{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T06:49:58Z","timestamp":1778654998283,"version":"3.51.4"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2022,1,11]],"date-time":"2022-01-11T00:00:00Z","timestamp":1641859200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,4,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Restless sleep disorder (RSD) is a newly defined sleep-related movement disorder characterized by large muscle movements (LMM) in sleep. We examined the sleep study, clinical characteristics, and daytime functioning in children with RSD and compared them to children with periodic limb movement disorder (PLMD) or restless legs syndrome (RLS). Video polysomnography from 47 children with restless sleep was retrospectively reviewed for LMM and age- and sex-matched to 34 children with PLMD and 12 children with RLS. Data examined included PSG characteristics, ferritin, Pediatric Quality of Life (PedsQL), and Epworth Sleepiness Scale (ESS). Fourteen children met the clinical criteria for RSD with an LMM index of 5 or more per hour of sleep. Mean ESS was elevated in patients with RSD compared to either the PLMD or RLS groups though the result did not reach statistical significance (RSD = 10.20 \u00b1 6.81, PLMD = 6.19 \u00b1 4.14, RLS = 6.25 \u00b1 4.90). The PedsQL score was significantly decreased in the RLS group compared to RSD and was reduced overall in all three groups (PedsQL Total RSD = 70.76 \u00b1 18.05, PLMD = 57.05 \u00b1 20.33, RLS = 53.24 \u00b1 16.97). Serum ferritin values were similar in all three groups (RSD = 26.89 \u00b1 10.29, PLMD = 33.91 \u00b1 20.31, RLS = 23.69 \u00b1 12.94 ng\/mL, p = ns). Children with RSD demonstrate increased daytime sleepiness compared to PLMD or RLS and all three disease groups showed decreased quality of life. Further studies are needed to examine long-term consequences of RSD.<\/jats:p>","DOI":"10.1093\/sleep\/zsac005","type":"journal-article","created":{"date-parts":[[2022,1,13]],"date-time":"2022-01-13T01:20:46Z","timestamp":1642036846000},"source":"Crossref","is-referenced-by-count":18,"title":["Large body movements on video polysomnography are associated with daytime dysfunction in children with restless sleep disorder"],"prefix":"10.1093","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6284-1898","authenticated-orcid":false,"given":"Wei K","family":"Liu","sequence":"first","affiliation":[{"name":"Division of Neurology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, OH, USA"},{"name":"Division of Pulmonary and Sleep Medicine, Cincinnati Children\u2019s Hospital, Cincinnati, OH, USA"},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas J","family":"Dye","sequence":"additional","affiliation":[{"name":"Division of Neurology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, OH, USA"},{"name":"Division of Pulmonary and Sleep Medicine, Cincinnati Children\u2019s Hospital, Cincinnati, OH, USA"},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Horn","sequence":"additional","affiliation":[{"name":"Division of Neurology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Connor","family":"Patterson","sequence":"additional","affiliation":[{"name":"University of Michigan, Ann Arbor, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Garner","sequence":"additional","affiliation":[{"name":"Division of Neurology, Cincinnati Children\u2019s Hospital Medical Center, Cincinnati, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Narong","family":"Simakajornboon","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Sleep Medicine, Cincinnati Children\u2019s Hospital, Cincinnati, OH, USA"},{"name":"Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2022,1,11]]},"reference":[{"issue":"6","key":"2022041107575276500_CIT0001","doi-asserted-by":"crossref","first-page":"777","DOI":"10.5664\/jcsm.6614","article-title":"Sleep complaints and sleep architecture in children with idiopathic central sleep apnea","volume":"13","author":"Gurbani","year":"2017","journal-title":"J Clin Sleep Med."},{"key":"2022041107575276500_CIT0002","doi-asserted-by":"crossref","first-page":"101406","DOI":"10.1016\/j.smrv.2020.101406","article-title":"Restless sleep in children: a 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