{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T22:36:11Z","timestamp":1785796571748,"version":"3.56.0"},"reference-count":34,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2020,12,7]],"date-time":"2020-12-07T00:00:00Z","timestamp":1607299200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/academic.oup.com\/journals\/pages\/open_access\/funder_policies\/chorus\/standard_publication_model"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,1,29]]},"abstract":"<jats:sec>\n                  <jats:title>Introduction<\/jats:title>\n                  <jats:p>Vitamin D deficiency (VDD) is rampant in neonates. Recommendations for supplementation are variable.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Methods<\/jats:title>\n                  <jats:p>An observational study was done on less than 32\u2009weeks of very low birth weight neonates to find prevalence of VDD (&amp;lt;20\u2009ng\/ml) at baseline; at 38\u2009\u00b1\u20092\u2009weeks post-menstrual age (PMA) after daily intake of 800\u2009IU vitamin D (vit D). Secondary objectives were to find determinants of VDD, to compare growth in deficient; vit D sufficient (VDS) neonates; to find vit D toxicity.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Results<\/jats:title>\n                  <jats:p>Of 83 neonates, 81 (97.6%) were VDD at baseline and 5 (6%) at 38\u2009\u00b1\u20092\u2009weeks PMA. Determinants for VDD at baseline were inadequate maternal sun exposure (p\u2009&amp;lt;\u20090.001) and vit D supplementation (p\u2009=\u20090.007). Factors for VDD at 38\u2009\u00b1\u20092\u2009weeks PMA were male gender (p\u2009=\u20090.049), morbidities (p\u2009=\u20090.006), ventilation &amp;gt;24\u2009h (&amp;lt;0.001), sepsis (p\u2009=\u20090.032), caffeine (p \u2264 0.001) and missed supplements (p &amp;lt; 0.001). Weight and length gain of VDD to VDS neonates were (6.70\u2009\u00b1\u20092.40 to 8.96\u2009\u00b1\u20092.21 g\/day); (0.82\u2009\u00b1\u20090.34 to 1.08\u2009\u00b1\u20090.37\u2009cm\/week), respectively (p\u2009&amp;lt;\u20090.001). Head circumference gain (cm\/week) of VDS; VDD neonates was 0.58\u2009\u00b1\u20090.09; 0.54\u2009\u00b1\u20090.06 (p = 0.054), respectively. No neonates developed vit D toxicity.<\/jats:p>\n               <\/jats:sec>\n               <jats:sec>\n                  <jats:title>Conclusions<\/jats:title>\n                  <jats:p>In preterm VLBW neonates, the prevalence of VDD was 97.6% but decreased by &amp;gt;90% at 38\u2009\u00b1\u20092\u2009weeks with a daily intake of 800\u2009IU vit D. Inadequate maternal vit D intake and sun exposure determined low baseline vit D status of neonates. Male gender, morbidities, ventilation, sepsis, caffeine, missed vitamin D supplements were determinants of poor vit D status at follow-up. Weight gain and length increments were more in the VDS group.<\/jats:p>\n               <\/jats:sec>","DOI":"10.1093\/tropej\/fmaa092","type":"journal-article","created":{"date-parts":[[2020,10,2]],"date-time":"2020-10-02T19:11:16Z","timestamp":1601665876000},"source":"Crossref","is-referenced-by-count":3,"title":["Vitamin D Status of Very Low Birth Weight Neonates at Baseline and Follow-up after Daily Intake of 800 IU Vitamin D"],"prefix":"10.1093","volume":"67","author":[{"given":"Khurshed Alam","family":"Choudhury","sequence":"first","affiliation":[{"name":"Department of Pediatrics, King George\u2019s Medical University, Uttar Pradesh, Lucknow 226003, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mala","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, C.S.M. Medical University, Uttar Pradesh, Lucknow, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0805-7370","authenticated-orcid":false,"given":"Shalini","family":"Tripathi","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, King George\u2019s Medical University, Uttar Pradesh, Lucknow 226003, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S N","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, King George\u2019s Medical University, Uttar Pradesh, Lucknow 226003, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kalpana","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, King George\u2019s Medical University, Uttar Pradesh, Lucknow 226003, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"V K","family":"Singh","sequence":"additional","affiliation":[{"name":"Community Medicine and Public Health King George\u2019s Medical University, Uttar Pradesh, Lucknow 226003, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2020,12,7]]},"reference":[{"key":"2021031111252769900_fmaa092-B1","first-page":"1","article-title":"Vitamin D for extremely preterm infants","volume":"174","author":"Jobe","year":"2016","journal-title":"J Pediatr"},{"key":"2021031111252769900_fmaa092-B2","first-page":"85","article-title":"Metabolic bone disease of prematurity","volume":"1","author":"Rustico","year":"2014","journal-title":"J Clin Transl Endocrinol"},{"key":"2021031111252769900_fmaa092-B3","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1067\/mpd.2001.116297","article-title":"Bone mineral density and body composition in boys with distal forearm fractures: a dual-energy X-ray absorptiometry study","volume":"139","author":"Goulding","year":"2001","journal-title":"J 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