{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T23:18:57Z","timestamp":1740179937612,"version":"3.37.3"},"reference-count":43,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2019,6,13]],"date-time":"2019-06-13T00:00:00Z","timestamp":1560384000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100001003","name":"Boehringer Ingelheim","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001003","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The objective of this experiment was to evaluate effects of extended-release eprinomectin on fescue toxicosis and impacts on performance and reproduction in fall-calving beef cows. Fall-calving Angus \u00d7 Simmental multiparous cows [n = 335; age = 5.8 \u00b1 2.1 yr; 586.5 \u00b1 6.0 kg body weight (BW); 5.48 \u00b1 0.05 body condition score (BCS)] were stratified by BW, age, and BCS and randomly assigned to one of three treatments. Treatments included a spring injection of extended-release eprinomectin (SERE) on day 0, a fall injection of extended-release eprinomectin injection (FERE) on day 84, and a saline control (CON). All treatments were administered at a rate of 1 mL\/50 kg BW. Prior to the experiment, all cows were treated with oral fenbendazole to minimize parasite load. Cows grazed endophyte-infected tall fescue. Hair coat score (HCS), BW, and BCS were recorded on all cattle. Fecal egg count (FEC), respiration rate (RR), horn fly and tick count, hematocrit (% packed cell volume, PCV), and serum prolactin were analyzed on a subset of cows (35\/treatment). On day 194, cows were artificially inseminated (AI) and 11 d following AI were exposed to bulls for 51 d. Milk production was estimated on day 210 on a subset of 85 cow\u2013calf pairs (28\u201329\/treatment). There was a tendency for a treatment \u00d7 time interaction (P = 0.07) for FEC likely driven by an increase in FEC of the CON cattle at day 126 compared to SERE and FERE. There was a tendency for a treatment \u00d7 time interaction (P = 0.06) for cow BW, largely driven by time differences; however, there was no effect of treatment (P = 0.84) on BW. There was no difference (P \u2265 0.13) in cow PCV, fly and tick count, BCS, HCS, RR, and serum prolactin throughout the experiment. Additionally, there was no difference (P \u2265 0.46) in Julian calving date, calf birth BW, or milk production between treatments. Interestingly, heifer calves born to FERE dams tended to have greater (P = 0.06) weaning BW compared to heifer calves born to CON dams. In addition, there was no difference (P \u2265 0.17) in heat patch scores, AI conception rates, or overall pregnancy rates between treatments. Extended-release eprinomectin did not impact cow growth performance, reproductive performance or fescue toxicity symptoms when grazing endophyte-infected tall fescue; however, calf weaning BW tended to be improved.<\/jats:p>","DOI":"10.1093\/tas\/txz093","type":"journal-article","created":{"date-parts":[[2019,6,13]],"date-time":"2019-06-13T08:30:13Z","timestamp":1560414613000},"page":"1423-1434","source":"Crossref","is-referenced-by-count":1,"title":["Effects of extended-release eprinomectin on fescue toxicosis, performance, and reproduction on fall-calving beef cows"],"prefix":"10.1093","volume":"3","author":[{"given":"Mareah J","family":"Volk","sequence":"first","affiliation":[{"name":"Department of Animal Sciences, University of Illinois, Urbana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taylor R","family":"Krause","sequence":"first","affiliation":[{"name":"Department of Animal Sciences, University of Illinois, Urbana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rebecca S","family":"Stokes","sequence":"first","affiliation":[{"name":"Department of Animal Sciences, University of Illinois, Urbana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank A","family":"Ireland","sequence":"first","affiliation":[{"name":"Department of Animal Sciences, University of Illinois, Urbana"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel W","family":"Shike","sequence":"first","affiliation":[{"name":"Department of Animal Sciences, University of Illinois, Urbana"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2019,6,13]]},"reference":[{"key":"2020051902390837600_CIT0001","doi-asserted-by":"publisher","first-page":"5878","DOI":"10.2527\/jas.2012-5964","article-title":"Postgraze assessment of toxicosis symptoms for steers grazed on toxic endophyte-infected tall fescue pasture","volume":"91","author":"Aiken","year":"2013","journal-title":"J. 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