{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:35:02Z","timestamp":1787009702985,"version":"build-2736575974"},"reference-count":31,"publisher":"Oxford University Press (OUP)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Toxicol. Sci."],"published-print":{"date-parts":[[2016,3]]},"DOI":"10.1093\/toxsci\/kfv260","type":"journal-article","created":{"date-parts":[[2015,11,27]],"date-time":"2015-11-27T20:57:39Z","timestamp":1448657859000},"page":"3-14","source":"Crossref","is-referenced-by-count":33,"title":["Beyond miR-122: Identification of MicroRNA Alterations in Blood During a Time Course of Hepatobiliary Injury and Biliary Hyperplasia in Rats"],"prefix":"10.1093","volume":"150","author":[{"given":"Rachel J.","family":"Church","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monicah","family":"Otieno","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James Eric","family":"McDuffie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bhanu","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manisha","family":"Sonee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"LeRoy","family":"Hall","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul B.","family":"Watkins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heidrun","family":"Ellinger-Ziegelbauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alison H.","family":"Harrill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2015,11,26]]},"reference":[{"key":"2016080100595682000_150.1.3.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(04)00045-5"},{"key":"2016080100595682000_150.1.3.2","doi-asserted-by":"publisher","DOI":"10.1039\/C4TX00051J"},{"key":"2016080100595682000_150.1.3.3","doi-asserted-by":"publisher","DOI":"10.1177\/0192623310373774"},{"key":"2016080100595682000_150.1.3.4","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.12214"},{"key":"2016080100595682000_150.1.3.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2010.09.022"},{"key":"2016080100595682000_150.1.3.6","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-015-0672-0"},{"key":"2016080100595682000_150.1.3.7","first-page":"221","article-title":"The liver-specific microRNA miR-122: biology and therapeutic potential","volume":"67","author":"Filipowicz","year":"2011","journal-title":"Prog. Drug Res."},{"key":"2016080100595682000_150.1.3.8","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.12.006"},{"key":"2016080100595682000_150.1.3.9","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.2012.40"},{"key":"2016080100595682000_150.1.3.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2014.05.004"},{"key":"2016080100595682000_150.1.3.11","doi-asserted-by":"publisher","DOI":"10.1006\/taap.1993.1049"},{"key":"2016080100595682000_150.1.3.12","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfu232"},{"key":"2016080100595682000_150.1.3.13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymeth.2010.01.032"},{"key":"2016080100595682000_150.1.3.14","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-11-249"},{"key":"2016080100595682000_150.1.3.15","doi-asserted-by":"publisher","DOI":"10.1038\/srep09991"},{"key":"2016080100595682000_150.1.3.16","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-15-485"},{"key":"2016080100595682000_150.1.3.17","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2014.05.005"},{"key":"2016080100595682000_150.1.3.18","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfv053"},{"key":"2016080100595682000_150.1.3.19","unstructured":"Pek S. L. Tavintharan S. Woon K. Lin L. Ong C. N. Lim S. C. Sum C. F. (2015). MicroRNAs as biomarkers of hepatotoxicity in a randomized placebo-controlled study of simvastatin and ubiquinol supplementation. Exp. Biol. Med. (Maywood). (Forthcoming). http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26429200. Accessed December 12, 2015."},{"key":"2016080100595682000_150.1.3.20","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.2089"},{"key":"2016080100595682000_150.1.3.21","doi-asserted-by":"publisher","DOI":"10.1002\/hep.24538"},{"key":"2016080100595682000_150.1.3.22","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2008.11.009"},{"key":"2016080100595682000_150.1.3.23","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2015.10.002"},{"key":"2016080100595682000_150.1.3.24","doi-asserted-by":"publisher","DOI":"10.1016\/j.diff.2008.10.001"},{"key":"2016080100595682000_150.1.3.25","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0813371106"},{"key":"2016080100595682000_150.1.3.26","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1412608111"},{"key":"2016080100595682000_150.1.3.27","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2010.147405"},{"key":"2016080100595682000_150.1.3.28","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2014.01.003"},{"key":"2016080100595682000_150.1.3.29","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0030250"},{"key":"2016080100595682000_150.1.3.30","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e318264e648"},{"key":"2016080100595682000_150.1.3.31","doi-asserted-by":"publisher","DOI":"10.1159\/000369689"}],"container-title":["Toxicological Sciences"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/academic.oup.com\/toxsci\/article-pdf\/150\/1\/3\/16690001\/kfv260.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,8,24]],"date-time":"2017-08-24T08:28:53Z","timestamp":1503563333000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/toxsci\/article-lookup\/doi\/10.1093\/toxsci\/kfv260"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11,26]]},"references-count":31,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2016,2,25]]},"published-print":{"date-parts":[[2016,3]]}},"alternative-id":["10.1093\/toxsci\/kfv260"],"URL":"https:\/\/doi.org\/10.1093\/toxsci\/kfv260","relation":{},"ISSN":["1096-6080","1096-0929"],"issn-type":[{"value":"1096-6080","type":"print"},{"value":"1096-0929","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,11,26]]}}}