{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:42:46Z","timestamp":1787499766453,"version":"build-2736575974"},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T00:00:00Z","timestamp":1737504000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,3,18]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Fixed drug eruption (FDE) is a distinct adverse drug reaction characterized by a well-defined, dusky, violaceous to erythematous patch that recurs at the same site upon re-exposure to causative drugs and resolves with hyperpigmentation. This unique reaction is a type IV hypersensitivity reaction mediated by memory CD8+ T cells that reside in the basal layer of the epidermis of the resting FDE lesion. Variants of FDE described in the literature include bullous, generalized bullous, nonpigmenting, linear, papular, erythema multiforme-like, transitory giant, annular, psoriasiform, erythema dyschromicum perstans-like and cellulitis-like. We present the case of a 12-year-old boy with FDE in a cribriform pattern that has not been defined so far.<\/jats:p>","DOI":"10.1093\/skinhd\/vzae006","type":"journal-article","created":{"date-parts":[[2025,1,22]],"date-time":"2025-01-22T11:01:28Z","timestamp":1737543688000},"page":"50-52","source":"Crossref","is-referenced-by-count":2,"title":["Fixed drug eruption in a cribriform pattern: an atypical presentation"],"prefix":"10.1093","volume":"5","author":[{"given":"Mahesh","family":"Mathur","sequence":"first","affiliation":[{"name":"Department of Dermatology, College of Medical Sciences Teaching Hospital , Bharatpur ,","place":["Nepal"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neha","family":"Thakur","sequence":"additional","affiliation":[{"name":"Department of Dermatology, College of Medical Sciences Teaching Hospital , Bharatpur ,","place":["Nepal"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-5844-8910","authenticated-orcid":false,"given":"Sandhya","family":"Regmi","sequence":"additional","affiliation":[{"name":"Department of Dermatology, College of Medical Sciences Teaching Hospital , Bharatpur ,","place":["Nepal"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-2177-8995","authenticated-orcid":false,"given":"Supriya","family":"Paudel","sequence":"additional","affiliation":[{"name":"Department of Dermatology, College of Medical Sciences Teaching Hospital , Bharatpur ,","place":["Nepal"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-2859-0376","authenticated-orcid":false,"given":"Nabita","family":"Bhattarai","sequence":"additional","affiliation":[{"name":"Department of Dermatology, College of Medical Sciences Teaching Hospital , Bharatpur ,","place":["Nepal"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sambidha","family":"Karki","sequence":"additional","affiliation":[{"name":"Department of Dermatology, College of Medical Sciences Teaching Hospital , Bharatpur ,","place":["Nepal"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,1,22]]},"reference":[{"key":"2025090300365565600_vzae006-B1","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1007\/s40257-020-00505-3","article-title":"Fixed drug eruptions: an update, emphasizing the potentially lethal generalized bullous fixed drug eruption","volume":"21","author":"Patel","year":"2020","journal-title":"Am J Clin Dermatol"},{"key":"2025090300365565600_vzae006-B2","doi-asserted-by":"crossref","first-page":"277","DOI":"10.2165\/00128071-200001050-00003","article-title":"Fixed drug eruptions. Incidence, recognition, and avoidance","volume":"1","author":"Lee","year":"2000","journal-title":"Am J Clin Dermatol"},{"key":"2025090300365565600_vzae006-B3","doi-asserted-by":"crossref","first-page":"925","DOI":"10.3390\/medicina57090925","article-title":"A review of fixed drug eruption with a special focus on generalized bullous fixed drug eruption","volume":"57","author":"Anderson","year":"2021","journal-title":"Medicina (Kaunas)"},{"key":"2025090300365565600_vzae006-B4","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1016\/S0091-6749(03)01624-5","article-title":"IFN-gamma-producing effector CD8+ T cells and IL-10-producing regulatory CD4+ T cells in fixed drug eruption","volume":"112","author":"Teraki","year":"2003","journal-title":"J Allergy Clin Immunol"},{"key":"2025090300365565600_vzae006-B5","doi-asserted-by":"crossref","first-page":"475","DOI":"10.25259\/IJDVL_502_2021","article-title":"Uncommon variants of fixed drug eruption","volume":"89","author":"Agarwal","year":"2023","journal-title":"Indian J Dermatol Venereol Leprol"}],"container-title":["Skin Health and Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/skinhd\/article-pdf\/5\/1\/50\/61559651\/vzae006.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/skinhd\/article-pdf\/5\/1\/50\/61559651\/vzae006.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T04:37:04Z","timestamp":1756874224000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/skinhd\/article\/5\/1\/50\/7972520"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,22]]},"references-count":5,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2025,1,22]]},"published-print":{"date-parts":[[2025,3,18]]}},"URL":"https:\/\/doi.org\/10.1093\/skinhd\/vzae006","relation":{},"ISSN":["2690-442X"],"issn-type":[{"value":"2690-442X","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,2]]},"published":{"date-parts":[[2025,1,22]]}}}