{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T20:11:27Z","timestamp":1790626287349,"version":"4.1.0"},"reference-count":48,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Toxicological Sciences"],"published-print":{"date-parts":[[2012,7,1]]},"DOI":"10.1093\/toxsci\/kfs149","type":"journal-article","created":{"date-parts":[[2012,4,27]],"date-time":"2012-04-27T02:24:03Z","timestamp":1335493443000},"page":"57-71","source":"Crossref","is-referenced-by-count":12,"title":["Mode of Action Associated With Development of Hemangiosarcoma in Mice Given Pregabalin and Assessment of Human Relevance"],"prefix":"10.1093","volume":"128","author":[{"given":"K. A.","family":"Criswell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. C.","family":"Cook","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.","family":"Wojcinski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Pegg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Herman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Wesche","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Giddings","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. T.","family":"Brady","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Anderson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2012,4,26]]},"reference":[{"issue":"4","key":"1_31842986","doi-asserted-by":"publisher","first-page":"1210","DOI":"10.2353\/ajpath.2008.080228","volume":"173","year":"2008","journal-title":"American Journal Of Pathology","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9440","issn-type":"print"},{"issue":"11","key":"2_19502893","doi-asserted-by":"publisher","first-page":"3381","DOI":"10.1681\/ASN.2005050535","volume":"16","year":"2005","journal-title":"Journal of the American Society of Nephrology","ISSN":"https:\/\/id.crossref.org\/issn\/1046-6673","issn-type":"print"},{"issue":"11","key":"3_30543132","doi-asserted-by":"publisher","first-page":"1268","DOI":"10.1164\/rccm.200710-1458OC","volume":"177","year":"2008","journal-title":"American Journal of Respiratory and Critical Care Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/1073-449X","issn-type":"print"},{"issue":"2","key":"5_6428955","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1002\/(SICI)1097-0215(20000115)85:2<223::AID-IJC12>3.0.CO;2-H","volume":"85","author":"Boivin-Ang\u00a0\u00a0le","year":"2000","journal-title":"International journal of cancer. Journal international du cancer","ISSN":"https:\/\/id.crossref.org\/issn\/0020-7136","issn-type":"print"},{"issue":"1","key":"7_9743468","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/0378-4274(92)90051-K","volume":"60","author":"Chandra","year":"1992","journal-title":"Toxicology letters","ISSN":"https:\/\/id.crossref.org\/issn\/0378-4274","issn-type":"print"},{"issue":"1","key":"8_9871673","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1016\/0378-4274(92)90064-Q","volume":"61","author":"Chandra","year":"1992","journal-title":"Toxicology letters","ISSN":"https:\/\/id.crossref.org\/issn\/0378-4274","issn-type":"print"},{"key":"9_42985176","first-page":"671","volume":"97","year":"2009","journal-title":"The American journal of cardiology","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9149","issn-type":"print"},{"issue":"1","key":"10_35047006","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1093\/toxsci\/kfp131","volume":"111","year":"2009","journal-title":"Toxicological Sciences","ISSN":"https:\/\/id.crossref.org\/issn\/1096-6080","issn-type":"print"},{"issue":"2","key":"11_17339146","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1093\/toxsci\/70.2.157","volume":"70","author":"Cunningham","year":"2002","journal-title":"Toxicological Sciences","ISSN":"https:\/\/id.crossref.org\/issn\/1096-6080","issn-type":"print"},{"issue":"5","key":"12_32308904","doi-asserted-by":"publisher","first-page":"265","DOI":"10.1159\/000151706","volume":"75","author":"Ding","year":"2008","journal-title":"Pathobiology : journal of immunopathology, molecular and cellular biology","ISSN":"https:\/\/id.crossref.org\/issn\/1015-2008","issn-type":"print"},{"issue":"5","key":"13_11423887","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1078\/0940-2993-00207","volume":"53","author":"Eiben","year":"2001","journal-title":"Experimental and toxicologic pathology : official journal of the Gesellschaft f&#x00A0;&#x00A0;r Toxikologische Pathologie","ISSN":"https:\/\/id.crossref.org\/issn\/0940-2993","issn-type":"print"},{"issue":"2","key":"14_16354133","first-page":"277","volume":"90","author":"Endo","year":"1995","journal-title":"Research communications in molecular pathology and pharmacology","ISSN":"https:\/\/id.crossref.org\/issn\/1078-0297","issn-type":"print"},{"issue":"1","key":"15_10256161","first-page":"221","volume":"37","author":"Fink","year":"1993","journal-title":"The International journal of developmental biology","ISSN":"https:\/\/id.crossref.org\/issn\/0214-6282","issn-type":"print"},{"key":"16_34524833","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1007\/s10456-008-9107-3","volume":"11","year":"2008","ISSN":"https:\/\/id.crossref.org\/issn\/1573-7209","issn-type":"print"},{"issue":"6","key":"17_34319241","doi-asserted-by":"publisher","first-page":"549","DOI":"10.1007\/s00109-009-0458-z","volume":"87","author":"Fong","year":"2009","journal-title":"Journal of molecular medicine (Berlin, Germany)","ISSN":"https:\/\/id.crossref.org\/issn\/0377-046X","issn-type":"print"},{"issue":"10","key":"19_21333997","doi-asserted-by":"publisher","first-page":"3924","DOI":"10.1182\/blood-2003-07-2535","volume":"103","year":"2004","journal-title":"Blood","ISSN":"https:\/\/id.crossref.org\/issn\/0006-4971","issn-type":"print"},{"key":"21_42985162","first-page":"428","volume":"26","year":"1988","journal-title":"Toxicologic Pathology","ISSN":"https:\/\/id.crossref.org\/issn\/0192-6233","issn-type":"print"},{"issue":"12","key":"22_29843459","doi-asserted-by":"publisher","first-page":"3879","DOI":"10.1172\/JCI32614","volume":"117","year":"2007","journal-title":"Journal of Clinical Investigation","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9738","issn-type":"print"},{"key":"23_24340753","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1177\/003591576505800503","volume":"58","year":"1965","journal-title":"PROC ROYAL SOC MED"},{"issue":"12","key":"24_31383702","doi-asserted-by":"publisher","first-page":"1263","DOI":"10.1113\/expphysiol.2008.043190","volume":"93","year":"2008","journal-title":"Experimental Physiology","ISSN":"https:\/\/id.crossref.org\/issn\/0033-5541","issn-type":"print"},{"issue":"5","key":"25_9543253","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1055\/s-0038-1648199","volume":"65","author":"Ishii","year":"1991","journal-title":"Thrombosis and haemostasis","ISSN":"https:\/\/id.crossref.org\/issn\/0340-6245","issn-type":"print"},{"key":"26_42985177","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1038\/nrc885","volume":"2","year":"2002","journal-title":"NATL REV CANCER"},{"key":"27_42985173","first-page":"83","volume":"237","year":"2010","journal-title":"Toxicology and applied pharmacology","ISSN":"https:\/\/id.crossref.org\/issn\/0041-008X","issn-type":"print"},{"issue":"3","key":"30_18051726","doi-asserted-by":"publisher","first-page":"309","DOI":"10.1093\/carcin\/bgh017","volume":"25","year":"2004","journal-title":"Carcinogenesis","ISSN":"https:\/\/id.crossref.org\/issn\/0143-3334","issn-type":"print"},{"issue":"1","key":"31_35712014","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1093\/toxsci\/kfp213","volume":"113","year":"2010","journal-title":"Toxicological Sciences","ISSN":"https:\/\/id.crossref.org\/issn\/1096-6080","issn-type":"print"},{"issue":"7","key":"32_22332579","doi-asserted-by":"publisher","first-page":"870","DOI":"10.1016\/j.exphem.2006.04.013","volume":"34","author":"Lamerato-Kozicki","year":"2006","journal-title":"Experimental hematology","ISSN":"https:\/\/id.crossref.org\/issn\/0301-472X","issn-type":"print"},{"issue":"5","key":"33_17334498","doi-asserted-by":"publisher","first-page":"713","DOI":"10.1016\/S1072-7515(02)01287-5","volume":"195","author":"Lipshutz","year":"2002","journal-title":"Journal of the American College of Surgeons","ISSN":"https:\/\/id.crossref.org\/issn\/1072-7515","issn-type":"print"},{"issue":"5","key":"34_16054313","doi-asserted-by":"publisher","first-page":"1545","DOI":"10.1084\/jem.182.5.1545","volume":"182","author":"Martin","year":"1995","journal-title":"Journal of Experimental Medicine","ISSN":"https:\/\/id.crossref.org\/issn\/0022-1007","issn-type":"print"},{"key":"35_42985178","first-page":"H1004","volume":"228","year":"2005","journal-title":"American Journal of Physiology -- Legacy Content","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9513","issn-type":"print"},{"issue":"2","key":"36_13566613","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1083\/jcb.101.2.363","volume":"101","author":"Maruyama","year":"1985","journal-title":"The Journal of Cell Biology","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9525","issn-type":"print"},{"issue":"6","key":"37_17999478","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1080\/713608373","volume":"33","author":"Meek","year":"2003","journal-title":"Critical reviews in toxicology","ISSN":"https:\/\/id.crossref.org\/issn\/1040-8444","issn-type":"print"},{"issue":"5","key":"38_22772697","doi-asserted-by":"publisher","first-page":"524","DOI":"10.1097\/01.coc.0000227544.01779.52","volume":"29","author":"Mendenhall","year":"2006","journal-title":"American journal of clinical oncology : the official publication of the American Radium Society","ISSN":"https:\/\/id.crossref.org\/issn\/0277-3732","issn-type":"print"},{"issue":"4","key":"39_11735196","first-page":"913","volume":"30","author":"Mori-Chavez","year":"1970","journal-title":"Cancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0008-5472","issn-type":"print"},{"issue":"5","key":"41_36615466","first-page":"521","volume":"31","author":"Nordstrom-O'Brien","year":"2010","journal-title":"Human mutation","ISSN":"https:\/\/id.crossref.org\/issn\/1059-7794","issn-type":"print"},{"issue":"1","key":"42_14665555","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1093\/ajcp\/101.1.109","volume":"101","author":"Ohdama","year":"1994","journal-title":"American Journal of Clinical Pathology","ISSN":"https:\/\/id.crossref.org\/issn\/0002-9173","issn-type":"print"},{"issue":"7","key":"43_30569220","doi-asserted-by":"publisher","first-page":"904","DOI":"10.1080\/01926230701748081","volume":"35","author":"Ohnishi","year":"2007","journal-title":"Toxicologic Pathology","ISSN":"https:\/\/id.crossref.org\/issn\/0192-6233","issn-type":"print"},{"issue":"1","key":"44_18906892","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1093\/toxsci\/kfi126","volume":"86","year":"2005","journal-title":"Toxicological Sciences","ISSN":"https:\/\/id.crossref.org\/issn\/1096-6080","issn-type":"print"},{"issue":"1","key":"45_6258885","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1093\/toxsci\/45.1.1","volume":"45","author":"Poteracki","year":"1998","journal-title":"Toxicological Sciences","ISSN":"https:\/\/id.crossref.org\/issn\/1096-6080","issn-type":"print"},{"issue":"6","key":"46_17652891","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1038\/nm0603-677","volume":"9","author":"Pugh","year":"2003","journal-title":"Nature medicine","ISSN":"https:\/\/id.crossref.org\/issn\/1078-8956","issn-type":"print"},{"issue":"6","key":"47_16853489","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1007\/s000180050067","volume":"53","author":"Reutelingsperger","year":"1997","journal-title":"Cellular and molecular life sciences : CMLS","ISSN":"https:\/\/id.crossref.org\/issn\/1420-682X","issn-type":"print"},{"issue":"1","key":"49_11219633","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1172\/JCI200113374","volume":"108","author":"Semenza","year":"2001","journal-title":"Journal of Clinical Investigation","ISSN":"https:\/\/id.crossref.org\/issn\/0021-9738","issn-type":"print"},{"issue":"2","key":"51_17339157","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1093\/toxsci\/70.2.252","volume":"70","author":"Siesky","year":"2002","journal-title":"Toxicological Sciences","ISSN":"https:\/\/id.crossref.org\/issn\/1096-6080","issn-type":"print"},{"key":"52_42985179","first-page":"321","volume":"16","year":"1998","journal-title":"Toxicologic Pathology","ISSN":"https:\/\/id.crossref.org\/issn\/0192-6233","issn-type":"print"},{"key":"53_42985180","doi-asserted-by":"crossref","first-page":"287","DOI":"10.2174\/187153006778249976","volume":"6","year":"2006","journal-title":"ENDOCR METAB IMMUNE DISCORD DRUG TARGETS"},{"issue":"1","key":"54_15731349","doi-asserted-by":"publisher","first-page":"113","DOI":"10.1016\/0165-5728(94)00156-I","volume":"56","author":"Tsukada","year":"1995","journal-title":"Journal of neuroimmunology","ISSN":"https:\/\/id.crossref.org\/issn\/0165-5728","issn-type":"print"},{"issue":"1","key":"56_14689909","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1006\/faat.1994.1009","volume":"22","author":"Walsh","year":"1994","journal-title":"Fundamental and applied toxicology : official journal of the Society of Toxicology","ISSN":"https:\/\/id.crossref.org\/issn\/0272-0590","issn-type":"print"},{"issue":"3","key":"57_42172176","doi-asserted-by":"publisher","first-page":"849","DOI":"10.1093\/jnci\/63.3.849","volume":"63","year":"1979","journal-title":"JNCI Journal of the National Cancer Institute","ISSN":"https:\/\/id.crossref.org\/issn\/0027-8874","issn-type":"print"},{"issue":"1A","key":"58_17057295","first-page":"375","volume":"22","author":"Woodson","year":"2002","journal-title":"Anticancer Research","ISSN":"https:\/\/id.crossref.org\/issn\/0250-7005","issn-type":"print"}],"container-title":["Toxicological Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/toxsci\/article-pdf\/128\/1\/57\/10997574\/kfs149.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,7,6]],"date-time":"2020-07-06T19:57:16Z","timestamp":1594065436000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/toxsci\/article-lookup\/doi\/10.1093\/toxsci\/kfs149"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4,26]]},"references-count":48,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2012,7,6]]},"published-print":{"date-parts":[[2012,7,1]]}},"URL":"https:\/\/doi.org\/10.1093\/toxsci\/kfs149","relation":{},"ISSN":["1096-6080","1096-0929"],"issn-type":[{"value":"1096-6080","type":"print"},{"value":"1096-0929","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,4,26]]}}}