-title":"Arch Gen Psychiatry."},{"issue":"1","key":"2023122814551924900_CIT0004","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.schres.2004.12.002","article-title":"Mismatch negativity in schizophrenia: A meta-analysis","volume":"76","author":"Umbricht","year":"2005","journal-title":"Schizophr Res."},{"issue":"1","key":"2023122814551924900_CIT0005","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1515\/revneuro-2021-0010","article-title":"Auditory mismatch negativity in bipolar disorder: A focused review","volume":"33","author":"Raggi","year":"2021","journal-title":"Rev Neurosci."},{"key":"2023122814551924900_CIT0006","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.schres.2017.04.026","article-title":"Mismatch negativity in bipolar disorder: A neurophysiological biomarker of intermediate effect","volume":"191","author":"Hermens","year":"2018","journal-title":"Schizophr Res."},{"issue":"1456","key":"2023122814551924900_CIT0007","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1098\/rstb.2005.1622","article-title":"A theory of cortical responses","volume":"360","author":"Friston","year":"2005","journal-title":"Philos Trans R Soc Lond B Biol Sci."},{"issue":"12","key":"2023122814551924900_CIT0008","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1016\/j.biopsych.2015.08.025","article-title":"A meta-analysis of mismatch negativity in schizophrenia: From clinical risk to disease specificity and progression","volume":"79","author":"Erickson","year":"2016","journal-title":"Biol Psychiatry."},{"key":"2023122814551924900_CIT0009","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1177\/1550059416645980","article-title":"Mismatch negativity in first-episode schizophrenia: a meta-analysis","volume":"48","author":"Haigh","year":"2016","journal-title":"Clin EEG Neurosci."},{"key":"2023122814551924900_CIT0010","doi-asserted-by":"crossref","DOI":"10.1016\/S0304-3940(01)02072-9","volume-title":"Amplitude Reduction of the Mismatch Negativity in First-Degree Relatives of Patients with Schizophrenia","author":"Jessen","year":"2001"},{"issue":"7","key":"2023122814551924900_CIT0011","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1016\/S0006-3223(02)01379-3","article-title":"Duration mismatch negativity in biological relatives of patients with schizophrenia spectrum disorders","volume":"52","author":"Michie","year":"2002","journal-title":"Biol Psychiatry."},{"issue":"2","key":"2023122814551924900_CIT0012","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.biopsych.2011.08.023","article-title":"Duration mismatch negativity and P3a in first-episode psychosis and individuals at ultra-high risk of psychosis","volume":"71","author":"Atkinson","year":"2012","journal-title":"Biol Psychiatry."},{"issue":"6","key":"2023122814551924900_CIT0013","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.biopsych.2013.07.038","article-title":"Automatic auditory processing deficits in schizophrenia and clinical high-risk patients: Forecasting psychosis risk with mismatch negativity","volume":"75","author":"Perez","year":"2014","journal-title":"Biol Psychiatry."},{"key":"2023122814551924900_CIT0014","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.schres.2017.11.005","article-title":"Impaired mismatch negativity to frequency deviants in individuals at ultra-high risk for psychosis, and preliminary evidence for further impairment with transition to psychosis","volume":"191","author":"Lavoie","year":"2018","journal-title":"Schizophr Res."},{"issue":"10","key":"2023122814551924900_CIT0015","doi-asserted-by":"crossref","first-page":"959","DOI":"10.1016\/j.biopsych.2010.09.057","article-title":"Prediction of psychosis by mismatch negativity","volume":"69","author":"Bodatsch","year":"2011","journal-title":"Biol Psychiatry."},{"issue":"11","key":"2023122814551924900_CIT0016","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1016\/j.biopsych.2014.09.025","article-title":"Forecasting psychosis by event-related potentials-systematic review and specific meta-analysis","volume":"77","author":"Bodatsch","year":"2015","journal-title":"Biol Psychiatry."},{"issue":"8","key":"2023122814551924900_CIT0017","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1001\/jamapsychiatry.2022.1417","article-title":"Mismatch negativity in response to auditory deviance and risk for future psychosis in youth at clinical high risk for psychosis","volume":"79","author":"Hamilton","year":"2022","journal-title":"JAMA Psychiatry."},{"issue":"11","key":"2023122814551924900_CIT0018","doi-asserted-by":"crossref","first-page":"1348","DOI":"10.1016\/j.euroneuro.2013.07.007","article-title":"A systematic review and meta-analysis of proton magnetic resonance spectroscopy and mismatch negativity in bipolar disorder","volume":"23","author":"Chitty","year":"2013","journal-title":"Eur Neuropsychopharmacol."},{"key":"2023122814551924900_CIT0019","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.schres.2017.04.019","article-title":"Sensory prediction errors in the continuum of psychosis","volume":"191","author":"Randeniya","year":"2017","journal-title":"Schizophr Res."},{"issue":"2","key":"2023122814551924900_CIT0020","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1176\/appi.ajp.2009.09040574","article-title":"Static and dynamic cognitive deficits in childhood preceding adult schizophrenia: A 30-year study","volume":"167","author":"Reichenberg","year":"2010","journal-title":"Am J Psychiatry."},{"issue":"1","key":"2023122814551924900_CIT0021","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.biopsych.2007.02.016","article-title":"Deviant matters: duration, frequency, and intensity deviants reveal different patterns of mismatch negativity reduction in early and late schizophrenia","volume":"63","author":"Todd","year":"2008","journal-title":"Biol Psychiatry."},{"key":"2023122814551924900_CIT0022","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.ijpsycho.2019.01.006","article-title":"Mismatch negativity and cognitive performance in the course of schizophrenia","volume":"145","author":"Hirt","year":"2019","journal-title":"Int J Psychophysiol."},{"issue":"6","key":"2023122814551924900_CIT0023","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1111\/eip.12792","article-title":"Staging model in psychiatry: Review of the evolution of electroencephalography abnormalities in major psychiatric disorders","volume":"13","author":"Lavoie","year":"2019","journal-title":"Early Interv Psychiatry."},{"key":"2023122814551924900_CIT0024","doi-asserted-by":"crossref","first-page":"115","DOI":"10.3389\/fpsyt.2013.00115","article-title":"Mismatch negativity as a \u201ctranslatable\u201d brain marker toward early intervention for psychosis: A review","volume":"4","author":"Nagai","year":"2013","journal-title":"Front Psychiatry."},{"key":"2023122814551924900_CIT0025","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.biopsycho.2015.10.010","article-title":"Mismatch negativity (MMN) as biomarker predicting psychosis in clinically at-risk individuals","volume":"116","author":"N\u00e4\u00e4t\u00e4nen","year":"2016","journal-title":"Biol Psychol."},{"issue":"1-3","key":"2023122814551924900_CIT0026","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.schres.2011.12.024","article-title":"Abnormal intrinsic and extrinsic connectivity within the magnetic mismatch negativity brain network in schizophrenia: A preliminary study","volume":"135","author":"Dima","year":"2012","journal-title":"Schizophr Res."},{"issue":"4","key":"2023122814551924900_CIT0027","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1093\/schbul\/sbaa188","article-title":"Stronger top-down and weaker bottom-up frontotemporal connections during sensory learning are associated with severity of psychotic phenomena","volume":"47","author":"Dzafic","year":"2021","journal-title":"Schizophr Bull."},{"issue":"1","key":"2023122814551924900_CIT0028","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1002\/hbm.23035","article-title":"Impaired prefrontal synaptic gain in people with psychosis and their relatives during the mismatch negativity","volume":"37","author":"Ranlund","year":"2016","journal-title":"Hum Brain Mapp."},{"key":"2023122814551924900_CIT0029","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.schres.2018.01.026","article-title":"Altered auditory processing and effective connectivity in 22q11.2 deletion syndrome","volume":"197","author":"Larsen","year":"2018","journal-title":"Schizophr Res."},{"key":"2023122814551924900_CIT0030","doi-asserted-by":"crossref","first-page":"101721","DOI":"10.1016\/j.nicl.2019.101721","article-title":"Individuals with 22q11.2 deletion syndrome show intact prediction but reduced adaptation in responses to repeated sounds: Evidence from Bayesian mapping","volume":"22","author":"Larsen","year":"2019","journal-title":"NeuroImage Clin."},{"key":"2023122814551924900_CIT0031","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.schres.2020.05.061","article-title":"Aberrant connectivity in auditory precision encoding in schizophrenia spectrum disorder and across the continuum of psychotic-like experiences","volume":"222","author":"Larsen","year":"2020","journal-title":"Schizophr Res."},{"issue":"2","key":"2023122814551924900_CIT0032","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.biopsych.2021.07.024","article-title":"Computational modeling of electroencephalography and functional magnetic resonance imaging paradigms indicates a consistent loss of pyramidal cell synaptic gain in schizophrenia","volume":"91","author":"Adams","year":"2022","journal-title":"Biol Psychiatry."},{"key":"2023122814551924900_CIT0033","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.schres.2022.06.035","article-title":"Mismatch negativity and P3a amplitude in children with familial high risk of schizophrenia or bipolar disorder \u2013 A Danish register-based EEG study","volume":"246","author":"Ver Loren van Themaat","year":"2022","journal-title":"Schizophr Res."},{"issue":"1","key":"2023122814551924900_CIT0034","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1186\/s12888-015-0616-5","article-title":"The danish high risk and resilience study \u2013 VIA 7 - a cohort study of 520 7-year-old children born of parents diagnosed with either schizophrenia, bipolar disorder or neither of these two mental disorders","volume":"15","author":"Thorup","year":"2015","journal-title":"BMC Psychiatry."},{"key":"2023122814551924900_CIT0035","doi-asserted-by":"crossref","first-page":"661","DOI":"10.3389\/fpsyt.2018.00661","article-title":"The danish high risk and resilience study\u2014VIA 11: study protocol for the first follow-up of the VIA 7 cohort \u2212522 children born to parents with schizophrenia spectrum disorders or bipolar disorder and controls being re-examined for the first time at age 1","volume":"9","author":"Thorup","year":"2018","journal-title":"Front Psychiatry."},{"key":"2023122814551924900_CIT0036","volume-title":"Manual for the Child Behavior Checklist and Revised Child Behavior Profile","author":"Achenbach","year":"1983"},{"issue":"11","key":"2023122814551924900_CIT0037","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1001\/archpsyc.1983.01790100074010","article-title":"A children\u2019s global assessment scale (CGAS)","volume":"40","author":"Shaffer","year":"1983","journal-title":"Arch Gen Psychiatry."},{"issue":"7","key":"2023122814551924900_CIT0038","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1097\/00004583-199707000-00021","article-title":"Schedule for affective disorders and schizophrenia for school-age children-present and lifetime version (K-SADS-PL): Initial reliability and validity data","volume":"36","author":"Kaufman","year":"1997","journal-title":"J Am Acad Child Adolesc Psychiatry."},{"key":"2023122814551924900_CIT0039","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1111\/jcpp.13548","article-title":"Mental disorders in preadolescent children at familial high-risk of schizophrenia or bipolar disorder - a four-year follow-up study: The danish high risk and resilience study, VIA 11","volume":"63","author":"Gregersen","year":"2021","journal-title":"J Child Psychol Psychiatry."},{"issue":"21","key":"2023122814551924900_CIT0040","doi-asserted-by":"crossref","first-page":"8174","DOI":"10.1073\/pnas.0402680101","article-title":"Dynamic mapping of human cortical development during childhood through early adulthood","volume":"101","author":"Gogtay","year":"2004","journal-title":"Proc Natl Acad Sci U S A."},{"key":"2023122814551924900_CIT0041","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.schres.2017.09.047","article-title":"Developmental trajectory of mismatch negativity and visual event-related potentials in healthy controls: Implications for neurodevelopmental vs. neurodegenerative models of schizophrenia","volume":"191","author":"Corcoran","year":"2018","journal-title":"Schizophr Res."},{"issue":"1","key":"2023122814551924900_CIT0042","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1038\/s41386-018-0111-z","article-title":"Sex differences in the developing brain: Insights from multimodal neuroimaging","volume":"44","author":"Kaczkurkin","year":"2018","journal-title":"Neuropsychopharmacol"},{"issue":"5","key":"2023122814551924900_CIT0043","doi-asserted-by":"crossref","first-page":"2620","DOI":"10.1152\/jn.90291.2008","article-title":"Dynamic causal modeling of the response to frequency deviants","volume":"101","author":"Garrido","year":"2009","journal-title":"J Neurophysiol."},{"key":"2023122814551924900_CIT0044","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.neuroimage.2019.06.032","article-title":"A guide to group effective connectivity analysis, part 2: Second level analysis with PEB","volume":"200","author":"Zeidman","year":"2019","journal-title":"Neuroimage."},{"issue":"12","key":"2023122814551924900_CIT0045","first-page":"1085","article-title":"Trajectories of mismatch negativity and p3a amplitude development from ages 9 to 16 years in children with risk factors for schizophrenia","volume":"5","author":"Laurens","year":"2020","journal-title":"Biol Psychiatry Cogn Neurosci Neuroimaging."},{"issue":"6","key":"2023122814551924900_CIT0046","doi-asserted-by":"crossref","first-page":"1718","DOI":"10.1093\/schbul\/sbab031","article-title":"Fronto-temporal disconnection within the presence hallucination network in psychotic patients with passivity experiences","volume":"47","author":"Stripeikyte","year":"2021","journal-title":"Schizophr Bull."},{"key":"2023122814551924900_CIT0047","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/j.neubiorev.2019.07.001","article-title":"Functional neuroimaging in treatment resistant schizophrenia: A systematic review","volume":"104","author":"Molent","year":"2019","journal-title":"Neurosci Biobehav Rev."},{"key":"2023122814551924900_CIT0048","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.jad.2016.11.015","article-title":"Anatomical dysconnectivity in bipolar disorder compared with schizophrenia: A selective review of structural network analyses using diffusion MRI","volume":"209","author":"O\u2019Donoghue","year":"2017","journal-title":"J Affect Disord."},{"key":"2023122814551924900_CIT0049","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.jpsychires.2021.09.034","article-title":"Decreased mismatch negativity and elevated frontal-lateral connectivity in first-episode psychosis","volume":"144","author":"Y\u00fcksel","year":"2021","journal-title":"J Psychiatr Res."},{"key":"2023122814551924900_CIT0050","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/j.schres.2018.01.026","article-title":"Altered auditory processing and effective connectivity in 22q11.2 deletion syndrome","volume":"197","author":"Larsen","year":"2018","journal-title":"Schizophr Res."},{"issue":"2","key":"2023122814551924900_CIT0051","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/s11571-008-9038-0","article-title":"Dynamic causal modelling for EEG and MEG","volume":"2","author":"Kiebel","year":"2008","journal-title":"Cogn Neurodyn."},{"key":"2023122814551924900_CIT0052","first-page":"1","article-title":"Examining selection bias in a population-based cohort study of 522 children with familial high risk of schizophrenia or bipolar disorder, and controls: The danish high risk and resilience study VIA 7","volume":"1","author":"Falkenberg Krantz","year":"2022","journal-title":"Soc Psychiatry Psychiatr Epidemiol."},{"issue":"4","key":"2023122814551924900_CIT0053","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1093\/schbul\/sbv050","article-title":"New targets for prevention of schizophrenia: Is it time for interventions in the premorbid phase","volume":"41","author":"Seidman","year":"2015","journal-title":"Schizophr Bull."}],"container-title":["Schizophrenia Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/schizophreniabulletin\/article-pdf\/50\/1\/166\/54915489\/sbad092.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/schizophreniabulletin\/article-pdf\/50\/1\/166\/54915489\/sbad092.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,28]],"date-time":"2023-12-28T09:56:33Z","timestamp":1703757393000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/schizophreniabulletin\/article\/50\/1\/166\/7209754"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,28]]},"references-count":53,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2023,6,28]]},"published-print":{"date-parts":[[2024,1,1]]}},"URL":"https:\/\/doi.org\/10.1093\/schbul\/sbad092","relation":{},"ISSN":["0586-7614","1745-1701"],"issn-type":[{"value":"0586-7614","type":"print"},{"value":"1745-1701","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,1,1]]},"published":{"date-parts":[[2023,6,28]]}}}