{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T19:06:04Z","timestamp":1790363164639,"version":"4.1.0"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2024,3,26]],"date-time":"2024-03-26T00:00:00Z","timestamp":1711411200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,6,13]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Study Objectives<\/jats:title>\n                  <jats:p>Recent studies suggest that sleepy patients with obstructive sleep apnea (OSA) are at higher risk for incident cardiovascular disease. This study assessed cardiac autonomic function in sleepy versus non-sleepy patients with OSA using heart rate variability (HRV) analysis. We hypothesized that HRV profiles of sleepy patients would indicate higher cardiovascular risk.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>Electrocardiograms (ECG) derived from polysomnograms (PSG) collected by the Sydney Sleep Biobank were used to study HRV in groups of sleepy (ESS\u2005\u2265\u200510) and non-sleepy OSA patients (ESS\u2005&amp;lt;\u200510). HRV parameters were averaged across available ECG signals during N2 sleep.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>A total of 421 patients were evaluated, with a mean age of 54 (14) years, body mass index of 33 (9) kg\/m2, apnea\u2013hypopnea index of 21 (28) events\/h, and 66% male. The sleepy group consisted of 119 patients and the non-sleepy group 302 patients. Sleepy patients exhibited lower HRV values for: root mean square successive difference (RMSSD, p\u2005=\u20050.028), total power (TP, p\u2005=\u20050.031), absolute low frequency (LF, p\u2005=\u20050.045), and high-frequency (HF, p\u2005=\u20050.010) power compared to non-sleepy patients. Sleepy patients with moderate-to-severe OSA exhibited lower HRV values for: (RMSSD, p\u2005=\u20050.045; TP, p\u2005=\u20050.052), absolute LF (p\u2005=\u20050.051), and HF power (p\u2005=\u20050.025). There were no differences in other time and frequency domain HRV markers.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>This study shows a trend toward parasympathetic withdrawal in sleepy OSA patients, particularly in moderate-to-severe cases, lending mechanistic support to the link between the sleepy phenotype and CVD risk in OSA.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/sleep\/zsae075","type":"journal-article","created":{"date-parts":[[2024,3,26]],"date-time":"2024-03-26T00:24:55Z","timestamp":1711412695000},"source":"Crossref","is-referenced-by-count":18,"title":["Heart rate variability analysis in obstructive sleep apnea patients with daytime sleepiness"],"prefix":"10.1093","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0002-741X","authenticated-orcid":false,"given":"Seren","family":"Ucak","sequence":"first","affiliation":[{"name":"Charles Perkins Centre and Northern Clinical School, Faculty of Medicine and Health, University of Sydney , Sydney, NSW , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8349-4066","authenticated-orcid":false,"given":"Hasthi U","family":"Dissanayake","sequence":"additional","affiliation":[{"name":"Charles Perkins Centre and Northern Clinical School, Faculty of Medicine and Health, University of Sydney , Sydney, NSW , Australia"},{"name":"Department of Respiratory and Sleep Medicine, Royal North Shore Hospital , Sydney, NSW , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2091-207X","authenticated-orcid":false,"given":"Philip","family":"de Chazal","sequence":"additional","affiliation":[{"name":"Charles Perkins Centre and Northern Clinical School, Faculty of Medicine and Health, University of Sydney , Sydney, NSW , Australia"},{"name":"School of Biomedical Engineering, Faculty of Engineering, University of Sydney , Sydney, NSW , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4954-2658","authenticated-orcid":false,"given":"Yu Sun","family":"Bin","sequence":"additional","affiliation":[{"name":"Charles Perkins Centre and Northern Clinical School, Faculty of Medicine and Health, University of Sydney , Sydney, NSW , Australia"},{"name":"Department of Respiratory and Sleep Medicine, Royal North Shore Hospital , Sydney, NSW , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6106-7303","authenticated-orcid":false,"given":"Kate","family":"Sutherland","sequence":"additional","affiliation":[{"name":"Charles Perkins Centre and Northern Clinical School, Faculty of Medicine and Health, University of Sydney , Sydney, NSW , Australia"},{"name":"Department of Respiratory and Sleep Medicine, Royal North Shore Hospital , Sydney, NSW , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-3186-8657","authenticated-orcid":false,"given":"Bianca","family":"Setionago","sequence":"additional","affiliation":[{"name":"Charles Perkins Centre and Northern Clinical School, Faculty of Medicine and Health, University of Sydney , Sydney, NSW , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0554-5221","authenticated-orcid":false,"given":"Benjamin","family":"Tong","sequence":"additional","affiliation":[{"name":"Charles Perkins Centre and Northern Clinical School, Faculty of Medicine and Health, University of Sydney , Sydney, NSW , Australia"},{"name":"Department of Respiratory and Sleep Medicine, Royal North Shore Hospital , Sydney, NSW , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2196-8649","authenticated-orcid":false,"given":"Brendon J","family":"Yee","sequence":"additional","affiliation":[{"name":"Sydney Medical School, Faculty of Medicine and Health, University of Sydney , Sydney, NSW , Australia"},{"name":"Woolcock Institute of Medical Research, Royal Prince Alfred Hospital , Sydney, NSW , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8808-3183","authenticated-orcid":false,"given":"Kristina","family":"Kairaitis","sequence":"additional","affiliation":[{"name":"Sydney Medical School, Faculty of Medicine and Health, University of Sydney , Sydney, NSW , Australia"},{"name":"Ludwig Engel Centre for Respiratory Research, Westmead Institute for Medical Research , Sydney, NSW , Australia"},{"name":"Department of Respiratory and Sleep Medicine, Westmead Hospital , Sydney, NSW , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1605-8843","authenticated-orcid":false,"given":"John R","family":"Wheatley","sequence":"additional","affiliation":[{"name":"Sydney Medical School, Faculty of Medicine and Health, University of Sydney , Sydney, NSW , Australia"},{"name":"Ludwig Engel Centre for Respiratory Research, Westmead Institute for Medical Research , Sydney, NSW , Australia"},{"name":"Department of Respiratory and Sleep Medicine, Westmead Hospital , Sydney, NSW , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda J","family":"Piper","sequence":"additional","affiliation":[{"name":"Sydney Medical School, Faculty of Medicine and Health, University of Sydney , Sydney, NSW , Australia"},{"name":"Department of Respiratory and Sleep Medicine, Royal Prince Alfred Hospital , Sydney, NSW , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7920-4924","authenticated-orcid":false,"given":"Peter A","family":"Cistulli","sequence":"additional","affiliation":[{"name":"Charles Perkins Centre and Northern Clinical School, Faculty of Medicine and Health, University of Sydney , Sydney, NSW , Australia"},{"name":"Department of Respiratory and Sleep Medicine, Royal North Shore Hospital , Sydney, NSW , Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"Sydney Sleep Biobank Investigators","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Cistulli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"de Chazal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kate","family":"Sutherland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina","family":"Sarkissian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chin","family":"Moi Chow","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aimee","family":"Lowth","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacob","family":"Graham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Wood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary","family":"Cohen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Callum","family":"Bennett","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Ahmadi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Wheatley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristina","family":"Kairaitis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Lambert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rita","family":"Ginn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tracey","family":"Burns","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brendon","family":"Yee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Piper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keith","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerri","family":"Melehan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gislaine","family":"Gauthier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,3,26]]},"reference":[{"issue":"3","key":"2024061223514364200_CIT0001","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1164\/ajrccm.158.3.9711033","article-title":"Sleep fragmentation indices as predictors of daytime sleepiness and nCPAP response in obstructive sleep apnea","volume":"158","author":"Bennett","year":"1998","journal-title":"Am J Respir Crit Care Med."},{"issue":"6","key":"2024061223514364200_CIT0002","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1378\/chest.100.6.1542","article-title":"Hypoxemia vs sleep fragmentation as cause of excessive daytime sleepiness in obstructive sleep apnea","volume":"100","author":"Colt","year":"1991","journal-title":"Chest."},{"issue":"4","key":"2024061223514364200_CIT0003","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1164\/rccm.201808-1509OC","article-title":"Symptom subtypes of obstructive sleep apnea predict incidence of cardiovascular outcomes","volume":"200","author":"Mazzotti","year":"2019","journal-title":"Am J Respir Crit Care Med."},{"issue":"3","key":"2024061223514364200_CIT0004","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1111\/j.1365-2869.2008.00659.x","article-title":"Daytime sleepiness and neural cardiac modulation in sleep-related breathing disorders","volume":"17","author":"Lombardi","year":"2008","journal-title":"J Sleep Res."},{"issue":"3","key":"2024061223514364200_CIT0005","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1111\/j.1365-2869.2007.00602.x","article-title":"Daytime sympathetic hyperactivity in OSAS is related to excessive daytime sleepiness","volume":"16","author":"Donadio","year":"2007","journal-title":"J Sleep Res."},{"issue":"2","key":"2024061223514364200_CIT0006","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/j.1542-474X.1996.tb00275.x","article-title":"Heart rate variability: standards of measurement, physiological interpretation, and clinical use: task force of the European Society of Cardiology and the North American Society for Pacing and Electrophysiology","volume":"1","author":"Malik","year":"1996","journal-title":"Ann Noninvasive Electrocardiol."},{"key":"2024061223514364200_CIT0007","first-page":"25","article-title":"Sydney Sleep Biobank (SSB): Development of a Research Resource","volume":"28","author":"Sutherland","year":"2019","journal-title":"J Sleep Res."},{"key":"2024061223514364200_CIT0008","first-page":"665","article-title":"AASM scoring manual updates for 2017 (version 2.4). J Clin Sleep Med","author":"Berry","year":"2017"},{"key":"2024061223514364200_CIT0009","doi-asserted-by":"crossref","first-page":"642333","DOI":"10.3389\/fpsyt.2021.642333","article-title":"The different facets of heart rate variability in obstructive sleep apnea","volume":"12","author":"Qin","year":"2021","journal-title":"Front Psychiatry."},{"issue":"4","key":"2024061223514364200_CIT0010","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1007\/s10840-022-01202-3","article-title":"Does obstructive sleep apnoea modulate cardiac autonomic function in paroxysmal atrial fibrillation","volume":"66","author":"Mohammadieh","year":"2023","journal-title":"J Interv Card Electrophysiol."},{"issue":"2","key":"2024061223514364200_CIT0011","doi-asserted-by":"crossref","first-page":"144","DOI":"10.4097\/kjae.2017.70.2.144","article-title":"Central limit theorem: the cornerstone of modern statistics","volume":"70","author":"Kwak","year":"2017","journal-title":"Korean J Anesthesiol."},{"issue":"4","key":"2024061223514364200_CIT0012","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1177\/0004563221992088","article-title":"Best practice in statistics: use the Welch t-test when testing the difference between two groups","volume":"58","author":"West","year":"2021","journal-title":"Ann Clin Biochem."},{"issue":"1","key":"2024061223514364200_CIT0013","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1111\/j.1542-474X.2005.10101.x","article-title":"Heart rate variability: measurement and clinical utility","volume":"10","author":"Kleiger","year":"2005","journal-title":"Ann Noninvasive Electrocardiol."},{"key":"2024061223514364200_CIT0014","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1513\/AnnalsATS.202208-676OC","article-title":"Cardiovascular outcomes in adults with coronary artery disease and obstructive sleep apnea with vs without excessive daytime sleepiness in the RICCADSA cohort","volume":"20","author":"Eulenburg","year":"2023","journal-title":"Ann Am Thorac Soc."},{"issue":"6","key":"2024061223514364200_CIT0015","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1164\/rccm.202111-2608OC","article-title":"Cardiovascular benefit of continuous positive airway pressure in adults with coronary artery disease and obstructive sleep apnea without excessive sleepiness","volume":"206","author":"Azarbarzin","year":"2022","journal-title":"Am J Respir Crit Care Med."},{"key":"2024061223514364200_CIT0016","doi-asserted-by":"crossref","first-page":"86","DOI":"10.3389\/fphys.2011.00086","article-title":"Heart rate variability \u2013 a historical perspective","volume":"2","author":"Billman","year":"2011","journal-title":"Front Physiol."},{"issue":"12","key":"2024061223514364200_CIT0017","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1113\/expphysiol.2010.056259","article-title":"Low-frequency power of heart rate variability is not a measure of cardiac sympathetic tone but may be a measure of modulation of cardiac autonomic outflows by baroreflexes","volume":"96","author":"Goldstein","year":"2011","journal-title":"Exp Physiol."},{"key":"2024061223514364200_CIT0018","doi-asserted-by":"crossref","first-page":"357","DOI":"10.3389\/fpsyt.2018.00357","article-title":"Cognitive impairment and affective disorders in patients with obstructive sleep apnea syndrome","volume":"9","author":"Bilyukov","year":"2018","journal-title":"Front Psychiatry."},{"key":"2024061223514364200_CIT0019","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1007\/s11325-011-0515-z","article-title":"Polysomnographic characteristics of daytime sleepiness in obstructive sleep apnea syndrome","volume":"16","author":"Sun","year":"2012","journal-title":"Sleep Breath."},{"issue":"1","key":"2024061223514364200_CIT0020","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1183\/09031936.00009506","article-title":"Daytime sleepiness and polysomnographic variables in sleep apnoea patients","volume":"30","author":"Mediano","year":"2007","journal-title":"Eur Respir J."},{"issue":"2","key":"2024061223514364200_CIT0021","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1164\/ajrccm.159.2.9804051","article-title":"Relation of sleepiness to respiratory disturbance index: the Sleep Heart Health Study","volume":"159","author":"Gottlieb","year":"1999","journal-title":"Am J Respir Crit Care Med."},{"issue":"3","key":"2024061223514364200_CIT0022","doi-asserted-by":"crossref","first-page":"271","DOI":"10.5664\/jcsm.3526","article-title":"Relationship of heart rate variability to sleepiness in patients with obstructive sleep apnea with and without heart failure","volume":"10","author":"Taranto Montemurro","year":"2014","journal-title":"J Clin Sleep Med."},{"issue":"8","key":"2024061223514364200_CIT0023","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1016\/j.sleep.2015.03.010","article-title":"Prevalence and determinants of subjective sleepiness in healthy elderly with unrecognized obstructive sleep apnea","volume":"16","author":"Sforza","year":"2015","journal-title":"Sleep Med."},{"key":"2024061223514364200_CIT0024","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.ijcard.2017.01.149","article-title":"Excessive daytime sleepiness does not correlate with sympathetic nervous system activation and arterial stiffening in patients with mild-to-moderate obstructive sleep apnoea: a proof-of-principle study","volume":"236","author":"Bisogni","year":"2017","journal-title":"Int J Cardiol."},{"issue":"6","key":"2024061223514364200_CIT0025","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1183\/09031936.00032314","article-title":"The different clinical faces of obstructive sleep apnoea: a cluster analysis","volume":"44","author":"Ye","year":"2014","journal-title":"Eur Respir J."},{"issue":"3","key":"2024061223514364200_CIT0026","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1007\/s11325-022-02683-2","article-title":"Identifying phenotypes of obstructive sleep apnea using cluster analysis","volume":"27","author":"Venkatnarayan","year":"2023","journal-title":"Sleep Breath."},{"issue":"6","key":"2024061223514364200_CIT0027","doi-asserted-by":"crossref","first-page":"2266","DOI":"10.1016\/j.chest.2021.06.047","article-title":"A validation study of four different cluster analyses of OSA and the incidence of cardiovascular mortality in a Hispanic population","volume":"160","author":"Labarca","year":"2021","journal-title":"Chest."},{"issue":"6","key":"2024061223514364200_CIT0028","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1042\/CS20130332","article-title":"Statins and the autonomic nervous system","volume":"126","author":"Millar","year":"2014","journal-title":"Clin Sci (Lond)."},{"issue":"3","key":"2024061223514364200_CIT0029","first-page":"129","article-title":"The effect of the year angiotensin-converting enzyme inhibitors (ACE I) intake on circadian heart rate variability in patients with primary hypertension","volume":"42","author":"Banach","year":"2001","journal-title":"Folia Med Cracov."},{"issue":"1","key":"2024061223514364200_CIT0030","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/S0008-6363(97)00091-6","article-title":"Aldosterone blockade reduces vascular collagen turnover, improves heart rate variability and reduces early morning rise in heart rate in heart failure patients","volume":"35","author":"MacFadyen","year":"1997","journal-title":"Cardiovasc Res."},{"issue":"2","key":"2024061223514364200_CIT0031","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0002-9149(02)03098-9","article-title":"Effects of propranolol on recovery of heart rate variability following acute myocardial infarction and relation to outcome in the Beta-Blocker Heart Attack Trial","volume":"91","author":"Lampert","year":"2003","journal-title":"Am J Cardiol."},{"issue":"1","key":"2024061223514364200_CIT0032","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.jpsychores.2004.05.004","article-title":"Comparing MSLT and ESS in the measurement of excessive daytime sleepiness in obstructive sleep apnoea syndrome","volume":"58","author":"Fong","year":"2005","journal-title":"J Psychosom Res."},{"issue":"4","key":"2024061223514364200_CIT0033","doi-asserted-by":"crossref","first-page":"e0122645","DOI":"10.1371\/journal.pone.0122645","article-title":"Regularity of cardiac rhythm as a marker of sleepiness in sleep disordered breathing","volume":"10","author":"Guaita","year":"2015","journal-title":"PLoS One."},{"issue":"3","key":"2024061223514364200_CIT0034","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1046\/j.1365-201X.2003.01091.x","article-title":"Sympathetic nerve activity in obstructive sleep apnoea","volume":"177","author":"Narkiewicz","year":"2003","journal-title":"Acta Physiol Scand."},{"issue":"2","key":"2024061223514364200_CIT0035","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/S0002-9149(99)00638-4","article-title":"Comparison of autonomic withdrawal in men with obstructive sleep apnea syndrome, systemic hypertension, and neither condition","volume":"85","author":"Salo","year":"2000","journal-title":"Am J Cardiol."},{"issue":"7","key":"2024061223514364200_CIT0036","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1111\/resp.13064","article-title":"Co-morbid OSA and insomnia increases depression prevalence and severity in men","volume":"22","author":"Lang","year":"2017","journal-title":"Respirology."}],"container-title":["SLEEP"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/sleep\/advance-article-pdf\/doi\/10.1093\/sleep\/zsae075\/57338825\/zsae075.pdf","content-type":"application\/pdf","content-version":"am","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/sleep\/article-pdf\/47\/6\/zsae075\/57884192\/zsae075.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/sleep\/article-pdf\/47\/6\/zsae075\/57884192\/zsae075.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T00:57:09Z","timestamp":1718240229000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/sleep\/article\/doi\/10.1093\/sleep\/zsae075\/7635458"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,26]]},"references-count":36,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2024,3,26]]},"published-print":{"date-parts":[[2024,6,13]]}},"URL":"https:\/\/doi.org\/10.1093\/sleep\/zsae075","relation":{},"ISSN":["0161-8105","1550-9109"],"issn-type":[{"value":"0161-8105","type":"print"},{"value":"1550-9109","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,6,1]]},"published":{"date-parts":[[2024,3,26]]},"article-number":"zsae075"}}