{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T23:00:51Z","timestamp":1791241251366,"version":"4.1.0"},"reference-count":155,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T00:00:00Z","timestamp":1755734400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,10,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The intersection of culture, history, religion, traditions, laws, political trends, and evolving attitudes affects sexual expression and acceptance or rejection of sexual practices. Clinicians and clinical care are affected by these factors as well, although clinicians are not always aware of the way in which their training, their own experiences and attitudes influence the way in which they approach patients. In this paper, we contextualize and then describe 2 areas of sexual practices and 1 area of sexual difficulty that sexual medicine clinicians encounter in their practice, namely, the practice of female genital mutilation\/cutting, penile circumcision, and the experience of unconsummated marriages.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Given the emerging knowledge of the socio-cultural aspects of sexual medicine, we conducted a narrative review of the extant literature through wide searches in PubMed, Google, and on global websites relevant to this topic, such as the World Health Organization, the United Nations, and others. The content of this paper was reviewed by all the authors, discussed where disagreements occurred, or additional perspectives were needed, and further literature was incorporated.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We describe known practices of female genital cutting\/mutilation and penile circumcision, their perceived benefits, and harms, but also with a view to the importance of patient empowerment and respect for self-determination. We discuss unconsummated marriages as the result of often culturally determined insufficient sex education and guidance, as well as clinical resources.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>We recommend that clinicians approach patients with both curiosity and cultural humility and that the International Society for Sexual Medicine (ISSM) adopt a strong ethical perspective as a part of the ongoing discourse on these practices and experiences.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/sxmrev\/qeaf050","type":"journal-article","created":{"date-parts":[[2025,7,28]],"date-time":"2025-07-28T11:25:27Z","timestamp":1753701927000},"page":"574-588","source":"Crossref","is-referenced-by-count":4,"title":["The socio-cultural aspects of sexual medicine: recommendations from the Fifth International Consultation on Sexual Medicine (ICSM 2024)"],"prefix":"10.1093","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9201-7269","authenticated-orcid":false,"given":"Daniela","family":"Wittmann","sequence":"first","affiliation":[{"name":"University of Michigan , Department of Urology, Ann Arbor, MI 48109,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kunjappan","family":"Promodu","sequence":"additional","affiliation":[{"name":"Dr. Promodu\u2019s Institute of Sexual Medicine and Marital Health, Department of Sexual Medicine , 682024 Kerala ,","place":["India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joachim","family":"Osur","sequence":"additional","affiliation":[{"name":"Amref International University , Vice Chancelor, Nairobi 00625,","place":["Kenya"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasmine","family":"Abdulcadir","sequence":"additional","affiliation":[{"name":"University of Geneva, Department of Pediatrics, Obstetrics and Gynecology , Geneva ,","place":["Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Crista","family":"Johnson-Agbakwu","sequence":"additional","affiliation":[{"name":"University of Massachusetts T.H. Chan Medical School , Worcester, MA 01655,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalie","family":"Sorial","sequence":"additional","affiliation":[{"name":"University of Massachusetts T.H. Chan Medical School , Worcester, MA 01655,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hussein","family":"Ghanem","sequence":"additional","affiliation":[{"name":"Cairo University Hospitals, Department of Andrology, Sexology and STDs , Faculty of Medicine, Cairo 11555,","place":["Egypt"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ira","family":"Sharlip","sequence":"additional","affiliation":[{"name":"University of California-San Francisco, Department of Urology , San Francisco, CA 94143,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pedro Caetano","family":"Edler Zandon\u00e1","sequence":"additional","affiliation":[{"name":"Andrology Research Group , Hospital das Cl\u00ednicas Faculdade de Medicina, Universidade de Sa\u00f5 Paolo, Sa\u00f5 Paolo SP, 05003-000,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy","family":"Pearlman","sequence":"additional","affiliation":[{"name":"Prime Institute , Coral Gables, FL 33143,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong-Chiang","family":"Chang","sequence":"additional","affiliation":[{"name":"National Taiwan University , Xinyi District, Taipei 110024,","place":["Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sidney","family":"Glina","sequence":"additional","affiliation":[{"name":"Centro Universit\u00e1rio FMABC , Division of Urology, Sa\u00f5 Paolo ,","place":["Brazil"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,8,21]]},"reference":[{"key":"2026020606514105500_ref1","volume-title":"Crossing the Quality Chasm","author":"Danforth WH, Perrin EB. 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