{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T17:55:22Z","timestamp":1789754122117,"version":"4.0.1"},"reference-count":98,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,7,27]],"date-time":"2024-07-27T00:00:00Z","timestamp":1722038400000},"content-version":"vor","delay-in-days":208,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background and Hypothesis<\/jats:title>\n                    <jats:p>The clinical-high-risk (CHR) approach was developed to prevent psychosis through the detection of psychosis risk. CHR services are transdiagnostic in nature, therefore the appropriate management of comorbidity is a central part of care. Differential diagnosis is particularly challenging across 3 common comorbidities, schizotypal personality disorder (SPD), autism spectrum disorder (ASD), and borderline personality disorder (BPD). Phenomenological research indicates a disturbance of \u201cbasic self\u201d may differentiate between these commonly comorbid disorders and can be captured by Huber\u2019s basic symptoms (BS) concept. We investigated whether BS vary across these disorders and may inform differential diagnosis in young person\u2019s meeting CHR criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design<\/jats:title>\n                    <jats:p>A total of 685 participants meeting CHR criteria from the NAPLS-3 cohort completed the COGDIS items of the schizophrenia proneness instrument, a measure of BS, as well as the structured interview for DSM-5 (SCID-5). A logistic regression model was used to investigate the variation of COGDIS across SPD, ASD, and BPD, while controlling for age and SIPs positive severity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Results<\/jats:title>\n                    <jats:p>Meeting COGDIS criteria was positively associated with SPD (OR\u2005=\u20051.72, CI\u2005=\u2005[1.31\u20132.28], P\u2005=\u2005.001) but not ASD nor BPD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Our results indicate that \u201cbasic self-disturbance\u201d as indicated by COGDIS differs across SPD, ASD, and BPD. COGDIS may be useful to inform the management of comorbidities in CHR services, by providing insight into subtle subjective experiences that may benefit from disorder-specific interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/schizbullopen\/sgae017","type":"journal-article","created":{"date-parts":[[2024,7,27]],"date-time":"2024-07-27T04:48:40Z","timestamp":1722055720000},"source":"Crossref","is-referenced-by-count":13,"title":["A Tale of Three Spectra: Basic Symptoms in Clinical-High-Risk of Psychosis Vary Across Autism Spectrum Disorder, Schizotypal Personality Disorder, and Borderline Personality Disorder"],"prefix":"10.1093","volume":"5","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-5930-4141","authenticated-orcid":false,"given":"James C","family":"Martin","sequence":"first","affiliation":[{"name":"Discipline of Psychiatry, Adelaide Medical School, The University of Adelaide , North Terrace, Adelaide, South Australia , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Scott R","family":"Clark","sequence":"additional","affiliation":[{"name":"Discipline of Psychiatry, Adelaide Medical School, The University of Adelaide , North Terrace, Adelaide, South Australia , Australia"},{"name":"Discipline of Psychiatry, Basil Hetzel Institute , Woodville, South Australia , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Hartmann","sequence":"additional","affiliation":[{"name":"Discipline of Psychiatry, Adelaide Medical School, The University of Adelaide , North Terrace, Adelaide, South Australia , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K Oliver","family":"Schubert","sequence":"additional","affiliation":[{"name":"Discipline of Psychiatry, Adelaide Medical School, The University of Adelaide , North Terrace, Adelaide, South Australia , Australia"},{"name":"Division of Mental Health, Northern Adelaide Local Health 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