{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T20:46:09Z","timestamp":1792097169331,"version":"4.4.0"},"reference-count":44,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2025,4,17]],"date-time":"2025-04-17T00:00:00Z","timestamp":1744848000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"funder":[{"DOI":"10.13039\/100000968","name":"American Heart Association","doi-asserted-by":"publisher","award":["17SFRN33590069 and 17SFRN33560006"],"award-info":[{"award-number":["17SFRN33590069 and 17SFRN33560006"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["K23DK133690"],"award-info":[{"award-number":["K23DK133690"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Study Objectives<\/jats:title>\n                    <jats:p>Time-restricted eating (TRE) is a novel dietary intervention targeting weight loss and cardiometabolic risk factors. The impact of TRE on sleep patterns remains under-explored.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a post hoc analysis of a parallel-arm, controlled feeding trial in 41 adults with obesity and prediabetes\/diabetes, randomized to TRE (08:00 am\u201306:00 pm) or usual eating pattern (UEP; 08:00 am\u201312:00 am) for 12 weeks. We objectively determined sleep\u2013wake patterns from 7-day wrist actigraphy data obtained at baseline and week 12. From this data, we derived total sleep time (TST) and sleep midpoint over a 24-hour period, sleep onset\/offset, and sleep continuity measures. We used paired t-tests or Wilcoxon signed rank tests to compare data between baseline and week 12 within intervention arms and Mann\u2013Whitney U tests or Wilcoxon signed rank tests to compare changes between intervention arms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>38 participants (20 UEP; 18 TRE; 93% of those randomized in the parent trial) with adequate actigraphy data (mean age 59.6\u2005\u00b1\u20057.3 years, 92% female, 92% Black, mean BMI 36.3\u2005\u00b1\u20054.7\u00a0kg\/m2) were analyzed. Compared to UEP, TRE increased TST by 55 minutes (p\u2005=\u2005.03). TRE shifted sleep midpoint to 44 minutes earlier, from 03:24 am to 02:40 am (p\u2005=\u2005.01), while UEP maintained the same sleep midpoint at 03:15 am. Sleep onset shifted from a median of 12:22 am to 11:52 pm in TRE (p\u2005=\u2005.03) while it remained stable in UEP (p\u2005=\u2005.97). There were no differences in sleep offset and sleep continuity within and between intervention arms.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>TRE increased sleep time and caused earlier sleep onset compared to UEP, revealing how the timing of eating may affect sleep timing and duration.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Trial<\/jats:title>\n                    <jats:p>The Time Restricted Intake of Meals Study (TRIM). URL: https:\/\/clinicaltrials.gov\/study\/NCT03527368?tab=history&amp;a=4<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Registration<\/jats:title>\n                    <jats:p>NCT03527368.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/sleep\/zsaf089","type":"journal-article","created":{"date-parts":[[2025,3,31]],"date-time":"2025-03-31T16:28:39Z","timestamp":1743438519000},"source":"Crossref","is-referenced-by-count":1,"title":["Effects of time-restricted eating on actigraphy-derived sleep parameters: post hoc analysis of a randomized, isocaloric feeding study"],"prefix":"10.1093","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4392-3206","authenticated-orcid":false,"given":"Daisy","family":"Duan","sequence":"first","affiliation":[{"name":"Division of Endocrinology, Diabetes, and Metabolism, Johns Hopkins University School of Medicine , Baltimore, MD 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