{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T00:08:14Z","timestamp":1790122094473,"version":"4.0.1"},"reference-count":48,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2021,9,22]],"date-time":"2021-09-22T00:00:00Z","timestamp":1632268800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"EU H2020 Virtual Brain Cloud","award":["826421"],"award-info":[{"award-number":["826421"]}]},{"name":"Italian Ministry of Health - Italian Neuroscience"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,1,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Study Objectives<\/jats:title>\n                    <jats:p>Increased phase synchronization in electroencephalography (EEG) bands might reflect the activation of compensatory mechanisms of cognitive decline in people with neurodegenerative diseases. Here, we investigated whether altered large-scale couplings of brain oscillations could be linked to the balancing of cognitive decline in a longitudinal cohort of people with idiopathic rapid eye-movement sleep behavior disorder (iRBD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We analyzed 18 patients (17 males, 69.7 \u00b1 7.5 years) with iRBD undergoing high-density EEG (HD-EEG), presynaptic dopaminergic imaging, and clinical and neuropsychological (NPS) assessments at two time points (time interval 24.2 \u00b1 5.9 months). We thus quantified the HD-EEG power distribution, orthogonalized amplitude correlation, and weighted phase-lag index at both time points and correlated them with clinical, NPS, and imaging data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Four patients phenoconverted at follow-up (three cases of parkinsonism and one of dementia). At the group level, NPS scores decreased over time, without reaching statistical significance. However, alpha phase synchronization increased and delta amplitude correlations decreased significantly at follow-up compared to baseline. Both large-scale network connectivity metrics were significantly correlated with NPS scores but not with sleep quality indices or presynaptic dopaminergic imaging data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>These results suggest that increased alpha phase synchronization and reduced delta amplitude correlation may be considered electrophysiological signs of an active compensatory mechanism of cognitive impairment in people with iRBD. Large-scale functional modifications may be helpful biomarkers in the characterization of prodromal stages of alpha-synucleinopathies.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/sleep\/zsab232","type":"journal-article","created":{"date-parts":[[2021,9,22]],"date-time":"2021-09-22T15:23:18Z","timestamp":1632324198000},"source":"Crossref","is-referenced-by-count":21,"title":["Phase and amplitude electroencephalography correlations change with disease progression in people with idiopathic rapid eye-movement sleep behavior disorder"],"prefix":"10.1093","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4522-1574","authenticated-orcid":false,"given":"Monica","family":"Roascio","sequence":"first","affiliation":[{"name":"Department of Informatics, Bioengineering, Robotics and System engineering (DIBRIS), University of Genoa , Genoa , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8946-5290","authenticated-orcid":false,"given":"Andrea","family":"Canessa","sequence":"additional","affiliation":[{"name":"Department of Informatics, Bioengineering, Robotics and System engineering (DIBRIS), University of Genoa , Genoa , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4915-5295","authenticated-orcid":false,"given":"Rosella","family":"Tr\u00f2","sequence":"additional","affiliation":[{"name":"Department of Informatics, Bioengineering, Robotics and System engineering (DIBRIS), University of Genoa , Genoa , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pietro","family":"Mattioli","sequence":"additional","affiliation":[{"name":"Clinical Neurology, Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Children\u2019s Sciences (DINOGMI), University of Genoa , Genoa , Italy"},{"name":"IRCCS Ospedale Policlinico San Martino , Genoa , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francesco","family":"Fam\u00e0","sequence":"additional","affiliation":[{"name":"Clinical Neurology, Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Children\u2019s Sciences (DINOGMI), University of Genoa , Genoa , Italy"},{"name":"IRCCS Ospedale Policlinico San Martino , Genoa , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Giorgetti","sequence":"additional","affiliation":[{"name":"IRCCS Ospedale Policlinico San Martino , Genoa , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicola","family":"Girtler","sequence":"additional","affiliation":[{"name":"Clinical Neurology, Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Children\u2019s Sciences (DINOGMI), University of Genoa , Genoa , Italy"},{"name":"IRCCS Ospedale Policlinico San Martino , Genoa , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatrice","family":"Orso","sequence":"additional","affiliation":[{"name":"Clinical Neurology, Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Children\u2019s Sciences (DINOGMI), University of Genoa , Genoa , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Morbelli","sequence":"additional","affiliation":[{"name":"IRCCS Ospedale Policlinico San Martino , Genoa , Italy"},{"name":"Nuclear Medicine, Department of Health Sciences (DISSAL), University of Genoa , Genoa , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavio","family":"Nobili","sequence":"additional","affiliation":[{"name":"Clinical Neurology, Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Children\u2019s Sciences (DINOGMI), University of Genoa , Genoa , Italy"},{"name":"IRCCS Ospedale Policlinico San Martino , Genoa , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6823-6069","authenticated-orcid":false,"given":"Dario","family":"Arnaldi","sequence":"additional","affiliation":[{"name":"Clinical Neurology, Department of Neurosciences, Rehabilitation, Ophthalmology, Genetics, Maternal and Children\u2019s Sciences (DINOGMI), University of Genoa , Genoa , Italy"},{"name":"IRCCS Ospedale Policlinico San Martino , Genoa , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1140-0320","authenticated-orcid":false,"given":"Gabriele","family":"Arnulfo","sequence":"additional","affiliation":[{"name":"Department of Informatics, Bioengineering, Robotics and System engineering (DIBRIS), University of Genoa , Genoa , Italy"},{"name":"Neuroscience Center, Helsinki Institute of Life Science (HiLife), University of Helsinki , Helsinki , Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2021,9,22]]},"reference":[{"issue":"2","key":"2023120718561470200_CIT0001","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1093\/sleep\/9.2.293","article-title":"Chronic behavioral disorders of human REM sleep: a new category of parasomnia","volume":"9","author":"Schenck","year":"1986","journal-title":"Sleep."},{"issue":"5","key":"2023120718561470200_CIT0002","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1002\/mds.27018","article-title":"REM sleep behavior disorder in Parkinson\u2019s disease and other synucleinopathies","volume":"32","author":"St Louis","year":"2017","journal-title":"Mov Disord."},{"issue":"1","key":"2023120718561470200_CIT0003","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1093\/brain\/awaa365","article-title":"Dopaminergic imaging and clinical predictors for phenoconversion of REM sleep behaviour disorder","volume":"144","author":"Arnaldi","year":"2021","journal-title":"Brain."},{"issue":"3","key":"2023120718561470200_CIT0004","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1093\/brain\/awz030","article-title":"Risk and predictors of dementia and parkinsonism in idiopathic REM sleep behaviour disorder: a multicentre study","volume":"142","author":"Postuma","year":"2019","journal-title":"Brain."},{"issue":"5","key":"2023120718561470200_CIT0005","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1002\/ana.22282","article-title":"Olfaction and color vision identify impending neurodegeneration in rapid eye movement sleep behavior disorder","volume":"69","author":"Postuma","year":"2011","journal-title":"Ann Neurol."},{"issue":"9","key":"2023120718561470200_CIT0006","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.2967\/jnumed.117.202242","article-title":"The metabolic pattern of idiopathic REM sleep behavior disorder reflects early-stage Parkinson disease","volume":"59","author":"Meles","year":"2018","journal-title":"J Nucl Med."},{"issue":"6","key":"2023120718561470200_CIT0007","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1002\/ana.10547","article-title":"Slowing of electroencephalogram in rapid eye movement sleep behavior disorder","volume":"53","author":"Fantini","year":"2003","journal-title":"Ann Neurol."},{"issue":"11","key":"2023120718561470200_CIT0008","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/j.sleep.2013.06.013","article-title":"Electroencephalogram slowing in rapid eye movement sleep behavior disorder is associated with mild cognitive impairment","volume":"14","author":"Rodrigues Braz\u00e8te","year":"2013","journal-title":"Sleep Med."},{"issue":"6","key":"2023120718561470200_CIT0009","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1016\/j.sleep.2010.03.006","article-title":"Electroencephalographic slowing heralds mild cognitive impairment in idiopathic REM sleep behavior disorder","volume":"11","author":"Iranzo","year":"2010","journal-title":"Sleep Med."},{"issue":"12","key":"2023120718561470200_CIT0010","doi-asserted-by":"crossref","first-page":"1893","DOI":"10.5665\/sleep.3224","article-title":"Electroencephalographic findings related with mild cognitive impairment in idiopathic rapid eye movement sleep behavior disorder","volume":"36","author":"Sasai","year":"2013","journal-title":"Sleep."},{"issue":"1","key":"2023120718561470200_CIT0011","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1089\/brain.2011.0069","article-title":"Differential patterns of connectivity in progressive mild cognitive impairment","volume":"2","author":"Bajo","year":"2012","journal-title":"Brain Connect."},{"issue":"1","key":"2023120718561470200_CIT0012","doi-asserted-by":"crossref","first-page":"183","DOI":"10.3233\/JAD-2010-100177","article-title":"Functional connectivity in mild cognitive impairment during a memory task: implications for the disconnection hypothesis","volume":"22","author":"Bajo","year":"2010","journal-title":"J Alzheimers Dis."},{"issue":"12","key":"2023120718561470200_CIT0013","doi-asserted-by":"crossref","first-page":"3936","DOI":"10.1093\/brain\/awz320","article-title":"Hypersynchronization in mild cognitive impairment: the \u2018X\u2019 model","volume":"142","author":"Pusil","year":"2019","journal-title":"Brain."},{"issue":"6","key":"2023120718561470200_CIT0014","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1161\/01.STR.32.6.1318","article-title":"A new rating scale for age-related white matter changes applicable to MRI and CT","volume":"32","author":"Wahlund","year":"2001","journal-title":"Stroke."},{"issue":"2","key":"2023120718561470200_CIT0015","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/s10072-015-2409-5","article-title":"Parkinson\u2019s Disease Sleep Scale 2: application in an Italian population","volume":"37","author":"Arnaldi","year":"2016","journal-title":"Neurol Sci."},{"issue":"1","key":"2023120718561470200_CIT0016","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1002\/mds.22899","article-title":"Cognitive-nigrostriatal relationships in de novo, drug-na\u00efve Parkinson\u2019s disease patients: a [123I]FP-CIT SPECT study","volume":"25","author":"Nobili","year":"2010","journal-title":"Mov Disord."},{"issue":"2","key":"2023120718561470200_CIT0017","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1007\/s00259-009-1267-x","article-title":"EANM procedure guidelines for brain neurotransmission SPECT using 123I-labelled dopamine transporter ligands, version 2","volume":"37","author":"Darcourt","year":"2010","journal-title":"Eur J Nucl Med Mol Imaging."},{"issue":"4","key":"2023120718561470200_CIT0018","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1007\/s00259-012-2304-8","article-title":"Automatic semi-quantification of [123I]FP-CIT SPECT scans in healthy volunteers using BasGan version 2: results from the ENC-DAT database","volume":"40","author":"Nobili","year":"2013","journal-title":"Eur J Nucl Med Mol Imaging."},{"key":"2023120718561470200_CIT0019","doi-asserted-by":"crossref","first-page":"879716","DOI":"10.1155\/2011\/879716","article-title":"Brainstorm: a user-friendly application for MEG\/EEG analysis","volume":"2011","author":"Tadel","year":"2011","journal-title":"Comput Intell Neurosci."},{"issue":"2","key":"2023120718561470200_CIT0020","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/0013-4694(89)90180-6","article-title":"Spherical splines for scalp potential and current density mapping","volume":"72","author":"Perrin","year":"1989","journal-title":"Electroencephalogr Clin Neurophysiol."},{"key":"2023120718561470200_CIT0021","article-title":"Erratum: spherical splines for scalp potential and current density mapping (Electroenceph. Clin. Neurophysiol. 1989, 72:184\u2013187)","author":"Perrin","year":"1990","journal-title":"Electroencephalogr Clin Neurophysiol."},{"issue":"12","key":"2023120718561470200_CIT0022","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1038\/s41593-020-00744-x","article-title":"Parameterizing neural power spectra into periodic and aperiodic components","volume":"23","author":"Donoghue","year":"2020","journal-title":"Nat Neurosci."},{"issue":"1","key":"2023120718561470200_CIT0023","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1175\/1520-0477(1998)079<0061:APGTWA>2.0.CO;2","article-title":"A practical guide to wavelet analysis","volume":"79","author":"Torrence","year":"1998","journal-title":"Bull Am Meteorol Soc."},{"issue":"4","key":"2023120718561470200_CIT0024","doi-asserted-by":"crossref","first-page":"1548","DOI":"10.1016\/j.neuroimage.2011.01.055","article-title":"An improved index of phase-synchronization for electrophysiological data in the presence of volume-conduction, noise and sample-size bias","volume":"55","author":"Vinck","year":"2011","journal-title":"Neuroimage."},{"key":"2023120718561470200_CIT0025","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/j.neuroimage.2018.02.032","article-title":"Ghost interactions in MEG\/EEG source space: a note of caution on inter-areal coupling measures","volume":"173","author":"Palva","year":"2018","journal-title":"Neuroimage."},{"issue":"1","key":"2023120718561470200_CIT0026","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.neuron.2015.09.034","article-title":"Rhythms for cognition: communication through coherence","volume":"88","author":"Fries","year":"2015","journal-title":"Neuron."},{"issue":"6","key":"2023120718561470200_CIT0027","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1038\/nn.3101","article-title":"Large-scale cortical correlation structure of spontaneous oscillatory activity","volume":"15","author":"Hipp","year":"2012","journal-title":"Nat Neurosci."},{"key":"2023120718561470200_CIT0028","author":"Schurger","year":"2011"},{"key":"2023120718561470200_CIT0029","author":"Groppe","year":"2015"},{"key":"2023120718561470200_CIT0030","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1186\/1748-717X-8-293","article-title":"Multiple comparisons permutation test for image based data mining in radiotherapy","volume":"8","author":"Chen","year":"2013","journal-title":"Radiat Oncol."},{"issue":"6","key":"2023120718561470200_CIT0031","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1111\/jsr.12309","article-title":"REM sleep behaviour disorder is associated with lower fast and higher slow sleep spindle densities","volume":"24","author":"O\u2019Reilly","year":"2015","journal-title":"J Sleep Res."},{"key":"2023120718561470200_CIT0032","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.neurobiolaging.2015.10.007","article-title":"Electroencephalogram slowing predicts neurodegeneration in rapid eye movement sleep behavior disorder","volume":"37","author":"Rodrigues Braz\u00e8te","year":"2016","journal-title":"Neurobiol Aging."},{"issue":"4","key":"2023120718561470200_CIT0033","doi-asserted-by":"crossref","first-page":"766","DOI":"10.1016\/j.clinph.2018.01.009","article-title":"Functional cortical source connectivity of resting state electroencephalographic alpha rhythms shows similar abnormalities in patients with mild cognitive impairment due to Alzheimer\u2019s and Parkinson\u2019s diseases","volume":"129","author":"Babiloni","year":"2018","journal-title":"Clin Neurophysiol."},{"key":"2023120718561470200_CIT0034","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.neurobiolaging.2019.01.013","article-title":"Abnormalities of functional cortical source connectivity of resting-state electroencephalographic alpha rhythms are similar in patients with mild cognitive impairment due to Alzheimer\u2019s and Lewy body diseases","volume":"77","author":"Babiloni","year":"2019","journal-title":"Neurobiol Aging."},{"issue":"3","key":"2023120718561470200_CIT0035","first-page":"694","article-title":"Evolution of source EEG synchronization in early Alzheimer \u2019 s disease","volume":"34","author":"Knyazeva","year":"2013","journal-title":"NBA"},{"issue":"44","key":"2023120718561470200_CIT0036","doi-asserted-by":"crossref","first-page":"14551","DOI":"10.1523\/JNEUROSCI.0964-14.2014","article-title":"Alpha-band hypersynchronization in progressive mild cognitive impairment: a magnetoencephalography study","volume":"34","author":"L\u00f3pez","year":"2014","journal-title":"J Neurosci."},{"issue":"4","key":"2023120718561470200_CIT0037","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/BF00308809","article-title":"Neuropathological stageing of Alzheimer-related changes","volume":"82","author":"Braak","year":"1991","journal-title":"Acta Neuropathol."},{"issue":"4","key":"2023120718561470200_CIT0038","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/0896-6273(91)90052-2","article-title":"The molecular pathology of Alzheimer\u2019s disease","volume":"6","author":"Selkoe","year":"1991","journal-title":"Neuron."},{"issue":"6","key":"2023120718561470200_CIT0039","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsx058","article-title":"Altered functional connectivity in idiopathic rapid eye movement sleep behavior disorder: a resting-state EEG study","volume":"40","author":"Sunwoo","year":"2017","journal-title":"Sleep"},{"key":"2023120718561470200_CIT0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.nicl.2019.102138","article-title":"Disruption of posterior brain functional connectivity and its relation to cognitive impairment in idiopathic REM sleep behavior disorder","volume":"25","author":"Campabadal","year":"2020","journal-title":"NeuroImage Clin."},{"issue":"12","key":"2023120718561470200_CIT0041","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.5665\/sleep.3222","article-title":"Altered nigrostriatal and nigrocortical functional connectivity in rapid eye movement sleep behavior disorder","volume":"36","author":"Ellmore","year":"2013","journal-title":"Sleep."},{"key":"2023120718561470200_CIT0042","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.sleep.2020.01.010","article-title":"Altered resting-state thalamo-occipital functional connectivity is associated with cognition in isolated rapid eye movement sleep behavior disorder","volume":"69","author":"Byun","year":"2020","journal-title":"Sleep Med."},{"issue":"Pt 8","key":"2023120718561470200_CIT0043","doi-asserted-by":"crossref","first-page":"2224","DOI":"10.1093\/brain\/aww124","article-title":"Basal ganglia dysfunction in idiopathic REM sleep behaviour disorder parallels that in early Parkinson\u2019s disease","volume":"139","author":"Rolinski","year":"2016","journal-title":"Brain."},{"key":"2023120718561470200_CIT0044","doi-asserted-by":"crossref","first-page":"151","DOI":"10.2147\/NSS.S134864","article-title":"Short- and long-term health consequences of sleep disruption","volume":"9","author":"Medic","year":"2017","journal-title":"Nat Sci Sleep."},{"key":"2023120718561470200_CIT0045","doi-asserted-by":"crossref","first-page":"17","DOI":"10.3389\/neuro.07.017.2009","article-title":"Neural synchrony in cortical networks: history, concept and current status","volume":"3","author":"Uhlhaas","year":"2009","journal-title":"Front Integr Neurosci."},{"issue":"4","key":"2023120718561470200_CIT0046","doi-asserted-by":"crossref","first-page":"e1003548","DOI":"10.1371\/journal.pcbi.1003548","article-title":"Mechanisms of zero-lag synchronization in cortical motifs","volume":"10","author":"Gollo","year":"2014","journal-title":"PLoS Comput Biol."},{"issue":"6612","key":"2023120718561470200_CIT0047","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1038\/385157a0","article-title":"Visuomotor integration is associated with zero time-lag synchronization among cortical areas","volume":"385","author":"Roelfsema","year":"1997","journal-title":"Nature."},{"key":"2023120718561470200_CIT0048","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.neuroimage.2018.12.008","article-title":"Changes in functional connectivity dynamics with aging: a dynamical phase synchronization approach","volume":"188","author":"Nobukawa","year":"2019","journal-title":"Neuroimage."}],"container-title":["SLEEP"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/sleep\/advance-article-pdf\/doi\/10.1093\/sleep\/zsab232\/40502722\/zsab232.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/sleep\/article-pdf\/45\/1\/zsab232\/54092543\/zsab232.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/sleep\/article-pdf\/45\/1\/zsab232\/54092543\/zsab232.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,7]],"date-time":"2023-12-07T17:41:49Z","timestamp":1701970909000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/sleep\/article\/doi\/10.1093\/sleep\/zsab232\/6374127"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,9,22]]},"references-count":48,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2021,9,22]]},"published-print":{"date-parts":[[2022,1,11]]}},"URL":"https:\/\/doi.org\/10.1093\/sleep\/zsab232","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2021.03.12.435081","asserted-by":"object"}]},"ISSN":["0161-8105","1550-9109"],"issn-type":[{"value":"0161-8105","type":"print"},{"value":"1550-9109","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,1,1]]},"published":{"date-parts":[[2021,9,22]]},"article-number":"zsab232"}}