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We explore developments in anti-bacterial compounds to counteract Yersinia infections, focusing on both traditional antibiotic therapies and novel strategies targeting virulence factors, host-pathogen interactions, and vaccine development. This review evaluates current strategies for the treatment and management of Yersinia infections, outlining key challenges and emerging opportunities for improved clinical outcomes.<\/jats:p>","DOI":"10.1093\/sumbio\/qvag014","type":"journal-article","created":{"date-parts":[[2026,4,11]],"date-time":"2026-04-11T11:43:19Z","timestamp":1775907799000},"source":"Crossref","is-referenced-by-count":1,"title":["Anti-infective compounds for\n                    <i>Yersinia<\/i>"],"prefix":"10.1093","volume":"3","author":[{"given":"Kumar D","family":"Gahlot","sequence":"first","affiliation":[{"name":"Ume\u00e5 University Department of Molecular Biology, and Ume\u00e5 Centre for Microbial Research, , SE-90187 Ume\u00e5 ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6817-9535","authenticated-orcid":false,"given":"Matthew S","family":"Francis","sequence":"additional","affiliation":[{"name":"Ume\u00e5 University Department of Molecular Biology, and Ume\u00e5 Centre for Microbial Research, , SE-90187 Ume\u00e5 ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jyoti M","family":"Gurung","sequence":"additional","affiliation":[{"name":"Ume\u00e5 University Department of Molecular Biology, and Ume\u00e5 Centre for Microbial Research, , SE-90187 Ume\u00e5 ,","place":["Sweden"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,4,11]]},"reference":[{"key":"2026042910325726000_bib1","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1111\/j.1365-2761.2009.01086.x","article-title":"Cellular components of probiotics control Yersinia ruckeri infection in rainbow trout, oncorhynchus mykiss (Walbaum)","volume":"33","author":"Abbass","year":"2010","journal-title":"J Fish Dis"},{"key":"2026042910325726000_bib2","doi-asserted-by":"publisher","first-page":"2396","DOI":"10.1128\/IAI.03056-14","article-title":"the Cpx system regulates virulence gene expression in Vibrio cholerae","volume":"83","author":"Acosta","year":"2015","journal-title":"Infect Immun"},{"key":"2026042910325726000_bib3","doi-asserted-by":"crossref","first-page":"5575","DOI":"10.1099\/ijsem.0.001485","article-title":"Genome-based phylogeny and taxonomy of the \u2018Enterobacteriales\u2019: proposal for Enterobacterales ord. nov. 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