{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T09:58:21Z","timestamp":1785491901193,"version":"3.56.0"},"reference-count":34,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T00:00:00Z","timestamp":1779753600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Backround<\/jats:title>\n                    <jats:p>Facial atrophic scars significantly impact self-confidence and quality of life. Recently, the combination of \u00adplatelet-rich plasma (PRP) and subcision has been proposed as a potential treatment modality; however, clinical trial results remain inconsistent.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To assess the clinical efficacy and safety of combining subcision with PRP therapy for the treatment of facial atrophic acne scars in Vietnamese patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 44 patients with facial atrophic scars of grade 2 or higher were included in the study. Each patient underwent three treatment sessions using a combination of subcision and PRP at 4-week intervals. The patients were evaluated by three independent reviewers through a series of sequential photographs taken 1 month after the third treatment session.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>All patients presented with atrophic scars on the cheeks, predominantly mixed scars caused by acne (96%). At evaluation timepoints, the Goodman and Baron grading scale demonstrated significant improvement, with statistically significant differences (P &amp;lt; 0.05). Following the treatment regimen of subcision combined with PRP, the majority of patients achieved good-to-excellent responses (96%) and reported satisfaction with the treatment outcomes (96%). Common side effects included pain (93%), mild swelling (41%) and erythema (34%), all of which were transient. The baseline severity of scars (Goodman and Baron) and the presence of rolling scars significantly influenced treatment efficacy (P &amp;lt; 0.05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The combination of subcision and PRP is an effective and safe approach for the treatment of atrophic scars, providing significant improvement and high patient satisfaction.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/skinhd\/vzag053","type":"journal-article","created":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T12:41:38Z","timestamp":1773578498000},"page":"477-484","source":"Crossref","is-referenced-by-count":0,"title":["Treatment outcomes using subcision combined with platelet-rich plasma for atrophic acne scars: a study in Vietnamese patients"],"prefix":"10.1093","volume":"6","author":[{"given":"Lam Van","family":"Nguyen","sequence":"first","affiliation":[{"name":"Department of Plastic and Aesthetic Surgery, Faculty of Medicine, Can Tho University of Medicine and Pharmacy , Can Tho City ,","place":["Vietnam"]},{"name":"Centre for Cosmetic Surgery and Skin Care, Can Tho University of Medicine and Pharmacy Hospital , Can Tho City ,","place":["Vietnam"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tan Tan","family":"Lam","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Nam Can Tho University , Can Tho City ,","place":["Vietnam"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,5,26]]},"reference":[{"key":"2026073105085538000_vzag053-B1","doi-asserted-by":"crossref","first-page":"137","DOI":"10.4103\/JCAS.JCAS_64_23","article-title":"PRP and its benefit as an adjunctive therapy with subcision and microneedling in atrophic scars: a comparative 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