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Logistic regression was used to examine associations between ORPwake, ORPNREM, and traditional polysomnography measures (as comparators) with excessive sleepiness (Epworth sleepiness scale &amp;gt;10) and poor sleep quality (Pittsburgh sleep quality index &amp;gt;5) and insomnia symptoms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>High ORPwake was associated with a ~30% increase in poor sleep quality in both HypnoLaus (odds ratio, OR, and 95% CI) 1.28 (1.09, 1.51), and MAILES 1.36 (1.10, 1.68). High ORPwake was also associated with a ~28% decrease in excessive daytime sleepiness in the MAILES dataset. ORPNREM was associated with a ~30% increase in poor sleep quality in HypnoLaus but not in MAILES. No consistent associations across cohorts were detected using traditional polysomnography markers.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>ORP, a novel EEG-derived metric, measured during wake periods predicts poor sleep quality in two independent cohorts. Consistent with insomnia symptomatology of poor perceived sleep in the absence of excessive daytime sleepiness, ORPwake may provide valuable objective mechanistic insight into physiological hyperarousal.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/sleep\/zsac051","type":"journal-article","created":{"date-parts":[[2022,3,4]],"date-time":"2022-03-04T07:49:50Z","timestamp":1646380190000},"source":"Crossref","is-referenced-by-count":39,"title":["A novel EEG marker predicts perceived sleepiness and poor sleep quality"],"prefix":"10.1093","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0760-0714","authenticated-orcid":false,"given":"Bastien","family":"Lechat","sequence":"first","affiliation":[{"name":"College of Science and Engineering, Flinders University, Adelaide, SA, Australia"},{"name":"Flinders Health and Medical Research Institute Sleep Health\/Adelaide Institute for Sleep Health, Flinders University, College of Medicine and Public Health Adelaide, SA, 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