{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T09:04:20Z","timestamp":1769159060164,"version":"3.49.0"},"reference-count":62,"publisher":"Oxford University Press (OUP)","issue":"10","funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["5 R01 HL102321-02"],"award-info":[{"award-number":["5 R01 HL102321-02"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["P01 HL095491"],"award-info":[{"award-number":["P01 HL095491"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,10,1]]},"DOI":"10.1093\/sleep\/zsx128","type":"journal-article","created":{"date-parts":[[2017,7,23]],"date-time":"2017-07-23T05:53:42Z","timestamp":1500789222000},"source":"Crossref","is-referenced-by-count":8,"title":["Stable Breathing in Patients With Obstructive Sleep Apnea Is Associated With Increased Effort but Not Lowered Metabolic Rate"],"prefix":"10.1093","volume":"40","author":[{"given":"Camila M","family":"de Melo","sequence":"first","affiliation":[{"name":"Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, MA;"},{"name":"Department of Psychobiology, Universidade Federal de Sao Paulo UNIFESP, Sao Paulo, SP, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luigi","family":"Taranto-Montemurro","sequence":"additional","affiliation":[{"name":"Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, MA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James P","family":"Butler","sequence":"additional","affiliation":[{"name":"Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, MA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David P","family":"White","sequence":"additional","affiliation":[{"name":"Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, MA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen H","family":"Loring","sequence":"additional","affiliation":[{"name":"Department of Anesthesia and Critical Care, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Azarbarzin","sequence":"additional","affiliation":[{"name":"Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, MA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melania","family":"Marques","sequence":"additional","affiliation":[{"name":"Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, MA;"},{"name":"Sleep Laboratory, Pulmonary Division, Heart Institute (Incor), Hospital das Cl\u00ednicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip J","family":"Berger","sequence":"additional","affiliation":[{"name":"The Ritchie Centre, Hudson Institute of Medical Research, Monash University, Melbourne, VIC, Australia;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Wellman","sequence":"additional","affiliation":[{"name":"Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, MA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott A","family":"Sands","sequence":"additional","affiliation":[{"name":"Division of Sleep and Circadian Disorders, Departments of Medicine and Neurology, Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, MA;"},{"name":"Department of Allergy Immunology and Respiratory Medicine and Central Clinical School, The Alfred and Monash University, Melbourne, VIC, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2017,7,23]]},"reference":[{"issue":"6","key":"key\n\t\t\t\t20180328152816_CIT0001","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1164\/rccm.200302-201OC","article-title":"Contributions of upper airway mechanics and control mechanisms to severity of obstructive apnea","volume":"168","author":"Younes","year":"2003","journal-title":"Am J Respir Crit Care Med"},{"issue":"6","key":"key\n\t\t\t\t20180328152816_CIT0002","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1152\/japplphysiol.00972.2010","article-title":"A method for measuring and modeling the physiological traits causing obstructive sleep apnea","volume":"110","author":"Wellman","year":"2011","journal-title":"J Appl Physiol (1985)"},{"issue":"7","key":"key\n\t\t\t\t20180328152816_CIT0003","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1152\/japplphysiol.00747.2012","article-title":"A simplified method for determining phenotypic traits in patients with obstructive sleep apnea","volume":"114","author":"Wellman","year":"2013","journal-title":"J Appl Physiol (1985)"},{"issue":"5","key":"key\n\t\t\t\t20180328152816_CIT0004","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1164\/ajrccm.163.5.2007013","article-title":"Chemical control stability in patients with obstructive sleep apnea","volume":"163","author":"Younes","year":"2001","journal-title":"Am J Respir Crit Care Med"},{"issue":"3","key":"key\n\t\t\t\t20180328152816_CIT0005","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1093\/sleep\/32.3.361","article-title":"Airway dilator muscle activity and lung volume during stable breathing in obstructive sleep apnea","volume":"32","author":"Jordan","year":"2009","journal-title":"Sleep"},{"issue":"6 Pt 1","key":"key\n\t\t\t\t20180328152816_CIT0006","first-page":"E1036","article-title":"Energy expenditure in obstructive sleep apnea: effects of treatment with continuous positive airway pressure","volume":"271","author":"Stenl\u00f6f","year":"1996","journal-title":"Am J Physiol"},{"issue":"8","key":"key\n\t\t\t\t20180328152816_CIT0007","doi-asserted-by":"crossref","first-page":"833","DOI":"10.2169\/internalmedicine.50.4779","article-title":"Resting metabolic rate and anthropometric measurements in male sleep apnea patients","volume":"50","author":"Ucok","year":"2011","journal-title":"Intern Med"},{"issue":"1","key":"key\n\t\t\t\t20180328152816_CIT0008","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/s11325-015-1194-y","article-title":"Resting energy expenditure in OSAS: the impact of a single CPAP application","volume":"20","author":"Fekete","year":"2015","journal-title":"Sleep Breat"},{"issue":"5","key":"key\n\t\t\t\t20180328152816_CIT0009","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1053\/meta.2002.31969","article-title":"Effects of treatment by laser-assisted uvuloplasty on sleep energy expenditure in obstructive sleep apnea patients","volume":"51","author":"Lin","year":"2002","journal-title":"Metabolism"},{"issue":"5 Pt 1","key":"key\n\t\t\t\t20180328152816_CIT0010","first-page":"E732","article-title":"Relationship between sleep stages and metabolic rate in humans","volume":"267","author":"Fontvieille","year":"1994","journal-title":"Am J Physiol"},{"issue":"6","key":"key\n\t\t\t\t20180328152816_CIT0011","doi-asserted-by":"crossref","first-page":"519","DOI":"10.5664\/jcsm.27651","article-title":"Marked reduction in obstructive sleep apnea severity in slow wave sleep","volume":"5","author":"Ratnavadivel","year":"2009","journal-title":"J Clin Sleep Med"},{"issue":"3","key":"key\n\t\t\t\t20180328152816_CIT0012","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1183\/09031936.02.00262002","article-title":"Arousability in sleep apnoea\/hypopnoea syndrome patients","volume":"20","author":"Dingli","year":"2002","journal-title":"Eur Respir J"},{"issue":"4","key":"key\n\t\t\t\t20180328152816_CIT0013","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1152\/jappl.1968.24.4.503","article-title":"Metabolic depression and oxygen depletion in the diving turtle","volume":"24","author":"Jackson","year":"1968","journal-title":"J Appl Physiol"},{"issue":"6 Pt 2","key":"key\n\t\t\t\t20180328152816_CIT0014","first-page":"R1040","article-title":"Metabolism and ventilation in acute hypoxia: a comparative analysis in small mammalian species","volume":"262","author":"Frappell","year":"1992","journal-title":"Am J Physiol"},{"issue":"4","key":"key\n\t\t\t\t20180328152816_CIT0015","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1177\/0271678X15605855","article-title":"Cerebral metabolic rate of oxygen in obstructive sleep apnea at rest and in response to breath-hold challenge","volume":"36","author":"Rodgers","year":"2016","journal-title":"J Cereb Blood Flow Metab"},{"issue":"5","key":"key\n\t\t\t\t20180328152816_CIT0016","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.1183\/13993003.00823-2016","article-title":"Desipramine improves upper airway collapsibility and reduces obstructive sleep apnoea severity in patients with minimal muscle compensation","volume":"48","author":"Taranto-Montemurro","year":"2016","journal-title":"Eur Respir J"},{"key":"key\n\t\t\t\t20180328152816_CIT0017","first-page":"11","article-title":"Ventilation","volume-title":"Respiratory Physiology: The Essentials","author":"West","year":"1985"},{"issue":"2","key":"key\n\t\t\t\t20180328152816_CIT0018","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1164\/rccm.167.2.211","article-title":"ATS\/ACCP Statement on cardiopulmonary exercise testing","volume":"167","author":"American Thoracic Society; American College of Chest Physicians","year":"2003","journal-title":"Am J Respir Crit Care Med"},{"issue":"3","key":"key\n\t\t\t\t20180328152816_CIT0019","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1097\/00003246-199903000-00030","article-title":"Effects of ventilator resetting on indirect calorimetry measurement in the critically ill surgical patient","volume":"27","author":"Brandi","year":"1999","journal-title":"Crit Care Med"},{"issue":"2","key":"key\n\t\t\t\t20180328152816_CIT0020","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1152\/physrev.1970.50.2.196","article-title":"Oxygen and carbon dioxide gas stores of the body","volume":"50","author":"Cherniack","year":"1970","journal-title":"Physiol Rev"},{"issue":"4","key":"key\n\t\t\t\t20180328152816_CIT0021","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1152\/jappl.1985.58.4.1263","article-title":"Pressure-time product, flow, and oxygen cost of resistive breathing in humans","volume":"58","author":"Collett","year":"1985","journal-title":"J Appl Physiol (1985)"},{"key":"key\n\t\t\t\t20180328152816_CIT0022","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.00615-2016","article-title":"Control theory prediction of resolved cheyne-stokes respiration in heart failure","author":"Sands","year":"2016","journal-title":"Eur Respir J"},{"issue":"3","key":"key\n\t\t\t\t20180328152816_CIT0023","doi-asserted-by":"crossref","first-page":"511","DOI":"10.5665\/sleep.5516","article-title":"Upper airway collapsibility (Pcrit) and pharyngeal dilator muscle activity are sleep stage dependent","volume":"39","author":"Carberry","year":"2016","journal-title":"Sleep"},{"issue":"4","key":"key\n\t\t\t\t20180328152816_CIT0024","doi-asserted-by":"crossref","first-page":"555","DOI":"10.5665\/sleep.2544","article-title":"A mechanism for upper airway stability during slow wave sleep","volume":"36","author":"McSharry","year":"2013","journal-title":"Sleep"},{"issue":"2","key":"key\n\t\t\t\t20180328152816_CIT0025","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1136\/thx.2008.112953","article-title":"Upper airway function and arousability to ventilatory challenge in slow wave versus stage 2 sleep in obstructive sleep apnoea","volume":"65","author":"Ratnavadivel","year":"2010","journal-title":"Thorax"},{"issue":"2","key":"key\n\t\t\t\t20180328152816_CIT0026","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1164\/ajrccm.150.2.8049832","article-title":"Flow limitation as a noninvasive assessment of residual upper-airway resistance during continuous positive airway pressure therapy of obstructive sleep apnea","volume":"150","author":"Condos","year":"1994","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"key\n\t\t\t\t20180328152816_CIT0027","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1164\/rccm.201604-0761OC","article-title":"Resonance as the mechanism of daytime periodic breathing in patients with heart failure","volume":"195","author":"Sands","year":"2017","journal-title":"Am J Respir Crit Care Med"},{"issue":"5","key":"key\n\t\t\t\t20180328152816_CIT0028","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1152\/japplphysiol.90408.2008","article-title":"Role of respiratory control mechanisms in the pathogenesis of obstructive sleep disorders","volume":"105","author":"Younes","year":"2008","journal-title":"J Appl Physiol (1985)"},{"issue":"1","key":"key\n\t\t\t\t20180328152816_CIT0029","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1093\/europace\/euv122","article-title":"Intrathoracic pressure swings induced by simulated obstructive sleep apnoea promote arrhythmias in paroxysmal atrial fibrillation","volume":"18","author":"Schlatzer","year":"2016","journal-title":"Europace"},{"issue":"6","key":"key\n\t\t\t\t20180328152816_CIT0030","first-page":"1718","article-title":"Reduced stroke volume related to pleural pressure in obstructive sleep apnea","volume":"55","author":"Tolle","year":"1983","journal-title":"J Appl Physiol Respir Environ Exerc Physiol"},{"issue":"9","key":"key\n\t\t\t\t20180328152816_CIT0031","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.1016\/j.hrthm.2011.03.053","article-title":"Negative tracheal pressure during obstructive respiratory events promotes atrial fibrillation by vagal activation","volume":"8","author":"Linz","year":"2011","journal-title":"Heart Rhythm"},{"issue":"1","key":"key\n\t\t\t\t20180328152816_CIT0032","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/0034-5687(89)90021-2","article-title":"Diaphragm VO2, diaphragm EMG, pressure-time product and calculated ventilation in newborn lambs during hypercapnic hyperpnoea","volume":"76","author":"Soust","year":"1989","journal-title":"Respir Physiol"},{"issue":"1","key":"key\n\t\t\t\t20180328152816_CIT0033","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1172\/JCI108619","article-title":"The relationship of respiratory failure to the oxygen consumption of, lactate production by, and distribution of blood flow among respiratory muscles during increasing inspiratory resistance","volume":"59","author":"Robertson","year":"1977","journal-title":"J Clin Invest"},{"issue":"3","key":"key\n\t\t\t\t20180328152816_CIT0034","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1164\/ajrccm.160.3.9902058","article-title":"The impact of morbid obesity on oxygen cost of breathing (VO(2RESP)) at rest","volume":"160","author":"Kress","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"issue":"2","key":"key\n\t\t\t\t20180328152816_CIT0035","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1152\/jappl.1991.70.2.895","article-title":"Metabolic and respiratory effects of flow-resistive loading in preterm infants","volume":"70","author":"Duara","year":"1991","journal-title":"J Appl Physiol (1985)"},{"issue":"3 Pt 2","key":"key\n\t\t\t\t20180328152816_CIT0036","first-page":"R632","article-title":"Metabolic rate, respiratory exchange ratio, and apneas during meditation","volume":"256","author":"Kesterson","year":"1989","journal-title":"Am J Physiol"},{"issue":"4","key":"key\n\t\t\t\t20180328152816_CIT0037","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1152\/jappl.1988.64.4.1624","article-title":"Cardiac output and O2 consumption during inspiratory threshold loaded breathing","volume":"64","author":"Coast","year":"1988","journal-title":"J Appl Physiol (1985)"},{"issue":"6","key":"key\n\t\t\t\t20180328152816_CIT0038","doi-asserted-by":"crossref","first-page":"2518","DOI":"10.1152\/jappl.1988.65.6.2518","article-title":"O2 cost of inspiratory and expiratory resistive breathing in humans","volume":"65","author":"Dodd","year":"1988","journal-title":"J Appl Physiol (1985)"},{"issue":"3","key":"key\n\t\t\t\t20180328152816_CIT0039","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1111\/j.1469-445X.1999.01884.x","article-title":"The Joan Mott Prize Lecture. The integrated response to hypoxia: from circulation to cells","volume":"84","author":"Marshall","year":"1999","journal-title":"Exp Physiol"},{"issue":"5","key":"key\n\t\t\t\t20180328152816_CIT0040","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1111\/j.1475-097X.1987.tb00179.x","article-title":"Human cardiovascular adjustments to acute hypoxaemia","volume":"7","author":"Rowell","year":"1987","journal-title":"Clin Physiol"},{"issue":"1","key":"key\n\t\t\t\t20180328152816_CIT0041","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1186\/1743-7075-9-103","article-title":"Post-metabolic response to passive normobaric hypoxic exposure in sedendary overweight males: a pilot study","volume":"9","author":"Workman","year":"2012","journal-title":"Nutr Metab (Lond)"},{"issue":"6","key":"key\n\t\t\t\t20180328152816_CIT0042","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1164\/rccm.201511-2314OC","article-title":"Changes in energy metabolism after continuous positive airway pressure for obstructive sleep apnea","volume":"194","author":"Tachikawa","year":"2016","journal-title":"Am J Respir Crit Care Med"},{"issue":"6","key":"key\n\t\t\t\t20180328152816_CIT0043","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1016\/j.orcp.2015.08.015","article-title":"Effects of CPAP on energy expenditure in obese obstructive sleep apnoea patients: a pilot study","volume":"9","author":"Shechter","year":"2015","journal-title":"Obes Res Clin Pract"},{"issue":"8","key":"key\n\t\t\t\t20180328152816_CIT0044","doi-asserted-by":"crossref","first-page":"896","DOI":"10.1016\/S0002-8223(97)00220-4","article-title":"Continuous positive airway pressure treatment results in weight less in obese and overweight patients with obstructive sleep apnea","volume":"97","author":"Loube","year":"1997","journal-title":"J Am Diet Assoc"},{"issue":"7","key":"key\n\t\t\t\t20180328152816_CIT0045","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1161\/01.CIR.100.7.706","article-title":"Changes in intra-abdominal visceral fat and serum leptin levels in patients with obstructive sleep apnea syndrome following nasal continuous positive airway pressure therapy","volume":"100","author":"Chin","year":"1999","journal-title":"Circulation"},{"issue":"3","key":"key\n\t\t\t\t20180328152816_CIT0046","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1136\/thoraxjnl-2014-205361","article-title":"Effects of CPAP on body weight in patients with obstructive sleep apnoea: a meta-analysis of randomised trials","volume":"70","author":"Drager","year":"2015","journal-title":"Thorax"},{"issue":"10","key":"key\n\t\t\t\t20180328152816_CIT0047","doi-asserted-by":"crossref","first-page":"989","DOI":"10.5664\/jcsm.3064","article-title":"Impact of treatment with continuous positive airway pressure (CPAP) on weight in obstructive sleep apnea","volume":"9","author":"Quan","year":"2013","journal-title":"J Clin Sleep Med"},{"issue":"3","key":"key\n\t\t\t\t20180328152816_CIT0048","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1136\/thoraxjnl-2014-206484","article-title":"The complex relationship between weight and sleep apnoea","volume":"70","author":"Patel","year":"2015","journal-title":"Thorax"},{"issue":"Pt 1","key":"key\n\t\t\t\t20180328152816_CIT0049","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1113\/jphysiol.2010.197517","article-title":"Energy expenditure during sleep, sleep deprivation and sleep following sleep deprivation in adult humans","volume":"589","author":"Jung","year":"2011","journal-title":"J Physiol"},{"issue":"4","key":"key\n\t\t\t\t20180328152816_CIT0050","doi-asserted-by":"crossref","first-page":"867","DOI":"10.3945\/ajcn.113.067884","article-title":"Overnight energy expenditure determined by whole-body indirect calorimetry does not differ during different sleep stages","volume":"98","author":"Gonnissen","year":"2013","journal-title":"Am J Clin Nutr"},{"issue":"2","key":"key\n\t\t\t\t20180328152816_CIT0051","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1152\/jappl.1985.59.2.384","article-title":"Metabolic rate and breathing during sleep","volume":"59","author":"White","year":"1985","journal-title":"J Appl Physiol (1985)"},{"issue":"3","key":"key\n\t\t\t\t20180328152816_CIT0052","first-page":"201","article-title":"Oxygen consumption during sleep: influence of sleep stage and time of night","volume":"12","author":"Ryan","year":"1989","journal-title":"Sleep"},{"issue":"7","key":"key\n\t\t\t\t20180328152816_CIT0053","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1016\/j.metabol.2009.02.025","article-title":"Metabolic rate and fuel utilization during sleep assessed by whole-body indirect calorimetry","volume":"58","author":"Katayose","year":"2009","journal-title":"Metabolism"},{"issue":"6","key":"key\n\t\t\t\t20180328152816_CIT0054","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1378\/chest.115.6.1519","article-title":"Comparison of respiratory polysomnographic parameters in matched cohorts of upper airway resistance and obstructive sleep apnea syndrome patients","volume":"115","author":"Loube","year":"1999","journal-title":"Chest"},{"issue":"4","key":"key\n\t\t\t\t20180328152816_CIT0055","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1183\/09031936.03.00298903","article-title":"The role of mean inspiratory effort on daytime sleepiness","volume":"21","author":"Pelin","year":"2003","journal-title":"Eur Respir J"},{"issue":"5","key":"key\n\t\t\t\t20180328152816_CIT0056","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/S1389-9457(01)00111-3","article-title":"Variability of respiratory effort in relation to sleep stages in normal controls and upper airway resistance syndrome patients","volume":"2","author":"Guilleminault","year":"2001","journal-title":"Sleep Med"},{"issue":"6156","key":"key\n\t\t\t\t20180328152816_CIT0057","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1126\/science.1241224","article-title":"Sleep drives metabolite clearance from the adult brain","volume":"342","author":"Xie","year":"2013","journal-title":"Science"},{"issue":"3","key":"key\n\t\t\t\t20180328152816_CIT0058","first-page":"172","article-title":"Hormonal and metabolic profiles in subjects with obstructive sleep apnea syndrome and the acute effects of nasal continuous positive airway pressure (CPAP) treatment","volume":"18","author":"Cooper","year":"1995","journal-title":"Sleep"},{"issue":"4","key":"key\n\t\t\t\t20180328152816_CIT0059","doi-asserted-by":"crossref","first-page":"733","DOI":"10.5665\/sleep.3580","article-title":"Continuous positive airway pressure increases pulsatile growth hormone secretion and circulating insulin-like growth factor-1 in a time-dependent manner in men with obstructive sleep apnea: a randomized sham-controlled study","volume":"37","author":"Hoyos","year":"2014","journal-title":"Sleep"},{"issue":"5","key":"key\n\t\t\t\t20180328152816_CIT0060","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1164\/ajrccm.165.5.2103001","article-title":"Obstructive sleep apnea is independently associated with insulin resistance","volume":"165","author":"Ip","year":"2002","journal-title":"Am J Respir Crit Care Med"},{"issue":"6","key":"key\n\t\t\t\t20180328152816_CIT0061","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.5665\/sleep.3772","article-title":"Severity of obstructive sleep apnea is associated with cardiac troponin I concentrations in a community-based sample: data from the Akershus Sleep Apnea Project","volume":"37","author":"Einvik","year":"2014","journal-title":"Sleep"},{"issue":"7","key":"key\n\t\t\t\t20180328152816_CIT0062","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1111\/resp.12823","article-title":"Effects of continuous positive airway pressure on diaphragmatic kinetics and breathing pattern in healthy individuals","volume":"21","author":"Soilemezi","year":"2016","journal-title":"Respirology"}],"container-title":["Sleep"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/sleep\/article-pdf\/40\/10\/zsx128\/23836632\/zsx128.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,13]],"date-time":"2020-10-13T06:01:52Z","timestamp":1602568912000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/sleep\/article\/doi\/10.1093\/sleep\/zsx128\/4004820"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7,23]]},"references-count":62,"journal-issue":{"issue":"10","published-online":{"date-parts":[[2017,7,23]]},"published-print":{"date-parts":[[2017,10,1]]}},"URL":"https:\/\/doi.org\/10.1093\/sleep\/zsx128","relation":{},"ISSN":["0161-8105","1550-9109"],"issn-type":[{"value":"0161-8105","type":"print"},{"value":"1550-9109","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2017,10]]},"published":{"date-parts":[[2017,7,23]]}}}