{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T00:05:26Z","timestamp":1765584326469,"version":"3.48.0"},"reference-count":35,"publisher":"Oxford University Press (OUP)","license":[{"start":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T00:00:00Z","timestamp":1761696000000},"content-version":"vor","delay-in-days":301,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["2662025PY003"],"award-info":[{"award-number":["2662025PY003"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["2662025DKPY006"],"award-info":[{"award-number":["2662025DKPY006"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,7]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Three experiments were conducted to evaluate the effects of incorporating Saccharomyces cerevisiae fermented Moutai distiller\u2019s grains (FMDG) into diets for growing-finishing pigs across three body weight (BW) phases: 30 to 50\u2009kg (Exp. 1), 50 to 75\u2009kg (Exp. 2), and 90 to 130\u2009kg (Exp. 3). The experimental diets were corn-soybean meal based with 0%, 5% or 10% FMDG. Metabolomic analysis revealed that fermentation enriched FMDG with beneficial compounds, including carbohydrates, quercetin, and tripeptides, compared to unfermented Moutai dried distiller\u2019s grains. Results form the animal experiments showed that dietary inclusion of FMDG at levels up to 10% did not adversely affect growth performance in any phase. Notably, 5% FMDG inclusion during the later finishing phase (90 to 130\u2009kg) significantly increased (P\u2009&amp;lt;\u20090.05) average daily feed intake (ADFI) and numerically improved average daily gain (ADG) and feed conversion ratio (FCR), reducing meat production cost by 0.54 RMB\/kg. Apparent total tract digestibility (ATTD) of nutrients varied by phase, with enhanced crude protein and calcium utilization at 30 to 50\u2009kg but reduced (P\u2009&amp;lt;\u20090.05) calcium digestibility at 90 to 130\u2009kg. In later finishing pigs, inclusion of 5% and 10% FMDG significantly decreased (P\u2009&amp;lt;\u20090.05) serum endotoxin, diamine oxidase, and interleukin-6 levels. We further confirmed that dietary inclusion of FMDG increased (P\u2009&amp;lt;\u20090.05) the expression of tight junction proteins including claudin-4, occludin, and zonula occludens protein-1 (ZO-1) in the jejunum. Carcass traits and meat quality were maintained or improved, with increased (P\u2009&amp;lt;\u20090.05) loin eye area and meat redness (a*) in the 5% FMDG group. Overall, these findings demonstrate that FMDG can be effectively included at up to 10% in swine diets without compromising animal health and performance, with 5% FMDG providing particularly beneficial for later finishing pigs due to its positive impacts in improving feed efficiency, carcass traits and meat quality, as well as enhancing intestinal integrity.<\/jats:p>","DOI":"10.1093\/tas\/txaf143","type":"journal-article","created":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T11:33:36Z","timestamp":1761046416000},"source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of\n                    <i>Saccharomyces cerevisiae<\/i>\n                    fermented Moutai distiller\u2019s grains as an alternative ingredient for growing-finishing pigs"],"prefix":"10.1093","volume":"9","author":[{"given":"Chunqi","family":"Lu","sequence":"first","affiliation":[{"name":"Kweichow Moutai (Group) Circular Economy Industrial Investment and Development Co., Ltd , Zunyi 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Sustainable Production, College of Animal Science and Technology, Huazhong Agricultural University , Wuhan 430070,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youfeng","family":"Jiang","sequence":"additional","affiliation":[{"name":"Kweichow Moutai (Group) Circular Economy Industrial Investment and Development Co., Ltd , Zunyi 563000,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiuyue","family":"Fu","sequence":"additional","affiliation":[{"name":"National Key Laboratory of Agricultural Microbiology , Wuhan 430070,","place":["China"]},{"name":"Frontiers Science Center for Animal Breeding and Sustainable Production, College of Animal Science and Technology, Huazhong Agricultural University , Wuhan 430070,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huixin","family":"Xiong","sequence":"additional","affiliation":[{"name":"Kweichow Moutai (Group) Circular Economy Industrial 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