{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T12:45:01Z","timestamp":1790858701017,"version":"4.1.0"},"reference-count":38,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T00:00:00Z","timestamp":1786924800000},"content-version":"vor","delay-in-days":228,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,7,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Global soil degradation and increasing reliance on chemical inputs threaten agricultural sustainability, driving interest in microbial inoculants as tools for soil restoration. These biological products have the potential to enhance nutrient cycling, improve soil structure, and support plant resilience, but their environmental release raises important safety and stewardship considerations. Here, we propose a risk-proportional framework for the responsible deployment of microbial inoculants grounded in release-based stewardship. The framework integrates genome-resolved strain identification, exclusionary hazard screening, bioassay-based risk triage, ecological testing under realistic conditions, and monitored field deployment. Drawing on evidence from microbial ecology and invasion biology, we highlight how inoculants can alter resident microbial communities, influence ecosystem function, and, in some cases, facilitate gene flow, underscoring the need for risk assessment. We further outline a federated, genome-informed data infrastructure to support traceability, cross-jurisdiction learning, and adaptive management. Together, this approach provides a scalable and scientifically grounded pathway to balance innovation and safety, enabling microbial technologies to contribute to soil restoration and climate-resilient agriculture.<\/jats:p>","DOI":"10.1093\/sumbio\/qvag036","type":"journal-article","created":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T11:15:45Z","timestamp":1786965345000},"source":"Crossref","is-referenced-by-count":2,"title":["Microbial inoculants for soil restoration: a risk-proportional stewardship framework integrating strain-resolved genomics and adaptive governance"],"prefix":"10.1093","volume":"3","author":[{"given":"Anna","family":"Edlund","sequence":"first","affiliation":[{"name":"The Soil Stars, Applied Microbiology International , Cambridge CB12LA ,","place":["United Kingdom"]},{"name":"Oath Inc. , San Francisco, CA 94129 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gwyn A","family":"Beattie","sequence":"additional","affiliation":[{"name":"The Soil Stars, Applied Microbiology International , Cambridge CB12LA ,","place":["United Kingdom"]},{"name":"Department of Plant Pathology, Entomology and Microbiology, Iowa State University , Ames, IA 50011 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joana Falcao","family":"Salles","sequence":"additional","affiliation":[{"name":"The Soil Stars, Applied Microbiology International , Cambridge CB12LA ,","place":["United Kingdom"]},{"name":"Microbial Ecology Cluster, Genomics Research in Ecology and Evolution in Nature (GREEN), Groningen Institute for Evolutionary Life Sciences (GELIFES), University of Groningen , Groningen 9747AG ,","place":["The Netherlands"]},{"name":"The Netherlands & Department of Microbial Ecology, Centre for Life Sciences, University of Groningen , 9700 Groningen ,","place":["The Netherlands"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7920-7001","authenticated-orcid":false,"given":"Jack A","family":"Gilbert","sequence":"additional","affiliation":[{"name":"The Soil Stars, Applied Microbiology International , Cambridge CB12LA ,","place":["United Kingdom"]},{"name":"Oath Inc. , San Francisco, CA 94129 ,","place":["United States"]},{"name":"Department of Pediatrics, University of California San Diego , La Jolla, CA 92037 ,","place":["United States"]},{"name":"The UC San Diego Soil Health Center, Scripps Institution of Oceanography, University of California San Diego , La Jolla, CA 92037 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janet K","family":"Jansson","sequence":"additional","affiliation":[{"name":"The Soil Stars, Applied Microbiology International , Cambridge CB12LA ,","place":["United Kingdom"]},{"name":"Oath Inc. , San Francisco, CA 94129 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jay T","family":"Lennon","sequence":"additional","affiliation":[{"name":"The Soil Stars, Applied Microbiology International , Cambridge CB12LA ,","place":["United Kingdom"]},{"name":"Department of Biology, Indiana University , Bloomington, IN 47405 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer B H","family":"Martiny","sequence":"additional","affiliation":[{"name":"The Soil Stars, Applied Microbiology International , Cambridge CB12LA ,","place":["United Kingdom"]},{"name":"Department of Ecology & Evolutionary Biology, University of California , Irvine, CA 92697 ,","place":["United States"]},{"name":"Department of Biotechnology and Biomedicine, Technical University of Denmark , Kongens Lyngby DK-2800 ,","place":["Denmark"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian R","family":"Sanders","sequence":"additional","affiliation":[{"name":"The Soil Stars, Applied Microbiology International , Cambridge CB12LA ,","place":["United Kingdom"]},{"name":"Department of Ecology and Evolution, University of Lausanne , Lausanne CH-1015 ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher W","family":"Schadt","sequence":"additional","affiliation":[{"name":"The Soil Stars, Applied Microbiology International , Cambridge CB12LA ,","place":["United Kingdom"]},{"name":"Biosciences Division, Oak Ridge National Laboratory , Oak Ridge, TN 37831 ,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carsten Suhr","family":"Jacobsen","sequence":"additional","affiliation":[{"name":"The Soil Stars, Applied Microbiology International , Cambridge CB12LA ,","place":["United Kingdom"]},{"name":"Department of Environmental Science, Aarhus University , Roskilde DK-4000 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