{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T18:13:22Z","timestamp":1773080002294,"version":"3.50.1"},"reference-count":56,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2023,4,15]],"date-time":"2023-04-15T00:00:00Z","timestamp":1681516800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/501100003669","name":"Korean Centers for Disease Control and Prevention","doi-asserted-by":"crossref","award":["2011-E71004-00"],"award-info":[{"award-number":["2011-E71004-00"]}],"id":[{"id":"10.13039\/501100003669","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003669","name":"Korean Centers for Disease Control and Prevention","doi-asserted-by":"crossref","award":["2012-E71005-00"],"award-info":[{"award-number":["2012-E71005-00"]}],"id":[{"id":"10.13039\/501100003669","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003669","name":"Korean Centers for Disease Control and Prevention","doi-asserted-by":"crossref","award":["2013-E71005-00"],"award-info":[{"award-number":["2013-E71005-00"]}],"id":[{"id":"10.13039\/501100003669","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003669","name":"Korean Centers for Disease Control and Prevention","doi-asserted-by":"crossref","award":["2014-E71003-00"],"award-info":[{"award-number":["2014-E71003-00"]}],"id":[{"id":"10.13039\/501100003669","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003669","name":"Korean Centers for Disease Control and Prevention","doi-asserted-by":"crossref","award":["2015-P71001-00"],"award-info":[{"award-number":["2015-P71001-00"]}],"id":[{"id":"10.13039\/501100003669","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003669","name":"Korean Centers for Disease Control and Prevention","doi-asserted-by":"crossref","award":["2016-E71003-00"],"award-info":[{"award-number":["2016-E71003-00"]}],"id":[{"id":"10.13039\/501100003669","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003669","name":"Korean Centers for Disease Control and Prevention","doi-asserted-by":"crossref","award":["2017-E71001-00"],"award-info":[{"award-number":["2017-E71001-00"]}],"id":[{"id":"10.13039\/501100003669","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100003669","name":"Korean Centers for Disease Control and Prevention","doi-asserted-by":"crossref","award":["2018-E7101-00"],"award-info":[{"award-number":["2018-E7101-00"]}],"id":[{"id":"10.13039\/501100003669","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Korean Ministry of Health & Welfare","award":["HI19C1065"],"award-info":[{"award-number":["HI19C1065"]}]},{"name":"Korean Ministry of Health & Welfare","award":["HI20C0469"],"award-info":[{"award-number":["HI20C0469"]}]},{"DOI":"10.13039\/501100003710","name":"Korea Health Industry Development Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003710","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Korea University Ansan Hospital","award":["O2207181"],"award-info":[{"award-number":["O2207181"]}]},{"name":"Korea University Ansan Hospital","award":["O2206301"],"award-info":[{"award-number":["O2206301"]}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF-2019M3C1B8090803"],"award-info":[{"award-number":["NRF-2019M3C1B8090803"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2020R1A2C2013216"],"award-info":[{"award-number":["2020R1A2C2013216"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF-2020R1I1A1A01071011"],"award-info":[{"award-number":["NRF-2020R1I1A1A01071011"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF-2022R1I1A1A01065700"],"award-info":[{"award-number":["NRF-2022R1I1A1A01065700"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["NRF-2020R1I1A1A01073927"],"award-info":[{"award-number":["NRF-2020R1I1A1A01073927"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Ministry of Education & Future Planning"},{"name":"Ministry of Science, ICT","award":["RS-2022-00155966"],"award-info":[{"award-number":["RS-2022-00155966"]}]},{"name":"Institute of Information & communications Technology Planning & Evaluation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,6,13]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Study Objectives<\/jats:title>\n                  <jats:p>Evidence suggests that sleep\u2013wake cycle disruption could be an early manifestation of neurodegeneration and might even be a risk factor for developing diseases in healthy adults. We investigated the impact of circadian phase change on structural and functional brain deterioration in a late-adulthood population.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We analyzed the data of 1874 participants (mean age 58.6 \u00b1 6.3 years, 50.3% female) from the Korean Genome and Epidemiology Study, who were identified as cognitively unimpaired. The mid-sleep time on free days corrected for sleep debt on workdays (MSFsc) at baseline was adopted as an indicator of the chronotype and used to categorize the participants into three groups. The relationships between the chronotype and longitudinal changes in the gray matter volume (GMV) and cognitive function were investigated (mean interval: 4.2 \u00b1 0.5 years).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>The mean MSFsc of the participants was 2:45 am. The earlier MSFsc was linearly associated with smaller right entorhinal GMV (\u03b2 [SE] = 0.02 [0.01]; p = .001) and lower visual memory function test scores at baseline. Longitudinally, the earlier MSFsc at baseline was only significantly associated with more rapid atrophy in the temporal lobe (\u03b2 [SE] = 0.18 [0.07]; p = .018) and not with other brain lobes or subregions. Moreover, the earlier MSFsc was associated with more deteriorated verbal learning and visual memory function test scores.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>An earlier chronotype in midlife, measured using a questionnaire, can be a valuable indicator for individuals who should be closely monitored for the development of neurodegenerative disorders.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/sleep\/zsad108","type":"journal-article","created":{"date-parts":[[2023,4,16]],"date-time":"2023-04-16T06:59:16Z","timestamp":1681628356000},"source":"Crossref","is-referenced-by-count":13,"title":["Earlier chronotype in midlife as a predictor of accelerated brain aging: a population-based longitudinal cohort study"],"prefix":"10.1093","volume":"46","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1401-9258","authenticated-orcid":false,"given":"Hyeon Jin","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Neurology, Korea University Ansan Hospital , Ansan, Gyeonggi , Republic of Korea"},{"name":"Departments of Neurology and Medical Science, Ewha Womans University School of Medicine and Ewha Medical Research Institute , Seoul , Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Regina E Y","family":"Kim","sequence":"additional","affiliation":[{"name":"Institute of Human Genomic Study, College of Medicine, Korea University, Ansan Hospital , Ansan , Gyeonggi , Republic of Korea"},{"name":"Department of Psychiatry, University of Iowa , Iowa City, Iowa , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6161-1636","authenticated-orcid":false,"given":"Soriul","family":"Kim","sequence":"additional","affiliation":[{"name":"Institute of Human Genomic Study, College of Medicine, Korea University, Ansan Hospital , Ansan , Gyeonggi , Republic of Korea"},{"name":"Division of Sleep Medicine, Department of Medicine, University of Pennsylvania , Philadelphia, Pennsylvania , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung Ku","family":"Lee","sequence":"additional","affiliation":[{"name":"Institute of Human Genomic Study, College of Medicine, Korea University, Ansan Hospital , Ansan , Gyeonggi , Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyang Woon","family":"Lee","sequence":"additional","affiliation":[{"name":"Departments of Neurology and Medical Science, Ewha Womans University School of Medicine and Ewha Medical Research Institute , Seoul , Republic of Korea"},{"name":"Computational Medicine, Graduate Programs in System Health Science & Engineering and Artificial Intelligence Convergence, Ewha Womans University , Seoul , Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chol","family":"Shin","sequence":"additional","affiliation":[{"name":"Institute of Human Genomic Study, College of Medicine, Korea University, Ansan Hospital , Ansan , Gyeonggi , Republic of Korea"},{"name":"Biomedical Research Center, Korea University Ansan Hospital , Ansan , Gyeonggi , Republic of Korea"},{"name":"College of Medicine, Korea University , Seoul , Republic of Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,4,15]]},"reference":[{"issue":"8","key":"2023061309270201100_CIT0001","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1002\/alz.12304","article-title":"Deepen into sleep and wake patterns across Alzheimer\u2019s disease phenotypes","volume":"17","author":"Falg\u00e0s","year":"2021","journal-title":"Alzheimers Dementia"},{"issue":"1","key":"2023061309270201100_CIT0002","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.jsmc.2017.09.006","article-title":"Neurodegenerative disorders and sleep","volume":"13","author":"Malhotra","year":"2018","journal-title":"Sleep Med Clin"},{"issue":"4","key":"2023061309270201100_CIT0003","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.3233\/JAD-160385","article-title":"Sleep-wake profile in dementia with Lewy bodies, Alzheimer\u2019s disease, and normal aging","volume":"55","author":"Cagnin","year":"2017","journal-title":"J Alzheimers Dis."},{"issue":"10","key":"2023061309270201100_CIT0004","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1001\/jamaneurol.2021.2876","article-title":"Association of short and long sleep duration with amyloid-\u03b2 burden and cognition in aging","volume":"78","author":"Winer","year":"2021","journal-title":"JAMA Neurol"},{"issue":"1","key":"2023061309270201100_CIT0005","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41467-021-22354-2","article-title":"Association of sleep duration in middle and old age with incidence of dementia","volume":"12","author":"Sabia","year":"2021","journal-title":"Nat Commun."},{"key":"2023061309270201100_CIT0006","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.sleep.2015.08.021","article-title":"Self-reported sleep duration and cognitive performance in older adults: a systematic review and meta-analysis","volume":"17","author":"Lo","year":"2016","journal-title":"Sleep Med."},{"key":"2023061309270201100_CIT0007","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.nlm.2017.04.011","article-title":"Sleep quality and duration in relation to memory in the elderly: initial results from the hellenic longitudinal investigation of aging and diet","volume":"141","author":"Tsapanou","year":"2017","journal-title":"Neurobiol Learn Mem."},{"issue":"7","key":"2023061309270201100_CIT0008","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1038\/nn.4035","article-title":"\u03b2-amyloid disrupts human NREM slow waves and related hippocampus-dependent memory consolidation","volume":"18","author":"Mander","year":"2015","journal-title":"Nat Neurosci."},{"issue":"3","key":"2023061309270201100_CIT0009","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/nn.3324","article-title":"Prefrontal atrophy, disrupted NREM slow waves and impaired hippocampal-dependent memory in aging","volume":"16","author":"Mander","year":"2013","journal-title":"Nat Neurosci."},{"issue":"1","key":"2023061309270201100_CIT0010","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jsmc.2017.09.001","article-title":"Sleep in normal aging","volume":"13","author":"Li","year":"2018","journal-title":"Sleep Med Clin"},{"issue":"4","key":"2023061309270201100_CIT0011","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.sleep.2013.11.791","article-title":"Effects of aging on sleep structure throughout adulthood: a population-based study","volume":"15","author":"Moraes","year":"2014","journal-title":"Sleep Med."},{"issue":"6","key":"2023061309270201100_CIT0012","doi-asserted-by":"crossref","first-page":"e0178782","DOI":"10.1371\/journal.pone.0178782","article-title":"Chronotypes in the US\u2013influence of age and sex","volume":"12","author":"Fischer","year":"2017","journal-title":"PLoS One."},{"key":"2023061309270201100_CIT0013","doi-asserted-by":"crossref","first-page":"170","DOI":"10.3389\/fnagi.2017.00170","article-title":"Neurodegeneration and the circadian clock","volume":"9","author":"Hood","year":"2017","journal-title":"Front Aging Neurosci."},{"key":"2023061309270201100_CIT0014","doi-asserted-by":"crossref","first-page":"118","DOI":"10.3389\/fneur.2012.00118","article-title":"Age-related changes in sleep and circadian rhythms: impact on cognitive performance and underlying neuroanatomical networks","volume":"3","author":"Schmidt","year":"2012","journal-title":"Front Neurol."},{"issue":"2","key":"2023061309270201100_CIT0015","doi-asserted-by":"crossref","first-page":"487","DOI":"10.3233\/JAD-201573","article-title":"Unique sleep and circadian rhythm dysfunction neuroinflammatory and immune profiles in Alzheimer\u2019s disease with mild cognitive impairment","volume":"81","author":"Pillai","year":"2021","journal-title":"J Alzheimers Dis."},{"issue":"7","key":"2023061309270201100_CIT0016","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1017\/S1041610219001777","article-title":"Sleep-wake disorders in Alzheimer\u2019s disease: further genetic analyses in relation to objective sleep measures","volume":"32","author":"Yesavage","year":"2020","journal-title":"Int Psychogeriatr."},{"issue":"2","key":"2023061309270201100_CIT0017","doi-asserted-by":"crossref","first-page":"501","DOI":"10.3233\/JAD-191124","article-title":"Sleep-wake cycle in Alzheimer\u2019s disease is associated with tau pathology and orexin dysregulation","volume":"74","author":"Liguori","year":"2020","journal-title":"J Alzheimers Dis."},{"issue":"5","key":"2023061309270201100_CIT0018","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1001\/jamaneurol.2017.4719","article-title":"Circadian rest-activity pattern changes in aging and preclinical Alzheimer disease","volume":"75","author":"Musiek","year":"2018","journal-title":"JAMA Neurol"},{"key":"2023061309270201100_CIT0019","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.neubiorev.2019.07.019","article-title":"Alzheimer\u2019s disease: neurotransmitters of the sleep-wake cycle","volume":"105","author":"Van Erum","year":"2019","journal-title":"Neurosci Biobehav Rev."},{"issue":"2","key":"2023061309270201100_CIT0020","doi-asserted-by":"crossref","first-page":"89","DOI":"10.9758\/cpn.2017.15.2.89","article-title":"Role of sleep disturbance in the trajectory of Alzheimer\u2019s disease","volume":"15","author":"Kang","year":"2017","journal-title":"Clin Psychopharmacol Neurosci."},{"key":"2023061309270201100_CIT0021","doi-asserted-by":"crossref","first-page":"100065","DOI":"10.1016\/j.nbscr.2021.100065","article-title":"A population-based prospective study on rest-activity rhythm and mild cognitive impairment among Hong Kong healthy community-dwelling older adults","volume":"10","author":"Lee","year":"2021","journal-title":"Neurobiol Sleep Circadian Rhythms"},{"key":"2023061309270201100_CIT0022","doi-asserted-by":"crossref","first-page":"102881","DOI":"10.1016\/j.ebiom.2020.102881","article-title":"Associations of rest-activity patterns with amyloid burden, medial temporal lobe atrophy, and cognitive impairment","volume":"58","author":"Roh","year":"2020","journal-title":"EBioMedicine"},{"issue":"3","key":"2023061309270201100_CIT0023","doi-asserted-by":"crossref","first-page":"e96","DOI":"10.1016\/S2666-7568(20)30015-5","article-title":"Circadian disturbances in Alzheimer\u2019s disease progression: a prospective observational cohort study of community-based older adults","volume":"1","author":"Li","year":"2020","journal-title":"Lancet Healthy Longev"},{"issue":"3","key":"2023061309270201100_CIT0024","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1016\/j.yebeh.2008.06.002","article-title":"How to assess circadian rhythm in humans: a review of literature","volume":"13","author":"Hofstra","year":"2008","journal-title":"Epilepsy Behav."},{"issue":"1","key":"2023061309270201100_CIT0025","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-021-85817-y","article-title":"Effects of long sleep time and irregular sleep\u2013wake rhythm on cognitive function in older people","volume":"11","author":"Okuda","year":"2021","journal-title":"Sci Rep."},{"issue":"8","key":"2023061309270201100_CIT0026","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.3390\/brainsci11081003","article-title":"Sleep in normal aging, homeostatic and circadian regulation and vulnerability to sleep deprivation","volume":"11","author":"Taillard","year":"2021","journal-title":"Brain Sci"},{"issue":"10248","key":"2023061309270201100_CIT0027","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S0140-6736(20)30367-6","article-title":"Dementia prevention, intervention, and care: 2020 report of the Lancet Commission","volume":"396","author":"Livingston","year":"2020","journal-title":"Lancet"},{"issue":"6","key":"2023061309270201100_CIT0028","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1097\/YCO.0000000000000370","article-title":"The management of sleep disorders in dementia: an update","volume":"30","author":"Kinnunen","year":"2017","journal-title":"Curr Opin Psychiatry."},{"issue":"2","key":"2023061309270201100_CIT0029","doi-asserted-by":"crossref","first-page":"e20","DOI":"10.1093\/ije\/dyv316","article-title":"Cohort profile: the Korean genome and epidemiology study (KoGES) Consortium","volume":"46","author":"Kim","year":"2016","journal-title":"Int J Epidemiol."},{"issue":"2","key":"2023061309270201100_CIT0030","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0165-1781(89)90047-4","article-title":"The Pittsburgh Sleep Quality Index: a new instrument for \u00adpsychiatric practice and research","volume":"28","author":"Buysse","year":"1989","journal-title":"Psychiatry Res."},{"issue":"5","key":"2023061309270201100_CIT0031","doi-asserted-by":"crossref","first-page":"964","DOI":"10.5664\/jcsm.9072","article-title":"Sex differences in deterioration of sleep properties associated with aging: a 12-year longitudinal cohort study","volume":"17","author":"Kim","year":"2021","journal-title":"J Clin Sleep Med."},{"issue":"6","key":"2023061309270201100_CIT0032","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.smrv.2007.07.005","article-title":"Epidemiology of the human circadian clock","volume":"11","author":"Roenneberg","year":"2007","journal-title":"Sleep Med Rev."},{"key":"2023061309270201100_CIT0033","doi-asserted-by":"crossref","first-page":"29","DOI":"10.3389\/fninf.2013.00029","article-title":"Robust multi-site MR data processing: iterative optimization of bias correction, tissue classification, and registration","volume":"7","author":"Young Kim","year":"2013","journal-title":"Front Neuroinform"},{"key":"2023061309270201100_CIT0034","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1016\/j.neuroimage.2017.04.012","article-title":"Robust automated constellation-based landmark detection in human brain imaging","volume":"170","author":"Ghayoor","year":"2018","journal-title":"Neuroimage."},{"key":"2023061309270201100_CIT0035","doi-asserted-by":"crossref","first-page":"27","DOI":"10.3389\/fninf.2013.00027","article-title":"Multi-atlas segmentation with joint label fusion and corrective learning\u2014an open source implementation","volume":"7","author":"Wang","year":"2013","journal-title":"Front Neuroinform"},{"key":"2023061309270201100_CIT0036","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.neurobiolaging.2018.04.017","article-title":"Lifestyle-dependent brain change: a longitudinal cohort MRI study","volume":"69","author":"Kim","year":"2018","journal-title":"Neurobiol Aging."},{"issue":"11","key":"2023061309270201100_CIT0037","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1017\/S1041610217000990","article-title":"Cognitive performance norms from the Korean Genome and Epidemiology Study (KoGES)","volume":"29","author":"Kim","year":"2017","journal-title":"Int Psychogeriatr."},{"issue":"4","key":"2023061309270201100_CIT0038","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1080\/03610730490484380","article-title":"New norms for a new generation: cognitive performance in the Framingham Offspring Cohort","volume":"30","author":"Au","year":"2004","journal-title":"Exp Aging Res."},{"key":"2023061309270201100_CIT0039","volume-title":"Seoul Neuropsychological Screening Battery","author":"Kang","year":"2003"},{"issue":"9","key":"2023061309270201100_CIT0040","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1002\/gps.1570","article-title":"A normative study of the trail making test in Korean elders","volume":"21","author":"Seo","year":"2006","journal-title":"Int J Geriatr Psychiatry"},{"issue":"2","key":"2023061309270201100_CIT0041","first-page":"435","article-title":"A standardization study of the story recall test in the elderly Korean population","volume":"23","author":"An","year":"2004","journal-title":"Korean J Clin Lab"},{"issue":"11","key":"2023061309270201100_CIT0042","doi-asserted-by":"crossref","first-page":"2136","DOI":"10.1111\/jgs.15555","article-title":"Rest","volume":"66","author":"Rogers-Soeder","year":"2018","journal-title":"J Am Geriatr Soc."},{"key":"2023061309270201100_CIT0043","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2014\/524971","article-title":"The characterization of biological rhythms in mild cognitive impairment","volume":"2014","author":"Ortiz-Tudela","year":"2014","journal-title":"Biomed Res Int."},{"issue":"4","key":"2023061309270201100_CIT0044","doi-asserted-by":"crossref","first-page":"857","DOI":"10.3233\/JAD-131217","article-title":"Circadian misalignment and sleep disruption in mild cognitive impairment","volume":"38","author":"Naismith","year":"2014","journal-title":"J Alzheimers Dis."},{"key":"2023061309270201100_CIT0045","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.nlm.2018.05.017","article-title":"Medial temporal lobe atrophy relates more strongly to sleep-wake rhythm fragmentation than to age or any other known risk","volume":"160","author":"Van Someren","year":"2019","journal-title":"Neurobiol Learn Mem."},{"issue":"2","key":"2023061309270201100_CIT0046","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1038\/nn.3606","article-title":"Molecular drivers and cortical spread of lateral entorhinal cortex dysfunction in preclinical Alzheimer\u2019s disease","volume":"17","author":"Khan","year":"2014","journal-title":"Nat Neurosci."},{"issue":"5","key":"2023061309270201100_CIT0047","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1002\/hipo.20779","article-title":"A medial temporal lobe division of labor: insights from memory in aging and early Alzheimer disease","volume":"21","author":"Wolk","year":"2011","journal-title":"Hippocampus."},{"key":"2023061309270201100_CIT0048","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1016\/j.neuroimage.2017.05.049","article-title":"The association between tau PET and retrospective cortical thinning in clinically normal elderly","volume":"157","author":"LaPoint","year":"2017","journal-title":"Neuroimage."},{"issue":"338","key":"2023061309270201100_CIT0049","doi-asserted-by":"crossref","first-page":"338ra366","DOI":"10.1126\/scitranslmed.aaf2362","article-title":"Tau and A\u03b2 imaging, CSF measures, and cognition in Alzheimer\u2019s disease","volume":"8","author":"Brier","year":"2016","journal-title":"Sci Transl Med."},{"issue":"4","key":"2023061309270201100_CIT0050","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1007\/BF00308809","article-title":"Neuropathological stageing of Alzheimer-related changes","volume":"82","author":"Braak","year":"1991","journal-title":"Acta Neuropathol."},{"issue":"8","key":"2023061309270201100_CIT0051","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1080\/13854046.2013.836567","article-title":"Practice effects and longitudinal cognitive change in normal aging vs. incident mild cognitive impairment and dementia in the mayo clinic study of aging","volume":"27","author":"Machulda","year":"2013","journal-title":"Clin Neuropsychol."},{"issue":"4","key":"2023061309270201100_CIT0052","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1080\/13854046.2012.680913","article-title":"Scoring higher the second time around: meta-analyses of practice effects in neuropsychological assessment","volume":"26","author":"Calamia","year":"2012","journal-title":"Clin Neuropsychol."},{"issue":"9","key":"2023061309270201100_CIT0053","doi-asserted-by":"crossref","first-page":"1382","DOI":"10.1038\/s41401-020-00565-5","article-title":"New therapeutics beyond amyloid-\u03b2 and tau for the treatment of Alzheimer\u2019s disease","volume":"42","author":"Zhang","year":"2021","journal-title":"Acta Pharmacol Sin."},{"issue":"2","key":"2023061309270201100_CIT0054","doi-asserted-by":"crossref","first-page":"342","DOI":"10.3390\/clockssleep3020021","article-title":"Concordance of chronotype categorisations based on dim light melatonin onset, the Morningness-Eveningness Questionnaire, and the Munich Chronotype Questionnaire","volume":"3","author":"Reiter","year":"2021","journal-title":"Clocks Sleep"},{"key":"2023061309270201100_CIT0055","doi-asserted-by":"crossref","first-page":"166","DOI":"10.3389\/fnagi.2015.00166","article-title":"Measuring sleep quality in older adults: a comparison using subjective and objective methods","volume":"7","author":"Landry","year":"2015","journal-title":"Front Aging Neurosci."},{"issue":"3","key":"2023061309270201100_CIT0056","doi-asserted-by":"crossref","first-page":"665","DOI":"10.5665\/sleep.5548","article-title":"Changes in sleep duration and sleep timing associated with retirement transitions","volume":"39","author":"Hagen","year":"2016","journal-title":"Sleep."}],"container-title":["SLEEP"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/sleep\/advance-article-pdf\/doi\/10.1093\/sleep\/zsad108\/50188338\/zsad108.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/sleep\/article-pdf\/46\/6\/zsad108\/50562104\/zsad108.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/sleep\/article-pdf\/46\/6\/zsad108\/50562104\/zsad108.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,13]],"date-time":"2023-06-13T09:29:40Z","timestamp":1686648580000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/sleep\/article\/doi\/10.1093\/sleep\/zsad108\/7123764"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,15]]},"references-count":56,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2023,4,15]]},"published-print":{"date-parts":[[2023,6,13]]}},"URL":"https:\/\/doi.org\/10.1093\/sleep\/zsad108","relation":{},"ISSN":["0161-8105","1550-9109"],"issn-type":[{"value":"0161-8105","type":"print"},{"value":"1550-9109","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,6,1]]},"published":{"date-parts":[[2023,4,15]]},"article-number":"zsad108"}}