{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T19:48:07Z","timestamp":1785440887295,"version":"3.56.0"},"reference-count":149,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2024,8,29]],"date-time":"2024-08-29T00:00:00Z","timestamp":1724889600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"name":"Brain Science and Brain-Inspired Intelligence Technology","award":["2022ZD0211500"],"award-info":[{"award-number":["2022ZD0211500"]}]},{"name":"Brain Science and Brain-Inspired Intelligence Technology","award":["2021ZD0200500"],"award-info":[{"award-number":["2021ZD0200500"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82021004"],"award-info":[{"award-number":["82021004"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Beijing United Imaging Research Institute of Intelligent Imaging Foundation","award":["CRIBJZD202102"],"award-info":[{"award-number":["CRIBJZD202102"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,3,14]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Background<\/jats:title>\n                  <jats:p>Schizophrenia is conceptualized as a brain connectome disorder that can emerge as early as late childhood and adolescence. However, the underlying neurodevelopmental basis remains unclear. Recent interest has grown in children and adolescent patients who experience symptom onset during critical brain development periods. Inspired by advanced methodological theories and large patient cohorts, Chinese researchers have made significant original contributions to understanding altered brain connectome development in early-onset schizophrenia (EOS).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Study Design<\/jats:title>\n                  <jats:p>We conducted a search of PubMed and Web of Science for studies on brain connectomes in schizophrenia and neurodevelopment. In this selective review, we first address the latest theories of brain structural and functional development. Subsequently, we synthesize Chinese findings regarding mechanisms of brain structural and functional abnormalities in EOS. Finally, we highlight several pivotal challenges and issues in this field.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Study Results<\/jats:title>\n                  <jats:p>Typical neurodevelopment follows a trajectory characterized by gray matter volume pruning, enhanced structural and functional connectivity, improved structural connectome efficiency, and differentiated modules in the functional connectome during late childhood and adolescence. Conversely, EOS deviates with excessive gray matter volume decline, cortical thinning, reduced information processing efficiency in the structural brain network, and dysregulated maturation of the functional brain network. Additionally, common functional connectome disruptions of default mode regions were found in early- and adult-onset patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>Chinese research on brain connectomes of EOS provides crucial evidence for understanding pathological mechanisms. Further studies, utilizing standardized analyses based on large-sample multicenter datasets, have the potential to offer objective markers for early intervention and disease treatment.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/schbul\/sbae148","type":"journal-article","created":{"date-parts":[[2024,8,30]],"date-time":"2024-08-30T02:28:13Z","timestamp":1724984893000},"page":"309-324","source":"Crossref","is-referenced-by-count":21,"title":["Schizophrenia and Neurodevelopment: Insights From Connectome Perspective"],"prefix":"10.1093","volume":"51","author":[{"given":"Xiaoyi","family":"Sun","sequence":"first","affiliation":[{"name":"State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University , Beijing ,","place":["China"]},{"name":"Beijing Key Laboratory of Brain Imaging and Connectomics, Beijing Normal University , Beijing ,","place":["China"]},{"name":"IDG\/McGovern Institute for Brain Research, Beijing Normal University , Beijing ,","place":["China"]},{"name":"School of Systems Science, Beijing Normal University , Beijing ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4615-9132","authenticated-orcid":false,"given":"Mingrui","family":"Xia","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University , Beijing ,","place":["China"]},{"name":"Beijing Key Laboratory of Brain Imaging and Connectomics, Beijing Normal University , Beijing ,","place":["China"]},{"name":"IDG\/McGovern Institute for Brain Research, Beijing Normal University , Beijing ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,8,29]]},"reference":[{"issue":"10323","key":"2025031503075540500_CIT0001","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/S0140-6736(21)01730-X","article-title":"Schizophrenia","volume":"399","author":"Jauhar","year":"2022","journal-title":"Lancet"},{"issue":"3","key":"2025031503075540500_CIT0002","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S2215-0366(18)30511-X","article-title":"Prevalence of mental disorders in China: a cross-sectional epidemiological study","volume":"6","author":"Huang","year":"2019","journal-title":"Lancet Psychiatry"},{"issue":"11","key":"2025031503075540500_CIT0003","doi-asserted-by":"crossref","first-page":"1229","DOI":"10.1038\/nm.4225","article-title":"Developmental timing and critical windows for the treatment of psychiatric disorders","volume":"22","author":"Marin","year":"2016","journal-title":"Nat Med."},{"issue":"1","key":"2025031503075540500_CIT0004","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/s41380-020-0775-8","article-title":"Cortical cellular diversity and development in schizophrenia","volume":"26","author":"Price","year":"2021","journal-title":"Mol Psychiatry"},{"issue":"1","key":"2025031503075540500_CIT0005","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1186\/1471-244X-12-150","article-title":"A systematic review of the long-term outcome of early onset schizophrenia","volume":"12","author":"Clemmensen","year":"2012","journal-title":"BMC Psychiatry"},{"issue":"5","key":"2025031503075540500_CIT0006","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1016\/j.neuron.2014.08.034","article-title":"Great expectations: using whole-brain computational connectomics for understanding neuropsychiatric disorders","volume":"84","author":"Deco","year":"2014","journal-title":"Neuron"},{"issue":"3","key":"2025031503075540500_CIT0007","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1038\/nrn3901","article-title":"The connectomics of brain disorders","volume":"16","author":"Fornito","year":"2015","journal-title":"Nat Rev Neurosci."},{"issue":"4","key":"2025031503075540500_CIT0008","doi-asserted-by":"crossref","first-page":"2296","DOI":"10.1016\/j.neuroimage.2011.12.090","article-title":"Schizophrenia, neuroimaging and connectomics","volume":"62","author":"Fornito","year":"2012","journal-title":"Neuroimage"},{"issue":"4","key":"2025031503075540500_CIT0009","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1097\/WCO.0b013e32833aa567","article-title":"Graph theoretical modeling of brain connectivity","volume":"23","author":"He","year":"2010","journal-title":"Curr Opin Neurol."},{"issue":"1","key":"2025031503075540500_CIT0010","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1093\/schbul\/sbx034","article-title":"Dysfunction of large-scale brain networks in schizophrenia: a meta-analysis of resting-state functional connectivity","volume":"44","author":"Dong","year":"2018","journal-title":"Schizophr Bull."},{"issue":"7906","key":"2025031503075540500_CIT0011","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1038\/s41586-022-04554-y","article-title":"Brain charts for the human lifespan","volume":"604","author":"Bethlehem","year":"2022","journal-title":"Nature"},{"issue":"1","key":"2025031503075540500_CIT0012","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1002\/jnr.24669","article-title":"Functional brain connectivity changes across the human life span: From fetal development to old age","volume":"99","author":"Edde","year":"2021","journal-title":"J Neurosci Res"},{"issue":"44","key":"2025031503075540500_CIT0013","doi-asserted-by":"crossref","first-page":"19067","DOI":"10.1073\/pnas.1009073107","article-title":"White matter maturation reshapes structural connectivity in the late developing human brain","volume":"107","author":"Hagmann","year":"2010","journal-title":"Proc Natl Acad Sci USA"},{"issue":"10","key":"2025031503075540500_CIT0014","doi-asserted-by":"crossref","first-page":"3777","DOI":"10.1002\/hbm.22877","article-title":"Age-related changes in the topological organization of the white matter structural connectome across the human lifespan","volume":"36","author":"Zhao","year":"2015","journal-title":"Hum Brain Mapp."},{"issue":"2","key":"2025031503075540500_CIT0015","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/0006-8993(79)90349-4","article-title":"Synaptic density in human frontal cortex - developmental changes and effects of aging","volume":"163","author":"Huttenlocher","year":"1979","journal-title":"Brain Res."},{"issue":"41","key":"2025031503075540500_CIT0016","doi-asserted-by":"crossref","first-page":"16480","DOI":"10.1073\/pnas.1117943109","article-title":"Prolonged myelination in human neocortical evolution","volume":"109","author":"Miller","year":"2012","journal-title":"Proc Natl Acad Sci USA"},{"issue":"44","key":"2025031503075540500_CIT0017","doi-asserted-by":"crossref","first-page":"13681","DOI":"10.1073\/pnas.1502829112","article-title":"Emergence of system roles in normative neurodevelopment","volume":"112","author":"Gu","year":"2015","journal-title":"Proc Natl Acad Sci USA"},{"key":"2025031503075540500_CIT0018","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.dcn.2013.11.004","article-title":"Topological organization of the human brain functional connectome across the lifespan","volume":"7","author":"Cao","year":"2014","journal-title":"Dev Cogn Neurosci"},{"issue":"10","key":"2025031503075540500_CIT0019","doi-asserted-by":"crossref","first-page":"1049","DOI":"10.1016\/j.scib.2022.01.002","article-title":"Development of functional connectome gradients during childhood and adolescence","volume":"67","author":"Xia","year":"2022","journal-title":"Sci Bull (Beijing)"},{"issue":"11","key":"2025031503075540500_CIT0020","doi-asserted-by":"crossref","first-page":"e190","DOI":"10.1038\/tp.2012.116","article-title":"Progressive loss of cortical gray matter in schizophrenia: a meta-analysis and meta-regression of longitudinal MRI studies","volume":"2","author":"Vita","year":"2012","journal-title":"Transl Psychiatry"},{"issue":"9","key":"2025031503075540500_CIT0021","doi-asserted-by":"crossref","first-page":"644","DOI":"10.1016\/j.biopsych.2018.04.023","article-title":"Cortical brain abnormalities in 4474 individuals with schizophrenia and 5098 control subjects via the Enhancing Neuro Imaging Genetics Through Meta Analysis (ENIGMA) consortium","volume":"84","author":"van Erp","year":"2018","journal-title":"Biol Psychiatry"},{"issue":"6","key":"2025031503075540500_CIT0022","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1038\/mp.2015.69","article-title":"Subcortical brain alterations in major depressive disorder: findings from the ENIGMA Major Depressive Disorder working group","volume":"21","author":"Schmaal","year":"2016","journal-title":"Mol Psychiatry"},{"issue":"9","key":"2025031503075540500_CIT0023","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.biopsych.2008.03.031","article-title":"Meta-analysis of gray matter anomalies in schizophrenia: application of anatomic likelihood estimation and network analysis","volume":"64","author":"Glahn","year":"2008","journal-title":"Biol Psychiatry"},{"issue":"1","key":"2025031503075540500_CIT0024","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1503\/jpn.180245","article-title":"Abnormalities of intrinsic regional brain activity in first-episode and chronic schizophrenia: a meta-analysis of resting-state functional MRI","volume":"45","author":"Gong","year":"2020","journal-title":"J Psychiatry Neurosci"},{"issue":"2","key":"2025031503075540500_CIT0025","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1093\/schbul\/sby045","article-title":"Linked 4-way multimodal brain differences in schizophrenia in a large Chinese Han population","volume":"45","author":"Liu","year":"2019","journal-title":"Schizophr Bull"},{"issue":"1","key":"2025031503075540500_CIT0026","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.biopsych.2018.07.020","article-title":"Dysregulated brain dynamics in a triple-network saliency model of schizophrenia and its relation to psychosis","volume":"85","author":"Supekar","year":"2019","journal-title":"Biol Psychiatry"},{"issue":"6","key":"2025031503075540500_CIT0027","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1093\/schbul\/sbz014","article-title":"Connectome-based patterns of first-episode medication-naive patients with schizophrenia","volume":"45","author":"Cui","year":"2019","journal-title":"Schizophr Bull."},{"key":"2025031503075540500_CIT0028","doi-asserted-by":"crossref","first-page":"105144","DOI":"10.1016\/j.neubiorev.2023.105144","article-title":"The whole-brain connectome landscape in patients with schizophrenia: a systematic review and meta-analysis of graph theoretical characteristics","volume":"148","author":"Gao","year":"2023","journal-title":"Neurosci Biobehav Rev."},{"key":"2025031503075540500_CIT0029","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2017\/3014163","article-title":"Complex brain network analysis and its applications to brain disorders: a survey","volume":"2017","author":"Liu","year":"2017","journal-title":"Complexity"},{"key":"2025031503075540500_CIT0030","first-page":"2801","article-title":"Connectomics in psychiatric research: advances and applications","volume":"11","author":"Cao","year":"2015","journal-title":"Neuropsychiatr Dis Treat."},{"key":"2025031503075540500_CIT0031","doi-asserted-by":"crossref","first-page":"111344","DOI":"10.1016\/j.pscychresns.2021.111344","article-title":"Altered topographical organization of grey matter structural network in early-onset schizophrenia","volume":"316","author":"Zhou","year":"2021","journal-title":"Psychiatry Res Neuroimaging"},{"issue":"2","key":"2025031503075540500_CIT0032","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1093\/schbul\/sbx048","article-title":"Altered white matter connectivity within and between networks in antipsychotic-naive first-episode schizophrenia","volume":"44","author":"Li","year":"2018","journal-title":"Schizophr Bull."},{"key":"2025031503075540500_CIT0033","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1017\/neu.2024.2","article-title":"White matter tract alterations in schizophrenia identified by DTI-based probabilistic tractography: a multisite harmonisation study","volume":"13","author":"Jo","year":"2024","journal-title":"Acta Neuropsychiatr."},{"issue":"1","key":"2025031503075540500_CIT0034","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.nic.2019.09.007","article-title":"Neuroimaging in schizophrenia","volume":"30","author":"Keshavan","year":"2020","journal-title":"Neuroimaging Clin N Am."},{"issue":"3","key":"2025031503075540500_CIT0035","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1007\/s10548-023-00954-z","article-title":"Abnormal structural network communication reflects cognitive deficits in schizophrenia","volume":"36","author":"Zorlu","year":"2023","journal-title":"Brain Topogr."},{"key":"2025031503075540500_CIT0036","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/j.schres.2023.12.033","article-title":"Aberrant interhemispheric structural and functional connectivity within whole brain in schizophrenia","volume":"264","author":"Wang","year":"2024","journal-title":"Schizophr Res."},{"issue":"2-3","key":"2025031503075540500_CIT0037","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.schres.2012.08.021","article-title":"Abnormal topological organization of structural brain networks in schizophrenia","volume":"141","author":"Zhang","year":"2012","journal-title":"Schizophr Res."},{"key":"2025031503075540500_CIT0038","doi-asserted-by":"crossref","first-page":"777447","DOI":"10.3389\/fpsyt.2021.777447","article-title":"The deficits of individual morphological covariance network architecture in schizophrenia patients with and without violence","volume":"12","author":"Shen","year":"2021","journal-title":"Front Psychiatry"},{"issue":"4","key":"2025031503075540500_CIT0039","doi-asserted-by":"crossref","first-page":"2228","DOI":"10.1109\/TCDS.2023.3245600","article-title":"Network analysis on cortical morphometry in first-episode schizophrenia","volume":"15","author":"Yin","year":"2023","journal-title":"IEEE Trans Cogn Dev Syst."},{"issue":"29","key":"2025031503075540500_CIT0040","doi-asserted-by":"crossref","first-page":"9123","DOI":"10.1073\/pnas.1502052112","article-title":"Randomization and resilience of brain functional networks as systems-level endophenotypes of schizophrenia","volume":"112","author":"Lo","year":"2015","journal-title":"Proc Natl Acad Sci USA"},{"issue":"Pt 4","key":"2025031503075540500_CIT0041","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1093\/brain\/awn018","article-title":"Disrupted small-world networks in schizophrenia","volume":"131","author":"Liu","year":"2008","journal-title":"Brain"},{"issue":"6","key":"2025031503075540500_CIT0042","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1093\/schbul\/sby184","article-title":"Preservation effect: cigarette smoking acts on the dynamic of influences among unifying neuropsychiatric triple networks in schizophrenia","volume":"45","author":"Liao","year":"2019","journal-title":"Schizophr Bull."},{"issue":"15","key":"2025031503075540500_CIT0043","doi-asserted-by":"crossref","first-page":"9291","DOI":"10.1093\/cercor\/bhad201","article-title":"Spatiotemporal topological correspondence between blood oxygenation and glucose metabolism revealed by simultaneous fPET-fMRI in brain\u2019s white matter","volume":"33","author":"Li","year":"2023","journal-title":"Cereb Cortex"},{"issue":"15","key":"2025031503075540500_CIT0044","doi-asserted-by":"crossref","first-page":"4331","DOI":"10.1002\/hbm.24705","article-title":"Exploring the functional connectome in white matter","volume":"40","author":"Li","year":"2019","journal-title":"Hum Brain Mapp."},{"issue":"9","key":"2025031503075540500_CIT0045","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/j.scib.2017.03.021","article-title":"Low-frequency blood oxygen level-dependent fluctuations in the brain white matter: more than just noise","volume":"62","author":"Ji","year":"2017","journal-title":"Sci Bull (Beijing)"},{"key":"2025031503075540500_CIT0046","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1016\/j.neuroimage.2018.04.018","article-title":"White-matter functional networks changes in patients with schizophrenia","volume":"190","author":"Jiang","year":"2019","journal-title":"Neuroimage"},{"issue":"1","key":"2025031503075540500_CIT0047","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1002\/hbm.24801","article-title":"Impaired interactions among white-matter functional networks in antipsychotic-naive first-episode schizophrenia","volume":"41","author":"Fan","year":"2020","journal-title":"Hum Brain Mapp."},{"issue":"10","key":"2025031503075540500_CIT0048","doi-asserted-by":"crossref","first-page":"1617","DOI":"10.1038\/s41593-019-0471-7","article-title":"Common brain disorders are associated with heritable patterns of apparent aging of the brain","volume":"22","author":"Kaufmann","year":"2019","journal-title":"Nat Neurosci."},{"issue":"12","key":"2025031503075540500_CIT0049","doi-asserted-by":"crossref","first-page":"681","DOI":"10.1016\/j.tins.2017.10.001","article-title":"Predicting age using neuroimaging: innovative brain ageing biomarkers","volume":"40","author":"Cole","year":"2017","journal-title":"Trends Neurosci."},{"issue":"2","key":"2025031503075540500_CIT0050","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/s41380-018-0098-1","article-title":"Brain age and other bodily \u2018ages\u2019: implications for neuropsychiatry","volume":"24","author":"Cole","year":"2019","journal-title":"Mol Psychiatry"},{"issue":"5","key":"2025031503075540500_CIT0051","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1093\/schbul\/sbt142","article-title":"Accelerated brain aging in schizophrenia and beyond: a neuroanatomical marker of psychiatric disorders","volume":"40","author":"Koutsouleris","year":"2014","journal-title":"Schizophr Bull."},{"issue":"6","key":"2025031503075540500_CIT0052","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1176\/appi.ajp.2015.15070922","article-title":"Accelerated brain aging in schizophrenia: a longitudinal pattern recognition study","volume":"173","author":"Schnack","year":"2016","journal-title":"Am J Psychiatry"},{"key":"2025031503075540500_CIT0053","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/j.pscychresns.2017.05.006","article-title":"BrainAGE score indicates accelerated brain aging in schizophrenia, but not bipolar disorder","volume":"266","author":"Nenadic","year":"2017","journal-title":"Psychiatry Res Neuroimaging"},{"issue":"1","key":"2025031503075540500_CIT0054","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1093\/schbul\/sbx172","article-title":"Brain age in early stages of bipolar disorders or schizophrenia","volume":"45","author":"Hajek","year":"2019","journal-title":"Schizophr Bull."},{"issue":"5","key":"2025031503075540500_CIT0055","doi-asserted-by":"crossref","first-page":"898","DOI":"10.1038\/s41386-018-0298-z","article-title":"Brain structure, cognition, and brain age in schizophrenia, bipolar disorder, and healthy controls","volume":"44","author":"Shahab","year":"2019","journal-title":"Neuropsychopharmacology"},{"issue":"3","key":"2025031503075540500_CIT0056","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1038\/s41380-022-01897-w","article-title":"Brain ageing in schizophrenia: evidence from 26 international cohorts via the ENIGMA Schizophrenia consortium","volume":"28","author":"Constantinides","year":"2023","journal-title":"Mol Psychiatry"},{"issue":"5","key":"2025031503075540500_CIT0057","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1038\/s41591-023-02296-6","article-title":"Heterogeneous aging across multiple organ systems and prediction of chronic disease and mortality","volume":"29","author":"Tian","year":"2023","journal-title":"Nat Med."},{"key":"2025031503075540500_CIT0058","doi-asserted-by":"crossref","first-page":"823502","DOI":"10.3389\/fnagi.2022.823502","article-title":"Multimodal magnetic resonance imaging reveals aberrant brain age trajectory during youth in schizophrenia patients","volume":"14","author":"Huang","year":"2022","journal-title":"Front Aging Neurosci."},{"issue":"1","key":"2025031503075540500_CIT0059","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1038\/s41398-023-02379-5","article-title":"Investigating brain aging trajectory deviations in different brain regions of individuals with schizophrenia using multimodal magnetic resonance imaging and brain-age prediction: a multicenter study","volume":"13","author":"Zhu","year":"2023","journal-title":"Transl Psychiatry"},{"issue":"10","key":"2025031503075540500_CIT0060","doi-asserted-by":"crossref","first-page":"1706","DOI":"10.1017\/S0033291717000137","article-title":"Hippocampal subregion volume changes associated with antipsychotic treatment in first-episode psychosis","volume":"47","author":"Rhindress","year":"2017","journal-title":"Psychol Med."},{"issue":"1","key":"2025031503075540500_CIT0061","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.biopsych.2007.01.004","article-title":"Progressive brain volume loss in schizophrenia over the course of the illness: evidence of maturational abnormalities in early adulthood","volume":"63","author":"van Haren","year":"2008","journal-title":"Biol Psychiatry"},{"issue":"1","key":"2025031503075540500_CIT0062","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1093\/schbul\/sbm103","article-title":"Cortical brain development in schizophrenia: insights from neuroimaging studies in childhood-onset schizophrenia","volume":"34","author":"Gogtay","year":"2008","journal-title":"Schizophr Bull."},{"issue":"3","key":"2025031503075540500_CIT0063","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1002\/1098-2779(2000)6:3<180::AID-MRDD5>3.0.CO;2-I","article-title":"Brain abnormalities observed in childhood-onset schizophrenia: a review of the structural magnetic resonance imaging literature","volume":"6","author":"Sowell","year":"2000","journal-title":"Ment Retard Dev Disabil Res Rev."},{"issue":"2","key":"2025031503075540500_CIT0064","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s007020200019","article-title":"Structural brain abnormalities specific to childhood-onset schizophrenia identified by neuroimaging techniques","volume":"109","author":"Mehler","year":"2002","journal-title":"J Neural Transm (Vienna)"},{"issue":"4","key":"2025031503075540500_CIT0065","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1093\/cercor\/bhac148","article-title":"Systematically mapping gray matter abnormal patterns in drug-naive first-episode schizophrenia from childhood to adolescence","volume":"33","author":"Fan","year":"2023","journal-title":"Cereb Cortex."},{"key":"2025031503075540500_CIT0066","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1016\/j.schres.2019.01.025","article-title":"Altered topological characteristics of morphological brain network relate to language impairment in high genetic risk subjects and schizophrenia patients","volume":"208","author":"Li","year":"2019","journal-title":"Schizophr Res."},{"key":"2025031503075540500_CIT0067","doi-asserted-by":"crossref","first-page":"102468","DOI":"10.1016\/j.ajp.2020.102468","article-title":"Specific white matter connectomic changes in schizophrenia compared with psychotic bipolar disorder","volume":"55","author":"Qiu","year":"2021","journal-title":"Asian J Psychiatr."},{"issue":"2","key":"2025031503075540500_CIT0068","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1093\/schbul\/sby046","article-title":"Shared and distinct functional architectures of brain networks across psychiatric disorders","volume":"45","author":"Xia","year":"2019","journal-title":"Schizophr Bull."},{"issue":"3","key":"2025031503075540500_CIT0069","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1093\/schbul\/sbz111","article-title":"Transdiagnostic dysfunctions in brain modules across patients with schizophrenia, bipolar disorder, and major depressive disorder: a connectome-based study","volume":"46","author":"Ma","year":"2020","journal-title":"Schizophr Bull."},{"issue":"4","key":"2025031503075540500_CIT0070","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.jaac.2020.07.903","article-title":"Abnormal thalamocortical circuit in adolescents with early-onset schizophrenia","volume":"60","author":"Zhang","year":"2021","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"issue":"7","key":"2025031503075540500_CIT0071","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1007\/s00787-017-0958-2","article-title":"Abnormal functional connectivity strength in patients with adolescent-onset schizophrenia: a resting-state fMRI study","volume":"26","author":"Wang","year":"2017","journal-title":"Eur Child Adolesc Psychiatry"},{"issue":"1","key":"2025031503075540500_CIT0072","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1093\/ijnp\/pyx095","article-title":"Decreased resting-state interhemispheric functional connectivity correlated with neurocognitive deficits in drug-naive first-episode adolescent-onset schizophrenia","volume":"21","author":"Liu","year":"2018","journal-title":"Int J Neuropsychopharmacol."},{"key":"2025031503075540500_CIT0073","doi-asserted-by":"crossref","first-page":"115123","DOI":"10.1016\/j.psychres.2023.115123","article-title":"Neuronal dysfunction in individuals at early stage of schizophrenia, a resting-state fMRI study","volume":"322","author":"Ma","year":"2023","journal-title":"Psychiatry Res."},{"issue":"3","key":"2025031503075540500_CIT0074","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1093\/schbul\/sby063","article-title":"Dysregulated maturation of the functional connectome in antipsychotic-naive, first-episode patients with adolescent-onset schizophrenia","volume":"45","author":"Li","year":"2019","journal-title":"Schizophr Bull."},{"issue":"1-2","key":"2025031503075540500_CIT0075","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.schres.2015.07.031","article-title":"Dysfunctional resting-state connectivities of brain regions with structural deficits in drug-naive first-episode schizophrenia adolescents","volume":"168","author":"Zhang","year":"2015","journal-title":"Schizophr Res."},{"key":"2025031503075540500_CIT0076","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.jpsychires.2021.05.052","article-title":"Abnormality of subcortical volume and resting functional connectivity in adolescents with early-onset and prodromal schizophrenia","volume":"140","author":"Wen","year":"2021","journal-title":"J Psychiatr Res."},{"issue":"1","key":"2025031503075540500_CIT0077","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1007\/s11682-021-00505-9","article-title":"Alterations in functional network centrality in first-episode drug-naive adolescent-onset schizophrenia","volume":"16","author":"Zhou","year":"2022","journal-title":"Brain Imaging Behav."},{"key":"2025031503075540500_CIT0078","doi-asserted-by":"crossref","first-page":"102167","DOI":"10.1016\/j.ajp.2020.102167","article-title":"Altered empathy-related resting-state functional connectivity in adolescents with early-onset schizophrenia and autism spectrum disorders","volume":"53","author":"Shi","year":"2020","journal-title":"Asian J Psychiatr."},{"key":"2025031503075540500_CIT0079","doi-asserted-by":"crossref","first-page":"103198","DOI":"10.1016\/j.nicl.2022.103198","article-title":"Abnormal patterns of regional homogeneity and functional connectivity across the adolescent first-episode, adult first-episode and adult chronic schizophrenia","volume":"36","author":"Yang","year":"2022","journal-title":"Neuroimage Clin."},{"issue":"11","key":"2025031503075540500_CIT0080","doi-asserted-by":"crossref","first-page":"3486","DOI":"10.1002\/hbm.25862","article-title":"Multimodal brain deficits shared in early-onset and adult-onset schizophrenia predict positive symptoms regardless of illness stage","volume":"43","author":"Feng","year":"2022","journal-title":"Hum Brain Mapp."},{"issue":"3","key":"2025031503075540500_CIT0081","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.schres.2015.03.003","article-title":"Neuroimaging findings from childhood onset schizophrenia patients and their non-psychotic siblings","volume":"173","author":"Ordonez","year":"2016","journal-title":"Schizophr Res."},{"issue":"4","key":"2025031503075540500_CIT0082","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.chc.2013.06.003","article-title":"Gray matter alterations in schizophrenia high-risk youth and early-onset schizophrenia: a review of structural MRI findings","volume":"22","author":"Brent","year":"2013","journal-title":"Child Adolesc Psychiatr Clin N Am."},{"issue":"4","key":"2025031503075540500_CIT0083","doi-asserted-by":"crossref","first-page":"e42","DOI":"10.1371\/journal.pcbi.0010042","article-title":"The human connectome: a structural description of the human brain","volume":"1","author":"Sporns","year":"2005","journal-title":"PLoS Comput Biol."},{"issue":"2s","key":"2025031503075540500_CIT0084","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S0165-0173(99)00041-7","article-title":"Emerging principles of altered neural circuitry in schizophrenia","volume":"31","author":"Benes","year":"2000","journal-title":"Brain Res Brain Res Rev."},{"issue":"3","key":"2025031503075540500_CIT0085","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1017\/S0954579499002199","article-title":"Brain maturational processes and delayed onset in schizophrenia","volume":"11","author":"Keshavan","year":"1999","journal-title":"Dev Psychopathol."},{"key":"2025031503075540500_CIT0086","doi-asserted-by":"crossref","first-page":"30","DOI":"10.3389\/fpsyt.2014.00030","article-title":"Computational neuropsychiatry - schizophrenia as a cognitive brain network disorder","volume":"5","author":"Dauvermann","year":"2014","journal-title":"Front Psychiatry"},{"issue":"3","key":"2025031503075540500_CIT0087","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1124\/jpet.116.234476","article-title":"Involvement of Neuroinflammation during brain development in social cognitive deficits in autism spectrum disorder and schizophrenia","volume":"358","author":"Nakagawa","year":"2016","journal-title":"J Pharmacol Exp Ther."},{"issue":"3","key":"2025031503075540500_CIT0088","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1093\/oxfordjournals.schbul.a006885","article-title":"Mesoprefrontal dopamine neurons and schizophrenia: role of developmental abnormalities","volume":"27","author":"Finlay","year":"2001","journal-title":"Schizophr Bull."},{"issue":"6617","key":"2025031503075540500_CIT0089","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1038\/385634a0","article-title":"Decreased prefrontal dopamine D1 receptors in schizophrenia revealed by PET","volume":"385","author":"Okubo","year":"1997","journal-title":"Nature"},{"issue":"2","key":"2025031503075540500_CIT0090","doi-asserted-by":"crossref","first-page":"101","DOI":"10.31887\/DCNS.2018.20.2\/gcollin","article-title":"Connectome development and a novel extension to the neurodevelopmental model of schizophrenia","volume":"20","author":"Collin","year":"2018","journal-title":"Dialogues Clin Neurosci."},{"issue":"12","key":"2025031503075540500_CIT0091","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1007\/s11910-023-01325-8","article-title":"Revisiting functional dysconnectivity: a review of three model frameworks in schizophrenia","volume":"23","author":"Harikumar","year":"2023","journal-title":"Curr Neurol Neurosci Rep."},{"key":"2025031503075540500_CIT0092","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.schres.2024.06.031","article-title":"A connectome-wide association study of altered functional connectivity in schizophrenia based on resting-state fMRI","volume":"270","author":"He","year":"2024","journal-title":"Schizophr Res."},{"issue":"6","key":"2025031503075540500_CIT0093","doi-asserted-by":"crossref","first-page":"E452","DOI":"10.1503\/jpn.230037","article-title":"Abnormal interhemispheric functional cooperation in schizophrenia follows the neurotransmitter profiles","volume":"48","author":"He","year":"2023","journal-title":"J Psychiatry Neurosci."},{"issue":"1","key":"2025031503075540500_CIT0094","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1038\/s41380-019-0406-4","article-title":"Opposite effects of dopamine and serotonin on resting-state networks: review and implications for psychiatric disorders","volume":"25","author":"Conio","year":"2020","journal-title":"Mol Psychiatry"},{"key":"2025031503075540500_CIT0095","doi-asserted-by":"crossref","first-page":"102845","DOI":"10.1016\/j.nicl.2021.102845","article-title":"Salience network glutamate and brain connectivity in medication-naive first episode patients - a multimodal magnetic resonance spectroscopy and resting state functional connectivity MRI study","volume":"32","author":"Maximo","year":"2021","journal-title":"Neuroimage Clin."},{"key":"2025031503075540500_CIT0096","doi-asserted-by":"crossref","first-page":"175","DOI":"10.3389\/fpsyt.2013.00175","article-title":"A comparison of neuroimaging findings in childhood onset schizophrenia and autism spectrum disorder: a review of the literature","volume":"4","author":"Baribeau","year":"2013","journal-title":"Front Psychiatry"},{"issue":"4","key":"2025031503075540500_CIT0097","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/nn.4511","article-title":"Delayed stabilization and individualization in connectome development are related to psychiatric disorders","volume":"20","author":"Kaufmann","year":"2017","journal-title":"Nat Neurosci."},{"key":"2025031503075540500_CIT0098","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.jad.2018.04.069","article-title":"Local functional connectivity alterations in schizophrenia, bipolar disorder, and major depressive disorder","volume":"236","author":"Wei","year":"2018","journal-title":"J Affect Disord."},{"issue":"3","key":"2025031503075540500_CIT0099","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1111\/j.1751-7893.2011.00260.x","article-title":"Cross-ethnic differences in severity of symptomatology of individuals with first-episode schizophrenia spectrum disorder","volume":"5","author":"Lim","year":"2011","journal-title":"Early Interv Psychiatry"},{"issue":"5","key":"2025031503075540500_CIT0100","doi-asserted-by":"crossref","first-page":"441","DOI":"10.3109\/09540261.2012.708649","article-title":"Cultural aspects of schizophrenia","volume":"24","author":"Kalra","year":"2012","journal-title":"Int Rev Psychiatry"},{"issue":"2","key":"2025031503075540500_CIT0101","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1177\/002076402128783181","article-title":"Effect of culture and environment on the phenomenology of delusions and hallucinations","volume":"48","author":"Suhail","year":"2002","journal-title":"Int J Soc Psychiatry"},{"issue":"3","key":"2025031503075540500_CIT0102","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1017\/S0033291799008430","article-title":"Factor analysis of symptoms in schizophrenia: differences between White and Caribbean patients in Camberwell","volume":"29","author":"Hutchinson","year":"1999","journal-title":"Psychol Med."},{"issue":"11","key":"2025031503075540500_CIT0103","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1017\/S0033291706008774","article-title":"Incidence of schizophrenia and other psychoses in ethnic minority groups: results from the MRC AESOP Study","volume":"36","author":"Fearon","year":"2006","journal-title":"Psychol Med."},{"issue":"6","key":"2025031503075540500_CIT0104","doi-asserted-by":"crossref","first-page":"1266","DOI":"10.1093\/schbul\/sbv109","article-title":"A neuroanatomical signature for schizophrenia across different ethnic groups","volume":"41","author":"Gong","year":"2015","journal-title":"Schizophr Bull."},{"issue":"9","key":"2025031503075540500_CIT0105","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1001\/jamapsychiatry.2015.0226","article-title":"Delayed development of brain connectivity in adolescents with schizophrenia and their unaffected siblings","volume":"72","author":"Zalesky","year":"2015","journal-title":"JAMA Psychiatry"},{"key":"2025031503075540500_CIT0106","doi-asserted-by":"crossref","first-page":"147","DOI":"10.3389\/fnsys.2010.00147","article-title":"Disrupted modularity and local connectivity of brain functional networks in childhood-onset schizophrenia","volume":"4","author":"Alexander-Bloch","year":"2010","journal-title":"Front Syst Neurosci."},{"issue":"1","key":"2025031503075540500_CIT0107","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1093\/cercor\/bhr388","article-title":"The anatomical distance of functional connections predicts brain network topology in health and schizophrenia","volume":"23","author":"Alexander-Bloch","year":"2013","journal-title":"Cereb Cortex"},{"key":"2025031503075540500_CIT0108","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.schres.2018.01.003","article-title":"Attenuated resting-state functional connectivity in patients with childhood- and adult-onset schizophrenia","volume":"197","author":"Watsky","year":"2018","journal-title":"Schizophr Res."},{"issue":"Pt 1","key":"2025031503075540500_CIT0109","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1093\/brain\/awv306","article-title":"Disrupted sensorimotor and social-cognitive networks underlie symptoms in childhood-onset schizophrenia","volume":"139","author":"Berman","year":"2016","journal-title":"Brain"},{"issue":"10039","key":"2025031503075540500_CIT0110","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/S0140-6736(15)01121-6","article-title":"Schizophrenia","volume":"388","author":"Owen","year":"2016","journal-title":"Lancet"},{"issue":"2","key":"2025031503075540500_CIT0111","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1017\/S0033291719000084","article-title":"Individual differences v. the average patient: mapping the heterogeneity in ADHD using normative models","volume":"50","author":"Wolfers","year":"2020","journal-title":"Psychol Med."},{"issue":"7","key":"2025031503075540500_CIT0112","doi-asserted-by":"crossref","first-page":"3512","DOI":"10.1038\/s41380-020-00882-5","article-title":"Individual deviations from normative models of brain structure in a large cross-sectional schizophrenia cohort","volume":"26","author":"Lv","year":"2021","journal-title":"Mol Psychiatry"},{"key":"2025031503075540500_CIT0113","doi-asserted-by":"crossref","first-page":"e72904","DOI":"10.7554\/eLife.72904","article-title":"Charting brain growth and aging at high spatial precision","volume":"11","author":"Rutherford","year":"2022","journal-title":"eLife"},{"issue":"3","key":"2025031503075540500_CIT0114","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1016\/j.neuron.2012.12.028","article-title":"Individual variability in functional connectivity architecture of the human brain","volume":"77","author":"Mueller","year":"2013","journal-title":"Neuron"},{"issue":"3","key":"2025031503075540500_CIT0115","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1093\/schbul\/sbaa155","article-title":"Disrupted intersubject variability architecture in functional connectomes in schizophrenia","volume":"47","author":"Sun","year":"2021","journal-title":"Schizophr Bull."},{"issue":"7","key":"2025031503075540500_CIT0116","doi-asserted-by":"crossref","first-page":"678","DOI":"10.1001\/jamapsychiatry.2015.0505","article-title":"Two patterns of white matter abnormalities in medication-naive patients with first-episode schizophrenia revealed by diffusion tensor imaging and cluster analysis","volume":"72","author":"Sun","year":"2015","journal-title":"JAMA Psychiatry"},{"issue":"3","key":"2025031503075540500_CIT0117","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1038\/s44220-023-00024-0","article-title":"Neuroimaging biomarkers define neurophysiological subtypes with distinct trajectories in schizophrenia","volume":"1","author":"Jiang","year":"2023","journal-title":"Nat Mental Health"},{"issue":"1","key":"2025031503075540500_CIT0118","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1093\/schbul\/sbab110","article-title":"Subtyping schizophrenia patients based on patterns of structural brain alterations","volume":"48","author":"Xiao","year":"2022","journal-title":"Schizophr Bull."},{"issue":"7","key":"2025031503075540500_CIT0119","doi-asserted-by":"crossref","first-page":"2991","DOI":"10.1038\/s41380-020-00892-3","article-title":"Identifying and validating subtypes within major psychiatric disorders based on frontal-posterior functional imbalance via deep learning","volume":"26","author":"Chang","year":"2021","journal-title":"Mol Psychiatry"},{"key":"2025031503075540500_CIT0120","doi-asserted-by":"crossref","first-page":"105554","DOI":"10.1016\/j.compbiomed.2022.105554","article-title":"An overview of artificial intelligence techniques for diagnosis of Schizophrenia based on magnetic resonance imaging modalities: methods, challenges, and future works","volume":"146","author":"Sadeghi","year":"2022","journal-title":"Comput Biol Med."},{"issue":"12","key":"2025031503075540500_CIT0121","doi-asserted-by":"crossref","first-page":"3468","DOI":"10.1002\/hbm.25013","article-title":"Towards a brain-based predictome of mental illness","volume":"41","author":"Rashid","year":"2020","journal-title":"Hum Brain Mapp."},{"issue":"11","key":"2025031503075540500_CIT0122","doi-asserted-by":"crossref","first-page":"1852","DOI":"10.1017\/S0033291719001934","article-title":"Detecting schizophrenia at the level of the individual: relative diagnostic value of whole-brain images, connectome-wide functional connectivity and graph-based metrics","volume":"50","author":"Lei","year":"2020","journal-title":"Psychol Med."},{"key":"2025031503075540500_CIT0123","doi-asserted-by":"crossref","first-page":"102284","DOI":"10.1016\/j.nicl.2020.102284","article-title":"Identifying commonality and specificity across psychosis sub-groups via classification based on features from dynamic connectivity analysis","volume":"27","author":"Du","year":"2020","journal-title":"Neuroimage Clin."},{"key":"2025031503075540500_CIT0124","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.ebiom.2019.08.023","article-title":"Discriminating schizophrenia using recurrent neural network applied on time courses of multi-site FMRI data","volume":"47","author":"Yan","year":"2019","journal-title":"eBioMedicine"},{"issue":"6","key":"2025031503075540500_CIT0125","doi-asserted-by":"crossref","first-page":"2536","DOI":"10.1109\/JBHI.2021.3139701","article-title":"Inferring the individual psychopathologic deficits with structural connectivity in a longitudinal cohort of schizophrenia","volume":"26","author":"Sun","year":"2022","journal-title":"IEEE J Biomed Health Inform."},{"key":"2025031503075540500_CIT0126","doi-asserted-by":"crossref","first-page":"kkae005","DOI":"10.1093\/psyrad\/kkae005","article-title":"Transcriptomic and neuroimaging data integration enhances machine learning classification of schizophrenia","volume":"4","author":"Wang","year":"2024","journal-title":"Psychoradiology"},{"key":"2025031503075540500_CIT0127","doi-asserted-by":"crossref","first-page":"1140801","DOI":"10.3389\/fnins.2023.1140801","article-title":"Discriminative analysis of schizophrenia patients using graph convolutional networks: a combined multimodal MRI and connectomics analysis","volume":"17","author":"Chen","year":"2023","journal-title":"Front Neurosci."},{"issue":"2","key":"2025031503075540500_CIT0128","first-page":"422","article-title":"Functional, anatomical, and morphological networks highlight the role of basal ganglia-thalamus-cortex circuits in schizophrenia","volume":"46","author":"Zhao","year":"2020","journal-title":"Schizophr Bull."},{"issue":"6","key":"2025031503075540500_CIT0129","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1192\/bjp.2022.22","article-title":"Consistent brain structural abnormalities and multisite individualised classification of schizophrenia using deep neural networks","volume":"221","author":"Cui","year":"2022","journal-title":"Br J Psychiatry."},{"key":"2025031503075540500_CIT0130","doi-asserted-by":"crossref","first-page":"102860","DOI":"10.1016\/j.nicl.2021.102860","article-title":"Multisite schizophrenia classification by integrating structural magnetic resonance imaging data with polygenic risk score","volume":"32","author":"Hu","year":"2021","journal-title":"Neuroimage Clin."},{"key":"2025031503075540500_CIT0131","first-page":"56","article-title":"A deep learning fusion model for brain disorder classification: application to distinguishing schizophrenia and autism spectrum disorder","volume":"2020","author":"Du","year":"2020","journal-title":"ACM BCB."},{"issue":"12","key":"2025031503075540500_CIT0132","doi-asserted-by":"crossref","first-page":"3887","DOI":"10.1002\/hbm.25890","article-title":"A new multimodality fusion classification approach to explore the uniqueness of schizophrenia and autism spectrum disorder","volume":"43","author":"Du","year":"2022","journal-title":"Hum Brain Mapp."},{"issue":"2","key":"2025031503075540500_CIT0133","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1093\/schbul\/sbab112","article-title":"Cerebello-thalamo-cortical hyperconnectivity classifies patients and predicts long-term treatment outcome in first-episode schizophrenia","volume":"48","author":"Cao","year":"2022","journal-title":"Schizophr Bull."},{"issue":"4","key":"2025031503075540500_CIT0134","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1093\/schbul\/sbac047","article-title":"Graph convolutional networks reveal network-level functional dysconnectivity in schizophrenia","volume":"48","author":"Lei","year":"2022","journal-title":"Schizophr Bull."},{"key":"2025031503075540500_CIT0135","doi-asserted-by":"crossref","first-page":"119297","DOI":"10.1016\/j.neuroimage.2022.119297","article-title":"A deep learning-based multisite neuroimage harmonization framework established with a traveling-subject dataset","volume":"257","author":"Tian","year":"2022","journal-title":"Neuroimage"},{"key":"2025031503075540500_CIT0136","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.neuroimage.2017.02.031","article-title":"Functional connectomics from a \u201cbig data\u201d perspective","volume":"160","author":"Xia","year":"2017","journal-title":"Neuroimage"},{"issue":"5","key":"2025031503075540500_CIT0137","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1002\/hbm.25307","article-title":"Individual-specific functional connectome biomarkers predict schizophrenia positive symptoms during adolescent brain maturation","volume":"42","author":"Fan","year":"2020","journal-title":"Hum Brain Mapp."},{"issue":"3","key":"2025031503075540500_CIT0138","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1176\/ajp.155.3.355","article-title":"Schizophrenia as a long-term outcome of pregnancy, delivery, and perinatal complications: a 28-year follow-up of the 1966 north Finland general population birth cohort","volume":"155","author":"Jones","year":"1998","journal-title":"Am J Psychiatry."},{"issue":"7321","key":"2025031503075540500_CIT0139","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1038\/nature09563","article-title":"The environment and schizophrenia","volume":"468","author":"van Os","year":"2010","journal-title":"Nature"},{"issue":"6","key":"2025031503075540500_CIT0140","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1037\/abn0000765","article-title":"Age-dependent effects of schizophrenia genetic risk on cortical thickness and cortical surface area: evaluating evidence for neurodevelopmental and neurodegenerative models of schizophrenia","volume":"131","author":"Kuo","year":"2022","journal-title":"J Psychopathol Clin Sci."},{"issue":"1","key":"2025031503075540500_CIT0141","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1038\/mp.2014.158","article-title":"Common polygenic variation and risk for childhood-onset schizophrenia","volume":"21","author":"Ahn","year":"2016","journal-title":"Mol Psychiatry."},{"issue":"5","key":"2025031503075540500_CIT0142","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1038\/mp.2013.59","article-title":"High rate of disease-related copy number variations in childhood onset schizophrenia","volume":"19","author":"Ahn","year":"2014","journal-title":"Mol Psychiatry."},{"issue":"1","key":"2025031503075540500_CIT0143","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1093\/schbul\/sbad087","article-title":"Linking polygenic risk of schizophrenia to variation in magnetic resonance imaging brain measures: a comprehensive systematic review","volume":"50","author":"Jameei","year":"2024","journal-title":"Schizophr Bull."},{"issue":"1","key":"2025031503075540500_CIT0144","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.schres.2005.05.009","article-title":"Review of longitudinal functional neuroimaging studies of drug treatments in patients with schizophrenia","volume":"78","author":"Davis","year":"2005","journal-title":"Schizophr Res."},{"issue":"8","key":"2025031503075540500_CIT0145","doi-asserted-by":"crossref","first-page":"1680","DOI":"10.1016\/j.neubiorev.2013.06.001","article-title":"Progressive brain changes in schizophrenia related to antipsychotic treatment? A meta-analysis of longitudinal MRI studies","volume":"37","author":"Fusar-Poli","year":"2013","journal-title":"Neurosci Biobehav Rev."},{"key":"2025031503075540500_CIT0146","doi-asserted-by":"crossref","first-page":"104","DOI":"10.3389\/fnsys.2016.00104","article-title":"Cortico-Striatal-Thalamic loop circuits of the salience network: a central pathway in psychiatric disease and treatment","volume":"10","author":"Peters","year":"2016","journal-title":"Front Syst Neurosci."},{"issue":"11","key":"2025031503075540500_CIT0147","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1177\/2045125318782306","article-title":"Are structural brain changes in schizophrenia related to antipsychotic medication? A narrative review of the evidence from a clinical perspective","volume":"8","author":"Lawrie","year":"2018","journal-title":"Ther Adv Psychopharmacol."},{"issue":"2","key":"2025031503075540500_CIT0148","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1038\/s41591-022-02197-0","article-title":"New and emerging approaches to treat psychiatric disorders","volume":"29","author":"Scangos","year":"2023","journal-title":"Nat Med."},{"issue":"10","key":"2025031503075540500_CIT0149","doi-asserted-by":"crossref","first-page":"1652","DOI":"10.1176\/appi.ajp.157.10.1652","article-title":"Adult outcomes of child- and adolescent-onset schizophrenia: diagnostic stability and predictive validity","volume":"157","author":"Hollis","year":"2000","journal-title":"Am J Psychiatry."}],"container-title":["Schizophrenia Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/schizophreniabulletin\/article-pdf\/51\/2\/309\/58967374\/sbae148.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/schizophreniabulletin\/article-pdf\/51\/2\/309\/58967374\/sbae148.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,15]],"date-time":"2025-03-15T03:08:53Z","timestamp":1742008133000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/schizophreniabulletin\/article\/51\/2\/309\/7745479"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,29]]},"references-count":149,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2024,8,29]]},"published-print":{"date-parts":[[2025,3,14]]}},"URL":"https:\/\/doi.org\/10.1093\/schbul\/sbae148","relation":{},"ISSN":["0586-7614","1745-1701"],"issn-type":[{"value":"0586-7614","type":"print"},{"value":"1745-1701","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,3]]},"published":{"date-parts":[[2024,8,29]]}}}