{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T09:03:26Z","timestamp":1776762206197,"version":"3.51.2"},"reference-count":368,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2026,2,23]],"date-time":"2026-02-23T00:00:00Z","timestamp":1771804800000},"content-version":"vor","delay-in-days":53,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["DP5OD031876"],"award-info":[{"award-number":["DP5OD031876"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["L30CA274758"],"award-info":[{"award-number":["L30CA274758"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","award":["2217513-001"],"award-info":[{"award-number":["2217513-001"]}],"id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,1,2]]},"abstract":"Abstract<\/jats:title>\n \n Introduction<\/jats:title>\n Disorders of chronic illness and certain cancers are common and can pose a substantial burden to the individual and their sexual partners.<\/jats:p>\n <\/jats:sec>\n \n Objectives<\/jats:title>\n This manuscript reviews the substantial impact of chronic illness and cancer on sexual function from the perspectives of patients, partners, and healthcare providers. Convened by the Fifth International Consultation on Sexual Medicine, a multidisciplinary panel conducted a narrative review of current literature and expert consensus. The findings highlight both the direct and indirect effects of chronic diseases, breast and gynecological cancers, and oncological treatments on sexual health and relationships, emphasizing the importance of recognizing and addressing these issues to optimize care for individuals and their partners.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Narrative review of the existing literature and consensus recommendations from the expert panel.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n The direct and indirect impact of chronic disease and cancers and the impact of associated treatment interventions on sexual function and relationships is considerable.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n An understanding of the impact of chronic illness and cancers, and the related treatment of such can aid clinicians and researchers in providing optimal care to the individual and their partner(s).<\/jats:p>\n <\/jats:sec>","DOI":"10.1093\/sxmrev\/qeag002","type":"journal-article","created":{"date-parts":[[2026,1,26]],"date-time":"2026-01-26T10:15:29Z","timestamp":1769422529000},"source":"Crossref","is-referenced-by-count":0,"title":["Sexual function in chronic illness and cancer perspectives of the patient, partner, and healthcare provider; innovations; and updates: recommendations from the Fifth International Consultation on Sexual Medicine (ICSM 2024)"],"prefix":"10.1093","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3805-105X","authenticated-orcid":false,"given":"Kevan Richard","family":"Wylie","sequence":"first","affiliation":[{"name":"Retired; Department of Neurosciences, University of Sheffield , S10 2TN ,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5429-7714","authenticated-orcid":false,"given":"Michael G","family":"Kirby","sequence":"additional","affiliation":[{"name":"British Society of Sexual Medicine , WS14 9JL ,","place":["United Kingdom"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4253-5383","authenticated-orcid":false,"given":"Filippo Maria","family":"Nimbi","sequence":"additional","affiliation":[{"name":"Department of Theoretical and Applied Sciences (DiSTA), eCampus University , Via Isimbardi 10 - 22060 Novedrate ,","place":["Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4280-9177","authenticated-orcid":false,"given":"Michael","family":"Krychman","sequence":"additional","affiliation":[{"name":"University of California Irvine, Department OB\/GYN, Division of Gynecology, Oncology , Irvine, CA ,","place":["United States"]},{"name":"Southern California Center for Sexual Health and Survivorship Medicine , Newport Beach, CA ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9341-2407","authenticated-orcid":false,"given":"Jennifer Barsky","family":"Reese","sequence":"additional","affiliation":[{"name":"Fox Chase Cancer Center, Cancer Prevention and Control Program, \u00a0 Philadelphia 19111 PA ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6675-7482","authenticated-orcid":false,"given":"Deborah C","family":"Marshall","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai , New York, NY ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,2,23]]},"reference":[{"key":"2026042104262253800_ref1","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1111\/j.1743-6109.2009.01621.x","article-title":"Sexual function in chronic illness","volume":"7","author":"Basson","year":"2010","journal-title":"J Sex Med"},{"issue":"4_Part_2","key":"2026042104262253800_ref2","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1111\/j.1743-6109.2010.01779.x","article-title":"Cardiovascular aspects of sexual medicine","volume":"7","author":"Jackson","year":"2010","journal-title":"J Sex Med"},{"key":"2026042104262253800_ref3","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1111\/j.1743-6109.2009.01620.x","article-title":"Cancer and sexual problems","volume":"7","author":"Sadovsky","year":"2010","journal-title":"J Sex Med"},{"issue":"4","key":"2026042104262253800_ref4","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1016\/j.jsxm.2016.01.018","article-title":"Cancer, benign gynecology, and sexual function\u2014issues and answers","volume":"13","author":"Bennett","year":"2016","journal-title":"J Sex Med"},{"issue":"6","key":"2026042104262253800_ref5","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1016\/j.jsxm.2016.01.023","article-title":"Coronary heart disease, diabetes, and sexuality in men","volume":"13","author":"Hackett","year":"2016","journal-title":"J Sex Med"},{"issue":"1","key":"2026042104262253800_ref6","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s11894-024-00956-2","article-title":"Addressing factors that impact sexual well-being and intimacy in IBD patients","volume":"27","author":"Elias","year":"2025","journal-title":"Curr Gastroenterol Rep"},{"issue":"3","key":"2026042104262253800_ref7","doi-asserted-by":"publisher","first-page":"341","DOI":"10.7241\/ourd.20173.97","article-title":"Is sexology necessary in dermatology? 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