{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T10:15:01Z","timestamp":1789035301122,"version":"build-2803163510"},"reference-count":45,"publisher":"Oxford University Press (OUP)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2005,10,1]]},"DOI":"10.1093\/toxsci\/kfi249","type":"journal-article","created":{"date-parts":[[2005,7,28]],"date-time":"2005-07-28T00:44:36Z","timestamp":1122511476000},"page":"391-398","source":"Crossref","is-referenced-by-count":82,"title":["Evaluation of Estrogenic Activities of Aquatic Herbicides and Surfactants Using an Rainbow Trout Vitellogenin Assay"],"prefix":"10.1093","volume":"87","author":[{"given":"Lingtian","family":"Xie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kelly","family":"Thrippleton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary Ann","family":"Irwin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffrey S.","family":"Siemering","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdou","family":"Mekebri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Crane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Berry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Schlenk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2005,7,27]]},"reference":[{"key":"key\n\t\t\t\t20171012060128_BIB1","doi-asserted-by":"crossref","unstructured":"Allen, Y., Scott, A. P., Matthiessen, P., Haworth, S., Thain, J. E., and Feist, S. (1999). Survey of estrogenic activity in United Kingdom estuarine and coastal waters and its effects on gonadal development of the flounder Platichthys flesus.Environ. Toxicol. Chem.18,1791\u20131800.","DOI":"10.1002\/etc.5620180827"},{"key":"key\n\t\t\t\t20171012060128_BIB2","doi-asserted-by":"crossref","unstructured":"Almstrup, K., Fernandez, M. F., Peterson, J. H., Olea, N., Skakkebak, N. E., and Leffers, H. (2002). Dual effects of phytoestrogens results in U-shape dose-response curves. Environ. Health Perspect.110,743\u2013748.","DOI":"10.1289\/ehp.02110743"},{"key":"key\n\t\t\t\t20171012060128_BIB3","doi-asserted-by":"crossref","unstructured":"Altenburger, R., Nendza, M., and Schuurmann, G. (2003). Mixture toxicity and its modeling by quantitative structure-activity relationships. Environ. Toxicol. Chem.22,1900\u20131915.","DOI":"10.1897\/01-386"},{"key":"key\n\t\t\t\t20171012060128_BIB5","doi-asserted-by":"crossref","unstructured":"Andersen, H. R., Vinggaard, A. M., Rasmussen, T. H., Gjermandsen, I. M., and Bonefeld-Jorgensen, E. C. (2002). Effects of currently used pesticides in assays for estrogenicity, androgenicity, and aromatase activity in vitro. Toxicol. Appl. Pharmacol.179,1\u201312.","DOI":"10.1006\/taap.2001.9347"},{"key":"key\n\t\t\t\t20171012060128_BIB6","doi-asserted-by":"crossref","unstructured":"Anderson, M. J., Olsen, H., Matsumura, F., and Hinton, D. E. (1996). In vivo modulation of 17 beta-estradiol-induced vitellogenin synthesis and estrogen receptor in rainbow trout (Oncorhynchus mykiss) liver cells by beta-naphthoflavone. Toxicol. Appl. Pharmacol.137,210\u2013218.","DOI":"10.1006\/taap.1996.0074"},{"key":"key\n\t\t\t\t20171012060128_BIB45","doi-asserted-by":"crossref","unstructured":"Bj\u00f6rn, T., Gunter, K., and Schwunger, M. J. (1997). Alkylphenol ethoxylates: Trace analysis and environmental behavior. Chem. Rev.97,3247\u20133272.","DOI":"10.1021\/cr970323m"},{"key":"key\n\t\t\t\t20171012060128_BIB8","doi-asserted-by":"crossref","unstructured":"Calabrese, E. J., and Baldwin, L. A. (2001). U-shaped dose-responses in biology, toxicology, and public health. Ann. Rev. Pub. Health22,15\u201333.","DOI":"10.1146\/annurev.publhealth.22.1.15"},{"key":"key\n\t\t\t\t20171012060128_BIB9","doi-asserted-by":"crossref","unstructured":"Crosby, D. G., and Tutass, H. O. (1966). Photodecomposition of 2,4-dichlorophenoxyacetic acid. J. Agric. Food Chem.14,596\u2013599.","DOI":"10.1021\/jf60148a012"},{"key":"key\n\t\t\t\t20171012060128_BIB10","doi-asserted-by":"crossref","unstructured":"Hemmer, M. J., Bowman, C. J., Hemmer, B. L., Friedman, S. D., Marcovich, D., Kroll, K. J., and Denslow, N. D. (2002). Vitellogenin mRNA regulation and plasma clearance in male sheepshead minnows, (Cyprinodon variegatus) after cessation of exposure to 17\u03b2-estradiol and p-nonylphenol. Aquat. Toxicol.58,99\u2013112.","DOI":"10.1016\/S0166-445X(01)00238-7"},{"key":"key\n\t\t\t\t20171012060128_BIB11","doi-asserted-by":"crossref","unstructured":"Heppell, S. A., Denslow, N. D., Folmar, L. C., and Sullivan, C. V. (1995). Universal assay for vitellogenin as a biomarker for environmental estrogens. Environ. Health Perspect.103,9\u201315.","DOI":"10.1289\/ehp.95103s79"},{"key":"key\n\t\t\t\t20171012060128_BIB14","doi-asserted-by":"crossref","unstructured":"Huggett, D. B., Foran, C. M., Brooks, B. W., Weston, J., Peterson, B., Marsh, K. E., La Point, T. W., and Schlenk, D. (2003). Comparison of in vitro and in vivo bioassay for estrogenicity in effluent from North American municipal wastewater facilities. Toxicol. Sci.72,77\u201383.","DOI":"10.1093\/toxsci\/kfg017"},{"key":"key\n\t\t\t\t20171012060128_BIB15","doi-asserted-by":"crossref","unstructured":"James, M. O., and Bend, J. R. (1976). Taurine conjugation of 2,4-Dichlorophenoxyacetic acid and phenylacetic acid in two marine species. Xenobiotica6,393\u2013398.","DOI":"10.3109\/00498257609151651"},{"key":"key\n\t\t\t\t20171012060128_BIB16","doi-asserted-by":"crossref","unstructured":"Jobling, S., Nolan, M., Tyler, C. R., Brighty, G. C., and Sumpter, J. P. (1998). Widespread sexual disruption in wild fish. Environ. Sci. Technol.32,2498\u20132506.","DOI":"10.1021\/es9710870"},{"key":"key\n\t\t\t\t20171012060128_BIB17","doi-asserted-by":"crossref","unstructured":"Jobling, S., Reynolds, T., White, R., Parker, M. G., and Sumpter, J. P. (1995). A variety of environmentally persistent chemicals, including some phthalate plasticizers, are weakly estrogenic. Environ. Health Perspect.103,582\u2013587.","DOI":"10.1289\/ehp.95103582"},{"key":"key\n\t\t\t\t20171012060128_BIB18","doi-asserted-by":"crossref","unstructured":"Jobling, S., and Sumpter, J. P. (1993). Detergent components in sewage effluent are weakly oestrogenic to fish: An in vitro study using rainbow trout (Oncorhynchus mykiss) hepatocytes. Aquat. Toxicol.27,361\u2013372.","DOI":"10.1016\/0166-445X(93)90064-8"},{"key":"key\n\t\t\t\t20171012060128_BIB19","unstructured":"Katzenellenbogen, J. A., O'Mallery, B. W., and Katzenellenbogen, B. S. (1996). Tripartite steroid hormone receptor pharmacology: Interaction with multiple effector sites as a basis for the cell- and promoter specific action of these hormones. Mol. Endocrinol.10,119\u2013131."},{"key":"key\n\t\t\t\t20171012060128_BIB20","doi-asserted-by":"crossref","unstructured":"Kojima, H., Katsura, E., Takeuchi, S., Niiyama, K., and Kobayashi, K. (2004). Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells. Environ. Health Perspect.112,524\u2013531.","DOI":"10.1289\/ehp.6649"},{"key":"key\n\t\t\t\t20171012060128_BIB21","doi-asserted-by":"crossref","unstructured":"Korner, W., Hanf, V., Schuller, W., Bartsch, H., Zwirner, M., and Hagenmaier, H. (1998). Validation and application of a rapid in vitro assay for assessing the estrogenic potency of halogenated phenolic chemicals. Chemosphere31,2395\u20132407.","DOI":"10.1016\/S0045-6535(98)00297-5"},{"key":"key\n\t\t\t\t20171012060128_BIB22","doi-asserted-by":"crossref","unstructured":"Lech, J. J., Lewis, S. K., and Ren, L. (1996). In vivo estrogenic activity of nonylphenol in rainbow trout. Fundam. Appl. Toxicol.30,229\u2013232.","DOI":"10.1006\/faat.1996.0060"},{"key":"key\n\t\t\t\t20171012060128_BIB23","doi-asserted-by":"crossref","unstructured":"Loewe, S., and Mulschnek, H. (1926). Effect of combinations: Mathematical basis of problem. Arch. Exp. Pathol. Pharmakol.114,313\u2013326.","DOI":"10.1007\/BF01952257"},{"key":"key\n\t\t\t\t20171012060128_BIB24","doi-asserted-by":"crossref","unstructured":"Maekawa, S. Nishizuka, M., Heitaku, S., Kunimoto, M., Nishikawa, J., Ichikawa, K., Shimada, K., and Imagawa, M. (2004). Development of a competitive enzyme immunoassay for detection of capacity of chemicals to bind quail estrogen receptor \u03b1 and \u03b2. J. Health Sci.50,25\u201332.","DOI":"10.1248\/jhs.50.25"},{"key":"key\n\t\t\t\t20171012060128_BIB25","doi-asserted-by":"crossref","unstructured":"Nimrod, A. C., and Benson, W. H. (1998). Reproduction and development of Japanese medaka following an early life stage exposure to xenoestrogens. Aquat. Toxicol.44,141\u2013156.","DOI":"10.1016\/S0166-445X(98)00062-9"},{"key":"key\n\t\t\t\t20171012060128_BIB26","doi-asserted-by":"crossref","unstructured":"Nishihara, T., Nishikawa, J.-I., Kanayama, T., Dakeyama, F., Saito, K., Imagawa, M., Takatori, S., Kitagawa, Y., Hori, S., and Utsumi, H. (2000). Estrogenic activities of 517 chemicals by yeast two-hybrid assay. J. Health Sci.46,282\u2013298.","DOI":"10.1248\/jhs.46.282"},{"key":"key\n\t\t\t\t20171012060128_BIB27","unstructured":"Petty, D. G., Getsinger, K. D., and Woodburn, K. B. (2003). A review of the aquatic environmental fate of triclopyr and its major metabolites. J. Aquat. Plant Manag.41,69\u201375."},{"key":"key\n\t\t\t\t20171012060128_BIB28","doi-asserted-by":"crossref","unstructured":"Petty, D. G., Skogerboe, J. G., Getsinger, K. D., Foster, D. R., Houtman, B. A., Fairchild, J. F., and Anderson, L. W. (2001). The aquatic fate of triclopyr in whole pond treatments. Pest Manag. Sci.57,764\u2013775.","DOI":"10.1002\/ps.343"},{"key":"key\n\t\t\t\t20171012060128_BIB29","doi-asserted-by":"crossref","unstructured":"Plakas, S., Khoo, L., and Barron, M. G. (1992). 2,4-Dichlorophenoxyacetic acid disposition after oral administration in channel catfish. J. Agric. Food Chem.40,1236\u20131239.","DOI":"10.1021\/jf00019a032"},{"key":"key\n\t\t\t\t20171012060128_BIB30","doi-asserted-by":"crossref","unstructured":"Rajapakse, N., Ong, D., and Kortenkamp, A. (2001). Defining the impact of weakly estrogenic chemicals on the action of steroidal estrogens. Toxicol. Sci.60,296\u2013304.","DOI":"10.1093\/toxsci\/60.2.296"},{"key":"key\n\t\t\t\t20171012060128_BIB31","doi-asserted-by":"crossref","unstructured":"Rajapakse, N., Silva, E., and Kortenkamp, A. (2002). Combining xenoestrogens at levels below individual no-observed-effect concentrations dramatically enhances steroid hormone action. Environ. Health Perspect.110,917\u2013921.","DOI":"10.1289\/ehp.02110917"},{"key":"key\n\t\t\t\t20171012060128_BIB46","doi-asserted-by":"crossref","unstructured":"Rogers-Gray, T. P., Jobling, S., Morris, S., Kelly, C., Kirby, S., Janbakhsh, A. Harries, J. E., Waldock, M. J., Sumpter, J. P., and Tyler, C. R. (2000). Long-term temporal changes in the estrogenic composition of treated sewage effluent and its biological effects on fish. Environ. Sci. Technol.34,1521\u20131528.","DOI":"10.1021\/es991059c"},{"key":"key\n\t\t\t\t20171012060128_BIB32","doi-asserted-by":"crossref","unstructured":"Routledge, E. J., Sheahan, D. A., Desbrow, C., Brighty, G. C., Waldock, M., and Sumpter, J. P. (1998). Identification of estrogenic chemicals in STW effluent. 2. In vivo responses in trout and roach. Environ. Sci. Technol.32,1559\u20131565.","DOI":"10.1021\/es970796a"},{"key":"key\n\t\t\t\t20171012060128_BIB33","doi-asserted-by":"crossref","unstructured":"Routledge, E. J., and Sumpter, J. P. (1996). Estrogenic activity of surfactants and some of the degradation products assessed using a recombinant yeast screen. Environ. Toxicol. Chem.15,241\u2013248.","DOI":"10.1002\/etc.5620150303"},{"key":"key\n\t\t\t\t20171012060128_BIB34","doi-asserted-by":"crossref","unstructured":"Safe, S., and Wormke, M. (2003). Inhibitory aryl hydrocarbon receptor-estrogen receptor a cross-talk and mechanisms of action. Chem. Res. Toxicol.16,807\u2013816.","DOI":"10.1021\/tx034036r"},{"key":"key\n\t\t\t\t20171012060128_BIB35","doi-asserted-by":"crossref","unstructured":"Sumpter, J. P., and Jobling, S. (1995). Vitellogenesis as a biomarker for estrogenic contamination of the aquatic environment. Environ. Health Perspect.103,173\u2013178.","DOI":"10.1289\/ehp.95103s7173"},{"key":"key\n\t\t\t\t20171012060128_BIB37","doi-asserted-by":"crossref","unstructured":"Thompson, S., Tilton, F., Schlenk, D., and Benson, W. H. (2000). Comparative vitellogenic responses in three teleost species: Extrapolation to in situ field studies. Mar. Environ. Res.51,185\u2013189.","DOI":"10.1016\/S0141-1136(00)00077-5"},{"key":"key\n\t\t\t\t20171012060128_BIB38","doi-asserted-by":"crossref","unstructured":"Thorpe, K. L., Hutchinson, T. H., Hetheridge, M. J., Scholze, M., Sumpter, J. P., and Tyler, C. R. (2001). Assessing the biological potency of binary mixtures of environmental estrogens using vitellogenin induction in juvenile rainbow trout (Oncorhynchus mykiss). Environ. Sci. Technol.35,2476\u20132481.","DOI":"10.1021\/es001767u"},{"key":"key\n\t\t\t\t20171012060128_BIB39","doi-asserted-by":"crossref","unstructured":"Thorpe, K. L., Thomas, H. H., Hetheridge, M. J., Sumpter, J. P., and Tyler, C. R. (2000). Development of an in vivo screening assay for estrogenic chemicals using juvenile rainbow trout (Oncorhynchus mykiss). Environ. Toxicol. Chem.19,2812\u20132820.","DOI":"10.1002\/etc.5620191128"},{"key":"key\n\t\t\t\t20171012060128_BIB40","doi-asserted-by":"crossref","unstructured":"Tilton, F., Benson, W. H., and Schlenk, D. (2002). Evaluation of estrogenic activity from a municipal wastewater treatment plant with predominantly domestic input. Aquat. Toxicol.61,211\u2013224.","DOI":"10.1016\/S0166-445X(02)00058-9"},{"key":"key\n\t\t\t\t20171012060128_BIB41","unstructured":"Tomlin, C. (1994). The Pesticide Manual, pp.1341. Crop Protection Publications, Surrey, UK."},{"key":"key\n\t\t\t\t20171012060128_BIB42","doi-asserted-by":"crossref","unstructured":"Tyler, C. R., Jobling, S., and Sumpter, J. P. (1998). Endocrine disruption in wildlife: A critical review of the evidence. Crit. Rev. Toxicol.28,319\u2013361.","DOI":"10.1080\/10408449891344236"},{"key":"key\n\t\t\t\t20171012060128_BIB49","unstructured":"U.S. Environmental Protection Agency, Office of Water. Methods for the Determination of Nonconventional Pesticides in Municipal and Industrial Wastewater, Volume II. EPA Method 547: Determination of Glyphosate in Drinking Water by Direct-Aqueous-Injection HPLC, Post-Column Derivitization and Fluorescence Detection, EPA EMSL-Ci, Jully 1990."},{"key":"key\n\t\t\t\t20171012060128_BIB47","unstructured":"U.S. Environmental Protection Agency, Office of Research and Development. EPA method 549.2: Determination of Diquat and Paraquat in Drinking Water by Liquid-Solid Extraction and High Performance Liquid Chromatography with Ultraviolet Detection. Revision 1-Draft, June 1997."},{"key":"key\n\t\t\t\t20171012060128_BIB48","unstructured":"U.S. Environmental Protection Agency, Office of Water. Methods for the Determination of Nonconventional Pesticides in Municipal and Industrial Wastewater, Volume I. EPA Method 615: The Determination of Chlorinated Herbicides in Municipal and Industrial Wastewater."},{"key":"key\n\t\t\t\t20171012060128_BIB50","unstructured":"U.S. Environmental Protection Agency. SW-846, Test Methods for Evaluating Solid Waste, Physical\/Chemical Methods. EPA Method 3535A: Solid-Phase Extraction (SPE), Revision 1. January 1998. http:\/\/www.epa.gov\/sw-846\/pdfs\/3535a.pdf, July 18, 2005."},{"key":"key\n\t\t\t\t20171012060128_BIB43","doi-asserted-by":"crossref","unstructured":"Wahli, W., Dawid, I. B., Ryffel, G. U., and Weber, R. (1981). Vitellogenesis and the vitellogenin gene family. Science212,298\u2013304.","DOI":"10.1126\/science.7209528"},{"key":"key\n\t\t\t\t20171012060128_BIB44","unstructured":"Xie, L., Sopozhnikova, Y., Bawardi, O., and Schlenk, D. (2005). Evaluation of wetland and tertiary wastewater treatments for estrogenicity using in vivo and in vitro assays. Arch. Environ. Contam. Toxicol.48,82\u201387."}],"container-title":["Toxicological Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/toxsci\/article-pdf\/87\/2\/391\/4818743\/kfi249.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,3,9]],"date-time":"2019-03-09T04:29:07Z","timestamp":1552105747000},"score":1,"resource":{"primary":{"URL":"http:\/\/academic.oup.com\/toxsci\/article\/87\/2\/391\/1730753\/Evaluation-of-Estrogenic-Activities-of-Aquatic"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,7,27]]},"references-count":45,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2005,7,27]]},"published-print":{"date-parts":[[2005,10,1]]}},"URL":"https:\/\/doi.org\/10.1093\/toxsci\/kfi249","relation":{},"ISSN":["1096-0929","1096-6080"],"issn-type":[{"value":"1096-0929","type":"electronic"},{"value":"1096-6080","type":"print"}],"subject":[],"published-other":{"date-parts":[[2005,10]]},"published":{"date-parts":[[2005,7,27]]}}}