{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T17:13:38Z","timestamp":1770743618935,"version":"3.49.0"},"reference-count":65,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2021,12,27]],"date-time":"2021-12-27T00:00:00Z","timestamp":1640563200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"funder":[{"DOI":"10.13039\/100000097","name":"National Center for Research Resources","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000097","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["1 UL1 RR024150-01"],"award-info":[{"award-number":["1 UL1 RR024150-01"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Mayo Clinic Alzheimer\u2019s Disease Research Center Grant"},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["P50 AG016574"],"award-info":[{"award-number":["P50 AG016574"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"publisher","award":["R34AG056639"],"award-info":[{"award-number":["R34AG056639"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,4,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Study Objectives<\/jats:title>\n                  <jats:p>To analyze cognitive deficits leading to unsafe driving in patients with REM Sleep Behavior Disorder (RBD), strongly associated with cognitive impairment and synucleinopathy-related neurodegeneration.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Twenty isolated RBD (iRBD), 10 symptomatic RBD (sRBD), and 20 age- and education-matched controls participated in a prospective case-control driving simulation study. Group mean differences were compared with correlations between cognitive and driving safety measures.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>iRBD and sRBD patients were more cognitively impaired than controls in global neurocognitive functioning, processing speeds, visuospatial attention, and distractibility (p &amp;lt; .05). sRBD patients drove slower with more collisions than iRBD patients and controls (p &amp;lt; .05), required more warnings, and had greater difficulty following and matching speed of a lead car during simulated car-following tasks (p &amp;lt; .05). Driving safety measures were similar between iRBD patients and controls. Slower psychomotor speed correlated with more off-road accidents (r = 0.65) while processing speed (\u22120.88), executive function (\u22120.90), and visuospatial impairment (0.74) correlated with safety warnings in sRBD patients. Slower stimulus recognition was associated with more signal-light (0.64) and stop-sign (0.56) infractions in iRBD patients.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>iRBD and sRBD patients have greater selective cognitive impairments than controls, particularly visuospatial abilities and processing speed. sRBD patients exhibited unsafe driving behaviors, associated with processing speed, visuospatial awareness, and attentional impairments. Our results suggest that iRBD patients have similar driving-simulator performance as healthy controls but that driving capabilities regress as RBD progresses to symptomatic RBD with overt signs of cognitive, autonomic, and motor impairment. Longitudinal studies with serial driving simulator evaluations and objective on-road driving performance are needed.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/sleep\/zsab253","type":"journal-article","created":{"date-parts":[[2021,12,27]],"date-time":"2021-12-27T20:40:20Z","timestamp":1640637620000},"source":"Crossref","is-referenced-by-count":3,"title":["Cognition and driving ability in isolated and symptomatic REM sleep behavior disorder"],"prefix":"10.1093","volume":"45","author":[{"given":"David J","family":"Sandness","sequence":"first","affiliation":[{"name":"Mayo Sleep Behavior and Neurophysiology Research Laboratory , Rochester, MN , USA"},{"name":"Mayo Center for Sleep Medicine , Rochester, MN , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stuart J","family":"McCarter","sequence":"additional","affiliation":[{"name":"Mayo Sleep Behavior and Neurophysiology Research Laboratory , Rochester, MN , USA"},{"name":"Mayo Center for Sleep Medicine , Rochester, MN , USA"},{"name":"Department of Neurology, Mayo Clinic and Foundation , Rochester, MN , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucas G","family":"Dueffert","sequence":"additional","affiliation":[{"name":"Mayo Sleep Behavior and Neurophysiology Research Laboratory , Rochester, MN , USA"},{"name":"Park Nicollet Rehabilitation , Maple Grove, MN , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul W","family":"Shepard","sequence":"additional","affiliation":[{"name":"Mayo Sleep Behavior and Neurophysiology Research Laboratory , Rochester, MN , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashley M","family":"Enke","sequence":"additional","affiliation":[{"name":"Mayo Sleep Behavior and Neurophysiology Research Laboratory , Rochester, MN , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Julie","family":"Fields","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Mayo Clinic and Foundation , Rochester, MN , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michelle M","family":"Mielke","sequence":"additional","affiliation":[{"name":"Department of Neurology, Mayo Clinic and Foundation , Rochester, MN , USA"},{"name":"Department of Health Sciences Research, Mayo Clinic and Foundation , Rochester, MN , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4153-8187","authenticated-orcid":false,"given":"Bradley F","family":"Boeve","sequence":"additional","affiliation":[{"name":"Mayo Center for Sleep Medicine , Rochester, MN , USA"},{"name":"Department of Neurology, Mayo Clinic and Foundation , Rochester, MN , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael H","family":"Silber","sequence":"additional","affiliation":[{"name":"Mayo Center for Sleep Medicine , Rochester, MN , USA"},{"name":"Department of Neurology, Mayo Clinic and Foundation , Rochester, MN , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2833-8826","authenticated-orcid":false,"given":"Erik K","family":"St. Louis","sequence":"additional","affiliation":[{"name":"Mayo Sleep Behavior and Neurophysiology Research Laboratory , Rochester, MN , USA"},{"name":"Mayo Center for Sleep Medicine , Rochester, MN , USA"},{"name":"Department of Neurology, Mayo Clinic and Foundation , Rochester, MN , USA"},{"name":"Department of Medicine, Mayo Clinic and Foundation , Rochester, MN , USA"},{"name":"Mayo Clinic Health System Southwest Wisconsin , La Crosse, WI , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2021,12,27]]},"reference":[{"issue":"8","key":"2022080801003113300_CIT0001","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.5665\/sleep.2874","article-title":"REM sleep behavior disorder in the Korean elderly population: prevalence and clinical characteristics","volume":"36","author":"Kang","year":"2013","journal-title":"Sleep."},{"issue":"2","key":"2022080801003113300_CIT0002","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsx197","article-title":"Prevalence and determinants of rapid eye movement sleep behavior disorder in the general population","volume":"41","author":"Haba-Rubio","year":"2018","journal-title":"Sleep."},{"issue":"1","key":"2022080801003113300_CIT0003","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1002\/ana.22655","article-title":"Probable rapid eye movement sleep behavior disorder increases risk for mild cognitive impairment and Parkinson disease: a population-based study","volume":"71","author":"Boot","year":"2012","journal-title":"Ann Neurol."},{"key":"2022080801003113300_CIT0004","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1111\/j.1749-6632.2009.05115.x","article-title":"REM sleep behavior disorder: updated review of the core features, the REM sleep behavior disorder-neurodegenerative disease association, evolving concepts, controversies, and future directions","volume":"1184","author":"Boeve","year":"2010","journal-title":"Ann N Y Acad Sci."},{"issue":"1","key":"2022080801003113300_CIT0005","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1212\/01.WNL.0000073619.94467.B0","article-title":"Synucleinopathy pathology and REM sleep behavior disorder plus dementia or parkinsonism","volume":"61","author":"Boeve","year":"2003","journal-title":"Neurology."},{"issue":"Pt 11","key":"2022080801003113300_CIT0006","doi-asserted-by":"crossref","first-page":"2770","DOI":"10.1093\/brain\/awm056","article-title":"Pathophysiology of REM sleep behaviour disorder and relevance to neurodegenerative disease","volume":"130","author":"Boeve","year":"2007","journal-title":"Brain."},{"issue":"3","key":"2022080801003113300_CIT0007","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1093\/brain\/awz030","article-title":"Risk and predictors of dementia and Parkinsonism in idiopathic REM sleep behaviour disorder: a multicentre study","volume":"142","author":"Postuma","year":"2019","journal-title":"Brain."},{"issue":"15","key":"2022080801003113300_CIT0008","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1212\/01.wnl.0000286943.79593.a6","article-title":"Executive dysfunction and memory impairment in idiopathic REM sleep behavior disorder","volume":"70","author":"Massicotte-Marquez","year":"2008","journal-title":"Neurology."},{"issue":"19","key":"2022080801003113300_CIT0009","doi-asserted-by":"crossref","first-page":"1843","DOI":"10.1212\/01.wnl.0000278114.14096.74","article-title":"REM sleep behavior disorder predicts cognitive impairment in Parkinson disease without dementia","volume":"69","author":"Vendette","year":"2007","journal-title":"Neurology."},{"issue":"5","key":"2022080801003113300_CIT0010","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1002\/ana.25239","article-title":"How does dementia with Lewy bodies start? prodromal cognitive changes in REM sleep behavior disorder","volume":"83","author":"G\u00e9nier Marchand","year":"2018","journal-title":"Ann Neurol."},{"issue":"3","key":"2022080801003113300_CIT0011","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1097\/00002093-199809000-00003","article-title":"Factors associated with motor vehicle crashes in cognitively impaired older adults","volume":"12","author":"B\u00e9dard","year":"1998","journal-title":"Alzheimer Dis Assoc Disord."},{"issue":"3","key":"2022080801003113300_CIT0012","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1093\/geronb\/gbq003","article-title":"Changes in mobility among older adults with psychometrically defined mild cognitive impairment","volume":"65B","author":"O\u2019Connor","year":"2010","journal-title":"J Gerontol B Psychol Sci Soc Sci."},{"issue":"1","key":"2022080801003113300_CIT0013","doi-asserted-by":"crossref","first-page":"77","DOI":"10.2217\/ahe.09.83","article-title":"How does dementia affect driving in older patients?","volume":"6","author":"Ott","year":"2010","journal-title":"Aging Health."},{"issue":"10","key":"2022080801003113300_CIT0014","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1001\/jama.2011.252","article-title":"Impaired driving from medical conditions: a 70-year-old man trying to decide if he should continue driving","volume":"305","author":"Rizzo","year":"2011","journal-title":"JAMA."},{"issue":"11","key":"2022080801003113300_CIT0015","first-page":"3110","article-title":"Visual attention problems as a predictor of vehicle crashes in older drivers","volume":"34","author":"Ball","year":"1993","journal-title":"Invest Ophthalmol Vis Sci."},{"issue":"3","key":"2022080801003113300_CIT0016","first-page":"357","article-title":"Preliminary report of the hepatic encephalopathy assessment driving simulator (HEADS) score","volume":"18","author":"Baskin-Bey","year":"2008","journal-title":"Ethn Dis."},{"issue":"7","key":"2022080801003113300_CIT0017","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1017\/S1355617799577011","article-title":"The impact of HIV-related neuropsychological dysfunction on driving behavior. The HNRC Group","volume":"5","author":"Marcotte","year":"1999","journal-title":"J Int Neuropsychol Soc."},{"issue":"1","key":"2022080801003113300_CIT0018","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1097\/00002093-200101000-00002","article-title":"Simulated car crashes at intersections in drivers with Alzheimer disease","volume":"15","author":"Rizzo","year":"2001","journal-title":"Alzheimer Dis Assoc Disord."},{"issue":"5","key":"2022080801003113300_CIT0019","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1001\/archneur.1997.00550170027011","article-title":"Simulated car crashes and crash predictors in drivers with Alzheimer disease","volume":"54","author":"Rizzo","year":"1997","journal-title":"Arch Neurol."},{"issue":"1","key":"2022080801003113300_CIT0020","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/j.1532-5415.2011.03739.x","article-title":"Cognitive functioning predicts driver safety on road tests 1 and 2 years later","volume":"60","author":"Aksan","year":"2012","journal-title":"J Am Geriatr Soc"},{"key":"2022080801003113300_CIT0021","volume-title":"The International Classification of Sleep Disorders","author":"Medicine AAoS.","year":"2005","edition":"2"},{"key":"2022080801003113300_CIT0022","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1001\/archpsyc.1965.01720310065008","article-title":"A Self-Rating Depression Scale","volume":"12","author":"ZUNG","year":"1965","journal-title":"Arch Gen Psychiatry."},{"issue":"2","key":"2022080801003113300_CIT0023","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0165-1781(89)90047-4","article-title":"The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research","volume":"28","author":"Buysse","year":"1989","journal-title":"Psychiatry Res."},{"issue":"6","key":"2022080801003113300_CIT0024","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1093\/sleep\/14.6.540","article-title":"A new method for measuring daytime sleepiness: the Epworth sleepiness scale","volume":"14","author":"Johns","year":"1991","journal-title":"Sleep."},{"issue":"4","key":"2022080801003113300_CIT0025","doi-asserted-by":"crossref","first-page":"M203","DOI":"10.1093\/gerona\/54.4.M203","article-title":"Older drivers and cataract: driving habits and crash risk","volume":"54","author":"Owsley","year":"1999","journal-title":"J Gerontol A Biol Sci Med Sci."},{"issue":"3","key":"2022080801003113300_CIT0026","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1136\/jnnp.55.3.181","article-title":"Accuracy of clinical diagnosis of idiopathic Parkinson\u2019s disease: a clinico-pathological study of 100 cases","volume":"55","author":"Hughes","year":"1992","journal-title":"J Neurol Neurosurg Psychiatry."},{"issue":"4","key":"2022080801003113300_CIT0027","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0025-6196(12)61905-3","article-title":"A short test of mental status: description and preliminary results","volume":"62","author":"Kokmen","year":"1987","journal-title":"Mayo Clin Proc."},{"issue":"8","key":"2022080801003113300_CIT0028","doi-asserted-by":"crossref","first-page":"1516","DOI":"10.1016\/j.mayocp.2019.01.043","article-title":"Comparison of the short test of mental status and the Montreal cognitive assessment across the cognitive spectrum","volume":"94","author":"Townley","year":"2019","journal-title":"Mayo Clin Proc."},{"issue":"9","key":"2022080801003113300_CIT0029","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1212\/01.wnl.0000324625.00404.15","article-title":"Second consensus statement on the diagnosis of multiple system atrophy","volume":"71","author":"Gilman","year":"2008","journal-title":"Neurology."},{"key":"2022080801003113300_CIT0030","doi-asserted-by":"crossref","first-page":"417","DOI":"10.3233\/JAD-2006-9S347","article-title":"Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the Consortium on DLB International Workshop","volume":"9","author":"McKeith","year":"2006","journal-title":"J Alzheimers Dis."},{"issue":"9","key":"2022080801003113300_CIT0031","doi-asserted-by":"crossref","first-page":"1133","DOI":"10.1212\/WNL.56.9.1133","article-title":"Practice parameter: early detection of dementia: mild cognitive impairment (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology","volume":"56","author":"Petersen","year":"2001","journal-title":"Neurology."},{"issue":"7","key":"2022080801003113300_CIT0032","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.acn.2006.05.007","article-title":"Reliability and validity of a computerized neurocognitive test battery, CNS Vital Signs","volume":"21","author":"Gualtieri","year":"2006","journal-title":"Arch Clin Neuropsychol."},{"issue":"1","key":"2022080801003113300_CIT0033","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1080\/09084282.2012.721149","article-title":"Minimal gender differences on the CNS vital signs computerized neurocognitive battery","volume":"21","author":"Iverson","year":"2014","journal-title":"Appl Neuropsychol Adult."},{"issue":"8","key":"2022080801003113300_CIT0034","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1177\/0883073811430863","article-title":"Computerized neuropsychological testing to rapidly evaluate cognition in pediatric patients with neurologic disorders","volume":"27","author":"Brooks","year":"2012","journal-title":"J Child Neurol."},{"issue":"4","key":"2022080801003113300_CIT0035","first-page":"90","article-title":"A computerized test battery sensitive to mild and severe brain injury","volume":"10","author":"Gualtieri","year":"2008","journal-title":"Medscape J Med."},{"issue":"3","key":"2022080801003113300_CIT0036","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1080\/09084280903098778","article-title":"Rapid computerized assessment of neurocognitive deficits in bipolar disorder","volume":"16","author":"Iverson","year":"2009","journal-title":"Appl Neuropsychol."},{"issue":"4","key":"2022080801003113300_CIT0037","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1080\/09084280903297594","article-title":"Identifying neurocognitive impairment in depression using computerized testing","volume":"16","author":"Iverson","year":"2009","journal-title":"Appl Neuropsychol."},{"issue":"5","key":"2022080801003113300_CIT0038","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1097\/JSM.0b013e318295a834","article-title":"The effects of sleep quality and sleep quantity on concussion baseline assessment","volume":"23","author":"Mihalik","year":"2013","journal-title":"Clin J Sport Med."},{"key":"2022080801003113300_CIT0039","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.aap.2014.03.011","article-title":"Cognitive and visual predictors of UFOV performance in older adults","volume":"70","author":"Matas","year":"2014","journal-title":"Accid Anal Prev."},{"issue":"3","key":"2022080801003113300_CIT0040","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1037\/0882-7974.6.3.403","article-title":"Visual\/cognitive correlates of vehicle accidents in older drivers","volume":"6","author":"Owsley","year":"1991","journal-title":"Psychol Aging."},{"issue":"14","key":"2022080801003113300_CIT0041","doi-asserted-by":"crossref","first-page":"1083","DOI":"10.1001\/jama.279.14.1083","article-title":"Visual processing impairment and risk of motor vehicle crash among older adults","volume":"279","author":"Owsley","year":"1998","journal-title":"JAMA."},{"issue":"6","key":"2022080801003113300_CIT0042","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/S0001-4575(01)00089-6","article-title":"Effects of an afternoon nap on nighttime alertness and performance in long-haul drivers","volume":"34","author":"Macchi","year":"2002","journal-title":"Accid Anal Prev."},{"issue":"1","key":"2022080801003113300_CIT0043","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1097\/00001199-200202000-00005","article-title":"Divided attention and driving: a pilot study using virtual reality technology","volume":"17","author":"Lengenfelder","year":"2002","journal-title":"J Head Trauma Rehabil."},{"issue":"3","key":"2022080801003113300_CIT0044","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1016\/j.aap.2009.04.023","article-title":"Age-related declines in car following performance under simulated fog conditions","volume":"42","author":"Ni","year":"2010","journal-title":"Accid Anal Prev."},{"issue":"5","key":"2022080801003113300_CIT0045","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1007\/s11910-008-0059-1","article-title":"Driving and neurodegenerative diseases","volume":"8","author":"Uc","year":"2008","journal-title":"Curr Neurol Neurosci Rep."},{"issue":"4","key":"2022080801003113300_CIT0046","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1002\/ana.20958","article-title":"Impaired visual search in drivers with Parkinson\u2019s disease","volume":"60","author":"Uc","year":"2006","journal-title":"Ann Neurol."},{"issue":"Pt 9","key":"2022080801003113300_CIT0047","doi-asserted-by":"crossref","first-page":"2433","DOI":"10.1093\/brain\/awm178","article-title":"Impaired navigation in drivers with Parkinson\u2019s disease","volume":"130","author":"Uc","year":"2007","journal-title":"Brain."},{"issue":"3","key":"2022080801003113300_CIT0048","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1037\/neu0000006","article-title":"Impaired visual perception in rapid eye movement sleep behavior disorder","volume":"28","author":"Plomhause","year":"2014","journal-title":"Neuropsychology."},{"issue":"4","key":"2022080801003113300_CIT0049","doi-asserted-by":"crossref","first-page":"841","DOI":"10.1177\/0018720812465769","article-title":"Naturalistic distraction and driving safety in older drivers","volume":"55","author":"Aksan","year":"2013","journal-title":"Hum Factors."},{"issue":"3","key":"2022080801003113300_CIT0050","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1136\/jnnp.64.3.325","article-title":"Decreased driving ability in people with Parkinson\u2019s disease","volume":"64","author":"Heikkil\u00e4","year":"1998","journal-title":"J Neurol Neurosurg Psychiatry."},{"issue":"4","key":"2022080801003113300_CIT0051","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1097\/OPX.0b013e31824c17ee","article-title":"Useful field of view predicts driving in the presence of distracters","volume":"89","author":"Wood","year":"2012","journal-title":"Optom Vis Sci."},{"issue":"14","key":"2022080801003113300_CIT0052","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1212\/01.wnl.0000277640.58685.fc","article-title":"Predictors of fitness to drive in people with Parkinson disease","volume":"69","author":"Devos","year":"2007","journal-title":"Neurology."},{"issue":"7","key":"2022080801003113300_CIT0053","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1002\/mds.20420","article-title":"Impact of internal versus external cueing on driving performance in people with Parkinson\u2019s disease","volume":"20","author":"Stolwyk","year":"2005","journal-title":"Mov Disord."},{"issue":"12","key":"2022080801003113300_CIT0054","doi-asserted-by":"crossref","first-page":"2096","DOI":"10.1002\/mds.21115","article-title":"Effect of a concurrent task on driving performance in people with Parkinson\u2019s disease","volume":"21","author":"Stolwyk","year":"2006","journal-title":"Mov Disord."},{"issue":"10","key":"2022080801003113300_CIT0055","doi-asserted-by":"crossref","DOI":"10.1093\/sleep\/zsx134","article-title":"Risk of motor vehicle accidents related to sleepiness at the wheel: a systematic review and meta-analysis","volume":"40","author":"Bioulac","year":"2017","journal-title":"Sleep."},{"issue":"4","key":"2022080801003113300_CIT0056","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.jsmc.2019.08.001","article-title":"Sleep apnea, sleepiness, and driving risk","volume":"14","author":"Bonsignore","year":"2019","journal-title":"Sleep Med Clin."},{"issue":"4","key":"2022080801003113300_CIT0057","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.jsmc.2019.07.002","article-title":"Sleep restriction, sleep hygiene, and driving safety: the importance of situational sleepiness","volume":"14","author":"Philip","year":"2019","journal-title":"Sleep Med Clin."},{"issue":"5","key":"2022080801003113300_CIT0058","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/j.cjtee.2017.03.005","article-title":"A systematic review of the effect of various interventions on reducing fatigue and sleepiness while driving","volume":"20","author":"Nazari","year":"2017","journal-title":"Chin J Traumatol."},{"key":"2022080801003113300_CIT0059","doi-asserted-by":"crossref","first-page":"2376","DOI":"10.12688\/f1000research.9608.2","article-title":"Creating a driving profile for older adults using GPS devices and naturalistic driving methodology","volume":"5","author":"Babulal","year":"2016","journal-title":"F1000Res."},{"issue":"16","key":"2022080801003113300_CIT0060","doi-asserted-by":"crossref","first-page":"1316","DOI":"10.1212\/WNL.0b013e3181da3b0f","article-title":"Practice parameter update: evaluation and management of driving risk in dementia: report of the Quality Standards Subcommittee of the American Academy of Neurology","volume":"74","author":"Iverson","year":"2010","journal-title":"Neurology."},{"issue":"5","key":"2022080801003113300_CIT0061","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1378\/chest.90.5.686","article-title":"Cognitive impairment in patients with obstructive sleep apnea and associated hypoxemia","volume":"90","author":"Findley","year":"1986","journal-title":"Chest."},{"issue":"3","key":"2022080801003113300_CIT0062","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1007\/s11325-017-1563-9","article-title":"Prevalence of obstructive sleep apnea in REM behaviour disorder: response to continuous positive airway pressure therapy","volume":"22","author":"Gabryelska","year":"2018","journal-title":"Sleep Breath."},{"issue":"1","key":"2022080801003113300_CIT0063","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.sleep.2007.11.019","article-title":"Idiopathic rapid-eye-movement sleep disorder: associations with antidepressants, psychiatric diagnoses, and other factors, in relation to age of onset","volume":"10","author":"Teman","year":"2009","journal-title":"Sleep Med."},{"issue":"3","key":"2022080801003113300_CIT0064","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.sleep.2012.09.018","article-title":"Treatment outcomes in REM sleep behavior disorder","volume":"14","author":"McCarter","year":"2013","journal-title":"Sleep Med."},{"issue":"3","key":"2022080801003113300_CIT0065","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.sleep.2010.07.022","article-title":"Changing demographics in REM sleep behavior disorder: possible effect of autoimmunity and antidepressants","volume":"12","author":"Ju","year":"2011","journal-title":"Sleep Med."}],"container-title":["Sleep"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/sleep\/advance-article-pdf\/doi\/10.1093\/sleep\/zsab253\/41959550\/zsab253.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/sleep\/article-pdf\/45\/4\/zsab253\/45286961\/zsab253.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/sleep\/article-pdf\/45\/4\/zsab253\/45286961\/zsab253.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,8]],"date-time":"2022-08-08T01:01:11Z","timestamp":1659920471000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/sleep\/article\/doi\/10.1093\/sleep\/zsab253\/6484911"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,27]]},"references-count":65,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,12,27]]},"published-print":{"date-parts":[[2022,4,11]]}},"URL":"https:\/\/doi.org\/10.1093\/sleep\/zsab253","relation":{},"ISSN":["0161-8105","1550-9109"],"issn-type":[{"value":"0161-8105","type":"print"},{"value":"1550-9109","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2022,4,1]]},"published":{"date-parts":[[2021,12,27]]},"article-number":"zsab253"}}