{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T03:38:19Z","timestamp":1789443499626,"version":"build-2803163510"},"reference-count":41,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2018,3,7]],"date-time":"2018-03-07T00:00:00Z","timestamp":1520380800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/about_us\/legal\/notices"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,6,1]]},"DOI":"10.1093\/sleep\/zsy050","type":"journal-article","created":{"date-parts":[[2018,3,7]],"date-time":"2018-03-07T07:04:55Z","timestamp":1520406295000},"source":"Crossref","is-referenced-by-count":31,"title":["In-field assessment of sodium oxybate effect in pediatric type 1 narcolepsy: an actigraphic study"],"prefix":"10.1093","volume":"41","author":[{"given":"Marco","family":"Filardi","sequence":"first","affiliation":[{"name":"Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio","family":"Pizza","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy"},{"name":"IRCCS, Istituto delle Scienze Neurologiche, AUSL di Bologna, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Antelmi","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy"},{"name":"IRCCS, Istituto delle Scienze Neurologiche, AUSL di Bologna, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6937-3065","authenticated-orcid":false,"given":"Raffaele","family":"Ferri","sequence":"additional","affiliation":[{"name":"Department of Neurology I.C., Sleep Research Centre, Oasi Institute for Research on Mental Retardation and Brain Aging (IRCCS), Troina, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Natale","sequence":"additional","affiliation":[{"name":"Department of Psychology, University of Bologna, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Plazzi","sequence":"additional","affiliation":[{"name":"Department of Biomedical and Neuromotor Sciences (DIBINEM), University of Bologna, Bologna, Italy"},{"name":"IRCCS, Istituto delle Scienze Neurologiche, AUSL di Bologna, Bologna, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2018,3,7]]},"reference":[{"key":"key\n\t\t\t\t20180608120733_CIT0001","volume-title":"International Classification of Sleep Disorders","author":"American Academy of Sleep Medicine","year":"2014","edition":"3rd ed"},{"issue":"3","key":"key\n\t\t\t\t20180608120733_CIT0002","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/S0896-6273(00)00058-1","article-title":"Reduced number of hypocretin neurons in human narcolepsy","volume":"27","author":"Thannickal","year":"2000","journal-title":"Neuron"},{"issue":"9","key":"key\n\t\t\t\t20180608120733_CIT0003","doi-asserted-by":"crossref","first-page":"955","DOI":"10.5664\/jcsm.3004","article-title":"Disrupted nighttime sleep in narcolepsy","volume":"9","author":"Roth","year":"2013","journal-title":"J Clin Sleep Med"},{"issue":"27","key":"key\n\t\t\t\t20180608120733_CIT0004","doi-asserted-by":"crossref","first-page":"2654","DOI":"10.1056\/NEJMra1500587","article-title":"Narcolepsy","volume":"373","author":"Scammell","year":"2015","journal-title":"N Engl J Med"},{"issue":"5","key":"key\n\t\t\t\t20180608120733_CIT0005","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1016\/j.sleep.2014.01.015","article-title":"Delayed diagnosis of narcolepsy: characterization and impact","volume":"15","author":"Thorpy","year":"2014","journal-title":"Sleep Med"},{"issue":"10","key":"key\n\t\t\t\t20180608120733_CIT0006","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s11940-016-0429-y","article-title":"Management of Narcolepsy","volume":"18","author":"Barateau","year":"2016","journal-title":"Curr Treat Options Neurol"},{"issue":"2","key":"key\n\t\t\t\t20180608120733_CIT0007","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1212\/WNL.49.2.444","article-title":"Randomized, double-blind, placebo-controlled crossover trial of modafinil in the treatment of excessive daytime sleepiness in narcolepsy","volume":"49","author":"Broughton","year":"1997","journal-title":"Neurology"},{"issue":"3","key":"key\n\t\t\t\t20180608120733_CIT0008","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/S1474-4422(16)30333-7","article-title":"Safety and efficacy of pitolisant on cataplexy in patients with narcolepsy: a randomised, double-blind, placebo-controlled trial","volume":"16","author":"Szakacs","year":"2017","journal-title":"Lancet Neurol"},{"issue":"5","key":"key\n\t\t\t\t20180608120733_CIT0009","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.smrv.2011.09.001","article-title":"Narcolepsy and effectiveness of gamma-hydroxybutyrate (GHB): a systematic review and meta-analysis of randomized controlled trials","volume":"16","author":"Boscolo-Berto","year":"2012","journal-title":"Sleep Med Rev"},{"issue":"11","key":"key\n\t\t\t\t20180608120733_CIT0010","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1093\/sleep\/33.11.1457","article-title":"Clinical and therapeutic aspects of childhood narcolepsy-cataplexy: a retrospective study of 51 children","volume":"33","author":"Aran","year":"2010","journal-title":"Sleep"},{"issue":"8","key":"key\n\t\t\t\t20180608120733_CIT0011","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1093\/sleep\/29.8.1025","article-title":"Off-label treatment of severe childhood narcolepsy-cataplexy with sodium oxybate","volume":"29","author":"Murali","year":"2006","journal-title":"Sleep"},{"issue":"6","key":"key\n\t\t\t\t20180608120733_CIT0012","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.sleep.2011.10.032","article-title":"Sodium oxybate in the treatment of childhood narcolepsy-cataplexy: a retrospective study","volume":"13","author":"Mansukhani","year":"2012","journal-title":"Sleep Med"},{"key":"key\n\t\t\t\t20180608120733_CIT0013","first-page":"S339","article-title":"A double-blind, placebo-controlled, randomized-withdrawal, multicenter study on the efficacy and safety of Sodium Oxybate in pediatric subjects with Narcolepsy with Cataplexy","volume":"82","author":"Wang","year":"2017","journal-title":"Ann Neurol"},{"issue":"5","key":"key\n\t\t\t\t20180608120733_CIT0014","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1007\/s40272-014-0083-3","article-title":"Pharmacological management of narcolepsy and cataplexy in pediatric patients","volume":"16","author":"Lecendreux","year":"2014","journal-title":"Paediatr Drugs"},{"issue":"1","key":"key\n\t\t\t\t20180608120733_CIT0015","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1097\/01.wnp.0000190415.83841.17","article-title":"ACNS clinical controversy: MSLT and MWT have limited clinical utility","volume":"23","author":"Bonnet","year":"2006","journal-title":"J Clin Neurophysiol"},{"issue":"1","key":"key\n\t\t\t\t20180608120733_CIT0016","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1097\/01.wnp.0000190416.62482.42","article-title":"Objective measures of sleepiness and wakefulness: application to the real world","volume":"23","author":"Wise","year":"2006","journal-title":"J Clin Neurophysiol"},{"issue":"1","key":"key\n\t\t\t\t20180608120733_CIT0017","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.sleep.2014.08.017","article-title":"Actigraphic assessment of sleep\/wake behavior in central disorders of hypersomnolence","volume":"16","author":"Filardi","year":"2015","journal-title":"Sleep Med"},{"issue":"1","key":"key\n\t\t\t\t20180608120733_CIT0018","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.sleep.2014.07.024","article-title":"Polysomnographic and actigraphic characteristics of patients with H1N1-vaccine-related and sporadic narcolepsy","volume":"16","author":"Alakuijala","year":"2015","journal-title":"Sleep Med"},{"issue":"6","key":"key\n\t\t\t\t20180608120733_CIT0019","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.5665\/sleep.5842","article-title":"Circadian rest-activity rhythm in pediatric type 1 Narcolepsy","volume":"39","author":"Filardi","year":"2016","journal-title":"Sleep"},{"issue":"1","key":"key\n\t\t\t\t20180608120733_CIT0020","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1002\/hup.471","article-title":"Actigraphy in human psychopharmacology: a review","volume":"18","author":"Stanley","year":"2003","journal-title":"Hum Psychopharmacol"},{"issue":"2","key":"key\n\t\t\t\t20180608120733_CIT0021","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1002\/hup.666","article-title":"Diurnal actigraphy and stimulant efficacy in narcolepsy","volume":"20","author":"Bruck","year":"2005","journal-title":"Hum Psychopharmacol"},{"issue":"3","key":"key\n\t\t\t\t20180608120733_CIT0022","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1159\/000324549","article-title":"Sodium oxybate in narcolepsy with cataplexy: Zurich sleep center experience","volume":"65","author":"Poryazova","year":"2011","journal-title":"Eur Neurol"},{"issue":"1","key":"key\n\t\t\t\t20180608120733_CIT0023","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1111\/j.1365-2869.2012.01032.x","article-title":"Daytime continuous polysomnography predicts MSLT results in hypersomnias of central origin","volume":"22","author":"Pizza","year":"2013","journal-title":"J Sleep Res"},{"key":"key\n\t\t\t\t20180608120733_CIT0024","article-title":"A standardized test to document cataplexy","author":"Vandi","year":"2017","journal-title":"Sleep Med"},{"issue":"7","key":"key\n\t\t\t\t20180608120733_CIT0025","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1007\/BF03344156","article-title":"Italian cross-sectional growth charts for height, weight and BMI (2 to 20 yr)","volume":"29","author":"Cacciari","year":"2006","journal-title":"J Endocrinol Invest"},{"issue":"5","key":"key\n\t\t\t\t20180608120733_CIT0026","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1093\/ije\/30.5.1129","article-title":"Cross-national comparison of childhood obesity: the epidemic and the relationship between obesity and socioeconomic status","volume":"30","author":"Wang","year":"2001","journal-title":"Int J Epidemiol"},{"issue":"4","key":"key\n\t\t\t\t20180608120733_CIT0027","first-page":"494","article-title":"Actigraphic home-monitoring sleep-disturbed and control infants and young children: a new method for pediatric assessment of sleep-wake patterns","volume":"87","author":"Sadeh","year":"1991","journal-title":"Pediatrics"},{"key":"key\n\t\t\t\t20180608120733_CIT0028","doi-asserted-by":"crossref","first-page":"201","DOI":"10.2147\/NSS.S140143","article-title":"Assessing narcolepsy with cataplexy in children and adolescents: development of a cataplexy diary and the ESS-CHAD","volume":"9","author":"Wang","year":"2017","journal-title":"Nat Sci Sleep"},{"issue":"5","key":"key\n\t\t\t\t20180608120733_CIT0029","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.eurpsy.2015.01.006","article-title":"Measures of circadian preference in childhood and adolescence: a review","volume":"30","author":"Tonetti","year":"2015","journal-title":"Eur Psychiatry"},{"issue":"6","key":"key\n\t\t\t\t20180608120733_CIT0030","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1002\/mds.21965","article-title":"Cataplexy features in childhood narcolepsy","volume":"23","author":"Serra","year":"2008","journal-title":"Mov Disord"},{"issue":"8","key":"key\n\t\t\t\t20180608120733_CIT0031","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1016\/j.sleep.2014.03.006","article-title":"Nightmares in narcolepsy: underinvestigated symptom","volume":"15","author":"Pisko","year":"2014","journal-title":"Sleep Med"},{"issue":"6","key":"key\n\t\t\t\t20180608120733_CIT0032","doi-asserted-by":"crossref","first-page":"596","DOI":"10.5664\/jcsm.27994","article-title":"The nightly use of sodium oxybate is associated with a reduction in nocturnal sleep disruption: a double-blind, placebo-controlled study in patients with narcolepsy","volume":"6","author":"Black","year":"2010","journal-title":"J Clin Sleep Med"},{"issue":"2","key":"key\n\t\t\t\t20180608120733_CIT0033","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.sleep.2003.10.006","article-title":"A putative link between childhood narcolepsy and obesity","volume":"5","author":"Kotagal","year":"2004","journal-title":"Sleep Med"},{"issue":"7","key":"key\n\t\t\t\t20180608120733_CIT0034","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1111\/cns.12105","article-title":"Impact of obesity in children with narcolepsy","volume":"19","author":"Inocente","year":"2013","journal-title":"CNS Neurosci Ther"},{"issue":"12","key":"key\n\t\t\t\t20180608120733_CIT0035","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.5664\/jcsm.6352","article-title":"Growing up with type 1 Narcolepsy: its anthropometric and Endocrine features","volume":"12","author":"Ponziani","year":"2016","journal-title":"J Clin Sleep Med"},{"key":"key\n\t\t\t\t20180608120733_CIT0036","author":"Nardone","year":"2016"},{"issue":"4","key":"key\n\t\t\t\t20180608120733_CIT0037","doi-asserted-by":"crossref","first-page":"795","DOI":"10.5665\/sleep.3592","article-title":"Glucose and fat metabolism in narcolepsy and the effect of sodium oxybate: a hyperinsulinemic-euglycemic clamp study","volume":"37","author":"Donjacour","year":"2014","journal-title":"Sleep"},{"key":"key\n\t\t\t\t20180608120733_CIT0038","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.sleep.2017.01.014","article-title":"Validation of the epworth sleepiness scale for children and adolescents using rasch analysis","volume":"33","author":"Janssen","year":"2017","journal-title":"Sleep Med"},{"issue":"7","key":"key\n\t\t\t\t20180608120733_CIT0039","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1093\/sleep\/29.7.939","article-title":"Sodium oxybate improves excessive daytime sleepiness in narcolepsy","volume":"29","author":"Black","year":"2006","journal-title":"Sleep"},{"issue":"4","key":"key\n\t\t\t\t20180608120733_CIT0040","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1093\/sleep\/24.4.385","article-title":"A comparison of three different sleep schedules for reducing daytime sleepiness in narcolepsy","volume":"24","author":"Rogers","year":"2001","journal-title":"Sleep"},{"issue":"14","key":"key\n\t\t\t\t20180608120733_CIT0041","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1212\/WNL.0000000000003787","article-title":"Measurement of narcolepsy symptoms: the Narcolepsy severity scale","volume":"88","author":"Dauvilliers","year":"2017","journal-title":"Neurology"}],"container-title":["Sleep"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/sleep\/article-pdf\/41\/6\/zsy050\/25027104\/zsy050.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,10,29]],"date-time":"2020-10-29T01:54:30Z","timestamp":1603936470000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/sleep\/article\/doi\/10.1093\/sleep\/zsy050\/4924234"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3,7]]},"references-count":41,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2018,3,7]]},"published-print":{"date-parts":[[2018,6,1]]}},"URL":"https:\/\/doi.org\/10.1093\/sleep\/zsy050","relation":{},"ISSN":["0161-8105","1550-9109"],"issn-type":[{"value":"0161-8105","type":"print"},{"value":"1550-9109","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2018,6]]},"published":{"date-parts":[[2018,3,7]]}}}