{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T09:08:52Z","timestamp":1791623332163,"version":"4.3.4"},"reference-count":98,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2017,12,1]],"date-time":"2017-12-01T00:00:00Z","timestamp":1512086400000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1125000"],"award-info":[{"award-number":["APP1125000"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["GNT1059660"],"award-info":[{"award-number":["GNT1059660"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000269","name":"Economic and Social Research Council","doi-asserted-by":"publisher","award":["ESJ5000991"],"award-info":[{"award-number":["ESJ5000991"]}],"id":[{"id":"10.13039\/501100000269","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000272","name":"National Institute for Health Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,10,17]]},"DOI":"10.1093\/schbul\/sbx162","type":"journal-article","created":{"date-parts":[[2017,10,27]],"date-time":"2017-10-27T07:08:23Z","timestamp":1509088103000},"page":"1275-1292","source":"Crossref","is-referenced-by-count":80,"title":["Nutritional Deficiencies and Clinical Correlates in First-Episode Psychosis: A Systematic Review and Meta-analysis"],"prefix":"10.1093","volume":"44","author":[{"given":"Joseph","family":"Firth","sequence":"first","affiliation":[{"name":"NICM, School of Science and Health, University of Western Sydney, Sydney, Australia"},{"name":"Division of Psychology and Mental Health, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebekah","family":"Carney","sequence":"additional","affiliation":[{"name":"Division of Psychology and Mental Health, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brendon","family":"Stubbs","sequence":"additional","affiliation":[{"name":"Physiotherapy Department, South London and Maudsley NHS Foundation Trust, London, UK"},{"name":"Department of Psychological Medicine, Institute of Psychiatry, Psychology and Neuroscience, King\u2019s College London, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott B","family":"Teasdale","sequence":"additional","affiliation":[{"name":"Keeping the Body in Mind Program, South Eastern Sydney Local Health District, Sydney, Australia"},{"name":"School of Psychiatry, University of New South Wales, Sydney, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davy","family":"Vancampfort","sequence":"additional","affiliation":[{"name":"KU Leuven Department of Rehabilitation Sciences, Leuven, Belgium"},{"name":"KU Leuven Department of Neurosciences, UPC KU Leuven, Leuven, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip B","family":"Ward","sequence":"additional","affiliation":[{"name":"School of Psychiatry, University of New South Wales, Sydney, Australia"},{"name":"Schizophrenia Research Unit, Ingham Institute of Applied Medical Research, Liverpool, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Berk","sequence":"additional","affiliation":[{"name":"Deakin University, School of Medicine, IMPACT Strategic Research Centre, Barwon Health, Geelong, Australia"},{"name":"Florey Institute of Neuroscience and Mental Health, University of Melbourne, Melbourne, Australia"},{"name":"Orygen, The National Centre of Excellence in Youth Mental Health and Orygen Youth Health Research Centre, Melbourne, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jerome","family":"Sarris","sequence":"additional","affiliation":[{"name":"NICM, School of Science and Health, University of Western Sydney, Sydney, Australia"},{"name":"Department of Psychiatry, University of Melbourne, The Melbourne Clinic, Melbourne, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2017,11,30]]},"reference":[{"key":"key\n\t\t\t\t20181017114324773_CIT0001","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S2215-0366(14)00051-0","article-title":"Nutritional medicine as mainstream in psychiatry","volume":"2","author":"Sarris","year":"2015","journal-title":"Lancet Psychiatry"},{"key":"key\n\t\t\t\t20181017114324773_CIT0002","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1002\/wps.20223","article-title":"International Society for Nutritional Psychiatry Research consensus position statement: nutritional medicine in modern psychiatry","volume":"14","author":"Sarris","year":"2015","journal-title":"World Psychiatry"},{"key":"key\n\t\t\t\t20181017114324773_CIT0003","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1192\/bjp.bp.108.058925","article-title":"Dietary pattern and depressive symptoms in middle age","volume":"195","author":"Akbaraly","year":"2009","journal-title":"Br J Psychiatry"},{"key":"key\n\t\t\t\t20181017114324773_CIT0004","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1176\/appi.ajp.2009.09060881","article-title":"Association of Western and traditional diets with depression and anxiety in women","volume":"167","author":"Jacka","year":"2010","journal-title":"Am J Psychiatry"},{"key":"key\n\t\t\t\t20181017114324773_CIT0005","doi-asserted-by":"crossref","first-page":"e31","DOI":"10.2105\/AJPH.2014.302110","article-title":"Relationship between diet and mental health in children and adolescents: a systematic review","volume":"104","author":"O\u2019Neil","year":"2014","journal-title":"Am J Public Health"},{"key":"key\n\t\t\t\t20181017114324773_CIT0006","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1016\/j.schres.2015.10.043","article-title":"Diet, exercise and the metabolic syndrome in schizophrenia: A cross-sectional study","volume":"169","author":"Heald","year":"2015","journal-title":"Schizophr Res"},{"key":"key\n\t\t\t\t20181017114324773_CIT0007","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.jpsychires.2012.10.005","article-title":"The dietary pattern of patients with schizophrenia: a systematic review","volume":"47","author":"Dipasquale","year":"2013","journal-title":"J Psychiatr Res"},{"key":"key\n\t\t\t\t20181017114324773_CIT0008","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.schres.2011.06.008","article-title":"Life expectancy among persons with schizophrenia or bipolar affective disorder","volume":"131","author":"Laursen","year":"2011","journal-title":"Schizophr Res"},{"key":"key\n\t\t\t\t20181017114324773_CIT0009","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.jpsychires.2009.10.011","article-title":"Folate, homocysteine, interleukin-6, and tumor necrosis factor alfa levels, but not the methylenetetrahydrofolate reductase C677T polymorphism, are risk factors for schizophrenia","volume":"44","author":"Garc\u00eda-Miss","year":"2010","journal-title":"J Psychiatr Res"},{"key":"key\n\t\t\t\t20181017114324773_CIT0010","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.psychres.2010.04.008","article-title":"Plasma homocysteine in schizophrenia: determinants and clinical correlations in Tunisian patients free from antipsychotics","volume":"179","author":"Bouaziz","year":"2010","journal-title":"Psychiatry Res"},{"key":"key\n\t\t\t\t20181017114324773_CIT0011","doi-asserted-by":"crossref","first-page":"1705","DOI":"10.1176\/appi.ajp.161.9.1705","article-title":"Folate, homocysteine, and negative symptoms in schizophrenia","volume":"161","author":"Goff","year":"2004","journal-title":"Am J Psychiatry"},{"key":"key\n\t\t\t\t20181017114324773_CIT0012","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1017\/S0033291717000022","article-title":"The effects of vitamin and mineral supplementation on symptoms of schizophrenia: a systematic review and meta-analysis","volume":"47","author":"Firth","year":"2017","journal-title":"Psychol Med"},{"key":"key\n\t\t\t\t20181017114324773_CIT0013","article-title":"Biochemical, physiological and clinical effects of l-methylfolate in schizophrenia: a randomized controlled trial","author":"Roffman","year":"2017","journal-title":"Mol Psychiatry"},{"key":"key\n\t\t\t\t20181017114324773_CIT0014","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.2174\/0929867033456864","article-title":"Folate and homocysteine metabolism: therapeutic targets in cardiovascular and neurodegenerative disorders","volume":"10","author":"Mattson","year":"2003","journal-title":"Curr Med Chem"},{"key":"key\n\t\t\t\t20181017114324773_CIT0015","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1038\/sj.mp.4001746","article-title":"Homocysteine, methylenetetrahydrofolate reductase and risk of schizophrenia: a meta-analysis","volume":"11","author":"Muntjewerff","year":"2006","journal-title":"Mol Psychiatry"},{"key":"key\n\t\t\t\t20181017114324773_CIT0016","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.biopsych.2013.03.018","article-title":"Meta-analysis of oxidative stress in schizophrenia","volume":"74","author":"Flatow","year":"2013","journal-title":"Biol Psychiatry"},{"key":"key\n\t\t\t\t20181017114324773_CIT0017","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1111\/j.1600-0447.2010.01551.x","article-title":"Is it time to trial vitamin D supplements for the prevention of schizophrenia","volume":"121","author":"McGrath","year":"2010","journal-title":"Acta Psychiatr Scand"},{"key":"key\n\t\t\t\t20181017114324773_CIT0018","first-page":"A4","article-title":"Environmental risk factors for schizophrenia: does developmental vitamin D deficiency play a role","volume":"44","author":"McGrath","year":"2010","journal-title":"Aust N Z J Psychiatry"},{"key":"key\n\t\t\t\t20181017114324773_CIT0019","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0920-9964(02)00435-8","article-title":"Low maternal vitamin D as a risk factor for schizophrenia: a pilot study using banked sera","volume":"63","author":"McGrath","year":"2003","journal-title":"Schizophr Res"},{"key":"key\n\t\t\t\t20181017114324773_CIT0020","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.schres.2003.08.005","article-title":"Vitamin D supplementation during the first year of life and risk of schizophrenia: a Finnish birth cohort study","volume":"67","author":"McGrath","year":"2004","journal-title":"Schizophr Res"},{"key":"key\n\t\t\t\t20181017114324773_CIT0021","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1186\/s12888-016-0780-2","article-title":"Clinical correlates of vitamin D deficiency in established psychosis","volume":"16","author":"Lally","year":"2016","journal-title":"BMC Psychiatry"},{"key":"key\n\t\t\t\t20181017114324773_CIT0022","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.psychres.2016.12.052","article-title":"Correlates of vitamin D in psychotic disorders: a comprehensive systematic review","volume":"249","author":"Adamson","year":"2017","journal-title":"Psychiatry Res"},{"key":"key\n\t\t\t\t20181017114324773_CIT0023","doi-asserted-by":"crossref","DOI":"10.1038\/srep15013","article-title":"Serum trace element differences between Schizophrenia patients and controls in the Han Chinese population","volume":"5","author":"Cai","year":"2015","journal-title":"Sci Rep"},{"key":"key\n\t\t\t\t20181017114324773_CIT0024","first-page":"403","article-title":"Study of serum selenium levels in schizophrenic patients","volume-title":"Indian Medical Gazette","author":"Sharma","year":"2014"},{"key":"key\n\t\t\t\t20181017114324773_CIT0025","doi-asserted-by":"crossref","first-page":"e0133622","DOI":"10.1371\/journal.pone.0133622","article-title":"Comparative study on serum levels of 10 trace elements in schizophrenia","volume":"10","author":"Liu","year":"2015","journal-title":"PLoS One"},{"key":"key\n\t\t\t\t20181017114324773_CIT0026","doi-asserted-by":"crossref","first-page":"872","DOI":"10.1016\/j.biopsych.2013.05.008","article-title":"Zinc in depression: a meta-analysis","volume":"74","author":"Swardfager","year":"2013","journal-title":"Biol Psychiatry"},{"key":"key\n\t\t\t\t20181017114324773_CIT0027","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.ctim.2011.12.008","article-title":"Dietary selenium and major depression: a nested case\u2013control study","volume":"20","author":"Pasco","year":"2012","journal-title":"Complement Ther Med"},{"key":"key\n\t\t\t\t20181017114324773_CIT0028","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.psychres.2015.11.045","article-title":"Serum folate levels in schizophrenia: a meta-analysis","volume":"235","author":"Wang","year":"2016","journal-title":"Psychiatry Res"},{"key":"key\n\t\t\t\t20181017114324773_CIT0029","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.schres.2016.01.050","article-title":"Vitamin B12 and the risk of schizophrenia: a meta-analysis","volume":"172","author":"Cao","year":"2016","journal-title":"Schizophr Res"},{"key":"key\n\t\t\t\t20181017114324773_CIT0030","doi-asserted-by":"crossref","first-page":"3863","DOI":"10.1210\/jc.2014-1887","article-title":"Serum vitamin D levels in relation to schizophrenia: a systematic review and meta-analysis of observational studies","volume":"99","author":"Valipour","year":"2014","journal-title":"J Clin Endocrinol Metab"},{"key":"key\n\t\t\t\t20181017114324773_CIT0031","article-title":"A comparison of the nutrient intake of a community-dwelling first-episode psychosis cohort, aged 19\u201364 years, with data from the UK population","volume":"4:e28","author":"Williamson","year":"2015","journal-title":"J Nutr Sci"},{"key":"key\n\t\t\t\t20181017114324773_CIT0032","doi-asserted-by":"crossref","first-page":"1987","DOI":"10.1017\/S0007114516001033","article-title":"A nutrition intervention is effective in improving dietary components linked to cardiometabolic risk in youth with first-episode psychosis","volume":"115","author":"Teasdale","year":"2016","journal-title":"Br J Nutr"},{"key":"key\n\t\t\t\t20181017114324773_CIT0033","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/j.biopsych.2011.04.013","article-title":"Meta-analysis of cytokine alterations in schizophrenia: clinical status and antipsychotic effects","volume":"70","author":"Miller","year":"2011","journal-title":"Biol Psychiatry"},{"key":"key\n\t\t\t\t20181017114324773_CIT0034","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1016\/j.biopsych.2011.05.017","article-title":"Progressive brain change in schizophrenia: a prospective longitudinal study of first-episode schizophrenia","volume":"70","author":"Andreasen","year":"2011","journal-title":"Biol Psychiatry"},{"key":"key\n\t\t\t\t20181017114324773_CIT0035","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.schres.2010.12.008","article-title":"Cardiovascular risk in a first-episode psychosis sample: a \u2018critical period\u2019 for prevention","volume":"127","author":"Phutane","year":"2011","journal-title":"Schizophr Res"},{"key":"key\n\t\t\t\t20181017114324773_CIT0036","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1111\/eip.12251","article-title":"Antipsychotic-induced weight gain in first-episode psychosis patients: a meta-analysis of differential effects of antipsychotic medications","volume":"10","author":"Tek","year":"2016","journal-title":"Early Interv Psychiatry"},{"key":"key\n\t\t\t\t20181017114324773_CIT0037","doi-asserted-by":"crossref","first-page":"264","DOI":"10.7326\/0003-4819-151-4-200908180-00135","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"151","author":"Moher","year":"2009","journal-title":"Ann Intern Med"},{"key":"key\n\t\t\t\t20181017114324773_CIT0038","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1186\/1471-244X-4-17","article-title":"Essential elements of an early intervention service for psychosis: the opinions of expert clinicians","volume":"4","author":"Marshall","year":"2004","journal-title":"BMC Psychiatry"},{"key":"key\n\t\t\t\t20181017114324773_CIT0039","first-page":"11","article-title":"Early intervention for psychosis: the Calgary early psychosis treatment and prevention program","volume":"33","author":"Addington","year":"2001","journal-title":"Can Psychiatr Assoc Bull"},{"key":"key\n\t\t\t\t20181017114324773_CIT0040","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1136\/bmj.38246.594873.7C","article-title":"The Lambeth Early Onset (LEO) team: randomised controlled trial of the effectiveness of specialised care for early psychosis","volume":"329","author":"Craig","year":"2004","journal-title":"BMJ"},{"key":"key\n\t\t\t\t20181017114324773_CIT0041","author":"Foundation","year":"2016"},{"key":"key\n\t\t\t\t20181017114324773_CIT0042","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1093\/schbul\/sbq058","article-title":"Is abnormal glucose tolerance in antipsychotic-naive patients with nonaffective psychosis confounded by poor health habits","volume":"38","author":"Kirkpatrick","year":"2012","journal-title":"Schizophr Bull"},{"key":"key\n\t\t\t\t20181017114324773_CIT0043","article-title":"Comprehensive meta-analysis 2.0","author":"Borenstein","year":"2005","journal-title":"Biostatistics"},{"key":"key\n\t\t\t\t20181017114324773_CIT0044","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/0197-2456(86)90046-2","article-title":"Meta-analysis in clinical trials","volume":"7","author":"DerSimonian","year":"1986","journal-title":"Control Clin Trials"},{"key":"key\n\t\t\t\t20181017114324773_CIT0045","first-page":"157","article-title":"A fail-safe N for effect size in meta-analysis","volume":"8","author":"Orwin","year":"1983","journal-title":"J Educ Stat"},{"key":"key\n\t\t\t\t20181017114324773_CIT0046","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.clinbiochem.2008.04.010","article-title":"Reduced urinary excretion of homocysteine could be the reason of elevated plasma homocysteine in patients with psychiatric illnesses","volume":"41","author":"Ipcioglu","year":"2008","journal-title":"Clin Biochem"},{"key":"key\n\t\t\t\t20181017114324773_CIT0047","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1093\/schbul\/13.2.261","article-title":"The positive and negative syndrome scale (PANSS) for schizophrenia","volume":"13","author":"Kay","year":"1987","journal-title":"Schizophr Bull"},{"key":"key\n\t\t\t\t20181017114324773_CIT0048","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.schres.2014.07.033","article-title":"Serum levels of BDNF, folate and homocysteine: in relation to hippocampal volume and psychopathology in drug na\u00efve, first episode schizophrenia","volume":"159","author":"Song","year":"2014","journal-title":"Schizophr Res"},{"key":"key\n\t\t\t\t20181017114324773_CIT0049","first-page":"990","article-title":"Serum folic acid and homocysteine levels in patients with first-episode schizophrenia and their relationship with cognitive function","volume":"94","author":"Xuimei","year":"2014","journal-title":"Chin J Med Sci"},{"key":"key\n\t\t\t\t20181017114324773_CIT0050","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1007\/s00228-014-1762-2","article-title":"Effects of second-generation antipsychotics on selected markers of one-carbon metabolism and metabolic syndrome components in first-episode schizophrenia patients","volume":"70","author":"Misiak","year":"2014","journal-title":"Eur J Clin Pharmacol"},{"key":"key\n\t\t\t\t20181017114324773_CIT0051","doi-asserted-by":"crossref","first-page":"S104","DOI":"10.1016\/j.eurpsy.2016.01.086","article-title":"Methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and antipsychotic-induced metabolic disturbances in first-episode schizophrenia patients","volume":"33","author":"Misiak","year":"2016","journal-title":"Eur Psychiatry"},{"key":"key\n\t\t\t\t20181017114324773_CIT0052","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.psychres.2009.01.013","article-title":"Reduced folic acid, vitamin B12 and docosahexaenoic acid and increased homocysteine and cortisol in never-medicated schizophrenia patients: Implications for altered one-carbon metabolism","volume":"175","author":"Kale","year":"2010","journal-title":"Psychiatry Res"},{"key":"key\n\t\t\t\t20181017114324773_CIT0053","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1007\/s11011-014-9534-3","article-title":"Elevated homocysteine level in first-episode schizophrenia patients\u2014the relevance of family history of schizophrenia and lifetime diagnosis of cannabis abuse","volume":"29","author":"Misiak","year":"2014","journal-title":"Metab Brain Dis"},{"key":"key\n\t\t\t\t20181017114324773_CIT0054","doi-asserted-by":"crossref","first-page":"1370","DOI":"10.12669\/pjms.326.11157","article-title":"1, 25-dihydroxyvitamin D3, a potential role player in the development of thyroid disorders in schizophrenics","volume":"32","author":"Malik","year":"2016","journal-title":"Pak J Med Sci"},{"key":"key\n\t\t\t\t20181017114324773_CIT0055","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1016\/j.psychres.2015.10.015","article-title":"Vitamin D status in psychotic disorder patients and healthy controls\u2014the influence of ethnic background","volume":"230","author":"Nerhus","year":"2015","journal-title":"Psychiatry Res"},{"key":"key\n\t\t\t\t20181017114324773_CIT0056","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1097\/NMD.0000000000000670","article-title":"Association between vitamin D status and schizophrenia: a first psychotic episode study","volume":"205","author":"Salavert","year":"2017","journal-title":"J Nerv Ment Dis"},{"key":"key\n\t\t\t\t20181017114324773_CIT0057","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1111\/eip.12122","article-title":"Relationship of low vitamin D status with positive, negative and cognitive symptom domains in people with first-episode schizophrenia","volume":"9","author":"Graham","year":"2015","journal-title":"Early Interv Psychiatry"},{"key":"key\n\t\t\t\t20181017114324773_CIT0058","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.psychres.2016.07.003","article-title":"Association between serum levels of bioavailable vitamin D and negative symptoms in first-episode psychosis","volume":"243","author":"Yee","year":"2016","journal-title":"Psychiatry Res"},{"key":"key\n\t\t\t\t20181017114324773_CIT0059","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1007\/BF02912908","article-title":"Oxidative stress, \u03b1-tocopherol, ascorbic acid and reduced glutathione status in schizophrenics","volume":"21","author":"Dadheech","year":"2006","journal-title":"Indian J Clin Biochem"},{"key":"key\n\t\t\t\t20181017114324773_CIT0060","first-page":"39","article-title":"Status of lipid peroxidation, glutathione, ascorbic acid, vitamin E and antioxidant enzymes in schizophrenic patients","volume":"1","author":"Surapaneni","year":"2007","journal-title":"J Clin Diagn Res"},{"key":"key\n\t\t\t\t20181017114324773_CIT0061","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1192\/bjp.176.3.290","article-title":"Smoking habits and plasma lipid peroxide and vitamin E levels in never-treated first-episode patients with schizophrenia","volume":"176","author":"Scottish Schizophrenia Research Group","year":"2000","journal-title":"Br J Psychiatry"},{"key":"key\n\t\t\t\t20181017114324773_CIT0062","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1007\/s00213-005-0117-1","article-title":"Supplementation of vitamin C with atypical antipsychotics reduces oxidative stress and improves the outcome of schizophrenia","volume":"182","author":"Dakhale","year":"2005","journal-title":"Psychopharmacology (Berl)"},{"key":"key\n\t\t\t\t20181017114324773_CIT0063","first-page":"259","article-title":"Serum copeptin and its diagnostic performance in schizophrenia","volume":"43","author":"Akinladel","year":"2014","journal-title":"Afr J Med Med Sci"},{"key":"key\n\t\t\t\t20181017114324773_CIT0064","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.2174\/1871527314666150317225828","article-title":"Association of single nucleotide polymorphisms in catechol-omethyltransferase and serine-threonine protein kinase genes in the Pakistani schizophrenic population: a study with special emphasis on cannabis and smokeless tobacco","volume":"14","author":"Nawaz","year":"2015","journal-title":"CNS Neurol Disord Drug Targets"},{"key":"key\n\t\t\t\t20181017114324773_CIT0065","first-page":"1","article-title":"Essential trace metals and heavy metals in newly diagnosed schizophrenic patients and those on anti-psychotic medication","volume":"15","author":"Arinola","year":"2010","journal-title":"J Res Med Sci"},{"key":"key\n\t\t\t\t20181017114324773_CIT0066","doi-asserted-by":"crossref","first-page":"549S","DOI":"10.1080\/07315724.2004.10719401","article-title":"The influence of some antipsychotics on erythrocyte magnesium and plasma magnesium, calcium, copper and zinc in patients with paranoid schizophrenia","volume":"23","author":"Nechifor","year":"2004","journal-title":"J Am Coll Nutr"},{"key":"key\n\t\t\t\t20181017114324773_CIT0067","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.1093\/schbul\/sbq101","article-title":"Developmental vitamin D deficiency and risk of schizophrenia: a 10-year update","volume":"36","author":"McGrath","year":"2010","journal-title":"Schizophr Bull"},{"key":"key\n\t\t\t\t20181017114324773_CIT0068","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1093\/ajcn\/85.3.860","article-title":"Hypovitaminosis D in British adults at age 45 y: nationwide cohort study of dietary and lifestyle predictors","volume":"85","author":"Hypp\u00f6nen","year":"2007","journal-title":"Am J Clin Nutr"},{"key":"key\n\t\t\t\t20181017114324773_CIT0069","doi-asserted-by":"crossref","DOI":"10.1111\/j.1753-4887.2008.00100.x","article-title":"Vitamin D deficiency: a global perspective","volume":"66","author":"Prentice","year":"2008","journal-title":"Nutr Rev"},{"key":"key\n\t\t\t\t20181017114324773_CIT0070","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1212\/WNL.0b013e31826c197f","article-title":"Vitamin D, cognition, and dementia: a systematic review and meta-analysis","volume":"79","author":"Balion","year":"2012","journal-title":"Neurology"},{"key":"key\n\t\t\t\t20181017114324773_CIT0071","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.plipres.2011.05.001","article-title":"Vitamin D and metabolic health with special reference to the effect of vitamin D on serum lipids","volume":"50","author":"Jorde","year":"2011","journal-title":"Prog Lipid Res"},{"key":"key\n\t\t\t\t20181017114324773_CIT0072","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.pscychresns.2015.06.006","article-title":"Serum vitamin D and hippocampal gray matter volume in schizophrenia","volume":"233","author":"Shivakumar","year":"2015","journal-title":"Psychiatry Res"},{"key":"key\n\t\t\t\t20181017114324773_CIT0073","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1159\/000371618","article-title":"The epidemiology of global micronutrient deficiencies","volume":"66","author":"Bailey","year":"2015","journal-title":"Ann Nutr Metab"},{"key":"key\n\t\t\t\t20181017114324773_CIT0074","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1016\/j.molmed.2009.10.001","article-title":"One-carbon metabolism and schizophrenia: current challenges and future directions","volume":"15","author":"Krebs","year":"2009","journal-title":"Trends Mol Med"},{"key":"key\n\t\t\t\t20181017114324773_CIT0075","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.schres.2010.12.006","article-title":"Folate supplementation in schizophrenia: a possible role for MTHFR genotype","volume":"127","author":"Hill","year":"2011","journal-title":"Schizophr Res"},{"key":"key\n\t\t\t\t20181017114324773_CIT0076","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1001\/jamapsychiatry.2013.900","article-title":"Randomized multicenter investigation of folate plus vitamin B12 supplementation in schizophrenia","volume":"70","author":"Roffman","year":"2013","journal-title":"JAMA Psychiatry"},{"key":"key\n\t\t\t\t20181017114324773_CIT0077","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1176\/appi.ajp.2012.11071114","article-title":"L-methylfolate as adjunctive therapy for SSRI-resistant major depression: results of two randomized, double-blind, parallel-sequential trials","volume":"169","author":"Papakostas","year":"2012","journal-title":"Am J Psychiatry"},{"key":"key\n\t\t\t\t20181017114324773_CIT0078","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/BF03324128","article-title":"Oral 5\u2032-methyltetrahydrofolic acid in senile organic mental disorders with depression: results of a double-blind multicenter study","volume":"5","author":"Passen","year":"1993","journal-title":"Aging Clin Exp Res"},{"key":"key\n\t\t\t\t20181017114324773_CIT0079","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1136\/bmj.317.7161.784","article-title":"Dietary intake of schizophrenic patients in Nithsdale, Scotland: case\u2013control study","volume":"317","author":"McCreadie","year":"1998","journal-title":"BMJ"},{"key":"key\n\t\t\t\t20181017114324773_CIT0080","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1111\/acps.12708","article-title":"Vitamin D and mental health\u2014the scrutiny of science delivers a sober message","volume":"135","author":"McGrath","year":"2017","journal-title":"Acta Psychiatr Scand"},{"key":"key\n\t\t\t\t20181017114324773_CIT0081","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1038\/bjc.2014.294","article-title":"Vitamin D supplements and cancer incidence and mortality: a meta-analysis","volume":"111","author":"Keum","year":"2014","journal-title":"Br J Cancer"},{"key":"key\n\t\t\t\t20181017114324773_CIT0082","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1001\/jama.2012.120","article-title":"Vitamin D therapy and cardiac structure and function in patients with chronic kidney disease: the PRIMO randomized controlled trial","volume":"307","author":"Thadhani","year":"2012","journal-title":"JAMA"},{"key":"key\n\t\t\t\t20181017114324773_CIT0083","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.biopsych.2008.03.004","article-title":"N-acetyl cysteine as a glutathione precursor for schizophrenia\u2013a double-blind, randomized, placebo-controlled trial","volume":"64","author":"Berk","year":"2008","journal-title":"Biol Psychiatry"},{"key":"key\n\t\t\t\t20181017114324773_CIT0084","doi-asserted-by":"crossref","first-page":"e1610","DOI":"10.4088\/JCP.15m10185","article-title":"Adjunctive taurine in first-episode psychosis: a phase 2, double-blind, randomized, placebo-controlled study","volume":"77","author":"O\u2019Donnell","year":"2016","journal-title":"J Clin Psychiatry"},{"key":"key\n\t\t\t\t20181017114324773_CIT0085","article-title":"Solving a weighty problem: systematic review and meta-analysis of nutrition interventions in severe mental illness","author":"Teasdale","year":"2016","journal-title":"Br J Psychiatry"},{"key":"key\n\t\t\t\t20181017114324773_CIT0086","doi-asserted-by":"crossref","first-page":"3258","DOI":"10.1001\/archinte.160.21.3258","article-title":"Serum folate and cardiovascular disease mortality among US men and women","volume":"160","author":"Loria","year":"2000","journal-title":"Arch Intern Med"},{"key":"key\n\t\t\t\t20181017114324773_CIT0087","doi-asserted-by":"crossref","first-page":"g3656","DOI":"10.1136\/bmj.g3656","article-title":"Vitamin D and mortality: meta-analysis of individual participant data from a large consortium of cohort studies from Europe and the United States","volume":"348","author":"Sch\u00f6ttker","year":"2014","journal-title":"BMJ"},{"key":"key\n\t\t\t\t20181017114324773_CIT0088","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.aimed.2015.02.001","article-title":"An adjunctive antidepressant nutraceutical combination in treating major depression: study protocol, and clinical considerations","volume":"7","author":"Sarris","year":"2015","journal-title":"Adv Integr Med"},{"key":"key\n\t\t\t\t20181017114324773_CIT0089","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1590\/1516-4446-2013-1341","article-title":"Design and rationale of a 16-week adjunctive randomized placebo-controlled trial of mitochondrial agents for the treatment of bipolar depression","volume":"37","author":"Dean","year":"2015","journal-title":"Rev Bras Psiquiatr"},{"key":"key\n\t\t\t\t20181017114324773_CIT0090","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1007\/s00406-012-0302-2","article-title":"Homocysteine and cognition in first-episode psychosis patients","volume":"262","author":"Ayesa-Arriola","year":"2012","journal-title":"European Archives of Psychiatry and Clinical Neuroscience"},{"key":"key\n\t\t\t\t20181017114324773_CIT0091","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/j.genhosppsych.2015.03.017","article-title":"The history of childhood trauma is associated with lipid disturbances and blood pressure in adult first-episode schizophrenia patients","volume":"37","author":"Misiak","year":"2015","journal-title":"General Hospital Psychiatry"},{"key":"key\n\t\t\t\t20181017114324773_CIT0092","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1016\/j.schres.2013.08.036","article-title":"Vitamin D deficiency in first episode psychosis: a case\u2013control study","volume":"150","author":"Crews","year":"2013","journal-title":"Schizophrenia research"},{"key":"key\n\t\t\t\t20181017114324773_CIT0093","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1016\/j.psychres.2015.05.051","article-title":"High levels of vitamin D in relation to reduced risk of schizophrenia with elevated C-reactive protein","volume":"228","author":"Zhu","year":"2015","journal-title":"Psychiatry Research"},{"key":"key\n\t\t\t\t20181017114324773_CIT0094","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1111\/pcn.12333","article-title":"First\u2010episode psychosis is associated with oxidative stress: effects of short\u2010term antipsychotic treatment","volume":"69","author":"Sarandol","year":"2015","journal-title":"Psychiatry and Clinical Neurosciences"},{"key":"key\n\t\t\t\t20181017114324773_CIT0095","first-page":"37","article-title":"Status of plasma nitric oxide and non-enzymatic antioxidants before and after antipsychotic treatment in Nigerian patients with schizophrenia","volume":"14","author":"Arinola","year":"2009","journal-title":"Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences"},{"key":"key\n\t\t\t\t20181017114324773_CIT0096","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.pscychresns.2006.12.006","article-title":"CSF sub-compartments in relation to plasma osmolality in healthy controls and in patients with first episode schizophrenia","volume":"155","author":"Gunduz-Bruce","year":"2007","journal-title":"Psychiatry Research: Neuroimaging"},{"key":"key\n\t\t\t\t20181017114324773_CIT0097","doi-asserted-by":"crossref","first-page":"450","DOI":"10.4236\/wjns.2014.45051","article-title":"The role of trace metals and environmental factors in the onset and progression of schizophrenia in Pakistani population","volume":"4","author":"Nawaz","year":"2014","journal-title":"World Journal of Neuroscience"},{"key":"key\n\t\t\t\t20181017114324773_CIT0098","first-page":"19","article-title":"Inter-relationship of circulating biochemical markers of oxidative stress and thyroid hormones in newly diagnosed schizophrenics: perspective study from local population of Punjab pakistan","volume":"25","author":"Jamil","year":"2014","journal-title":"Medical Forum"}],"container-title":["Schizophrenia Bulletin"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/schizophreniabulletin\/article-pdf\/44\/6\/1275\/26088304\/sbx162.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,10,5]],"date-time":"2019-10-05T03:23:22Z","timestamp":1570245802000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/schizophreniabulletin\/article\/44\/6\/1275\/4675234"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,30]]},"references-count":98,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2017,11,30]]},"published-print":{"date-parts":[[2018,10,17]]}},"URL":"https:\/\/doi.org\/10.1093\/schbul\/sbx162","relation":{},"ISSN":["0586-7614","1745-1701"],"issn-type":[{"value":"0586-7614","type":"print"},{"value":"1745-1701","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,11]]},"published":{"date-parts":[[2017,11,30]]}}}