{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T19:16:34Z","timestamp":1791400594421,"version":"4.3.3"},"reference-count":70,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes of Health Research Foundation","doi-asserted-by":"crossref","award":["FDN-143316"],"award-info":[{"award-number":["FDN-143316"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Ontario Institute of Regenerative Medicine"},{"DOI":"10.13039\/501100000098","name":"Canadian Stem Cell Network","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000098","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Children\u2019s Hospital of Eastern Ontario Foundation"},{"name":"Gesellschaft f\u00fcr Neonatologie und P\u00e4diatrische Intensivmedizin"},{"DOI":"10.13039\/501100002957","name":"Technische Universit\u00e4t Dresden","doi-asserted-by":"publisher","award":["60464"],"award-info":[{"award-number":["60464"]}],"id":[{"id":"10.13039\/501100002957","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004350","name":"Studienstiftung des deutschen Volkes","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004350","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100006360","name":"Bundesministerium f\u00fcr Wirtschaft und Energie","doi-asserted-by":"publisher","award":["03EFJSN115"],"award-info":[{"award-number":["03EFJSN115"]}],"id":[{"id":"10.13039\/501100006360","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002428","name":"Austrian Science Fund","doi-asserted-by":"publisher","award":["P19398"],"award-info":[{"award-number":["P19398"]}],"id":[{"id":"10.13039\/501100002428","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Southwest National Primate Research Center","award":["P51 OD011133"],"award-info":[{"award-number":["P51 OD011133"]}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,3,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>Premature birth is a leading cause of childhood morbidity and mortality and often followed by an arrest of postnatal lung development called bronchopulmonary dysplasia. Therapies using exogenous mesenchymal stromal cells (MSC) have proven highly efficacious in term-born rodent models of this disease, but effects of MSC in actual premature-born lungs are largely unknown. Here, we investigated thirteen non-human primates (baboons; Papio spp.) that were born at the limit of viability and given a single, intravenous dose of ten million human umbilical cord tissue-derived MSC per kilogram or placebo immediately after birth. Following two weeks of human-equivalent neonatal intensive care including mechanical ventilation, lung function testing and echocardiographic studies, lung tissues were analyzed using unbiased stereology. We noted that therapy with MSC was feasible, safe and without signs of engraftment when administered as controlled infusion over 15 minutes, but linked to adverse events when given faster. Administration of cells was associated with improved cardiovascular stability, but neither benefited lung structure, nor lung function after two weeks of extrauterine life. We concluded that a single, intravenous administration of MSC had no short- to mid-term lung-protective effects in extremely premature-born baboons, sharply contrasting data from term-born rodent models of arrested postnatal lung development and urging for investigations on the mechanisms of cell-based therapies for diseases of prematurity in actual premature organisms.<\/jats:p>","DOI":"10.1093\/stcltm\/szac088","type":"journal-article","created":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T00:38:17Z","timestamp":1675298297000},"page":"97-111","source":"Crossref","is-referenced-by-count":16,"title":["Prophylactic Administration of Mesenchymal Stromal Cells Does Not Prevent Arrested Lung Development in Extremely Premature-Born Non-Human Primates"],"prefix":"10.1093","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8811-8454","authenticated-orcid":false,"given":"Marius A","family":"M\u00f6bius","sequence":"first","affiliation":[{"name":"Neonatology and Pediatric Critical Care Medicine, Department of Pediatrics, University Hospital Carl Gustav Carus, Technische Universit\u00e4t Dresden , Dresden, Saxony , Germany"},{"name":"Saxonian Center for Feto\/ Neonatal Health, Medical Faculty Carl Gustav Carus, Technische Universit\u00e4t Dresden , Dresden, Saxony , Germany"},{"name":"Good Manufacturing Practice, Center for Regenerative Therapies, Technische Universit\u00e4t Dresden , Dresden, Saxony , Germany"},{"name":"Neonatology, Department of Pediatrics, University of Texas Health Science Center at San Antonio , San Antonio, TX , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4205-108X","authenticated-orcid":false,"given":"Steven R","family":"Seidner","sequence":"additional","affiliation":[{"name":"Neonatology, Department of Pediatrics, University of Texas Health Science Center at San Antonio , San Antonio, TX , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald C","family":"McCurnin","sequence":"additional","affiliation":[{"name":"Neonatology, Department of Pediatrics, University of Texas Health Science Center at San Antonio , San Antonio, TX , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1508-5679","authenticated-orcid":false,"given":"Leonhard","family":"Menschner","sequence":"additional","affiliation":[{"name":"Neonatology and Pediatric Critical Care Medicine, Department of Pediatrics, University Hospital Carl Gustav Carus, Technische Universit\u00e4t Dresden , Dresden, Saxony , Germany"},{"name":"Saxonian Center for Feto\/ Neonatal Health, Medical Faculty Carl Gustav Carus, Technische Universit\u00e4t Dresden , Dresden, Saxony , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabel","family":"F\u00fcrb\u00f6ter-Behnert","sequence":"additional","affiliation":[{"name":"Neonatology and Pediatric Critical Care Medicine, Department of Pediatrics, University Hospital Carl Gustav Carus, Technische Universit\u00e4t Dresden , Dresden, Saxony , Germany"},{"name":"Saxonian Center for Feto\/ Neonatal Health, Medical Faculty Carl Gustav Carus, Technische Universit\u00e4t Dresden , Dresden, Saxony , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1621-0833","authenticated-orcid":false,"given":"Julia","family":"Sch\u00f6nfeld","sequence":"additional","affiliation":[{"name":"Neonatology and Pediatric Critical Care Medicine, Department of Pediatrics, University Hospital Carl Gustav Carus, Technische Universit\u00e4t Dresden , Dresden, Saxony , Germany"},{"name":"Saxonian Center for Feto\/ Neonatal Health, Medical Faculty Carl Gustav Carus, Technische Universit\u00e4t Dresden , Dresden, Saxony , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jenny","family":"Marzahn","sequence":"additional","affiliation":[{"name":"Neonatology and Pediatric Critical Care Medicine, Department of Pediatrics, University Hospital Carl Gustav Carus, Technische Universit\u00e4t Dresden , Dresden, Saxony , Germany"},{"name":"Saxonian Center for Feto\/ Neonatal Health, Medical Faculty Carl Gustav Carus, Technische Universit\u00e4t Dresden , Dresden, Saxony , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4619-7246","authenticated-orcid":false,"given":"Daniel","family":"Freund","sequence":"additional","affiliation":[{"name":"Neonatology and Pediatric Critical Care Medicine, Department of Pediatrics, University Hospital Carl Gustav Carus, Technische Universit\u00e4t Dresden , Dresden, Saxony , Germany"},{"name":"Good Manufacturing Practice, Center for Regenerative Therapies, Technische Universit\u00e4t Dresden , Dresden, Saxony , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadine","family":"M\u00fcnch","sequence":"additional","affiliation":[{"name":"Neonatology and Pediatric Critical Care Medicine, Department of Pediatrics, University Hospital Carl Gustav Carus, Technische Universit\u00e4t Dresden , Dresden, Saxony , Germany"},{"name":"Good Manufacturing Practice, Center for Regenerative Therapies, Technische Universit\u00e4t Dresden , Dresden, Saxony , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"Hering","sequence":"additional","affiliation":[{"name":"Forensic Genetics, Institute for Legal Medicine, Medical Faculty Carl Gustav Carus, Technische Universit\u00e4t Dresden , Dresden, Saxony , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shamimunisa B","family":"Mustafa","sequence":"additional","affiliation":[{"name":"Neonatology, Department of Pediatrics, University of Texas Health Science Center at San Antonio , San Antonio, TX , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diana G","family":"Anzueto","sequence":"additional","affiliation":[{"name":"Neonatology, Department of Pediatrics, University of Texas Health Science Center at San Antonio , San Antonio, TX , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauryn A","family":"Winter","sequence":"additional","affiliation":[{"name":"Neonatology, Department of Pediatrics, University of Texas Health Science Center at San Antonio , San Antonio, TX , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia L","family":"Blanco","sequence":"additional","affiliation":[{"name":"Neonatology, Department of Pediatrics, University of Texas Health Science Center at San Antonio , San Antonio, TX , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martha A","family":"Hanes","sequence":"additional","affiliation":[{"name":"Pathology Services, Laboratory Animal Resources, University of Texas Health Science Center at San Antonio , San Antonio, TX , USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7498-1209","authenticated-orcid":false,"given":"Mario","family":"R\u00fcdiger","sequence":"additional","affiliation":[{"name":"Neonatology and Pediatric Critical Care Medicine, Department of Pediatrics, University Hospital Carl Gustav Carus, Technische Universit\u00e4t Dresden , Dresden, Saxony , Germany"},{"name":"Saxonian Center for Feto\/ Neonatal Health, Medical Faculty Carl Gustav Carus, Technische Universit\u00e4t Dresden , Dresden, Saxony , Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1844-7145","authenticated-orcid":false,"given":"Bernard","family":"Th\u00e9baud","sequence":"additional","affiliation":[{"name":"Regenerative Medicine Program, Ottawa Hospital Research Institute , Ottawa, ON , Canada"},{"name":"Neonatology, Department of Pediatrics, Children\u2019s Hospital of Eastern Ontario (CHEO) and CHEO Research Institute , Ottawa, ON , Canada"},{"name":"Department of Cellular and Molecular Medicine, University of Ottawa , Ottawa, ON , Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,2,1]]},"reference":[{"issue":"263","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"263ed21","DOI":"10.1126\/scitranslmed.aaa2563","article-title":"Preterm birth: now the leading cause of child death worldwide.","volume":"6","author":"Lawn","year":"2014","journal-title":"Sci Transl Med"},{"issue":"1","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1038\/s41572-019-0127-7","article-title":"Bronchopulmonary dysplasia.","volume":"5","author":"Th\u00e9baud","year":"2019","journal-title":"Nat Rev Dis Primers"},{"issue":"6","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"L832","DOI":"10.1152\/ajplung.00369.2019","article-title":"Recent advances in our understanding of 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Pediatr"},{"issue":"10","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"1708","DOI":"10.1016\/j.stem.2021.09.006","article-title":"Mesenchymal stromal cells: putative microenvironmental modulators become cell therapy.","volume":"28","author":"Krampera","year":"2021","journal-title":"Cell Stem Cell"},{"key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1038\/s41536-019-0083-6","article-title":"Mesenchymal stem cell perspective: cell biology to clinical progress.","volume":"4","author":"Pittenger","year":"2019","journal-title":"NPJ Regen Med"},{"issue":"10","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.1016\/j.stem.2021.09.001","article-title":"Multipotent stromal cells: one name, multiple identities.","volume":"28","author":"Soliman","year":"2021","journal-title":"Cell Stem 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approval.","volume":"11","author":"Kirkham","year":"2022","journal-title":"Stem Cells Transl Med"},{"issue":"2","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1002\/sctm.19-0193","article-title":"Are all stem cells equal? Systematic review, evidence map, and meta-analyses of preclinical stem cell-based therapies for bronchopulmonary dysplasia.","volume":"9","author":"Augustine","year":"2020","journal-title":"Stem Cells Transl Med"},{"issue":"12","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1002\/sctm.17-0126","article-title":"Mesenchymal stromal cell therapy in bronchopulmonary dysplasia: systematic review and meta-analysis of preclinical studies.","volume":"6","author":"Augustine","year":"2017","journal-title":"Stem Cells Transl Med"},{"issue":"3","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1038\/s41390-020-0758-0","article-title":"How to introduce MSC-based therapy for the developing lung safely into clinical care?","volume":"88","author":"R\u00fcdiger","year":"2020","journal-title":"Pediatr Res"},{"issue":"14","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1089\/scd.2016.0329","article-title":"Human umbilical cord mesenchymal stromal cells improve survival and bacterial clearance in neonatal sepsis in rats.","volume":"26","author":"Zhu","year":"2017","journal-title":"Stem Cells Dev"},{"issue":"1","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1186\/s13287-018-0802-8","article-title":"Strategies to improve the therapeutic effects of mesenchymal stromal cells in respiratory diseases.","volume":"9","author":"Silva","year":"2018","journal-title":"Stem Cell Res Ther"},{"issue":"3","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1038\/bmt.2008.316","article-title":"Treatment of refractory acute GVHD with third-party MSC expanded in platelet lysate-containing medium.","volume":"43","author":"von Bonin","year":"2009","journal-title":"Bone Marrow Transplant"},{"issue":"4","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1080\/14653240600855905","article-title":"Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement.","volume":"8","author":"Dominici","year":"2006","journal-title":"Cytotherapy"},{"issue":"5","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1165\/rcmb.2018-0358OC","article-title":"Oxygen disrupts human fetal lung mesenchymal cells. implications for bronchopulmonary dysplasia.","volume":"60","author":"M\u00f6bius","year":"2019","journal-title":"Am J Respir Cell Mol Biol"},{"issue":"1","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1038\/mt.2011.189","article-title":"Human MSC suppression correlates with cytokine induction of indoleamine 2,3-dioxygenase and bystander M2 macrophage differentiation.","volume":"20","author":"Fran\u00e7ois","year":"2012","journal-title":"Mol Ther"},{"issue":"9","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1093\/hmg\/ddy439","article-title":"Impact of Fgf10 deficiency on pulmonary vasculature formation in a mouse model of bronchopulmonary dysplasia.","volume":"28","author":"Chao","year":"2019","journal-title":"Hum Mol Genet"},{"issue":"3","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1038\/mt.2014.217","article-title":"Mesenchymal stem cells correct inappropriate epithelial-mesenchyme relation in pulmonary fibrosis using stanniocalcin-1.","volume":"23","author":"Ono","year":"2015","journal-title":"Mol Ther"},{"key":"2023040206001749100_","article-title":"Morphometric methods.","volume-title":"The Lung - Scientific Foundations","author":"Weibel","year":"1997","edition":"2"},{"key":"2023040206001749100_","first-page":"CD011932","article-title":"Mesenchymal stem cells for the prevention and treatment of bronchopulmonary dysplasia in preterm infants.","volume":"11","author":"Pierro","year":"2017","journal-title":"Cochrane Database Syst Rev"},{"issue":"6","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"1982","DOI":"10.1164\/ajrccm.158.6.9804128","article-title":"Abnormal surfactant metabolism and function in preterm ventilated baboons.","volume":"158","author":"Seidner","year":"1998","journal-title":"Am J Respir Crit Care Med"},{"issue":"12","key":"2023040206001749100_","article-title":"Antenatal corticosteroids for accelerating fetal lung maturation for women at risk of preterm birth.","author":"McGoldrick","year":"2020","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"3","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"L450","DOI":"10.1152\/ajplung.00347.2004","article-title":"Inhaled NO improves early pulmonary function and modifies lung growth and elastin deposition in a baboon model of neonatal chronic lung disease.","volume":"288","author":"McCurnin","year":"2005","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"issue":"4","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1148\/rg.254055019","article-title":"From the archives of the AFIP: lung disease in premature neonates: radiologic-pathologic correlation.","volume":"25","author":"Agrons","year":"2005","journal-title":"Radiographics"},{"issue":"01","key":"2023040206001749100_","doi-asserted-by":"crossref","DOI":"10.4172\/2167-0897.S1-e001","article-title":"Respiratory distress syndrome in full-term neonates.","volume":"S1","author":"Liu","year":"2012","journal-title":"J Neonatal Biol"},{"issue":"4","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1164\/rccm.200809-1522ST","article-title":"An official research policy statement of the American Thoracic Society\/European Respiratory Society: standards for quantitative assessment of lung structure.","volume":"181","author":"Hsia","year":"2010","journal-title":"Am J Respir Crit Care Med"},{"issue":"1","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"L15","DOI":"10.1152\/ajplung.00429.2012","article-title":"Quantitative microscopy of the lung: a problem-based approach. Part 1: basic principles of lung stereology.","volume":"305","author":"Ochs","year":"2013","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"issue":"3","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"L205","DOI":"10.1152\/ajplung.00427.2012","article-title":"Quantitative microscopy of the lung: a problem-based approach. Part 2: stereological parameters and study designs in various diseases of the respiratory tract.","volume":"305","author":"M\u00fchlfeld","year":"2013","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"issue":"1","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.aanat.2013.04.011","article-title":"Design-based stereology: planning, volumetry and sampling are crucial steps for a successful study.","volume":"196","author":"Tschanz","year":"2014","journal-title":"Ann Anat"},{"issue":"1","key":"2023040206001749100_","first-page":"57","article-title":"A simple method for volumetry of organs in quantitative stereology.","volume":"26","author":"Scherle","year":"1970","journal-title":"Mikroskopie"},{"issue":"4","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"L341","DOI":"10.1152\/ajplung.00329.2013","article-title":"Alterations of mouse lung tissue dimensions during processing for morphometry: a comparison of methods.","volume":"306","author":"Schneider","year":"2014","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"issue":"1985","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1152\/japplphysiol.00808.2006","article-title":"How much is there really? Why stereology is essential in lung morphometry.","volume":"102","author":"Weibel","year":"2007","journal-title":"J Appl Physiol"},{"key":"2023040206001749100_","volume-title":"Unbiased Stereology. 20th Anniversary Edition","author":"Howard","year":"2018"},{"issue":"4","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"595","DOI":"10.2307\/2556113","article-title":"Best linear unbiased estimators for stereology.","volume":"36","author":"Cruz-Orive","year":"1980","journal-title":"Biometrics"},{"key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/bs.mcb.2017.08.008","article-title":"Measurement of elastin, collagen, and total protein levels in tissues.","volume":"143","author":"Stoilov","year":"2018","journal-title":"Methods Cell Biol"},{"key":"2023040206001749100_","volume-title":"R: a language and environment for statistical computing","author":"R Core Team.","year":"2018"},{"issue":"4","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1164\/ajrccm.160.4.9810071","article-title":"Neonatal chronic lung disease in extremely immature baboons.","volume":"160","author":"Coalson","year":"1999","journal-title":"Am J Respir Crit Care Med"},{"issue":"8","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1164\/rccm.201803-0428OC","article-title":"Early Pulmonary Vascular Disease in Preterm Infants Is Associated with Late Respiratory Outcomes in Childhood.","volume":"199","author":"Mourani","year":"2019","journal-title":"Am J Respir Crit Care Med"},{"issue":"11","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1164\/rccm.201907-1342OC","article-title":"Characterization of disease phenotype in very preterm infants with severe bronchopulmonary dysplasia.","volume":"201","author":"Wu","year":"2020","journal-title":"Am J Respir Crit Care Med"},{"issue":"6","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1089\/scd.2019.0116","article-title":"Late rescue therapy with cord-derived mesenchymal stromal cells for established lung injury in experimental bronchopulmonary dysplasia.","volume":"29","author":"O\u2019Reilly","year":"2020","journal-title":"Stem Cells Dev"},{"issue":"12","key":"2023040206001749100_","doi-asserted-by":"crossref","first-page":"L948","DOI":"10.1152\/ajplung.00160.2014","article-title":"Animal models of bronchopulmonary dysplasia. 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