{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T05:01:49Z","timestamp":1793509309340,"version":"4.5.0"},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T00:00:00Z","timestamp":1773964800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,31]]},"abstract":"<jats:p>The pathogenic role of commensal Demodex mites in lichen planopilaris remains hypothetical. We propose a multifactorial model where mite lipases and antigens disrupt follicular peroxisome proliferator-activated receptor gamma (PPAR-\u03b3) signalling and trigger a lymphocytic response that may progress to autoimmunity. A therapeutic paradox exists, as immunomodulatory treatments may reduce inflammation but also promote mite proliferation, underscoring the need for controlled trials.<\/jats:p>","DOI":"10.1093\/skinhd\/vzag015","type":"journal-article","created":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T09:05:32Z","timestamp":1773997532000},"page":"619-621","source":"Crossref","is-referenced-by-count":1,"title":["Is\n                    <i>Demodex<\/i>\n                    hiding in lichen planopilaris pathogenesis? The trichoscopy-blind zone"],"prefix":"10.1093","volume":"6","author":[{"given":"Kambiz","family":"Kamyab Hesari","sequence":"first","affiliation":[{"name":"Department of Dermatopathology, Razi Hospital, Tehran University of Medical Sciences , Tehran ,","place":["Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alireza","family":"Ghanadan","sequence":"additional","affiliation":[{"name":"Department of Dermatopathology, Razi Hospital, Tehran University of Medical Sciences , Tehran ,","place":["Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vahidehsadat","family":"Azhari","sequence":"additional","affiliation":[{"name":"Department of Dermatopathology, Razi Hospital, Tehran University of Medical Sciences , Tehran ,","place":["Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahar","family":"Montazeri","sequence":"additional","affiliation":[{"name":"Department of Dermatopathology, Razi Hospital, Tehran University of Medical 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