{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T01:22:40Z","timestamp":1780622560105,"version":"3.54.1"},"reference-count":35,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2024,1,11]],"date-time":"2024-01-11T00:00:00Z","timestamp":1704931200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3,26]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>Solid organ transplant (SOT) has an anticipated higher risk of penile prosthesis (PP) complications related to immunosuppression and surgical approach post-SOT. It is still not determined if PP surgery in the SOT population incurs these same higher risks.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Objectives<\/jats:title>\n                  <jats:p>To observe differences in intra- and postoperative PP complications between SOT and non-SOT cases from the TriNetX US Collaborative Network, a large real-world database of deidentified patient data from 56 health care organizations within the United States.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>We used the TriNetX database to perform a propensity score\u2013matched cohort study comparing 10-year outcomes between patients with and without a SOT (kidney, heart, lung, liver, pancreas, and intestine) who underwent a PP procedure. Cohorts were matched on age, race\/ethnicity, history of pelvic and abdominal surgery, overweight and obesity status, type 2 diabetes mellitus, atherosclerosis, substance use disorders, socioeconomic difficulties, anticoagulant\/antiplatelet medications, and spinal cord injury. Outcomes included intra- and perioperative complications as well as prosthetic complications (mechanical malfunction, fibrosis, displacement, hemorrhage, pain, stenosis, removal with or without replacement, and complex [all postoperative complications]).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>There were 233 patients in each group after matching (SOT and non-SOT). The mean \u00b1 SD age at the prosthesis procedure was 59.7\u2009\u00b1\u20099.89 years, and 44% of patients were White (P\u2009&amp;gt;\u2009.05). There was no significant difference for incidence of intra- and perioperative complications (2.62% vs 2.19%, P\u2009=\u2009.76). The SOT group did not have a higher 10-year incidence of complex complications (30.58% vs 27.51%, P\u2009=\u2009.11) or mechanical malfunction (10.35% vs 11.62%, P\u2009=\u2009.25) when compared with the non-SOT group. No difference was found for other prosthetic-related complications (P\u2009&amp;gt;\u2009.05).<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusion<\/jats:title>\n                  <jats:p>In our analysis, patients with a SOT were not more likely to experience long-term complications related to PP. Surgeons performing PP surgery in the SOT population may consider this procedure a potentially safe and viable option for restoring erectile function.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/sxmrev\/qead057","type":"journal-article","created":{"date-parts":[[2024,1,13]],"date-time":"2024-01-13T00:56:52Z","timestamp":1705107412000},"page":"240-248","source":"Crossref","is-referenced-by-count":2,"title":["A propensity score\u2013matched analysis of intra- and postoperative penile prosthetic complications in the solid organ transplant population"],"prefix":"10.1093","volume":"12","author":[{"given":"John C","family":"Johnson","sequence":"first","affiliation":[{"name":"John Sealy School of Medicine, University of Texas Medical Branch , Galveston, TX 77555 , United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahul","family":"Venna","sequence":"additional","affiliation":[{"name":"John Sealy School of Medicine, University of Texas Medical Branch , Galveston, TX 77555 , United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laith","family":"Alzweri","sequence":"additional","affiliation":[{"name":"Division of Urology , Department of Surgery, , Galveston, TX 77555 , United States"},{"name":"University of Texas Medical Branch , Department of Surgery, , Galveston, TX 77555 , United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,1,11]]},"reference":[{"issue":"1","key":"2024040211595911600_ref1","doi-asserted-by":"crossref","first-page":"16003","DOI":"10.1038\/nrdp.2016.3","article-title":"Erectile dysfunction","volume":"2","author":"Yafi","year":"2016","journal-title":"Nat Rev Dis Primers"},{"issue":"2","key":"2024040211595911600_ref2","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/j.sxmr.2019.10.002","article-title":"The prevalence and treatment of erectile dysfunction in male solid organ transplant 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