{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T04:35:33Z","timestamp":1787978133962,"version":"build-2784847793"},"reference-count":34,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2024,11,28]],"date-time":"2024-11-28T00:00:00Z","timestamp":1732752000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000269","name":"Economic and Social Research Council","doi-asserted-by":"publisher","award":["ES\/S002715\/1"],"award-info":[{"award-number":["ES\/S002715\/1"]}],"id":[{"id":"10.13039\/501100000269","id-type":"DOI","asserted-by":"publisher"}]},{"name":"ESRC managed by King\u2019s College London"},{"name":"ESRC Centre for Society and Mental Health at King\u2019s College London","award":["ES\/S012567\/1"],"award-info":[{"award-number":["ES\/S012567\/1"]}]},{"DOI":"10.13039\/501100000272","name":"National Institute for Health and Care Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019418","name":"Maudsley Biomedical Research Centre","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019418","id-type":"DOI","asserted-by":"publisher"}]},{"name":"South London and Maudsley NHS Foundation Trust and King\u2019s College London"},{"name":"Population Mental Health Consortium","award":["MR\/Y030788\/1"],"award-info":[{"award-number":["MR\/Y030788\/1"]}]},{"name":"Population Health Improvement UK"},{"DOI":"10.13039\/501100023232","name":"NIHR Applied Research Collaboration South London","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100023232","id-type":"DOI","asserted-by":"publisher"}]},{"name":"King\u2019s College Hospital NHS Foundation"},{"name":"DATAMIND HDR UK Mental Health Data Hub","award":["MR\/W014386"],"award-info":[{"award-number":["MR\/W014386"]}]},{"DOI":"10.13039\/100031401","name":"UK Prevention Research Partnership","doi-asserted-by":"publisher","award":["MR-VO49879\/1"],"award-info":[{"award-number":["MR-VO49879\/1"]}],"id":[{"id":"10.13039\/100031401","id-type":"DOI","asserted-by":"publisher"}]},{"name":"UK Research and Innovation Councils"},{"DOI":"10.13039\/501100000276","name":"Department of Health and Social Care","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000276","id-type":"DOI","asserted-by":"publisher"}]},{"name":"UK devolved administrations, and leading health research charities"},{"name":"National Statistics Secure Research Service"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The association of social and clinical indicators with employment, disability, and health outcomes among individuals with severe mental illnesses (SMI) remains unclear. Existing evidence primarily comes from smaller cohort studies limited by shorter follow-up and high attrition, or registry-based research, which lacks information on important social determinants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>We utilized a novel data linkage consisting of clinical records of individuals diagnosed with schizophrenia-spectrum or bipolar disorders from the South London and Maudsley Mental Health Trust, linked at the individual-level to the 2011 UK Census, a rich source for sociodemographic information. Using logistic regression, we estimated adjusted odds ratios (aORs) and 95% confidence intervals to determine associations between socioeconomic and clinical indicators and economic inactivity, self-rated health, and disability outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The sample comprised 8249 people with SMI diagnoses. Economic inactivity (77.3%), disability (68.3%) and poor health (61.1%) were highly prevalent. Longer duration of illness and comorbid substance misuse were associated with economic inactivity, poorer self-rated health, and disability, with associations noted between living alone and all outcomes (aORs and 95% CI: Economic inactivity: 1.72, 1.45-2.03; disability: 1.48, 1.31-1.68; poor health: 1.32, 1.18-1.49). Relative to the White British group, Black African, South Asian, and Other Black groups were more likely to be economically inactive. Black Caribbean and other groups were less likely to report poorer self-rated health or disability.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our findings highlight considerable disability, poorer health, and economic inactivity experienced by people with SMI. Addressing comorbid substance misuse and social isolation could play a role in improving outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/schbul\/sbae195","type":"journal-article","created":{"date-parts":[[2024,11,2]],"date-time":"2024-11-02T00:22:33Z","timestamp":1730506953000},"page":"1367-1379","source":"Crossref","is-referenced-by-count":7,"title":["Health, Disability, and Economic Inactivity Following a Diagnosis of a Severe Mental Illness: Cohort Study of Electronic Health Records Linked at the Individual-Level, to Census from England"],"prefix":"10.1093","volume":"51","author":[{"given":"L","family":"Cybulski","sequence":"first","affiliation":[{"name":"King\u2019s College London, Institute of Psychiatry Psychology and Neuroscience Department of Psychological Medicine, , London, SE5 8AF ,","place":["United Kingdom"]},{"name":"Division of Insurance Medicine, Karolinska Institutet , 171 77\u00a0Stockholm ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M E","family":"Dewey","sequence":"additional","affiliation":[{"name":"Health Service and Population Research Department, Institute of Psychiatry, Psychology and Neuroscience, King\u2019s College London , London, SE5 8AF ,\u00a0","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Hildersley","sequence":"additional","affiliation":[{"name":"King\u2019s College London, Institute of Psychiatry Psychology and Neuroscience Department of Psychological Medicine, , London, SE5 8AF ,","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Morgan","sequence":"additional","affiliation":[{"name":"Health Service and Population Research Department, Institute of Psychiatry, Psychology and Neuroscience, King\u2019s College London , London, SE5 8AF ,\u00a0","place":["United Kingdom"]},{"name":"Centre for Society & Mental Health, King\u2019s College London , London , ;\u00a0","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R","family":"Stewart","sequence":"additional","affiliation":[{"name":"King\u2019s College London, Institute of Psychiatry Psychology and Neuroscience Department of Psychological Medicine, , London, SE5 8AF ,","place":["United Kingdom"]},{"name":"South London and Maudsley NHS Foundation Trust , London , \u00a0","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Wuerth","sequence":"additional","affiliation":[{"name":"King\u2019s College London, Institute of Psychiatry Psychology and Neuroscience Department of Psychological Medicine, , London, SE5 8AF ,","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3913-6859","authenticated-orcid":false,"given":"J","family":"Das-Munshi","sequence":"additional","affiliation":[{"name":"King\u2019s College London, Institute of Psychiatry Psychology and Neuroscience Department of Psychological Medicine, , London, SE5 8AF ,","place":["United Kingdom"]},{"name":"Centre for Society & Mental Health, King\u2019s College London , London , ;\u00a0","place":["United Kingdom"]},{"name":"Population Heath Improvement UK (PHI-UK) , ;\u00a0","place":["United Kingdom"]},{"name":"South London and Maudsley NHS Foundation Trust , London , \u00a0","place":["United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,11,28]]},"reference":[{"key":"2025090719515461900_CIT0001","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1001\/jamapsychiatry.2013.1394","article-title":"Comorbidities and mortality in bipolar disorder: a Swedish national cohort study","volume":"70","author":"Crump","year":"2013","journal-title":"JAMA Psychiatry."},{"key":"2025090719515461900_CIT0002","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1111\/j.1600-0447.2007.01095.x","article-title":"Physical illness and schizophrenia: a review of the literature","volume":"116","author":"Leucht","year":"2007","journal-title":"Acta Psychiatr Scand."},{"key":"2025090719515461900_CIT0003","doi-asserted-by":"crossref","first-page":"2581","DOI":"10.1017\/S0033291720001087","article-title":"How do ethnicity and deprivation impact on life expectancy at birth in people with serious mental illness? Observational study in the UK","volume":"51","author":"Das-Munshi","year":"2021","journal-title":"Psychol Med."},{"key":"2025090719515461900_CIT0004","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1001\/jamapsychiatry.2015.1737","article-title":"Premature mortality among adults with schizophrenia in the United States","volume":"72","author":"Olfson","year":"2015","journal-title":"JAMA Psychiatry."},{"key":"2025090719515461900_CIT0005","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1001\/archpsyc.64.10.1123","article-title":"A systematic review of mortality in schizophrenia. is the differential mortality gap worsening over time","volume":"64","author":"Saha","year":"2007","journal-title":"Arch Gen Psychiatry."},{"key":"2025090719515461900_CIT0006","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1007\/s00127-004-0762-4","article-title":"Schizophrenia and employment - a review","volume":"39","author":"Marwaha","year":"2004","journal-title":"Soc Psychiatry 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Orthopsychiatry."},{"key":"2025090719515461900_CIT0031","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/S2215-0366(17)30097-4","article-title":"Ethnicity and excess mortality in severe mental illness: a cohort study","volume":"4","author":"Das-Munshi","year":"2017","journal-title":"Lancet Psychiatry."},{"key":"2025090719515461900_CIT0032","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/S2215-0366(19)30126-9","article-title":"Ethnic density and other neighbourhood associations for mortality in severe mental illness: a retrospective cohort study with multi-level analysis from an urbanised and ethnically diverse location in the UK","volume":"6","author":"Das-Munshi","year":"2019","journal-title":"Lancet Psychiatry."},{"key":"2025090719515461900_CIT0033","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/S2215-0366(19)30164-6","article-title":"Neighbourhood and mortality in severe mental 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Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/schizophreniabulletin\/article-pdf\/51\/5\/1367\/60896173\/sbae195.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/schizophreniabulletin\/article-pdf\/51\/5\/1367\/60896173\/sbae195.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,7]],"date-time":"2025-09-07T23:52:04Z","timestamp":1757289124000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/schizophreniabulletin\/article\/51\/5\/1367\/7912352"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,28]]},"references-count":34,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2024,11,28]]},"published-print":{"date-parts":[[2025,9,8]]}},"URL":"https:\/\/doi.org\/10.1093\/schbul\/sbae195","relation":{},"ISSN":["0586-7614","1745-1701"],"issn-type":[{"value":"0586-7614","type":"print"},{"value":"1745-1701","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,9]]},"published":{"date-parts":[[2024,11,28]]}}}