{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:34:59Z","timestamp":1787009699221,"version":"build-2736575974"},"reference-count":212,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2020,5,21]],"date-time":"2020-05-21T00:00:00Z","timestamp":1590019200000},"content-version":"vor","delay-in-days":50,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Postweaning mortality is a complex causal matrix involving animal, environment, and infectious etiologic factors. Despite advances in swine productivity such as total pigs born, growth rate, feed intake, and efficiency, there have been modest to no improvements in postweaning mortality rates over the last several years. Industry averages for postweaning mortality range from four to eight percent for each the nursery, grow-finish, or wean-finish stages. Retrospective mortality causal analyses of individual databases have been performed. However, little information derived from meta-analysis, systematic review, or comprehensive literature reviews are available. In order to develop and evaluate strategies to comprehensively manage and reduce postweaning mortality, addressing the complexity and range of impact that factors have on mortality is necessary to identify and prioritize such contributing factors. Our objective is to describe the current state of knowledge regarding non-infectious causes of postweaning mortality, focusing on estimates of frequency and magnitude of effect where available. Postweaning mortality can be generalized into non-infectious and infectious causes, with non-infectious factors further classified into anatomic abnormalities, toxicity, animal factors, facility factors, nutritional inadequacies, season, and management factors. Important non-infectious factors that have been identified through review of literature include birth weight, pre-weaning management, weaning age and weight, and season. Additionally, reasons for mortality with a low incidence but a high magnitude include abdominal organ torsion\/volvulus, sodium ion or ionophore toxicosis, or dietary imbalance due to feed formulation or manufacture error. Many interactive effects are present between and among infectious and non-infectious factors, but an important trend is the impact that non-infectious factors have on the incidence, severity, and resolution of infectious disease. Strategies to reduce postweaning mortality must consider the dynamic, complex state that forms the causal web. Control of postweaning mortality through understanding of the complexity, evaluation of mortality reduction strategies through rigorous scientific evaluation, and implementation remains an area of opportunity for continued growth and development in the global swine industry.<\/jats:p>","DOI":"10.1093\/tas\/txaa068","type":"journal-article","created":{"date-parts":[[2020,5,21]],"date-time":"2020-05-21T10:28:12Z","timestamp":1590056892000},"page":"462-484","source":"Crossref","is-referenced-by-count":37,"title":["Postweaning mortality in commercial swine production. I: review of non-infectious contributing factors"],"prefix":"10.1093","volume":"4","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6144-6714","authenticated-orcid":false,"given":"Jordan T","family":"Gebhardt","sequence":"first","affiliation":[{"name":"Department of Animal Sciences and Industry, College of Agriculture, Kansas State University, Manhattan, KS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mike D","family":"Tokach","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences and Industry, College of Agriculture, Kansas State University, Manhattan, KS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6371-0729","authenticated-orcid":false,"given":"Steve S","family":"Dritz","sequence":"additional","affiliation":[{"name":"Department of Diagnostic Medicine\/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joel M","family":"DeRouchey","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences and Industry, College of Agriculture, Kansas State University, Manhattan, KS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason C","family":"Woodworth","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences and Industry, College of Agriculture, Kansas State University, Manhattan, KS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert D","family":"Goodband","sequence":"additional","affiliation":[{"name":"Department of Animal Sciences and Industry, College of Agriculture, Kansas State University, Manhattan, KS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steve C","family":"Henry","sequence":"additional","affiliation":[{"name":"Abilene Animal Hospital, P.A., Abilene, KS"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,5,21]]},"reference":[{"key":"2020072914373873700_CIT0001","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1017\/S1751731113001912","article-title":"Management factors affecting mortality, feed intake and feed conversion ratio of grow-finishing pigs","volume":"8","author":"Agostini","year":"2014","journal-title":"Animal"},{"key":"2020072914373873700_CIT0002","doi-asserted-by":"crossref","first-page":"371","DOI":"10.5424\/sjar\/2013112-3011","article-title":"Descriptive study of production factors affecting performance traits in growing-finishing pigs in Spain","volume":"11","author":"Agostini","year":"2013","journal-title":"Span. 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