{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T21:54:31Z","timestamp":1781733271023,"version":"3.54.5"},"reference-count":69,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T00:00:00Z","timestamp":1777507200000},"content-version":"vor","delay-in-days":119,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Study Objectives<\/jats:title>\n                    <jats:p>Insomnia is common in pregnancy and is associated with maladaptive sleep behaviors and poor emotion regulation. Cognitive-behavioral therapy for insomnia (CBTI) and Perinatal Understanding of Mindful Awareness for Sleep (PUMAS) are effective interventions for alleviating prenatal insomnia. However, clinical benefits outside the primary target of sleep remain unclear. This randomized controlled trial (RCT) explored the effectiveness of CBTI and PUMAS on bedtime procrastination, insomnia-focused rumination, anxiety, affect, and mindfulness.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Secondary analysis of a single-site, three-arm RCT of N\u2009=\u200964 pregnant women with clinical insomnia who were randomized to CBTI, PUMAS, or sleep hygiene education (SHE). Outcomes included the bedtime procrastination scale (BPS), daytime insomnia symptom response scale, generalized anxiety disorder-7, positive and negative affect schedule, expanded form-modified (PANAS positive and negative affect), and five facet mindfulness questionnaire (FFMQ). Patients provided treatment feedback.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>CBTI and PUMAS were associated with large reductions in BPS (Cohen\u2019s ds\u2009\u2265\u20091.02) and medium-to-large effects on PANAS positive affect (Cohen\u2019s ds\u2009\u2265\u2009.60). In a subsample of patients with anxiety symptoms, CBTI and PUMAS produced large anxiolytic effects (Cohen\u2019s ds\u2009\u2265\u2009.92). PUMAS reduced insomnia-focused rumination relative to SHE (Cohen\u2019s d\u2009=\u2009.71), whereas CBTI did not. We observed no significant effects on negative affect or FFMQ. Patients identified behavioral sleep strategies, meditation, and honoring pregnancy as particularly helpful.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>CBTI and PUMAS yield clinical gains beyond the primary target of insomnia. These findings highlight the benefits of improving sleep quality for the betterment of overall maternal wellbeing, thereby strengthening consideration of CBTI and PUMAS as first-line treatments for prenatal insomnia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Trial Registration<\/jats:title>\n                    <jats:p>Improving Negative Stressful Perseverations in Insomnia to Revitalize Expectant Moms (INSPIRE). https:\/\/clinicaltrials.gov\/study\/NCT04445805, National Library of Medicine ClinicalTrials.gov Registry: NCT04445805.<\/jats:p>\n                    <jats:p>Statement of Significance Pregnancy is a stressful period rife with significant changes in sleep patterns and behaviors. Half of women develop insomnia during pregnancy, which fuels anxiety and mood disturbances. Evidence supports Cognitive-Behavioral Therapy for Insomnia (CBTI) and Perinatal Understanding of Mindful Awareness for Sleep (PUMAS, which combines mindfulness and behavioral strategies) for alleviating prenatal insomnia. This study was a secondary analysis of a randomized controlled trial exploring whether CBTI and PUMAS yielded clinical benefits beyond sleep. Results showed that CBTI and PUMAS reduced bedtime procrastination and anxiety, and enhanced positive affect. PUMAS was associated with decreased insomnia-focused rumination, whereas CBTI was not. Trial findings build on our previously reported effectiveness results and together support CBTI and PUMAS as promising candidates for first-line prenatal insomnia treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/sleepadvances\/zpag050","type":"journal-article","created":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T13:05:31Z","timestamp":1777554331000},"source":"Crossref","is-referenced-by-count":0,"title":["Treating insomnia during pregnancy improves bedtime procrastination, rumination, anxiety, and positive affect: a randomized controlled trial of cognitive-behavioral and mindfulness-based therapies for prenatal insomnia"],"prefix":"10.1093","volume":"7","author":[{"given":"David A","family":"Kalmbach","sequence":"first","affiliation":[{"name":"Thomas Roth Sleep Disorders & Research Center , Henry Ford Health, Detroit, MI 48202 ,","place":["United States"]},{"name":"Department of Obstetrics, Gynecology, and Reproductive Biology, Michigan State University , East Lansing, MI 48824 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2783-1678","authenticated-orcid":false,"given":"Anthony N","family":"Reffi","sequence":"additional","affiliation":[{"name":"Thomas Roth Sleep Disorders & Research Center , Henry Ford Health, Detroit, MI 48202 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2874-658X","authenticated-orcid":false,"given":"Philip","family":"Cheng","sequence":"additional","affiliation":[{"name":"Thomas Roth Sleep Disorders & Research Center , Henry Ford Health, Detroit, MI 48202 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parisa R","family":"Kaliush","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, School of Medicine, University of North Carolina at Chapel Hill , Chapel Hill, NC 27599 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-3798-6022","authenticated-orcid":false,"given":"Matthew B","family":"Jennings","sequence":"additional","affiliation":[{"name":"Thomas Roth Sleep Disorders & Research Center , Henry Ford Health, Detroit, MI 48202 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heba A","family":"Afaneh","sequence":"additional","affiliation":[{"name":"Thomas Roth Sleep Disorders & Research Center , Henry Ford Health, Detroit, MI 48202 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda","family":"Yu","sequence":"additional","affiliation":[{"name":"Thomas Roth Sleep Disorders & Research Center , Henry Ford Health, Detroit, MI 48202 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Jaziri","sequence":"additional","affiliation":[{"name":"Thomas Roth Sleep Disorders & Research Center , Henry Ford Health, Detroit, MI 48202 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5486-3587","authenticated-orcid":false,"given":"Christopher L","family":"Drake","sequence":"additional","affiliation":[{"name":"Thomas Roth Sleep Disorders & Research Center , Henry Ford Health, Detroit, MI 48202 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,4,30]]},"reference":[{"issue":"1","key":"2026061717302666100_ref1","doi-asserted-by":"publisher","first-page":"e13207","DOI":"10.1111\/jsr.13207","article-title":"Insomnia symptoms during pregnancy: a meta-analysis","volume":"30","author":"Sedov","year":"2021","journal-title":"J Sleep Res"},{"issue":"4","key":"2026061717302666100_ref2","doi-asserted-by":"publisher","first-page":"e94674","DOI":"10.1371\/journal.pone.0094674","article-title":"Can insomnia in pregnancy predict postpartum depression? 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