{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T22:32:29Z","timestamp":1792794749702,"version":"4.5.0"},"reference-count":36,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,11,4]],"date-time":"2024-11-04T00:00:00Z","timestamp":1730678400000},"content-version":"vor","delay-in-days":308,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Charles Fisher is a pioneering historical figure in sleep laboratory research and sleep medicine who distinguished himself in nine areas: (1) he first documented\u00a0nocturnal sleep-onset rapid eye movement (REM) sleep periods in narcoleptic patients; (2) he published the first case of polysomnography (PSG) documented acute REM sleep behavior disorder (RBD) that was triggered by sudden withdrawal from a monoamine oxidase inhibitor in 1978, 8 years before the formal identification of RBD; (3) he worked with Roffwarg and Dement on the early delineation of the ontogeny of the human sleep cycle; (4) he first demonstrated that benzodiazepine (diazepam) therapy was effective in controlling night terrors together with suppression of stage 4 non-rapid eye movement (NREM) sleep, and he was also an early investigator of night terrors as phenomena emerging from stage 4 NREM sleep, without dreaming, as had been traditionally assumed; (5) he collaborated with another pioneering sleep medicine physician, William C. Dement on studies focused on REM sleep deprivation and dreaming at Fisher\u2019s Mt. Sinai Hospital sleep laboratory in New York City; (6) he published the first PSG-documented case of sleep-related (psychogenic) dissociative disorder in 1976; (7) he first documented that typical nightmares (\u201canxiety dreams\u201d) occurred during REM sleep; (8) he conducted some of the earliest research, beginning in 1965, that documented cycles of nocturnal penile tumescence emerging in conjunction with REM sleep cycles; and (9) he conducted similar early studies of female sexual arousal during sleep that occurred predominantly in REM sleep.<\/jats:p>","DOI":"10.1093\/sleepadvances\/zpae082","type":"journal-article","created":{"date-parts":[[2024,11,4]],"date-time":"2024-11-04T18:28:32Z","timestamp":1730744912000},"source":"Crossref","is-referenced-by-count":1,"title":["The lasting legacy of Charles Fisher (1908\u20131988), pioneering sleep laboratory scientist and sleep medicine psychiatrist"],"prefix":"10.1093","volume":"5","author":[{"given":"Carlos H","family":"Schenck","sequence":"first","affiliation":[{"name":"Minnesota Regional Sleep Disorders Center , Minneapolis, MN ,","place":["USA"]},{"name":"Department of Psychiatry, Hennepin County Medical Center , Minneapolis, MN ,","place":["USA"]},{"name":"Department of Psychiatry, University of Minnesota Medical School , Minneapolis, MN ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9063-2658","authenticated-orcid":false,"given":"Federica","family":"Provini","sequence":"additional","affiliation":[{"name":"Department of Biomedical and NeuroMotor Sciences, University of Bologna , Bologna ,","place":["Italy"]},{"name":"IRCCS Istituto delle Scienze Neurologiche di Bologna , Bologna ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan S","family":"Eiser","sequence":"additional","affiliation":[{"name":"Michigan Medicine Sleep Disorders Center , Ann Arbor, MI ,","place":["USA"]},{"name":"Department of Psychiatry, University of Michigan Medical School , Ann Arbor, MI ,","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,11,4]]},"reference":[{"key":"2024112816244668000_CIT0001","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/0013-4694(63)90032-4","article-title":"Nocturnal sleep of narcoleptics","volume":"15","author":"Rechtschaffen","year":"1963","journal-title":"Electroenceph Clin Neurophysiol."},{"key":"2024112816244668000_CIT0002","first-page":"71","article-title":"Physiological concomitants of unconscious mental processes: some clinical and therapeutic application of recent research on sleep and dreaming","volume-title":"The Unconscious: Nature, Functions, Methods of Study","author":"Fisher","year":"1978"},{"issue":"2","key":"2024112816244668000_CIT0003","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1093\/sleep\/9.2.293","article-title":"Chronic behavioral disorders of human REM sleep: a new category of parasomnia","volume":"9","author":"Schenck","year":"1986","journal-title":"Sleep."},{"key":"2024112816244668000_CIT0004","first-page":"60","article-title":"Preliminary observations of the sleep-dream pattern in neonates, infants, children, and adults","volume-title":"Problems of Sleep and Dream in Children. 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Physiological aspects of the stage 4 night terror","volume":"157","author":"Fisher","year":"1973","journal-title":"J Nerv Ment Dis."},{"issue":"3","key":"2024112816244668000_CIT0007","doi-asserted-by":"publisher","first-page":"174","DOI":"10.1097\/00005053-197403000-00002","article-title":"A psychophysiological study of nightmares and night terrors. 3. 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