{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T12:36:16Z","timestamp":1773232576300,"version":"3.50.1"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2020,11,23]],"date-time":"2020-11-23T00:00:00Z","timestamp":1606089600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,1,29]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Cassia occidentalis toxicity is thought to be uncommon; however, several cases have been described with acute hepatomyoencephalopathy with a high-mortality rate. We report a previously healthy, 2-year-old girl who developed acute liver failure after fresh seed ingestion. Without a specific antidote, we decided to implement supportive measures and medications including lactulose, sodium benzoate and N-acetylcysteine. The patient also experienced with cardiogenic shock and transient distal renal tubular acidosis, which were all spontaneously resolved. The liver chemistries returned to normal 3 months after the ingestion, without receiving liver assisted device or liver transplantation.<\/jats:p>","DOI":"10.1093\/tropej\/fmaa087","type":"journal-article","created":{"date-parts":[[2020,9,20]],"date-time":"2020-09-20T11:11:33Z","timestamp":1600600293000},"source":"Crossref","is-referenced-by-count":3,"title":["A Surviving Child from Acute Liver Failure after an Ingestion of <i>Cassia occidentalis<\/i> Seeds"],"prefix":"10.1093","volume":"67","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7558-1995","authenticated-orcid":false,"given":"Songpon","family":"Getsuwan","sequence":"first","affiliation":[{"name":"Division of Gastroenterology, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9374-8805","authenticated-orcid":false,"given":"Pornthep","family":"Tanpowpong","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satariya","family":"Trakulsrichai","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand"},{"name":"Ramathibodi Poison Center, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pattana","family":"Sornmayura","sequence":"additional","affiliation":[{"name":"Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suporn","family":"Treepongkaruna","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology, Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2020,11,23]]},"reference":[{"key":"2021031111254356000_fmaa087-B1","first-page":"23","article-title":"Clinical & pathological features of acute toxicity due to Cassia occidentalis in vertebrates","volume":"130","author":"Vashishtha","year":"2009","journal-title":"Indian J Med Res"},{"key":"2021031111254356000_fmaa087-B2","first-page":"6173","article-title":"Species diversity, usages, molecular markers and barcode of medicinal Senna species (Fabaceae, Caesalpinioideae) in Thailand","volume":"5","author":"Monkheang","year":"2011","journal-title":"J Med Plant Res"},{"key":"2021031111254356000_fmaa087-B3","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.fct.2014.03.005","article-title":"Association between children death and consumption of Cassia occidentalis seeds: clinical and experimental investigations","volume":"67","author":"Panigrahi","year":"2014","journal-title":"Food Chem Toxicol"},{"key":"2021031111254356000_fmaa087-B4","first-page":"756","article-title":"Cassia occidentalis poisoning as the probable cause of hepatomyoencephalopathy in children in western Uttar Pradesh","volume":"125","author":"Vashishtha","year":"2007","journal-title":"Indian J Med Res"},{"key":"2021031111254356000_fmaa087-B5","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1007\/s12098-012-0928-0","article-title":"Hepatomyoencephalopathy due to Cassia occidentalis Poisoning","volume":"80","author":"Nirupam","year":"2013","journal-title":"Indian J Pediatr"},{"key":"2021031111254356000_fmaa087-B6","first-page":"413","article-title":"Cassia occidentalis toxicity causes recurrent outbreaks of brain disease in children in Saharanpur","volume":"127","author":"Panwar","year":"2008","journal-title":"Indian J Med Res"},{"key":"2021031111254356000_fmaa087-B7","first-page":"523","article-title":"Recurrent annual outbreaks of a hepato-myo-encephalopathy syndrome in children in western Uttar Pradesh","volume":"125","author":"Vashishtha","year":"2007","journal-title":"India. 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