{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T12:20:10Z","timestamp":1778588410954,"version":"3.51.4"},"reference-count":29,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/pages\/standard-publication-reuse-rights"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Erectile dysfunction (ED) and benign prostatic hyperplasia (BPH) commonly coexist in aging men through shared vascular and neuroregulatory pathways, yet prevalence estimates vary widely across income settings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The objective of this study was to estimate the pooled prevalence of ED in men presenting with lower urinary tract symptoms (LUTS)\/BPH across clinical settings in high-income countries (HICs) and low- and middle-income countries (LMICs), and to narratively describe associated clinical and demographic factors reported within the included studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Following PRISMA guidelines, we searched 4 sources (Scopus, PubMed, Web of Science, and Lens.org) for English-language observational studies published between 2010 and 2025 reporting ED prevalence in men with LUTS\/BPH. Two reviewers independently screened titles\/abstracts and full texts, extracted data, and assessed risk of bias. A random-effects meta-analysis with logit-transformed prevalence estimates was conducted, with subgroup and sensitivity analyses used to explore heterogeneity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eleven studies (n\u2009=\u20091254 men with LUTS\/BPH) from 9 LMICs and 2 HICs yielded a pooled ED prevalence of 79.53% (95% confidence interval [CI], 71.63%-85.74%; I2\u00a0=\u200951.51%, P\u2009=\u2009.014), ranging from 60.0% (Morocco) to 98.7% (Bosnia and Herzegovina). LMICs showed higher rates (78.7%) than HICs (70.9%), though CIs overlapped. Tests of funnel-plot asymmetry suggested possible small-study effects, but these findings were interpreted cautiously given the limited number of studies. Narrative evidence suggested that age &amp;gt;60\u00a0years, LUTS, and cardiometabolic comorbidity were commonly reported correlates of ED.<\/jats:p>\n                    <jats:p>Conclusion: ED is highly prevalent among men with LUTS\/BPH presenting in hospital- or clinic-based settings. These findings support routine consideration of sexual health assessment in men presenting with LUTS\/BPH, while underscoring the need for prospective studies using standardized diagnostic criteria and broader sampling frames.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Registration<\/jats:title>\n                    <jats:p>PROSPERO CRD420251145482 https:\/\/www.crd.york.ac.uk\/PROSPERO\/view\/CRD420251145482<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/sxmrev\/qeag029","type":"journal-article","created":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T11:32:55Z","timestamp":1776771175000},"source":"Crossref","is-referenced-by-count":0,"title":["Prevalence of erectile dysfunction in men with lower urinary tract symptoms\/benign prostatic hyperplasia: a systematic review and meta-analysis"],"prefix":"10.1093","volume":"14","author":[{"given":"Sedrick","family":"Bukyana","sequence":"first","affiliation":[{"name":"Department of Surgery, Kampala International University , Western Campus, Ishaka Bushenyi ,","place":["Uganda"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul Clement","family":"Fillie","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kampala International University , Western Campus, Ishaka Bushenyi ,","place":["Uganda"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jackson","family":"Kakooza","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kampala International University , Western Campus, Ishaka Bushenyi ,","place":["Uganda"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8434-178X","authenticated-orcid":false,"given":"Catherine R","family":"Lewis","sequence":"additional","affiliation":[{"name":"Department of 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,","place":["Uganda"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Turyagumanawe","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kampala International University , Western Campus, Ishaka Bushenyi ,","place":["Uganda"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eunice","family":"Inomu","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kampala International University , Western Campus, Ishaka Bushenyi ,","place":["Uganda"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed Kiswezi","family":"Kazigo","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kampala International University , Western Campus, Ishaka Bushenyi ,","place":["Uganda"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eltahir Ahmed","family":"Eltahir","sequence":"additional","affiliation":[{"name":"Department of Surgery, Kampala International University , Western 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