{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T10:58:53Z","timestamp":1791197933134,"version":"4.1.0"},"reference-count":42,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T00:00:00Z","timestamp":1787184000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100017266","name":"Government of Navarra","doi-asserted-by":"publisher","award":["17\/31"],"award-info":[{"award-number":["17\/31"]}],"id":[{"id":"10.13039\/501100017266","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017266","name":"Government of Navarra","doi-asserted-by":"publisher","award":["18\/41"],"award-info":[{"award-number":["18\/41"]}],"id":[{"id":"10.13039\/501100017266","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017266","name":"Government of Navarra","doi-asserted-by":"publisher","award":["GN2025\/56"],"award-info":[{"award-number":["GN2025\/56"]}],"id":[{"id":"10.13039\/501100017266","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Spanish Ministry of Economy and Competitiveness","award":["PI16\/02148"],"award-info":[{"award-number":["PI16\/02148"]}],"id":[{"id":"https:\/\/ror.org\/01txxn211","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Spanish Ministry of Economy and Competitiveness","award":["PI19\/01698"],"award-info":[{"award-number":["PI19\/01698"]}],"id":[{"id":"https:\/\/ror.org\/01txxn211","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Spanish Ministry of Economy and Competitiveness","award":["RD21\/0009\/0025"],"award-info":[{"award-number":["RD21\/0009\/0025"]}],"id":[{"id":"https:\/\/ror.org\/01txxn211","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Spanish Ministry of Economy and Competitiveness","award":["RD24\/0003\/0015"],"award-info":[{"award-number":["RD24\/0003\/0015"]}],"id":[{"id":"https:\/\/ror.org\/01txxn211","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Spanish Ministry of Economy and Competitiveness","award":["PI25\/01433"],"award-info":[{"award-number":["PI25\/01433"]}],"id":[{"id":"https:\/\/ror.org\/01txxn211","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,20]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Hypothesis<\/jats:title>\n                    <jats:p>Motor abnormalities (MAs) are intrinsic features of the psychosis spectrum, but their longitudinal associations with cognition and functioning remain unclear. We hypothesized that Positive and Negative Syndrome Scale (PANSS)-derived hypokinetic and hyperkinetic motor dimensions would be associated with cognitive and functional outcomes and that distinct longitudinal motor trajectories would capture clinically relevant heterogeneity in first-episode psychosis (FEP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>In a multicenter naturalistic FEP cohort, 159 patients completed clinical, functional, and neurocognitive assessments at 2\u00a0months and 2\u00a0years. PANSS-derived motor dimensions were assessed longitudinally. Cross-sectional and longitudinal associations with cognition and functioning were examined using correlational, mixed-effects, and trajectory-based analyses, including growth mixture modeling.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Results<\/jats:title>\n                    <jats:p>At 2\u00a0months, hypokinetic severity was associated with poorer verbal memory (r\u2009=\u2009\u22120.252, p\u2009=\u2009.002), whereas hyperkinetic severity was associated with poorer vocabulary (r\u2009=\u2009\u22120.260, p\u2009=\u2009.001) and verbal memory (r\u2009=\u2009\u22120.237, P\u2009=\u2009.003). Prospectively, higher 2-month hyperkinetic severity was associated with poorer vocabulary (r\u2009=\u2009\u22120.282, P\u2009&amp;lt;\u2009.001), verbal memory (r\u2009=\u2009\u22120.366, P\u2009&amp;lt;\u2009.001), and global cognition (r\u2009=\u2009\u22120.309, P\u2009=\u2009.001) at 2\u00a0years. Mixed-effects analyses confirmed associations between hyperkinetic severity and poorer longitudinal verbal memory trajectory (\u03b2\u2009=\u2009\u22120.295, P\u2009=\u2009.019). Higher-severity hyperkinetic trajectories remained associated with poorer 2-year verbal memory (\u03b2\u2009=\u2009\u22120.858, P\u2009=\u2009.003) and functional outcome (\u03b2\u2009=\u200910.209, P\u2009=\u2009.005).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>PANSS-derived motor dimensions capture meaningful longitudinal heterogeneity in FEP. Sustained hyperkinetic severity was consistently associated with poorer verbal memory and functional outcome over time, supporting the relevance of MAs as longitudinal correlates of cognitive and functional variability in early psychosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/schbul\/sbag128","type":"journal-article","created":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T11:22:01Z","timestamp":1781695321000},"source":"Crossref","is-referenced-by-count":0,"title":["Longitudinal Motor Trajectories and 2-Year Cognitive and Functional Outcomes in First-Episode Psychosis"],"prefix":"10.1093","volume":"52","author":[{"given":"Eloi","family":"Gin\u00e9-Serv\u00e9n","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Hospital Universitario de Navarra , Pamplona 31008 ,","place":["Spain"]},{"name":"Instituto de Investigaci\u00f3n Sanitaria de Navarra (IdiSNA) , Pamplona 31008 ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo J","family":"Gil-Berrozpe","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Hospital Universitario de Navarra , Pamplona 31008 ,","place":["Spain"]},{"name":"Instituto de Investigaci\u00f3n Sanitaria de Navarra (IdiSNA) , Pamplona 31008 ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro","family":"Ballesteros","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Sanitaria de Navarra (IdiSNA) , Pamplona 31008 ,","place":["Spain"]},{"name":"Mental Health Department, Servicio Navarro de Salud , Pamplona 31008 ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Amoretti","sequence":"additional","affiliation":[{"name":"Bipolar and Depressive Disorders Unit, Hospital Cl\u00ednic de Barcelona , Barcelona 08036 ,","place":["Spain"]},{"name":"Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Institute of Research (VHIR), Instituto de Investigaci\u00f3n Sanitaria Hospital Universitari Vall d'Hebron (IIS IR-HUVH) , Barcelona 08035 ,","place":["Spain"]},{"name":"Fundaci\u00f3 de Recerca Cl\u00ednic Barcelona-Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (FRCB-IDIBAPS) , Barcelona 08036 ,","place":["Spain"]},{"name":"Departament de Medicina, Institut de Neuroci\u00e8ncies (UBNeuro), University of Barcelona , Barcelona 08035 ,","place":["Spain"]},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III , Madrid 28029 ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Florencia","family":"Forte","sequence":"additional","affiliation":[{"name":"Bipolar and Depressive Disorders Unit, Hospital Cl\u00ednic de Barcelona , Barcelona 08036 ,","place":["Spain"]},{"name":"Fundaci\u00f3 de Recerca Cl\u00ednic Barcelona-Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (FRCB-IDIBAPS) , Barcelona 08036 ,","place":["Spain"]},{"name":"Departament de Medicina, Institut de Neuroci\u00e8ncies (UBNeuro), University of Barcelona , Barcelona 08035 ,","place":["Spain"]},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III , Madrid 28029 ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joaqu\u00edn","family":"Galva\u00f1","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Mara\u00f1\u00f3n, IiSGM, School of Medicine, Universidad Complutense, Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental (CIBERSAM) , Madrid 28030 ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gisela","family":"Mezquida","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3 de Recerca Cl\u00ednic Barcelona-Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (FRCB-IDIBAPS) , Barcelona 08036 ,","place":["Spain"]},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III , Madrid 28029 ,","place":["Spain"]},{"name":"Departament de Medicina, Facultat de Medicina i Ci\u00e8ncies de la Salut, Institut de Neuroci\u00e8ncies (UBNeuro), Universitat de Barcelona (UB) , Barcelona 08035 ,","place":["Spain"]},{"name":"Barcelona Cl\u00ednic Schizophrenia Unit, Hospital Cl\u00ednic de Barcelona , Barcelona 08036 ,","place":["Spain"]},{"name":"Serra-Hunter Lecturer Fellow, Department of Basic Clinal Practice, Pharmacology Unit, Universitat de Barcelona (UB) , Barcelona 08028 ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0548-0053","authenticated-orcid":false,"given":"Eduard","family":"Vieta","sequence":"additional","affiliation":[{"name":"Bipolar and Depressive Disorders Unit, Hospital Cl\u00ednic de Barcelona , Barcelona 08036 ,","place":["Spain"]},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III , Madrid 28029 ,","place":["Spain"]},{"name":"Departament de Medicina, Facultat de Medicina i Ci\u00e8ncies de la Salut, Institut de Neuroci\u00e8ncies (UBNeuro), Universitat de Barcelona (UB) , Barcelona 08035 ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Renzo","family":"Abreg\u00fa-Crespo","sequence":"additional","affiliation":[{"name":"Department of Child and Adolescent Psychiatry, Institute of Psychiatry and Mental Health, Hospital General Universitario Gregorio Maranon, School of Medicine, Universidad Complutense, IiSGM, CIBERSAM, ISCIII , Madrid 28009 ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana","family":"S\u00e1nchez-Torres","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Sanitaria de Navarra (IdiSNA) , Pamplona 31008 ,","place":["Spain"]},{"name":"Departamento de Ciencias de la Salud, Universidad P\u00fablica de Navarra (UPNA) , Pamplona 31008 ,","place":["Espa\u00f1a"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amira","family":"Trabsa","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III , Madrid 28029 ,","place":["Spain"]},{"name":"Hospital del Mar , Institute of Mental Health, Hospital del Mar, Barcelona 08003 ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"de la Serna","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3 de Recerca Cl\u00ednic Barcelona-Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (FRCB-IDIBAPS) , Barcelona 08036 ,","place":["Spain"]},{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III , Madrid 28029 ,","place":["Spain"]},{"name":"Department of Child and Adolescent Psychiatry and Psychology, SGR2021-01319, Hospital Clinic , Barcelona 08036 ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Labad","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III , Madrid 28029 ,","place":["Spain"]},{"name":"Department of Mental Health and Addictions, Consorci Sanitari del Maresme, Hospital Universitari de Matar\u00f3, UAB , Matar\u00f3 08304 ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miquel","family":"Bernardo","sequence":"additional","affiliation":[{"name":"Fundaci\u00f3 de Recerca Cl\u00ednic Barcelona-Institut d'Investigacions Biom\u00e8diques August Pi i Sunyer (FRCB-IDIBAPS) , Barcelona 08036 ,","place":["Spain"]},{"name":"Barcelona Cl\u00ednic Schizophrenia Unit (BCSU), Neuroscience Institute, Hospital Cl\u00ednic of Barcelona , Barcelona 08036 ,","place":["Spain"]},{"name":"Barcelona Cl\u00ednic Schizophrenia Unit, Hospital Cl\u00ednic of Barcelona , Barcelona 08036 ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel J","family":"Cuesta","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Hospital Universitario de Navarra , Pamplona 31008 ,","place":["Spain"]},{"name":"Instituto de Investigaci\u00f3n Sanitaria de Navarra (IdiSNA) , Pamplona 31008 ,","place":["Spain"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"PEPs group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,8,25]]},"reference":[{"key":"2026100505590011000_ref1","doi-asserted-by":"publisher","first-page":"956","DOI":"10.1093\/schbul\/sbx089","article-title":"Motor abnormalities: from neurodevelopmental to neurodegenerative through \u201cfunctional\u201d (neuro)psychiatric disorders","volume":"43","author":"Peralta","year":"2017","journal-title":"Schizophr Bull"},{"key":"2026100505590011000_ref2","doi-asserted-by":"publisher","first-page":"741","DOI":"10.1093\/schbul\/sbac003","article-title":"Motor behavior is relevant for understanding mechanism, bolstering prediction, and improving treatment: a transdiagnostic perspective","volume":"48","author":"Walther","year":"2022","journal-title":"Schizophr Bull"},{"key":"2026100505590011000_ref3","doi-asserted-by":"publisher","first-page":"807","DOI":"10.1176\/appi.ajp.20250533","article-title":"Future of sensorimotor and psychomotor dysfunction in mental disorders: emerging tools, methodological challenges, and the road ahead","volume":"182","author":"Hirjak","year":"2025","journal-title":"Am J Psychiatry"},{"key":"2026100505590011000_ref4","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1093\/schbul\/sbac026","article-title":"(Developmental) motor signs: reconceptualizing a potential transdiagnostic marker of psychopathological vulnerability","volume":"48","author":"Poletti","year":"2022","journal-title":"Schizophr Bull"},{"key":"2026100505590011000_ref5","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1016\/j.schres.2019.07.032","article-title":"Functional and structural correlates of abnormal involuntary movements in psychosis risk and first episode psychosis","volume":"212","author":"Kindler","year":"2019","journal-title":"Schizophr Res"},{"key":"2026100505590011000_ref6","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.biopsych.2010.01.021","article-title":"Markers of basal ganglia dysfunction and conversion to psychosis: neurocognitive deficits and dyskinesias in the prodromal period","volume":"68","author":"Mittal","year":"2010","journal-title":"Biol Psychiatry"},{"key":"2026100505590011000_ref7","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1093\/schbul\/sbn146","article-title":"Dyskinesia and parkinsonism in antipsychotic-naive patients with schizophrenia, first-degree relatives and healthy controls: a meta-analysis","volume":"36","author":"Koning","year":"2010","journal-title":"Schizophr Bull"},{"key":"2026100505590011000_ref8","doi-asserted-by":"publisher","first-page":"1065","DOI":"10.1017\/S0033291708004716","article-title":"Spontaneous movement disorders in antipsychotic-naive patients with first-episode psychoses: a systematic review","volume":"39","author":"Pappa","year":"2009","journal-title":"Psychol Med"},{"key":"2026100505590011000_ref9","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.schres.2017.10.035","article-title":"Motor abnormalities and cognitive impairment in first-episode psychosis patients, their unaffected siblings and healthy controls","volume":"200","author":"Cuesta","year":"2018","journal-title":"Schizophr Res"},{"key":"2026100505590011000_ref10","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1002\/wps.20807","article-title":"Primary psychosis: more to know, much more to do","volume":"20","author":"Carpenter","year":"2021","journal-title":"World Psychiatry"},{"key":"2026100505590011000_ref11","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1016\/S0920-9964(01)00390-5","article-title":"Neurological soft-signs in psychosis: threshold criteria for discriminating normal controls and for predicting cognitive impairment","volume":"58","author":"Cuesta","year":"2002","journal-title":"Schizophr Res"},{"key":"2026100505590011000_ref12","doi-asserted-by":"publisher","first-page":"438","DOI":"10.1097\/JCP.0b013e31828f62b0","article-title":"Phenomenological differences between spontaneous and drug-related extrapyramidal syndromes in patients with schizophrenia-spectrum disorders","volume":"33","author":"Peralta","year":"2013","journal-title":"J Clin Psychopharmacol"},{"key":"2026100505590011000_ref13","doi-asserted-by":"publisher","first-page":"691","DOI":"10.1016\/j.neubiorev.2021.11.027","article-title":"A systematic review of the prognostic value of motor abnormalities on clinical outcome in psychosis","volume":"132","author":"Pieters","year":"2022","journal-title":"Neurosci Biobehav Rev"},{"key":"2026100505590011000_ref14","doi-asserted-by":"publisher","first-page":"13","DOI":"10.3389\/fpsyt.2022.877566","article-title":"Catatonia and cognitive impairments: a systematic review","volume":"13","author":"Serrat","year":"2022","journal-title":"Front Psychiatry"},{"key":"2026100505590011000_ref15","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1093\/schbul\/13.2.261","article-title":"The positive and negative syndrome scale (PANSS) for schizophrenia","volume":"13","author":"Kay","year":"1987","journal-title":"Schizophr Bull"},{"key":"2026100505590011000_ref16","doi-asserted-by":"publisher","first-page":"1162","DOI":"10.1093\/schbul\/sbae153","article-title":"Testing a motor score based on PANSS ratings: a proxy for comprehensive motor assessment","volume":"51","author":"Nadesalingam","year":"2025","journal-title":"Schizophr Bull"},{"key":"2026100505590011000_ref17","doi-asserted-by":"publisher","first-page":"1164","DOI":"10.1093\/schbul\/sbt125","article-title":"Spontaneous parkinsonism is associated with cognitive impairment in antipsychotic-naive patients with first-episode psychosis: a 6-month follow-up study","volume":"40","author":"Cuesta","year":"2014","journal-title":"Schizophr Bull"},{"key":"2026100505590011000_ref18","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1038\/s41537-022-00270-8","article-title":"Extrapyramidal symptoms predict cognitive performance after first-episode psychosis","volume":"8","author":"Lindgren","year":"2022","journal-title":"Schizophrenia."},{"key":"2026100505590011000_ref19","doi-asserted-by":"publisher","first-page":"1625","DOI":"10.1007\/s00406-024-01782-3","article-title":"Deciphering the interplay between psychopathological symptoms, sensorimotor, cognitive and global functioning: a transdiagnostic network analysis","volume":"274","author":"Fritze","year":"2024","journal-title":"Eur Arch Psychiatry Clin Neurosci"},{"key":"2026100505590011000_ref20","doi-asserted-by":"publisher","first-page":"16","DOI":"10.1038\/s41537-024-00547-0","article-title":"Sensori- and psychomotor abnormalities, psychopathological symptoms and functionality in schizophrenia-spectrum disorders: a network analytic approach","volume":"11","author":"Fritze","year":"2025","journal-title":"Schizophrenia."},{"key":"2026100505590011000_ref21","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1016\/S2215-0366(18)30474-7","article-title":"Structure and neural mechanisms of catatonia","volume":"6","author":"Walther","year":"2019","journal-title":"Lancet Psychiatry"},{"key":"2026100505590011000_ref22","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1016\/j.rpsm.2012.11.001","article-title":"Criterios de valoraci\u00f3n cl\u00ednicos y de funcionamiento en un estudio de interacci\u00f3n gen-ambiente en primeros episodios psic\u00f3ticos (PEPs)","volume":"6","author":"Bernardo","year":"2013","journal-title":"Rev Psiquiatr Salud Ment"},{"key":"2026100505590011000_ref23","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/j.rpsm.2019.03.001","article-title":"Una d\u00e9cada del proyecto de primeros episodios psic\u00f3ticos (PEPs): Avanzando hacia una psiquiatr\u00eda de precisi\u00f3n","volume":"12","author":"Bernardo","year":"2019","journal-title":"Rev Psiquiatr Salud Ment"},{"key":"2026100505590011000_ref24","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.schres.2015.02.022","article-title":"Premorbid adjustment and clinical correlates of cognitive impairment in first-episode psychosis. The PEPsCog study","volume":"164","author":"Cuesta","year":"2015","journal-title":"Schizophr Res"},{"key":"2026100505590011000_ref25","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1016\/j.euroneuro.2025.03.011","article-title":"Comparing PANSS-6 and PANSS-30 for clinical and functional outcomes in first-episode psychosis: a 2-year follow-up in a Spanish cohort","volume":"95","author":"Llorca-Bof\u00ed","year":"2025","journal-title":"Eur Neuropsychopharmacol"},{"key":"2026100505590011000_ref26","doi-asserted-by":"publisher","first-page":"e89428","DOI":"10.1371\/journal.pone.0089428","article-title":"Increased prolactin levels are associated with impaired processing speed in subjects with early psychosis","volume":"9","author":"Montalvo","year":"2014","journal-title":"PLoS One"},{"key":"2026100505590011000_ref27","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1176\/appi.ajp.2007.07010042","article-title":"The MATRICS consensus cognitive battery, part 1: test selection, reliability, and validity","volume":"165","author":"Nuechterlein","year":"2008","journal-title":"Am J Psychiatry"},{"key":"2026100505590011000_ref28","doi-asserted-by":"publisher","first-page":"98","DOI":"10.1016\/j.euroneuro.2021.02.007","article-title":"The functioning assessment short test (FAST) applied to first-episode psychosis: psychometric properties and severity thresholds","volume":"47","author":"Amoretti","year":"2021","journal-title":"Eur Neuropsychopharmacol"},{"key":"2026100505590011000_ref29","doi-asserted-by":"publisher","first-page":"1486","DOI":"10.1093\/schbul\/sbw023","article-title":"Prediction of neurocognitive deficits by parkinsonian motor impairment in schizophrenia: a study in neuroleptic-na\u00efve subjects, unaffected first-degree relatives and healthy controls from an indigenous population","volume":"42","author":"Molina","year":"2016","journal-title":"Schizophr Bull"},{"key":"2026100505590011000_ref30","doi-asserted-by":"publisher","first-page":"S900","DOI":"10.1016\/S0924-977X(17)31604-8","article-title":"Catatonia is associated with worse cognitive performance in antipsychotic-naive patients with first-episode psychosis: a 3-month follow-up study","volume":"27","author":"Colomer","year":"2017","journal-title":"Eur Neuropsychopharmacol"},{"key":"2026100505590011000_ref31","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1016\/j.psychres.2014.12.048","article-title":"Abnormal movements in first-episode, nonaffective psychosis: dyskinesias, stereotypies, and catatonic-like signs","volume":"226","author":"Compton","year":"2015","journal-title":"Psychiatry Res"},{"key":"2026100505590011000_ref32","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.schres.2022.05.005","article-title":"The network structure of cognitive deficits in first episode psychosis patients","volume":"244","author":"S\u00e1nchez-Torres","year":"2022","journal-title":"Schizophr Res"},{"key":"2026100505590011000_ref33","doi-asserted-by":"publisher","first-page":"f","DOI":"10.1016\/j.psychres.2022.114933","article-title":"Neurocognitive correlates of the varied domains of outcomes at 20 year follow-up of first-episode psychosis","volume":"318","author":"Cuesta","year":"2022","journal-title":"Psychiatry Res"},{"key":"2026100505590011000_ref34","doi-asserted-by":"publisher","first-page":"229","DOI":"10.1016\/j.schres.2022.05.026","article-title":"Neuromotor dysfunction as a major outcome domain of psychotic disorders: a 21-year follow-up study","volume":"263","author":"Peralta","year":"2024","journal-title":"Schizophr Res"},{"key":"2026100505590011000_ref35","doi-asserted-by":"publisher","first-page":"152307","DOI":"10.1016\/j.comppsych.2022.152307","article-title":"Motor abnormalities are associated with poor social and functional outcomes in schizophrenia","volume":"115","author":"Nadesalingam","year":"2022","journal-title":"Compr Psychiatry"},{"key":"2026100505590011000_ref36","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1038\/s41380-020-0814-5","article-title":"All roads lead to the motor cortex: psychomotor mechanisms and their biochemical modulation in psychiatric disorders","volume":"26","author":"Northoff","year":"2021","journal-title":"Mol Psychiatry"},{"key":"2026100505590011000_ref37","doi-asserted-by":"publisher","first-page":"125","DOI":"10.1016\/j.eurpsy.2017.04.004","article-title":"Motor system dysfunction in the schizophrenia diathesis: neural systems to neurotransmitters","volume":"44","author":"Abboud","year":"2017","journal-title":"Eur Psychiatry"},{"key":"2026100505590011000_ref38","doi-asserted-by":"publisher","first-page":"1423","DOI":"10.1093\/brain\/awad395","article-title":"The pathobiology of psychomotor slowing in psychosis: altered cortical excitability and connectivity","volume":"147","author":"Lefebvre","year":"2024","journal-title":"Brain."},{"key":"2026100505590011000_ref39","doi-asserted-by":"publisher","DOI":"10.7916\/D8SN07PK","article-title":"The neuropsychiatry of hyperkinetic movement disorders: insights from neuroimaging into the neural circuit bases of dysfunction","volume":"3","author":"Hayhow","year":"2013","journal-title":"Tremor Other Hyperkinet Mov (N Y)"},{"key":"2026100505590011000_ref40","doi-asserted-by":"publisher","first-page":"840","DOI":"10.1176\/appi.ajp.20240780","article-title":"Grip strength as a marker of resting-state network integrity and well-being in early psychosis","volume":"182","author":"Ward","year":"2025","journal-title":"Am J Psychiatry"},{"key":"2026100505590011000_ref41","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1016\/j.biopsych.2024.02.1013","article-title":"Isolation of distinct networks driving action and cognition in psychomotor processes","volume":"96","author":"Moussa-Tooks","year":"2024","journal-title":"Biol Psychiatry"},{"key":"2026100505590011000_ref42","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1016\/j.euroneuro.2020.07.003","article-title":"Movement disorder and sensorimotor abnormalities in schizophrenia and other psychoses - European consensus on assessment and perspectives","volume":"38","author":"Walther","year":"2020","journal-title":"Eur Neuropsychopharmacol"}],"container-title":["Schizophrenia Bulletin"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/schizophreniabulletin\/article-pdf\/52\/5\/sbag128\/70785929\/sbag128.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/schizophreniabulletin\/article-pdf\/52\/5\/sbag128\/70785929\/sbag128.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T09:59:10Z","timestamp":1791194350000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/schizophreniabulletin\/article\/doi\/10.1093\/schbul\/sbag128\/8770520"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,20]]},"references-count":42,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,8,20]]}},"URL":"https:\/\/doi.org\/10.1093\/schbul\/sbag128","relation":{},"ISSN":["0586-7614","1745-1701"],"issn-type":[{"value":"0586-7614","type":"print"},{"value":"1745-1701","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,9]]},"published":{"date-parts":[[2026,8,20]]},"article-number":"sbag128"}}