{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T17:23:19Z","timestamp":1783012999438,"version":"3.54.6"},"reference-count":42,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T00:00:00Z","timestamp":1782950400000},"content-version":"vor","delay-in-days":2,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,6,30]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>This review explores the relationship between obsessive-compulsive disorder (OCD) and sexual functioning.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The aim is to highlight the clinical relevance of sexual health in OCD and encourage more comprehensive assessment and intervention strategies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study explores the association between OCD symptoms and genital pain or sexual functioning, using the Desire, Excitement, Plateau, Orgasm, Resolution model as a conceptual framework. We conducted a Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020-compliant systematic review, searching PsycINFO, MEDLINE, Scopus, and Web of Science for studies published until February 26, 2026, including adult participants assessed for OCD symptoms and at least one phase of the sexual response cycle or genital pain. Data extracted included study design, participant characteristics, assessment tools, and the sexual functioning domains evaluated. Quality assessment was performed using the QUIPS Tool.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We included 13 articles. OCD symptoms are associated with sexual desire, arousal, and female orgasm dysfunctions, likely due to the cognitive, emotional, and behavioral rigidity associated with the disorder. These interferences can impact both individual well-being and relationship satisfaction. No consistent evidence emerged regarding the association between OCD symptoms and male orgasmic function or genital pain; therefore, the currently available findings do not allow firm conclusions to be drawn about these relationships. Given the limited number of specific studies on this topic, further research is needed to improve clinical understanding and inform tailored treatment approaches that address both psychopathology and sexual health.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The results of this study emphasize the association of sexual dysfunctions and OCD symptoms and the importance of evaluating sexual functioning in these patients, with a focus on enhancing their quality of life.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/sxmrev\/qeag044","type":"journal-article","created":{"date-parts":[[2026,6,16]],"date-time":"2026-06-16T12:18:02Z","timestamp":1781612282000},"source":"Crossref","is-referenced-by-count":0,"title":["The interplay between the obsessive-compulsive disorder and sexual function: a systematic review"],"prefix":"10.1093","volume":"14","author":[{"given":"Davide","family":"Doroldi","sequence":"first","affiliation":[{"name":"Department of Dynamic and Clinical Psychology, and Health Studies, Sapienza University of Rome , Rome ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Cialini","sequence":"additional","affiliation":[{"name":"Department of Dynamic and Clinical Psychology, and Health Studies, Sapienza University of Rome , Rome ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giulia","family":"Origlia","sequence":"additional","affiliation":[{"name":"Department of Dynamic and Clinical Psychology, and Health Studies, Sapienza University of Rome , Rome ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tessa","family":"Giannini","sequence":"additional","affiliation":[{"name":"Department of Dynamic and Clinical Psychology, and Health Studies, Sapienza University of Rome , Rome ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Blasutto","sequence":"additional","affiliation":[{"name":"Department of Psychology, University of Rome \u201cSapienza\u201d , Rome 00185 ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Del Casale","sequence":"additional","affiliation":[{"name":"Department of Dynamic and Clinical Psychology, and Health Studies, Sapienza University of Rome , Rome ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grazia","family":"Spitoni","sequence":"additional","affiliation":[{"name":"Department of Dynamic and Clinical Psychology, and Health Studies, Sapienza University of Rome , Rome ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tommaso","family":"Boldrini","sequence":"additional","affiliation":[{"name":"Department of Psychology and Health Science, Pegaso Digital University , Naples ,","place":["Italy"]},{"name":"Department of Psychiatry, University of Ottawa , Ottawa ,","place":["Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giacomo","family":"Ciocca","sequence":"additional","affiliation":[{"name":"Department of Wellbeing , Health and Environmental Sustainability, Sapienza University of Rome, Rome ,","place":["Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2026,7,2]]},"reference":[{"issue":"3","key":"2026070212235285800_ref1","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1111\/cpsp.12076","article-title":"Obsessive-compulsive disorder in the DSM-5","volume":"21","author":"Abramowitz","year":"2014","journal-title":"Clin Psychol Sci Pract"},{"key":"2026070212235285800_ref2","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596","volume-title":"Diagnostic and Statistical Manual of Mental Disorders (5 th)","author":"American Psychiatric Association","year":"2013"},{"key":"2026070212235285800_ref3","volume-title":"Obsessions and Compulsions. Prentice Hall, Ed.","author":"Rachman","year":"1980"},{"key":"2026070212235285800_ref4","first-page":"277","volume-title":"The Psychology of Goals","author":"Liberman","year":"2009"},{"key":"2026070212235285800_ref5","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1016\/j.jbtep.2014.11.003","article-title":"Can doubt attenuate access to internal states? Implications for obsessive-compulsive disorder","volume":"49","author":"Lazarov","year":"2015","journal-title":"J Behav Ther Exp Psychiatry"},{"key":"2026070212235285800_ref6","doi-asserted-by":"publisher","first-page":"711","DOI":"10.1080\/14681994.2021.2009793","article-title":"Sexual dysfunction in relationship obsessive compulsive disorder","volume":"39","author":"Derby","year":"2021","journal-title":"Sex Relatsh Ther"},{"issue":"4","key":"2026070212235285800_ref7","doi-asserted-by":"publisher","first-page":"351","DOI":"10.1080\/713697434","article-title":"Erectile dysfunction: an empirical approach based on Beck\u2019s cognitive theory","volume":"15","author":"Nobre","year":"2000","journal-title":"Sex Relatsh Ther"},{"issue":"7","key":"2026070212235285800_ref8","doi-asserted-by":"publisher","first-page":"573","DOI":"10.1016\/j.cpr.2009.06.007","article-title":"Sexual dysfunction in depression and anxiety: conceptualizing sexual dysfunction as part of an internalizing dimension","volume":"29","author":"Laurent","year":"2009","journal-title":"Clin Psychol Rev"},{"issue":"1","key":"2026070212235285800_ref9","doi-asserted-by":"publisher","first-page":"23","DOI":"10.2217\/npy.12.72","article-title":"Sexuality and obsessive-compulsive disorder: the hidden affair","volume":"3","author":"Real","year":"2013","journal-title":"Neuropsychiatry"},{"key":"2026070212235285800_ref10","doi-asserted-by":"publisher","first-page":"1077337","DOI":"10.3389\/fpsyt.2022.1077337","article-title":"Sense of happiness and other aspects of quality of life in patients with obsessive-compulsive disorder","volume":"13","author":"\u017berdzi\u0144ski","year":"2022","journal-title":"Front Psychiatry"},{"issue":"2","key":"2026070212235285800_ref11","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1097\/00004714-200004000-00002","article-title":"Evaluation of sexual functioning in depressed outpatients: a double-blind comparison of sustained-release bupropion and sertraline treatment","volume":"20","author":"Segraves","year":"2000","journal-title":"J Clin Psychopharmacol"},{"issue":"4","key":"2026070212235285800_ref12","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1016\/j.ucl.2007.08.003","article-title":"Sexual dysfunction associated with antidepressant therapy","volume":"34","author":"Segraves","year":"2007","journal-title":"Urol Clin N Am"},{"key":"2026070212235285800_ref13","first-page":"273","volume-title":"Handbook of Clinical Sexuality for Mental Health Professionals","author":"Segraves","year":"2016"},{"key":"2026070212235285800_ref14","doi-asserted-by":"publisher","first-page":"1043","DOI":"10.2147\/NDT.S185757","article-title":"Selective serotonin reuptake inhibitor-induced sexual dysfunction: current management perspectives","volume":"Volume 16","author":"Atmaca","year":"2020","journal-title":"Neuropsychiatr Dis Treat"},{"key":"2026070212235285800_ref15","volume-title":"Sessuologia Medica. Trattato di Psicosessuologia, Medicina Della sessualit\u00e0 e Salute Della Coppia (2nd Ed.)","author":"Jannini","year":"2017"},{"key":"2026070212235285800_ref16","volume-title":"Human Sexual Response","author":"Masters","year":"1966"},{"key":"2026070212235285800_ref17","volume-title":"The New Sex Therapy: Active Treatment of Sexual Dysfunctions","author":"Kaplan","year":"1974"},{"key":"2026070212235285800_ref18","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/j.jclinepi.2021.02.003","article-title":"Updating guidance for reporting systematic reviews: development of the PRISMA 2020 statement","volume":"134","author":"Page","year":"2021","journal-title":"J Clin Epidemiol"},{"key":"2026070212235285800_ref19","doi-asserted-by":"publisher","first-page":"1027","DOI":"10.1016\/j.envint.2018.07.015","article-title":"Identifying the PECO: a framework for formulating good questions to explore the association of environmental and other exposures with health outcomes","volume":"121","author":"Morgan","year":"2018","journal-title":"Environ Int"},{"issue":"4","key":"2026070212235285800_ref20","doi-asserted-by":"publisher","first-page":"280","DOI":"10.7326\/0003-4819-158-4-201302190-00009","article-title":"Assessing bias in studies of prognostic factors","volume":"158","author":"Hayden","year":"2013","journal-title":"Ann Intern Med"},{"key":"2026070212235285800_ref21","doi-asserted-by":"publisher","DOI":"10.4324\/9780203771587","volume-title":"Statistical Power Analysis for the Behavioral Sciences","author":"Cohen","year":"2013"},{"issue":"19","key":"2026070212235285800_ref22","doi-asserted-by":"publisher","first-page":"e158966","DOI":"10.5812\/ijpbs-151592","article-title":"Exploring the relationship between obsessive-compulsive disorder and chronic prostatitis\/chronic pelvic pain syndrome: a case-control study","volume":"19","author":"Mishani","year":"2025","journal-title":"IJ Psychiatry Behav Sci"},{"issue":"10","key":"2026070212235285800_ref23","doi-asserted-by":"publisher","first-page":"1802","DOI":"10.3390\/medicina61101802","article-title":"Association between alexithymia, sexual dysfunctions, and dyadic adjustment in obsessive\u2013compulsive disorder","volume":"61","author":"Sun","year":"2025","journal-title":"Medicina"},{"issue":"2","key":"2026070212235285800_ref24","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1177\/26318318251324316","article-title":"Sexual functioning in females with OCD: a comparative cross-sectional study","volume":"7","author":"Jaiswal","year":"2025","journal-title":"J Psychosex Health"},{"issue":"2","key":"2026070212235285800_ref25","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1038\/ijir.2014.34","article-title":"Psychological determinants of erectile dysfunction among middle-aged men","volume":"27","author":"Aghighi","year":"2015","journal-title":"Int J Impot Res"},{"issue":"2","key":"2026070212235285800_ref26","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1111\/j.1743-6109.2010.02092.x","article-title":"Personality traits and psychopathology on male sexual dysfunction: an empirical study","volume":"8","author":"Quinta Gomes","year":"2011","journal-title":"J Sex Med"},{"issue":"1","key":"2026070212235285800_ref27","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1080\/14681990050001556","article-title":"The interaction between anxiety and sexual functioning: a controlled study of sexual functioning in women with anxiety disorders","volume":"15","author":"Van Minnen","year":"2000","journal-title":"Sex Relatsh Ther"},{"issue":"4","key":"2026070212235285800_ref28","first-page":"381","article-title":"Sexual dysfunction in obsessive compulsive disorder and panic disorder","volume":"24","author":"Aksoy","year":"2012","journal-title":"Psychiatr Danub"},{"issue":"3","key":"2026070212235285800_ref29","doi-asserted-by":"publisher","first-page":"409","DOI":"10.4081\/ripppo.2019.409","article-title":"The role of disgust propensity and sensitivity on sexual excitations and inhibition in obsessive-compulsive disorder","volume":"22","author":"Pozza","year":"2019","journal-title":"Res Psychother"},{"issue":"9","key":"2026070212235285800_ref30","doi-asserted-by":"publisher","first-page":"694","DOI":"10.1097\/NMD.0000000000001184","article-title":"Sexual arousal in obsessive-compulsive disorder with and without contamination\/washing symptoms a moderating role of disgust sensitivity","volume":"208","author":"Pozza","year":"2020","journal-title":"J Nerv Ment Dis"},{"issue":"1","key":"2026070212235285800_ref31","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.jad.2005.12.006","article-title":"Sexual pleasure in women with obsessive-compulsive disorder?","volume":"91","author":"Vulink","year":"2006","journal-title":"J Affect Disord"},{"issue":"3\u20134","key":"2026070212235285800_ref32","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1080\/01674820400024463","article-title":"Psychological difficulties within a group of patients with vulvodynia","volume":"25","author":"Wylie","year":"2004","journal-title":"J Psychosom Obstet Gynecol"},{"issue":"4","key":"2026070212235285800_ref33","doi-asserted-by":"publisher","first-page":"299","DOI":"10.4088\/pcc.v10n0405","article-title":"Major depressive disorder, obsessive-compulsive disorder, and generalized anxiety disorder: do the sexual dysfunctions differ?","volume":"10","author":"Kendurkar","year":"2008","journal-title":"Primary Care Companion J Clin Psychiatry"},{"issue":"5","key":"2026070212235285800_ref34","doi-asserted-by":"publisher","first-page":"528","DOI":"10.1017\/S1092852920001649","article-title":"Sexual response in obsessive\u2013compulsive disorder: the role of obsessive beliefs","volume":"26","author":"Pozza","year":"2021","journal-title":"CNS Spectrums"},{"issue":"3\u20134","key":"2026070212235285800_ref35","doi-asserted-by":"publisher","first-page":"247","DOI":"10.1080\/00224499.2012.746280","article-title":"Giving In to arousal or staying stuck in disgust? Disgust-based mechanisms in sex and sexual dysfunction","volume":"50","author":"de Jong","year":"2013","journal-title":"J Sex Res"},{"key":"2026070212235285800_ref36","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1007\/978-3-319-52539-6_6","volume-title":"The Textbook of Clinical Sexual Medicine","author":"Pahwa","year":"2017"},{"key":"2026070212235285800_ref37","first-page":"64","volume-title":"Anxiety and its Disorders: The Nature and Treatment of Anxiety and Panic","author":"Barlow","year":"2002","edition":"2"},{"issue":"4","key":"2026070212235285800_ref38","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1016\/j.brat.2005.03.009","article-title":"The effects of state and trait self-focused attention on sexual arousal in sexually functional and dysfunctional women","volume":"44","author":"Meston","year":"2006","journal-title":"Behav Res Ther"},{"issue":"4","key":"2026070212235285800_ref39","doi-asserted-by":"publisher","first-page":"328","DOI":"10.1080\/0092623X.2018.1526838","article-title":"Spectatoring mediates the association between penis appearance concerns and sexual dysfunction","volume":"45","author":"Wyatt","year":"2019","journal-title":"J Sex Marital Ther"},{"issue":"1","key":"2026070212235285800_ref40","doi-asserted-by":"publisher","first-page":"S52","DOI":"10.1038\/sj.ijir.3901429","article-title":"Sexual dysfunction in the elderly: age or disease?","volume":"17","author":"Camacho","year":"2005","journal-title":"Int J Impot Res"},{"issue":"3","key":"2026070212235285800_ref41","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1111\/j.1743-6109.2005.20356.x","article-title":"The impact of aging on sexual function and sexual dysfunction in women: a review of population-based studies","volume":"2","author":"Hayes","year":"2005","journal-title":"J Sex Med"},{"issue":"1","key":"2026070212235285800_ref42","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1017\/S0033291799001452","article-title":"Does old age reduce the risk of anxiety and depression? A review of epidemiological studies across the adult life span","volume":"30","author":"Jorm","year":"2000","journal-title":"Psychol Med"}],"container-title":["Sexual Medicine Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/smr\/article-pdf\/14\/3\/qeag044\/68683395\/qeag044.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/smr\/article-pdf\/14\/3\/qeag044\/68683395\/qeag044.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T16:55:42Z","timestamp":1783011342000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/smr\/article\/doi\/10.1093\/sxmrev\/qeag044\/8723665"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,30]]},"references-count":42,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,6,30]]}},"URL":"https:\/\/doi.org\/10.1093\/sxmrev\/qeag044","relation":{},"ISSN":["2050-0513","2050-0521"],"issn-type":[{"value":"2050-0513","type":"print"},{"value":"2050-0521","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2026,7]]},"published":{"date-parts":[[2026,6,30]]},"article-number":"qeag044"}}