{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T09:58:10Z","timestamp":1785491890400,"version":"3.56.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T00:00:00Z","timestamp":1777420800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007833","name":"Hamad Medical Corporation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007833","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020643","name":"Medical Research Center","doi-asserted-by":"publisher","award":["MRC-04-25-790"],"award-info":[{"award-number":["MRC-04-25-790"]}],"id":[{"id":"10.13039\/501100020643","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100019779","name":"Qatar National Library","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100019779","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Chronic prurigo, formerly termed prurigo nodularis, is a chronic skin condition characterized by intensely itchy nodules and papules. It primarily affects adults, particularly middle-aged women. The aetiology of chronic prurigo is unclear, but it can be associated with primary skin dermatoses and systemic conditions. Minimal data on chronic prurigo in children are available in the literature. While systemic therapies for chronic prurigo have significant side effects, targeted biologic and small-\u00admolecule inhibitors offer a promising treatment option with a good benefit\u2013risk ratio. We report one of the first cases of an adolescent with chronic prurigo that was successfully controlled with dupilumab. Dupilumab treatment resulted in a fast, significant and sustainable improvement in the signs and symptoms of chronic prurigo, with favourable safety and tolerability profiles, highlighting its potential for recalcitrant cases and long-term remission.<\/jats:p>","DOI":"10.1093\/skinhd\/vzag050","type":"journal-article","created":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T15:53:45Z","timestamp":1773330825000},"page":"582-585","source":"Crossref","is-referenced-by-count":0,"title":["Chronic prurigo in an adolescent patient successfully controlled with dupilumab"],"prefix":"10.1093","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-3048-6213","authenticated-orcid":false,"given":"Mohammed Nasser","family":"Al-Abdulla","sequence":"first","affiliation":[{"name":"Department of Dermatology and Venereology, Hamad Medical Corporation , Doha ,","place":["Qatar"]},{"name":"Dermatology Institute, Hamad Medical Corporation , Doha ,","place":["Qatar"]},{"name":"Translational Research Institute, Academic Health System, Hamad Medical Corporation , Doha ,","place":["Qatar"]},{"name":"Weill Cornell Medicine-Qatar, School of Medicine , Doha ,","place":["Qatar"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noof","family":"Al-Qahtani","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Venereology, Hamad Medical Corporation , Doha ,","place":["Qatar"]},{"name":"College of Medicine, Qatar University , Doha ,","place":["Qatar"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shahd M","family":"Younis","sequence":"additional","affiliation":[{"name":"Translational Research Institute, Academic Health System, Hamad Medical Corporation , Doha ,","place":["Qatar"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed","family":"Rizvi","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine and Pathology, Hamad Medical Corporation , Doha 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Corporation , Doha ,","place":["Qatar"]},{"name":"Translational Research Institute, Academic Health System, Hamad Medical Corporation , Doha ,","place":["Qatar"]},{"name":"Weill Cornell Medicine-Qatar, School of Medicine , Doha ,","place":["Qatar"]},{"name":"College of Medicine, Qatar University , Doha ,","place":["Qatar"]},{"name":"Department of Dermatology, Weill Cornell Medicine , New York, NY ,","place":["USA"]},{"name":"School of Life Sciences, Hamad-bin-Khalifa University , Doha ,","place":["Qatar"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,4,29]]},"reference":[{"key":"2026073105074395000_vzag050-B1","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.jid.2019.07.697","article-title":"Real-world prevalence of prurigo nodularis and burden of associated diseases","volume":"140","author":"Huang","year":"2020","journal-title":"J Invest 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