{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T01:51:41Z","timestamp":1791597101299,"version":"4.3.4"},"reference-count":452,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T00:00:00Z","timestamp":1791590400000},"content-version":"vor","delay-in-days":10,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,30]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Disorders of ejaculation, including premature ejaculation (PE) and delayed ejaculation (DE), are common conditions with a substantial impact on men\u2019s quality of life and their relationships. This review synthesizes the latest findings on their etiology, epidemiology, evaluation, and management. This study aims to present evidence-based recommendations for the definition, classification, and treatment of PE and DE, developed under the guidance of the Fifth International Consultation on Sexual Medicine.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A multidisciplinary panel conducted a narrative review of global literature and utilized a modified Delphi method to develop consensus recommendations. Evidence was graded using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Premature ejaculation is the most frequently reported male sexual complaint, classified into lifelong, acquired, variable, and subjective subtypes. Evidence-based management includes medical therapies such as selective serotonin reuptake inhibitors, topical anesthetics, and psychotherapeutic approaches. Although less common, DE remains under-researched, with limited pharmacological and behavioral treatment options. Definitions for both disorders have evolved to incorporate timing, distress, and control criteria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Understanding the pathophysiology and adopting individualized approaches to managing PE and DE can improve patient outcomes. Further research is needed to enhance the evidence-based therapies, particularly for DE.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1093\/sxmrev\/qeag068","type":"journal-article","created":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T11:16:50Z","timestamp":1788520610000},"source":"Crossref","is-referenced-by-count":0,"title":["Contemporary consensus and emerging directions in premature and delayed ejaculation: recommendations from the 5th International Consultation on Sexual Medicine"],"prefix":"10.1093","volume":"14","author":[{"given":"Ege C","family":"Serefoglu","sequence":"first","affiliation":[{"name":"Department of Urology, Biruni University School of Medicine , Sisli 34365 Istanbul ,","place":["Turkey"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan W","family":"Shindel","sequence":"additional","affiliation":[{"name":"Department of Urology, University of California, San Francisco , San Francisco , CA, 94143-0738,","place":["United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Infertility and Sexual Medicine, Third Affiliated Hospital, Sun Yat-sen University , Guangzhou ,","place":["China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eelke","family":"Snoeren","sequence":"additional","affiliation":[{"name":"Department of Psychology, UiT The Arctic University of Norway , N-9037 Tromso ,","place":["Norway"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2067-9383","authenticated-orcid":false,"given":"Gajanan","family":"Bhat","sequence":"additional","affiliation":[{"name":"TSS Shripad Hegde Kadave Institute of Medical Sciences and PG Hospital , Sirsi - 581 402,","place":["India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0107-8857","authenticated-orcid":false,"given":"Mohamed","family":"Arafa","sequence":"additional","affiliation":[{"name":"Department of Andrology, Sexology, and STIs, Faculty of Medicine, Cairo University , Giza, 12613 ,","place":["Egypt"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanley","family":"Althof","sequence":"additional","affiliation":[{"name":"Center for Marital and Sexual Health of South Florida , Greenacres, FL 33467, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amr","family":"El-Meliegy","sequence":"additional","affiliation":[{"name":"Department of Andrology, Sexology, and STIs, Faculty of Medicine, Cairo University , Giza, 12613 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